Clinical Trials

NCT06801834 | RECRUITING | PHASE3

695 participants

Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-04-04
Completion:: 2029-10-31

Conditions

Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Interventions

DRUG

No Results Yet

NCT06801119 | RECRUITING | PHASE1

30 participants

Efficacy and Safety of HN2301 in Autoimmune Diseases（AIDs）

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-03-16
Completion:: 2027-12-31

Conditions

Systemic Lupus Erythematosus
Scleroderma
Rheumatoid Arthritis

Interventions

DRUG

No Results Yet

NCT06801041 | RECRUITING | PHASE2

20 participants

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-05-23
Completion:: 2027-03-31

Conditions

Depression
Anxiety
Cancer

Interventions

DRUG

No Results Yet

NCT06797336 | RECRUITING | PHASE1

240 participants

A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-12-19
Completion:: 2026-12-15

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT06792825 | RECRUITING | PHASE2

65 participants

HM2023-43:Ph 2 Trial of Tafasitamab With Lenalidomide+Rituximab in Treatment-naive FL and MZL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-08-07
Completion:: 2029-07-08

Conditions

Follicular Lymphoma
Marginal Zone Lymphoma

Interventions

DRUG

No Results Yet

NCT06789913 | RECRUITING | PHASE2

277 participants

A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-06-13
Completion:: 2031-07-31

Conditions

PIK3CA-Related Overgrowth Spectrum (PROS)
Lymphatic Malformations
Vascular Malformations
PIK3CA Mutation
CLOVES Syndrome
Klippel Trenaunay Syndrome
Megalencephaly-capillary Malformation Polymicrogyria Syndrome (MCAP)
Vascular Anomalies

Interventions

DRUG

No Results Yet

NCT06789406 | RECRUITING | NA

55 participants

PMCF Study of the Axonics SNM System Model 5101 (R20) for the Indication of OAB

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-09-18
Completion:: 2027-01-31

Conditions

Urinary Urge Incontinence (UUI)
Urinary Frequency (UF)
Overactive Bladder (OAB)

Interventions

DEVICE

No Results Yet

NCT06787612 | RECRUITING | PHASE2

297 participants

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-05-28
Completion:: 2028-06-30

Conditions

Ovarian Cancer
Fallopian Tube Cancer
Primary Peritoneal Cancer

Interventions

DRUG

No Results Yet

NCT06777433 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Phase 2b Imaging Study of RAD101 in Participants With Suspected Recurrent Brain Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-12-13
Completion:: 2026-04-23

Conditions

Brain Metastases From Solid Tumors

Interventions

DRUG

No Results Yet

NCT06771739 | NOT_YET_RECRUITING | NA

20 participants

A Pilot Unrestricted Payment Program for Early-stage Cancer Patients: the PAYMENT Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2026-09-01
Completion:: 2026-12-01

Conditions

Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet

NCT06770530 | RECRUITING | PHASE4

420 participants

Introduction of Mycotic Prophylaxis At Cystectomy Trial.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-06-24
Completion:: 2027-06-30

Conditions

Cystectomy

Interventions

DRUG

No Results Yet

NCT06766851 | COMPLETED | NA

30 participants

Evaluation of the Effectiveness of Arthrocentesis Using Catheter in the Treatment of Temporamandibular Joint Disorders

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-01-13
Completion:: 2026-03-15

Conditions

TMJ Disc Disorder
Treatment
Arthrocentesis

Interventions

OTHER

No Results Yet

NCT06759649 | RECRUITING | PHASE1

200 participants

A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-01-07
Completion:: 2027-11-22

Conditions

Neoplasm
Cancer, Malignant Tumors

Interventions

DRUG

No Results Yet

NCT06757075 | RECRUITING | PHASE4

75 participants

Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-04-16
Completion:: 2027-03-31

Conditions

Pain, Postoperative

Interventions

DRUG

No Results Yet

NCT06750978 | COMPLETED | NA

47 participants

Interventions for PSU Among College Students

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-12-18
Completion:: 2026-07-30

Conditions

Problematic Smartphone Use

Interventions

BEHAVIORAL

No Results Yet

NCT06748053 | ACTIVE_NOT_RECRUITING | PHASE2

307 participants

A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-02-10
Completion:: 2026-07-14

Conditions

Asthma

Interventions

DRUG

No Results Yet

NCT06747221 | NOT_YET_RECRUITING | NA

184 participants

Implementation Science to Enhance HIV Testing Services During Emergency Care in Kenya

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2027-02-01
Completion:: 2028-06-30

Conditions

HIV

Interventions

OTHER

No Results Yet

NCT06744517 | COMPLETED | NA

36 participants

Influence of Menstrual Cycle Phase on Adaptations to Sprint Interval Training

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-01-01
Completion:: 2026-07-30

Conditions

Healthy

Interventions

OTHER

No Results Yet

NCT06725550 | RECRUITING | NA

120 participants

Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2026-07-01
Completion:: 2030-06-28

Conditions

Sickle Cell Disease
Pain
Acupuncture
Quantitative Sensory Testing
Magnetic Resonance Imaging
Circulating Biomarkers
Electroencephalography
Functional Near-infrared Spectroscopy

Interventions

DEVICE

No Results Yet

NCT06719141 | ACTIVE_NOT_RECRUITING | PHASE3

367 participants

A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-11
Completion:: 2026-10-31

Conditions

Developmental and Epileptic Encephalopathy

Interventions

DRUG

No Results Yet

NCT06717308 | RECRUITING | NA

300 participants

Evaluation of a Switchable Acrylic Adhesive Drape for Safer Removal in Negative Pressure Wound Therapy Applications.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-02-10
Completion:: 2027-02-28

