Clinical Trials

NCT05099172 | RECRUITING | PHASE1/PHASE2

400 participants

First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-10-25

Completion:

2026-03-16

Conditions

• Advanced Non-small Cell Lung Cancer
• EGFR Mutation
• HER2 Mutation

Interventions

• DRUG

No Results Yet

NCT05092295 | ACTIVE_NOT_RECRUITING

200 participants

Head and Intraocular Trauma Tool for the Identification of Mild Traumatic Brain Injury

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2021-12-01

Completion:

2027-12-31

Conditions

• Brain Injuries, Traumatic

Interventions

• DEVICE
• DIAGNOSTIC_TEST

No Results Yet

NCT05092282 | COMPLETED

10 participants

HITT for the Identification of Mild Traumatic Brain Injury

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2021-08-01

Completion:

2025-12-31

Conditions

• Brain Injuries, Traumatic

Interventions

• DEVICE
• DIAGNOSTIC_TEST

No Results Yet

NCT05091242 | RECRUITING | PHASE2/PHASE3

336 participants

The PREVENT AGITATION Trial II - Children ≤1 Year

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-10-25

Completion:

2028-01-31

Conditions

• Emergence Delirium

Interventions

• DRUG

No Results Yet

NCT05090397 | COMPLETED | NA

26 participants

MRI-Guided High-Definition Transcranial Direct Current Stimulation (tDCS) for Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2023-07-01

Completion:

2025-03-31

Conditions

• Depression

Interventions

• DEVICE

No Results Yet

NCT05072314 | RECRUITING | PHASE3

4300 participants

Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-07-27

Completion:

2028-05-31

Conditions

• Breast Cancer
• Breast Cancer Female
• Breast Conserving Surgery
• Mastectomy

Interventions

• DRUG

No Results Yet

NCT05071612 | COMPLETED | PHASE2

294 participants

Parallel Arm Trial of AD109 and AD504 In Patients With OSA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-11-29

Completion:

2022-07-20

Conditions

• OSA - Obstructive Sleep Apnea

Interventions

• DRUG

Results Available

NCT05063916 | ACTIVE_NOT_RECRUITING | PHASE2

18 participants

Phase II Study of AK104 (Cadonilimab) for Recurrent Small Cell Neuroendocrine Carcinomas of the Cervix

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-02-28

Completion:

2027-08-01

Conditions

• Carcinomas
• Cervix Cancer
• Cervical Cancer

Interventions

• DRUG

No Results Yet

NCT05046301 | ACTIVE_NOT_RECRUITING

59 participants

Contrast-Enhanced Mammography for the Evaluation of Mammographic Microcalcifications

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2021-03-23

Completion:

2027-02-02

Conditions

• Breast Carcinoma

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT05040087 | ACTIVE_NOT_RECRUITING | NA

127 participants

Changing the Natural History of Type 2 Diabetes ("CHANGE" Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-09-01

Completion:

2026-12-31

Conditions

• Type 2 Diabetes

Interventions

• OTHER

No Results Yet

NCT05030441 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-04-01

Completion:

2030-01-31

Conditions

• Clonal Cytopenia of Undetermined Significance

Interventions

• DRUG

No Results Yet

NCT05025293 | COMPLETED | PHASE4

228 participants

Zoledronate Early to Hip Fracture Patients - Safe and Effective?

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-12-15

Completion:

2026-06-11

Conditions

• Hip Fractures
• Osteoporosis

Interventions

• DRUG

No Results Yet

NCT05016245 | COMPLETED | PHASE3

92 participants

MANDARIN (S6371)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-09-13

Completion:

2026-02-13

Conditions

• Inoperable Hepatocellular Carcinoma

Interventions

• COMBINATION_PRODUCT
• PROCEDURE

No Results Yet

NCT04987879 | COMPLETED | NA

20 participants

NASH AMPK Exercise Dosing (AMPED) Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-08-30

Completion:

2026-02-10

Conditions

• NAFLD

Interventions

• BEHAVIORAL

No Results Yet

NCT04965454 | RECRUITING | PHASE2

80 participants

Evaluation of Treatment Predictors Reflecting Beta-catenin Activation in Hepatocellular Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-03-28

Completion:

2027-12-31

Conditions

• Hepatocellular Carcinoma Non-resectable

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT04951453 | COMPLETED

150 participants

Systemic Nitrosative/Oxidative Stress in Patients With Acute Brain Injury

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2021-08-18

Completion:

2024-04-30

Conditions

• Subarachnoid Hemorrhage, Aneurysmal
• Intracerebral Hemorrhage
• Traumatic Brain Injury

Interventions

• OTHER

No Results Yet

NCT04905069 | ACTIVE_NOT_RECRUITING | NA

500 participants

Effectiveness of the SpaceOAR Vue System in Subjects With Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-12-21

Completion:

2027-12-31

Conditions

• Prostate Cancer

Interventions

• DEVICE

No Results Yet

NCT04902066 | COMPLETED | NA

259 participants

Face Your Fears: Cognitive Behavioural Virtual Reality Therapy for "Paranoia".

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-04-09

Completion:

2024-03-21

Conditions

• Paranoid Schizophrenia
• Schizophrenia and Related Disorders
• Schizophrenia Prodromal
• Schizotypal Disorder
• Paranoid Ideation
• Paranoid Delusion
• Ideas of Reference
• Psychosis Paranoid
• Psychotic Disorders
• Psychotic Paranoia
• Psychotic; Disorder, Delusional

Interventions

• OTHER

No Results Yet

NCT04862221 | ACTIVE_NOT_RECRUITING | PHASE2

44 participants

TReatment for ImmUne Mediated PathopHysiology

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-02-09

Completion:

2026-08-03

Conditions

• Acute Liver Failure
• Fulminant Hepatic Failure
• Hepatic Encephalopathy
• Acute Liver Injury
• Immune Dysregulation

Interventions

• DRUG

No Results Yet

NCT04852965 | COMPLETED

103 participants

Late Anthracycline Induced Cardiotoxicity- Childhood Cancer Survivors

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2021-10-20

Completion:

2024-04-15

Conditions

• Anthracycline Induced Cardiotoxicity

No Results Yet

NCT04849923 | COMPLETED | NA

23 participants

Validation of a Digital Twin Performing Strength Training

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-01-01

Completion:

2025-10-31

Conditions

• Healthy

Interventions

• OTHER

Results Available

NCT04838769 | ACTIVE_NOT_RECRUITING | NA

155 participants

REZŪM vs. Dual Drug Therapy for Symptomatic Benign Prostatic Hyperplasia in Sexually Active Men

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-09-15

Completion:

2025-12-11

Conditions

• Benign Prostatic Hyperplasia (BPH)

Interventions

• DEVICE
• DRUG

No Results Yet

NCT04775706 | RECRUITING | PHASE2

18 participants

Phase 2 Study to Assess the Safety, PK, and PD of Sonefpeglutide (HM15912) in SBS-IF Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-03-03

Completion:

2027-12-31

Conditions

• Short Bowel Syndrome

Interventions

• DRUG

No Results Yet

NCT04769388 | COMPLETED | PHASE2

80 participants

Osimertinib Plus Chemotherapy vs Osimertinib in EGFRm NSCLC With Persistence Week-3 ctDNA EGFRm After 1L Osimertinib

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-12-28

Completion:

2026-01-24

Conditions

• Non Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04768426 | RECRUITING | PHASE2

40 participants

Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-02-03

Completion:

2026-11-30

Conditions

• Triple Negative Breast Cancer
• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04762888 | COMPLETED | PHASE2

52 participants

68Ga-PSMA-Dual-Contrast PET/MRI or PET/CT for Early Detection of Liver Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-02-24

Completion:

2025-06-26

Conditions

• Hepatocellular Carcinoma

Interventions

• PROCEDURE
• DRUG

Results Available

NCT04748861 | ACTIVE_NOT_RECRUITING | NA

150 participants

CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-10-20

Completion:

2026-12-31

Conditions

• High Intensity Exercise
• Normal Cognition
• Exercise Intervention

Interventions

• OTHER

No Results Yet

NCT04732052 | RECRUITING | NA

60 participants

The Use of Transcranial Direct Current Stimulation (tDCS) in Adults With Developmental Disabilities

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-09-01

Completion:

2027-09-30

Conditions

• Aggression

Interventions

• DEVICE

No Results Yet

NCT04731025 | ACTIVE_NOT_RECRUITING | PHASE3

1003 participants

Local Antibiotics for Breast Implants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-01-27

Completion:

2026-09-26

Conditions

• Implant Complication
• Implant Infection
• Implant Site Infection
• Implant Capsular Contracture
• Implant Site Pocket Infection
• Implant Expulsion
• Antibiotic Side Effect

Interventions

• DRUG
• OTHER

No Results Yet

NCT04707300 | RECRUITING | PHASE1/PHASE2

10 participants

Study Evaluating the Safety and the Efficacy of Human T Lymphoid Progenitor (HTLP) Injection to Accelerate Immune Reconstitution After Umbilical Cord Blood (UCB) Transplantation in Adult Patients With Hematologic Malignancies (HTLP-ONCO)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-02-16

Completion:

2027-06-30

Conditions

• Hematologic Malignancy

Interventions

• DRUG

No Results Yet

NCT04700657 | RECRUITING

30 participants

The Prevalence of Hypoesthesia Related Keratitis in Ocular Graft Vs. Host Disease (GVHD) Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-12

Start Date:

2020-12-17

Completion:

2028-06-30

Conditions

• Ocular GVHD

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04696029 | RECRUITING | PHASE2

118 participants

DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-03-29

Completion:

2028-03-31

Conditions

• Medulloblastoma

Interventions

• DRUG

No Results Yet

NCT04693858 | ACTIVE_NOT_RECRUITING | NA

218 participants

Efficacy Trial of the CALM Intervention

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2020-12-01

Completion:

2027-08-03

Conditions

• Anxiety Disorder of Childhood

Interventions

• BEHAVIORAL

No Results Yet

NCT04665037 | RECRUITING | PHASE2

40 participants

Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-02-22

Completion:

2027-03-31

Conditions

• Invasive Fungal Infection

Interventions

• DRUG

No Results Yet

NCT04656496 | ACTIVE_NOT_RECRUITING | NA

520 participants

NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2020-12-08

Completion:

2026-09-30

Conditions

• Obesity, Childhood
• Cancer
• Survivorship

Interventions

• BEHAVIORAL

No Results Yet

NCT04631406 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

27 participants

A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-01-04

Completion:

2025-08-12

Conditions

• Ischemic Stroke

Interventions

• BIOLOGICAL

No Results Yet

NCT04609592 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

Study of PRRT in Metastatic, WHO Grade 1 or 2, SSTR Positive, GEP-NET Who Are Candidates for Cytoreductive Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-03-17

Completion:

2026-11-30

Conditions

• Gastroenteropancreatic Neuroendocrine Tumor

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04609280 | ACTIVE_NOT_RECRUITING | PHASE2

52 participants

Selective Avoidance of Nodal VolumEs at Minimal Risk (GCC 20110)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2021-03-01

Completion:

2026-12-31

Conditions

• Head and Neck Cancer
• Oropharynx Cancer
• Oropharyngeal Squamous Cell Carcinoma

Interventions

• RADIATION

No Results Yet

NCT04608487 | ACTIVE_NOT_RECRUITING | PHASE1

18 participants

Axi-cel in CNS Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2020-12-04

Completion:

2025-06-14

Conditions

• Lymphoma
• Lymphoma Cns

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04605614 | WITHDRAWN | PHASE1

0 participants

64Cu-DOTA-pembrolizumab PET for the Study of PD1 Expression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-12

Start Date:

2022-04-15

Completion:

2022-05-16

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Malignant Solid Neoplasm

Interventions

• RADIATION
• BIOLOGICAL
• PROCEDURE

No Results Yet