Pain Reduction Through Empowered Recovery (PRIME) Study

Summary

Chronic pain and depression or low mood are often experience by women who age with or into disabilities. Due to various factors women with disabilities often experience this cycle of pain and depression. Both of these conditions can be debilitating and lead to declines in health. Treating these conditions simultaneously, particularly , in older adults can be complicated due to side effects, risks of poor access to pain management and mental health care , and complications from other co occuring conditions. In order to address this cycle in older women with disabilities the investigators are testing the Women in Pain Reduction through Improved Mood and Empowerment (PRIME) study. The PRIME intervention includes four in person visits by a nurse to the women's homes where the participants set goals regarding pain and depression and the nurse helps the participants strategize ways to meet these goals. The second component of the study will be eight group sessions virtually with other participants in the study. The group sessions will be led by a clinical psychologist who will engage in Acceptance Commitment Therapy with the women.

Conditions

• Pain, Chronic
• Depressive Symptoms
• Depression
• Disability Physical

Interventions

BEHAVIORAL

PRIME Intervention

Participants who are randomized to the intervention will participate in five virtual or in person visits with a nurse where the nurse uses self regulation theory as a guide to help them set their own goals surrounding pain and depression and use tailored strategies to address these goals. The second component will include six virtual Acceptance Commitment Therapy (ACT) sessions, led by a clinical psychologist. There will be 3-5 other research participants in the sessions.

Sponsors & Collaborators

• National Institute on Aging (NIA)

  collaborator NIH

• Cornell University

  collaborator OTHER

• Johns Hopkins University

  lead OTHER

Principal Investigators

• Janiece L Taylor, PhD · Johns Hopkins School of Nursing

• Elaine Wethington, PhD · Cornell Roybal Center (Weill Cornell Medicine)

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

CROSSOVER

Eligibility

Min Age

50 Years

Sex

FEMALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2023-03-31

Primary Completion

2025-03-16

Completion

2026-05-31

Countries

• United States

Study Locations