Clinical Trials

NCT05485961 | RECRUITING | PHASE2/PHASE3

3110 participants

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-10-21
Completion:: 2029-05-22

Conditions

End Stage Kidney Disease

Interventions

DRUG

No Results Yet

NCT05478239 | COMPLETED | PHASE2

20 participants

ArtemiCoffee in Patients With Rising PSA

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2023-08-11
Completion:: 2026-07-31

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT05470491 | RECRUITING | PHASE1/PHASE2

265 participants

Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2023-01-26
Completion:: 2027-07-30

Conditions

HIV
Hematologic Malignancies

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05468138 | ACTIVE_NOT_RECRUITING | PHASE2

94 participants

PD-1 Antibody Adjuvant Therapy for GC Patients With MSI-H After D2 Radical Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-08-01
Completion:: 2029-02-28

Conditions

MSI-H
PD-1 Immunotherapy
Gastric Cancer
Adjuvant Therapy

Interventions

DRUG

No Results Yet

NCT05467527 | COMPLETED | NA

196 participants

PACT Programme for Parents of Children With SHCN

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-06-27
Completion:: 2025-11-30

Conditions

Urologic Diseases
Gastrointestinal Diseases
Vascular Diseases
Cleft Lip and Palate
Neurodevelopmental Disorders
Attention Deficit Hyperactivity Disorder
Autism Spectrum Disorder
Developmental Delay

Interventions

BEHAVIORAL

No Results Yet

NCT05460468 | RECRUITING | NA

150 participants

Neuromodulation of Memory in Aging

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2024-03-28
Completion:: 2027-06-30

Conditions

Mild Cognitive Impairment
MCI

Interventions

DEVICE

No Results Yet

NCT05457010 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-11-28
Completion:: 2026-10-31

Conditions

Acute Myeloid Leukemia
Myelodysplastic Syndromes

Interventions

BIOLOGICAL

No Results Yet

NCT05432804 | RECRUITING | PHASE1/PHASE2

97 participants

Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2023-03-20
Completion:: 2027-06-30

Conditions

Recurrent Glioblastoma, IDH-Wildtype
Recurrent MGMT-Methylated Glioblastoma

Interventions

PROCEDURE
DRUG

No Results Yet

NCT05430802 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Neoadjuvant Furmonertinib and Cisplatin/Pemetrexed as in EGFR Mutated Stage IIA-IIIB Resectable NSCLC (FORESEE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-02-24
Completion:: 2025-09-01

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05422794 | RECRUITING | PHASE1

57 participants

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2023-05-18
Completion:: 2027-03-31

Conditions

Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Locally Advanced Triple-Negative Breast Carcinoma
Metastatic Triple-Negative Breast Carcinoma
Unresectable Triple-Negative Breast Carcinoma

Interventions

DRUG
PROCEDURE
BIOLOGICAL

No Results Yet

NCT05421390 | COMPLETED | NA

60 participants

Effect of Dairy Products on Insulin Resistance

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-06-10
Completion:: 2024-10-18

Conditions

Insulin Sensitivity
Glucose Intolerance
PreDiabetes

Interventions

OTHER

No Results Yet

NCT05391490 | RECRUITING | PHASE1

12 participants

Allogeneic T Cells Expressing T Cell Receptor-KDEL and the Chimeric Antigen Receptor CAT19 for the Treatment of Advanced CD19+ Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2023-02-06
Completion:: 2027-02-28

Conditions

Blood Cancer

Interventions

GENETIC

No Results Yet

NCT05388110 | TERMINATED

14 participants

SKY Breath Intervention

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-04-22
Completion:: 2023-12-31

Conditions

Depression
Anxiety Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT05376345 | TERMINATED | PHASE1

24 participants

BCMA-targeted LCAR-BCDR Cells in Patients With Relapsed/Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-09-01
Completion:: 2025-05-27

Conditions

Relapsed/Refractory Multiple Myeloma

Interventions

BIOLOGICAL

No Results Yet

NCT05363345 | RECRUITING | NA

100 participants

Comparison of Vortic Catch V Basket Catheter and Ordinary Basket Catheter for the Removal of Bile Duct Stones

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-02-02
Completion:: 2026-12-31

Conditions

Randomized Study

Interventions

DEVICE

No Results Yet

NCT05362929 | RECRUITING | NA

50 participants

Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2023-10-11
Completion:: 2029-07-31

