Clinical Trials

NCT05485961 | RECRUITING | PHASE2/PHASE3

3110 participants

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-10-21

Completion:

2029-05-22

Conditions

• End Stage Kidney Disease

Interventions

• DRUG

No Results Yet

NCT05478239 | COMPLETED | PHASE2

20 participants

ArtemiCoffee in Patients With Rising PSA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2023-08-11

Completion:

2026-07-31

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT05470491 | RECRUITING | PHASE1/PHASE2

265 participants

Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2023-01-26

Completion:

2027-07-30

Conditions

• HIV
• Hematologic Malignancies

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05468138 | ACTIVE_NOT_RECRUITING | PHASE2

94 participants

PD-1 Antibody Adjuvant Therapy for GC Patients With MSI-H After D2 Radical Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-08-01

Completion:

2029-02-28

Conditions

• MSI-H
• PD-1 Immunotherapy
• Gastric Cancer
• Adjuvant Therapy

Interventions

• DRUG

No Results Yet

NCT05467527 | COMPLETED | NA

196 participants

PACT Programme for Parents of Children With SHCN

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-06-27

Completion:

2025-11-30

Conditions

• Urologic Diseases
• Gastrointestinal Diseases
• Vascular Diseases
• Cleft Lip and Palate
• Neurodevelopmental Disorders
• Attention Deficit Hyperactivity Disorder
• Autism Spectrum Disorder
• Developmental Delay

Interventions

• BEHAVIORAL

No Results Yet

NCT05460468 | RECRUITING | NA

150 participants

Neuromodulation of Memory in Aging

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2024-03-28

Completion:

2027-06-30

Conditions

• Mild Cognitive Impairment
• MCI

Interventions

• DEVICE

No Results Yet

NCT05457010 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-11-28

Completion:

2026-10-31

Conditions

• Acute Myeloid Leukemia
• Myelodysplastic Syndromes

Interventions

• BIOLOGICAL

No Results Yet

NCT05432804 | RECRUITING | PHASE1/PHASE2

97 participants

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2023-03-20

Completion:

2027-06-30

Conditions

• Recurrent Glioblastoma, IDH-Wildtype
• Recurrent MGMT-Methylated Glioblastoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05430802 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Neoadjuvant Furmonertinib and Cisplatin/Pemetrexed as in EGFR Mutated Stage IIA-IIIB Resectable NSCLC (FORESEE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-02-24

Completion:

2025-09-01

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05422794 | RECRUITING | PHASE1

57 participants

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2023-05-18

Completion:

2027-03-31

Conditions

• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Locally Advanced Triple-Negative Breast Carcinoma
• Metastatic Triple-Negative Breast Carcinoma
• Unresectable Triple-Negative Breast Carcinoma

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT05421390 | COMPLETED | NA

60 participants

Effect of Dairy Products on Insulin Resistance

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-06-10

Completion:

2024-10-18

Conditions

• Insulin Sensitivity
• Glucose Intolerance
• PreDiabetes

Interventions

• OTHER

No Results Yet

NCT05391490 | RECRUITING | PHASE1

12 participants

Allogeneic T Cells Expressing T Cell Receptor-KDEL and the Chimeric Antigen Receptor CAT19 for the Treatment of Advanced CD19+ Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2023-02-06

Completion:

2027-02-28

Conditions

• Blood Cancer

Interventions

• GENETIC

No Results Yet

NCT05388110 | TERMINATED

14 participants

SKY Breath Intervention

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2022-04-22

Completion:

2023-12-31

Conditions

• Depression
• Anxiety Disorders

Interventions

• BEHAVIORAL

No Results Yet

NCT05376345 | TERMINATED | PHASE1

24 participants

BCMA-targeted LCAR-BCDR Cells in Patients With Relapsed/Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-09-01

Completion:

2025-05-27

Conditions

• Relapsed/Refractory Multiple Myeloma

Interventions

• BIOLOGICAL

No Results Yet

NCT05363345 | RECRUITING | NA

100 participants

Comparison of Vortic Catch V Basket Catheter and Ordinary Basket Catheter for the Removal of Bile Duct Stones

