Clinical Trials Updated in 2026

NCT06837506 | COMPLETED | NA

80 participants

Ultrasound Guided Rectus Sheath Block Versus Intrathecal Morphine for Postoperative Analgesia in Patients Undergoing Open Total Abdominal Hysterectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-02-20
Completion:: 2025-12-01

Conditions

Ultrasound
Rectus Sheath Block
Intrathecal Morphine
Postoperative Analgesia
Total Abdominal Hysterectomy

Interventions

DRUG

No Results Yet

NCT06833541 | COMPLETED

556 participants

Research on Gut Microbiota and Metabolomics in Diabetic Kidney Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-04-18
Completion:: 2025-12-01

Conditions

Diabetic Nephropathy Type 2
Type 2 Diabetes Mellitus (T2DM)
Chronic Kidney Disease

No Results Yet

NCT06827054 | NOT_YET_RECRUITING | PHASE2

20 participants

Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2026-09-15
Completion:: 2027-05-05

Conditions

Hematopoietic and Lymphatic System Neoplasm
Malignant Solid Neoplasm

Interventions

PROCEDURE
OTHER
DRUG
BEHAVIORAL

No Results Yet

NCT06824493 | RECRUITING

150 participants

Orthodontic Treatment on Oral Microbiota and Salivary Proteins

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-07-01
Completion:: 2027-03-01

Conditions

Orthodontics
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Caries, Dental

Interventions

OTHER

No Results Yet

NCT06824441 | ACTIVE_NOT_RECRUITING | NA

85 participants

Feasibility Usability & Acceptability Study: Symptom Reporting by Children Adolescents & Young Adults w/Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-08-18
Completion:: 2026-10-31

Conditions

Adolescent Behavior
Pediatric Cancer
Oncology

Interventions

BEHAVIORAL

No Results Yet

NCT06824025 | RECRUITING | EARLY_PHASE1

111 participants

Comparison of Nebulized Neostigmine/Atropine Versus Lignocaine in Treating Acute Post-dural Puncture Headache Following Subarachnoid Block in Parturient Undergoing Elective Cesarean Section. A Randomized, Clinical Trial.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-02-20
Completion:: 2027-01-01

Conditions

Post-Dural Puncture Headache

Interventions

DRUG

No Results Yet

NCT06822790 | RECRUITING | PHASE3

869 participants

Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-04-09
Completion:: 2028-07-31

Conditions

Hypertriglyceridemia

Interventions

DRUG

No Results Yet

NCT06819852 | NOT_YET_RECRUITING | NA

200 participants

Acute Hospital Care at Home for People Living With Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2026-08-17
Completion:: 2029-04-01

Conditions

Emergency Department Visit
Home Care Services
Dementia

Interventions

OTHER

No Results Yet

NCT06811909 | ACTIVE_NOT_RECRUITING | NA

71 participants

Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-02-14
Completion:: 2026-08-31

Conditions

Non-infected Venous Leg Ulcer
Venous Leg Ulcer
Venous Insufficiency
Venous Stasis
Venous Reflux

Interventions

OTHER

No Results Yet

NCT06803316 | COMPLETED

658 participants

Optimizing Care Delivery to Support Reengagement in PLWH Returning to HIV Care After Treatment Lapses in Zambia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2022-08-10
Completion:: 2025-07-31

Conditions

HIV Antiretroviral Therapy (ART) Adherence

No Results Yet

NCT06801899 | RECRUITING | NA

170 participants

ToPanc Trial: Survival After Total Versus Partial Pancreaticoduodenectomy for Adenocarcinoma of the Pancreatic Head, Distal Cholangiocarcinoma, and Ampullary Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2026-06-01
Completion:: 2030-10-31

Conditions

Pancreatic Cancer

Interventions

PROCEDURE

No Results Yet

NCT06801834 | RECRUITING | PHASE3

695 participants

Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-04-04
Completion:: 2029-10-31

