Clinical Trials

NCT05706129 | RECRUITING | PHASE1/PHASE2
270 participants

A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-11
Start Date:
2023-03-14
Completion:
2027-06-30
Conditions
  • Clear Cell Renal Cell Cancer (ccRCC)
  • Pancreatic Ductal Adenocarcinoma (PDAC)
  • Colorectal Cancer (CRC)
  • Urothelial Carcinoma (UC)
  • Indeterminate Renal Mass (IDRM)
  • Muscle Invasive Bladder Cancer (MIBC)
  • Head and Neck Cancer (H&N)
  • Triple Negative Breast Cancer (TNBC)
  • Squamous Non-Small Cell Lung Cancer (NSCLC)
Interventions
  • DRUG
No Results Yet
NCT05642455 | RECRUITING | PHASE1/PHASE2
20 participants

SPEARHEAD-3 Pediatric Study

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-11
Start Date:
2023-09-01
Completion:
2026-10-01
Conditions
  • Synovial Sarcoma
  • Malignant Peripheral Nerve Sheath Tumor (MPNST)
  • Neuroblastoma (NBL)
  • Osteosarcoma
Interventions
  • GENETIC
No Results Yet
NCT05592626 | RECRUITING | PHASE1/PHASE2
366 participants

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-11
Start Date:
2023-01-04
Completion:
2027-09-30
Conditions
  • Advanced Solid Tumors
  • Genital Neoplasm, Female
  • Urogenital Neoplasms
  • Lung Neoplasm
  • Neoplasms by Site
  • Papillomavirus Infection
  • Epstein-Barr Virus Infections
  • Carcinoma
  • Neoplasms
  • Vulvar Neoplasms
  • Vulvar Diseases
  • Abdominal Neoplasm
  • NSCLC (Non-small Cell Lung Cancer)
  • Colorectal Cancer
Interventions
  • DRUG
  • COMBINATION_PRODUCT
No Results Yet
NCT05544526 | RECRUITING | PHASE1
12 participants

CAR T Cells to Target GD2 for DMG

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-11
Start Date:
2023-08-15
Completion:
2027-08-31
Conditions
  • Diffuse Midline Glioma, H3 K27M-Mutant
Interventions
  • BIOLOGICAL
No Results Yet
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