Conditions

Frequency and Type of Medical Adhesive-Related Skin Injury
NPWT Drape Seal Effectiveness Rate (or Leak Incidence Rate)
Clinician Acceptability of New NPWT Drape
Patient Drop-out Rate From Prescribed NPWT Treatment
Pain Assessment During Medical Adhesive Drape Removal

Interventions

DEVICE

No Results Yet

NCT06710483 | RECRUITING | NA

50 participants

A Pilot Project to Facilitate Dental Care and Reduce Barriers For Youth With Disabilities

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-08-20
Completion:: 2026-10-31

Conditions

Intellectual Disability, Variable

Interventions

BEHAVIORAL

No Results Yet

NCT06706427 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

12 participants

Safety and Efficacy Study of NGGT001 in Bietti Crystalline Corneoretinal Dystrophy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-03-21
Completion:: 2025-11-30

Conditions

Bietti Crystalline Corneoretinal Dystrophy

Interventions

BIOLOGICAL

No Results Yet

NCT06706232 | RECRUITING | PHASE2

10 participants

Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-07-07
Completion:: 2027-08-31

Conditions

Bipolar II Disorder
Depression, Bipolar
Suicidality

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT06693531 | ACTIVE_NOT_RECRUITING

368 participants

A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-22
Completion:: 2030-05-22

Conditions

Eosinophilic Esophagitis (EoE)

Interventions

DRUG

No Results Yet

NCT06691269 | RECRUITING | NA

200 participants

Photobiomodulation and Tooth Analgesia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-07-07
Completion:: 2027-06-30

Conditions

Dental Anaesthesia
Dental Pain
Dental Analgesia

Interventions

DEVICE
DRUG

No Results Yet

NCT06688435 | RECRUITING | PHASE1

60 participants

A Study to Evaluate the Safety and Preliminary Efficacy of SYS6020 CAR T-cells in Patients With Refractory Generalized Myasthenia Gravis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-03-04
Completion:: 2028-12-01

Conditions

Myasthenia Gravis

Interventions

BIOLOGICAL

No Results Yet

NCT06684834 | COMPLETED | NA

40 participants

Intermittent Carbohydrate Restriction in Cardiometabolic Health

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2023-09-05
Completion:: 2025-10-01

Conditions

Obesity and Overweight

Interventions

OTHER

No Results Yet

NCT06668922 | RECRUITING | NA

72 participants

Irritable Bowel Syndrome and Control Volunteers: Diet Challenge

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-28
Completion:: 2029-12-31

Conditions

Irritable Bowel Syndrome (IBS)

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06665620 | COMPLETED | NA

24 participants

Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-07-16
Completion:: 2026-02-01

Conditions

Suicide
Mental Health Disorder
Anhedonia

Interventions

BEHAVIORAL

No Results Yet

NCT06663878 | ACTIVE_NOT_RECRUITING | NA

9 participants

An Exploratory Study to Evaluate the Tolerability and Safety of MWAV201 in Subjects With Wilson Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-10-28
Completion:: 2031-03-31

Conditions

Wilson Disease

Interventions

GENETIC

No Results Yet

NCT06659640 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

89 participants

A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-07
Completion:: 2028-01-05

Conditions

Hereditary Hemorrhagic Telangiectasia

Interventions

DRUG

No Results Yet

NCT06650930 | COMPLETED | EARLY_PHASE1

20 participants

Pharmacokinetics of Oral Calcium Carbonate in Parturients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-01-23
Completion:: 2025-10-11

Conditions

Pregnancy
Pharmacokinetics
Postpartum Hemorrhage

Interventions

DRUG

No Results Yet

NCT06641908 | RECRUITING | PHASE1

52 participants

Anti-GD2 ADC M3554 in Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-08
Completion:: 2027-04-16

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06641089 | RECRUITING | PHASE3

600 participants

Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-10-15
Completion:: 2027-01-15

Conditions

Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT06641076 | ACTIVE_NOT_RECRUITING | PHASE3

960 participants

Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis Naive to Biologic Disease-Modifying Antirheumatic Drug

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-10-15
Completion:: 2027-02-04

Conditions

Arthritis, Psoriatic

Interventions

DRUG

No Results Yet

NCT06638502 | RECRUITING | PHASE1/PHASE2

80 participants

Safety of HRX215 in Patients After Minor and Major Liver Resection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-05-06
Completion:: 2027-07-31

Conditions

Liver Resection
Colorectal Carcinoma Liver Metastases

Interventions

DRUG

No Results Yet

NCT06637826 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

64 participants

Study on the Relationship Between Indoor Environment, Use of Personal Disinfection Products, and Human Health

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-10-01
Completion:: 2028-12-31

Conditions

Healthy

Interventions

BEHAVIORAL

No Results Yet

NCT06634030 | COMPLETED | PHASE2

36 participants

Evaluating rhPDGF-BB-Enhanced Wound Matrix for Head and Neck Reconstruction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2025-04-01
Completion:: 2026-07-15

Conditions

Wound Healing
Surgical Wound

Interventions

DRUG

No Results Yet

NCT06630104 | RECRUITING | NA

82 participants

Understanding the Mechanisms of Clonal and Non-clonal Cytopenia Following CAR-T Therapy for Multiple Myeloma or CD19+ Lymphoproliferative Disorder (LPD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-12
Start Date:: 2024-11-22
Completion:: 2027-12-16

Conditions

Lymphoproliferative Disorder
Multiple Myeloma

Interventions

PROCEDURE
OTHER

No Results Yet