Conditions

Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Interventions

DRUG

No Results Yet

NCT06801119 | RECRUITING | PHASE1

30 participants

Efficacy and Safety of HN2301 in Autoimmune Diseases（AIDs）

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-03-16
Completion:: 2027-12-31

Conditions

Systemic Lupus Erythematosus
Scleroderma
Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT06801041 | RECRUITING | PHASE2

20 participants

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-05-23
Completion:: 2027-03-31

Conditions

Depression
Anxiety
Cancer

Interventions

DRUG

No Results Yet

NCT06797336 | RECRUITING | PHASE1

240 participants

A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-12-19
Completion:: 2026-12-15

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT06792825 | RECRUITING | PHASE2

65 participants

HM2023-43:Ph 2 Trial of Tafasitamab With Lenalidomide+Rituximab in Treatment-naive FL and MZL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-08-07
Completion:: 2029-07-08

Conditions

Follicular Lymphoma
Marginal Zone Lymphoma

Interventions

DRUG

No Results Yet

NCT06789406 | RECRUITING | NA

55 participants

PMCF Study of the Axonics SNM System Model 5101 (R20) for the Indication of OAB

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-09-18
Completion:: 2027-01-31

Conditions

Urinary Urge Incontinence (UUI)
Urinary Frequency (UF)
Overactive Bladder (OAB)

Interventions

DEVICE

No Results Yet

NCT06787612 | RECRUITING | PHASE2

297 participants

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-05-28
Completion:: 2028-06-30

Conditions

Ovarian Cancer
Fallopian Tube Cancer
Primary Peritoneal Cancer

Interventions

DRUG

No Results Yet

NCT06777433 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Phase 2b Imaging Study of RAD101 in Participants With Suspected Recurrent Brain Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-12-13
Completion:: 2026-04-23

Conditions

Brain Metastases From Solid Tumors

Interventions

DRUG

No Results Yet

NCT06770530 | RECRUITING | PHASE4

420 participants

Introduction of Mycotic Prophylaxis At Cystectomy Trial.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-06-24
Completion:: 2027-06-30

Conditions

Cystectomy

Interventions

DRUG

No Results Yet

NCT06766851 | COMPLETED | NA

30 participants

Evaluation of the Effectiveness of Arthrocentesis Using Catheter in the Treatment of Temporamandibular Joint Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-01-13
Completion:: 2026-03-15

Conditions

TMJ Disc Disorder
Treatment
Arthrocentesis

Interventions

OTHER

No Results Yet

NCT06759649 | RECRUITING | PHASE1

200 participants

A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-01-07
Completion:: 2027-11-22

Conditions

Neoplasm
Cancer, Malignant Tumors

Interventions

DRUG

No Results Yet

NCT06757075 | RECRUITING | PHASE4

75 participants

Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-04-16
Completion:: 2027-03-31

Conditions

Pain, Postoperative

Interventions

DRUG

No Results Yet

NCT06748053 | ACTIVE_NOT_RECRUITING | PHASE2

307 participants

A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-02-10
Completion:: 2026-07-14

Conditions

Asthma

Interventions

DRUG

No Results Yet

NCT06747221 | NOT_YET_RECRUITING | NA

184 participants

Implementation Science to Enhance HIV Testing Services During Emergency Care in Kenya

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2027-02-01
Completion:: 2028-06-30

Conditions

HIV

Interventions

OTHER

No Results Yet

NCT06744517 | COMPLETED | NA

36 participants

Influence of Menstrual Cycle Phase on Adaptations to Sprint Interval Training

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-01-01
Completion:: 2026-07-30

Conditions

Healthy

Interventions

OTHER

No Results Yet

NCT06725550 | RECRUITING | NA

120 participants

Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2026-07-01
Completion:: 2030-06-28

Conditions

Sickle Cell Disease
Pain
Acupuncture
Quantitative Sensory Testing
Magnetic Resonance Imaging
Circulating Biomarkers
Electroencephalography
Functional Near-infrared Spectroscopy