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-02-02

Completion:

2026-12-31

Conditions

• Randomized Study

Interventions

• DEVICE

No Results Yet

NCT05362929 | RECRUITING | NA

50 participants

Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2023-10-11

Completion:

2029-07-31

Conditions

• Acne Scars - Mixed Atrophic and Hypertrophic
• Hyperpigmentation
• Laser-Induced Hyperpigmentation

Interventions

• DEVICE

No Results Yet

NCT05361798 | RECRUITING | PHASE2

65 participants

A Phase II Study Evaluating T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine PDS01ADC in Localized High and Intermediate Risk Prostate Cancer Treated With Androgen Deprivation Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2023-06-12

Completion:

2027-08-01

Conditions

• Cancer Of Prostate

Interventions

• DRUG
• RADIATION

No Results Yet

NCT05353478 | ACTIVE_NOT_RECRUITING

80 participants

Reducing Opioid Prescription After Kidney Stone Removal Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2022-06-06

Completion:

2024-08-14

Conditions

• Kidney Stone

No Results Yet

NCT05350813 | RECRUITING | NA

296 participants

Impact of Procalcitonin-guided Algorithm on Early Discontinuation of Antibiotic Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2023-05-02

Completion:

2027-02-02

Conditions

• Bacterial Infections

Interventions

• PROCEDURE

No Results Yet

NCT05331183 | ACTIVE_NOT_RECRUITING | PHASE3

297 participants

Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-11-23

Completion:

2027-04-06

Conditions

• Cystic Fibrosis

Interventions

• DRUG

No Results Yet

NCT05327608 | RECRUITING | PHASE2

55 participants

Neoadjuvant Breast Cancer Time Restricted Eating

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-07-28

Completion:

2027-05-01

Conditions

• Anatomic Stage I Breast Cancer AJCC v8
• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8
• Breast Ductal Carcinoma in Situ
• HER2 Negative Breast Carcinoma
• Hormone Receptor Positive Breast Carcinoma
• Invasive Breast Carcinoma

Interventions

• OTHER

No Results Yet

NCT05313386 | WITHDRAWN | PHASE2

0 participants

Study of BXCL501 In Agitation Associated With Delirium in ICU Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-02-23

Completion:

2022-02-21

Conditions

• Agitation
• Delirium

Interventions

• DRUG

No Results Yet

NCT05303532 | ENROLLING_BY_INVITATION | PHASE3

214 participants

Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Durvalumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-04-19

Completion:

2026-12-31

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT05300685 | ACTIVE_NOT_RECRUITING | PHASE3

60 participants

Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-02-15

Completion:

2026-05-01

Conditions

• Urethral Stricture, Male

Interventions

• DRUG

No Results Yet

NCT05276830 | TERMINATED | PHASE2

5 participants

An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-02-08

Completion:

2022-04-01

Conditions

• Agitation
• Dementia

Interventions

• DRUG

Results Available

NCT05273307 | ACTIVE_NOT_RECRUITING | PHASE3

40 participants

Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-03-04

Completion:

2026-11-30

Conditions

• Head and Neck Cancer
• Taste Dysfunction

Interventions

• DRUG
• DIETARY_SUPPLEMENT

No Results Yet

NCT05271552 | COMPLETED | PHASE3

151 participants

Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY II)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-04-27

Completion:

2023-04-21

Conditions

• Agitation
• Dementia

Interventions

• DRUG

Results Available

NCT05256225 | RECRUITING | PHASE3

360 participants

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-11-16

Completion:

2027-10-31

Conditions

• Endometrial Carcinoma
• Endometrial Clear Cell Adenocarcinoma
• Endometrial Dedifferentiated Carcinoma
• Endometrial Endometrioid Adenocarcinoma
• Endometrial Mixed Cell Adenocarcinoma
• Endometrial Serous Adenocarcinoma
• Endometrial Undifferentiated Carcinoma
• Uterine Corpus Malignant Mixed Mesodermal (Mullerian) Tumor