Interventions

DEVICE

No Results Yet

NCT06719141 | ACTIVE_NOT_RECRUITING | PHASE3

367 participants

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-11
Completion:: 2026-10-31

Conditions

Developmental and Epileptic Encephalopathy

Interventions

DRUG

No Results Yet

NCT06717308 | RECRUITING | NA

300 participants

Evaluation of a Switchable Acrylic Adhesive Drape for Safer Removal in Negative Pressure Wound Therapy Applications.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-02-10
Completion:: 2027-02-28

Conditions

Frequency and Type of Medical Adhesive-Related Skin Injury
NPWT Drape Seal Effectiveness Rate (or Leak Incidence Rate)
Clinician Acceptability of New NPWT Drape
Patient Drop-out Rate From Prescribed NPWT Treatment
Pain Assessment During Medical Adhesive Drape Removal

Interventions

DEVICE

No Results Yet

NCT06710483 | RECRUITING | NA

50 participants

A Pilot Project to Facilitate Dental Care and Reduce Barriers For Youth With Disabilities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-08-20
Completion:: 2026-10-31

Conditions

Intellectual Disability, Variable

Interventions

BEHAVIORAL

No Results Yet

NCT06706427 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

12 participants

Safety and Efficacy Study of NGGT001 in Bietti Crystalline Corneoretinal Dystrophy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-03-21
Completion:: 2025-11-30

Conditions

Bietti Crystalline Corneoretinal Dystrophy

Interventions

BIOLOGICAL

No Results Yet

NCT06706232 | RECRUITING | PHASE2

10 participants

Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-07-07
Completion:: 2027-08-31

Conditions

Bipolar II Disorder
Depression, Bipolar
Suicidality

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT06693531 | ACTIVE_NOT_RECRUITING

368 participants

A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-22
Completion:: 2030-05-22

Conditions

Eosinophilic Esophagitis (EoE)

Interventions

DRUG

No Results Yet

NCT06691269 | RECRUITING | NA

200 participants

Photobiomodulation and Tooth Analgesia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-07-07
Completion:: 2027-06-30

Conditions

Dental Anaesthesia
Dental Pain
Dental Analgesia

Interventions

DEVICE
DRUG

No Results Yet

NCT06688435 | RECRUITING | PHASE1

60 participants

A Study to Evaluate the Safety and Preliminary Efficacy of SYS6020 CAR T-cells in Patients With Refractory Generalized Myasthenia Gravis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-03-04
Completion:: 2028-12-01

Conditions

Myasthenia Gravis

Interventions

BIOLOGICAL

No Results Yet

NCT06684834 | COMPLETED | NA

40 participants

Intermittent Carbohydrate Restriction in Cardiometabolic Health

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2023-09-05
Completion:: 2025-10-01

Conditions

Obesity and Overweight

Interventions

OTHER

No Results Yet

NCT06668922 | RECRUITING | NA

72 participants

Irritable Bowel Syndrome and Control Volunteers: Diet Challenge

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-28
Completion:: 2029-12-31

Conditions

Irritable Bowel Syndrome (IBS)

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06665620 | COMPLETED | NA

24 participants

Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-07-16
Completion:: 2026-02-01

Conditions

Suicide
Mental Health Disorder
Anhedonia

Interventions

BEHAVIORAL

No Results Yet

NCT06663878 | ACTIVE_NOT_RECRUITING | NA

9 participants

An Exploratory Study to Evaluate the Tolerability and Safety of MWAV201 in Subjects With Wilson Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-10-28
Completion:: 2031-03-31

Conditions

Wilson Disease

Interventions

GENETIC

No Results Yet

NCT06659640 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

89 participants

A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-07
Completion:: 2028-01-05

Conditions

Hereditary Hemorrhagic Telangiectasia

Interventions

DRUG

No Results Yet