Interventions

• PROCEDURE
• DRUG
• RADIATION
• OTHER

No Results Yet

NCT05250089 | RECRUITING | NA

40 participants

Physicians Performance After Night Shifts

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2024-01-16

Completion:

2028-01-16

Conditions

• Performance

Interventions

• OTHER

No Results Yet

NCT05239858 | RECRUITING

500 participants

International Wilson's Disease Patient Registry (iWilson Registry)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2022-06-29

Completion:

2027-12-31

Conditions

• Wilson's Disease

No Results Yet

NCT05237141 | RECRUITING | PHASE4

12 participants

Etonogestrel Implant as Emergency Contraception

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-04-01

Completion:

2027-12-31

Conditions

• Contraception

Interventions

• DRUG

No Results Yet

NCT05232825 | COMPLETED | PHASE3

236 participants

A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-05-03

Completion:

2023-03-10

Conditions

• Relapsing Multiple Sclerosis
• Primary Progressive Multiple Sclerosis

Interventions

• DRUG

Results Available

NCT05230732 | RECRUITING | NA

158 participants

Neuromodulation of Inflammation and Endothelial Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-09-01

Completion:

2027-02-27

Conditions

• Systolic Heart Failure

Interventions

• DEVICE

No Results Yet

NCT05221125 | COMPLETED | NA

86 participants

Multimodal Management of Neck and Back Pain in the Emergency Department (Multi-ED)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-06-06

Completion:

2023-04-20

Conditions

• Musculoskeletal Pain

Interventions

• BEHAVIORAL

No Results Yet

NCT05213572 | RECRUITING

200 participants

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2022-03-24

Completion:

2035-06-01

Conditions

• Mortality in Sickle Cell
• Sickle Cell Cardiopulmonary Complications
• Sickle Cell Organ Damage
• Sickle Cell Life Expectancy and Risk Factors for Early Death
• Sickle Cell Lung Disease and Sudden Death

No Results Yet

NCT05201534 | RECRUITING | NA

180 participants

Interventions in Mathematics and Cognitive Skills

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2023-05-05

Completion:

2027-08-31

Conditions

• Math Learning Disability
• Child Development
• Developmental Disability
• Learning Disabilities
• Learning Disabled
• Learning Curve
• Mathematics Disorder
• Dyscalculia
• Dyscalculia, Primary
• Dyscalculia, Acquired
• Specific Learning Disorder, With Impairment in Mathematics
• Individuality
• Behavior, Child
• Behavior and Behavior Mechanisms
• Behavior
• Decision Making
• Neuronal Plasticity
• Cognition
• Cognition Disorder
• Cognitive Dysfunction
• Cognitive Change
• Cognitive Impairment, Mild
• Cognitive Developmental Delay
• Cognitive Orientation
• Cognitive Delay, Mild
• Cognitive Deficits, Mild
• Cognitive Abnormality
• Neuroscience

Interventions

• OTHER

No Results Yet

NCT05199688 | RECRUITING | PHASE3

8 participants

A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2026-05-06

Completion:

2027-03-31

Conditions

• Neuromyelitis Optica Spectrum Disorder
• NMOSD

Interventions

• DRUG

No Results Yet

NCT05197036 | ACTIVE_NOT_RECRUITING

299 participants

A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-11

Start Date:

2021-12-21

Completion:

2026-06-11

Conditions

• Osteoarthritis
• Post-traumatic Arthritis
• Rheumatoid Arthritis

Interventions

• PROCEDURE

No Results Yet

NCT05191823 | ACTIVE_NOT_RECRUITING | NA

377 participants

Omega Tots Long Term Follow-up

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2021-12-01

Completion:

2024-06-25

Conditions

• Preterm Birth
• Child Development

Interventions

• DRUG
• DIETARY_SUPPLEMENT

Results Available

NCT05172960 | RECRUITING | NA

1234 participants

ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-11

Start Date:

2022-06-20

Completion:

2027-07-31

Conditions

• Aortic Stenosis, Severe

Interventions

• DEVICE

No Results Yet