Conditions

Acne Scars - Mixed Atrophic and Hypertrophic
Hyperpigmentation
Laser-Induced Hyperpigmentation

Interventions

DEVICE

No Results Yet

NCT05361798 | RECRUITING | PHASE2

65 participants

A Phase II Study Evaluating T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine PDS01ADC in Localized High and Intermediate Risk Prostate Cancer Treated With Androgen Deprivation Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2023-06-12
Completion:: 2027-08-01

Conditions

Cancer Of Prostate

Interventions

DRUG
RADIATION

No Results Yet

NCT05353478 | ACTIVE_NOT_RECRUITING

80 participants

Reducing Opioid Prescription After Kidney Stone Removal Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-06-06
Completion:: 2024-08-14

Conditions

Kidney Stone

No Results Yet

NCT05350813 | RECRUITING | NA

296 participants

Impact of Procalcitonin-guided Algorithm on Early Discontinuation of Antibiotic Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2023-05-02
Completion:: 2027-02-02

Conditions

Bacterial Infections

Interventions

PROCEDURE

No Results Yet

NCT05331183 | ACTIVE_NOT_RECRUITING | PHASE3

297 participants

Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-11-23
Completion:: 2027-04-06

Conditions

Cystic Fibrosis

Interventions

DRUG

No Results Yet

NCT05327608 | RECRUITING | PHASE2

55 participants

Neoadjuvant Breast Cancer Time Restricted Eating

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-07-28
Completion:: 2027-05-01

Conditions

Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Breast Ductal Carcinoma in Situ
HER2 Negative Breast Carcinoma
Hormone Receptor Positive Breast Carcinoma
Invasive Breast Carcinoma

Interventions

OTHER

No Results Yet

NCT05313386 | WITHDRAWN | PHASE2

0 participants

Study of BXCL501 In Agitation Associated With Delirium in ICU Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-02-23
Completion:: 2022-02-21

Conditions

Agitation
Delirium

Interventions

DRUG

No Results Yet

NCT05303532 | ENROLLING_BY_INVITATION | PHASE3

214 participants

Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Durvalumab

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-04-19
Completion:: 2026-12-31

Conditions

Cancer

Interventions

DRUG

No Results Yet

NCT05300685 | ACTIVE_NOT_RECRUITING | PHASE3

60 participants

Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-02-15
Completion:: 2026-05-01

Conditions

Urethral Stricture, Male

Interventions

DRUG

No Results Yet

NCT05276830 | TERMINATED | PHASE2

5 participants

An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-02-08
Completion:: 2022-04-01

Conditions

Agitation
Dementia

Interventions

DRUG

Results Available

NCT05273307 | ACTIVE_NOT_RECRUITING | PHASE3

40 participants

Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-03-04
Completion:: 2026-11-30

Conditions

Head and Neck Cancer
Taste Dysfunction

Interventions

DRUG
DIETARY_SUPPLEMENT

No Results Yet

NCT05271552 | COMPLETED | PHASE3

151 participants

Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY II)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-04-27
Completion:: 2023-04-21

Conditions

Agitation
Dementia

Interventions

DRUG

Results Available

NCT05256225 | RECRUITING | PHASE3

360 participants

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-11-16
Completion:: 2027-10-31

Conditions

Endometrial Carcinoma
Endometrial Clear Cell Adenocarcinoma
Endometrial Dedifferentiated Carcinoma
Endometrial Endometrioid Adenocarcinoma
Endometrial Mixed Cell Adenocarcinoma
Endometrial Serous Adenocarcinoma
Endometrial Undifferentiated Carcinoma
Uterine Corpus Malignant Mixed Mesodermal (Mullerian) Tumor

Interventions

PROCEDURE
DRUG
RADIATION
OTHER

No Results Yet

NCT05250089 | RECRUITING | NA

40 participants

Physicians Performance After Night Shifts

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2024-01-16
Completion:: 2028-01-16

Conditions

Performance

Interventions

OTHER

No Results Yet

NCT05239858 | RECRUITING

500 participants

International Wilson's Disease Patient Registry (iWilson Registry)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-06-29
Completion:: 2027-12-31

Conditions

Wilson's Disease

No Results Yet

NCT05237141 | RECRUITING | PHASE4

12 participants

Etonogestrel Implant as Emergency Contraception

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-04-01
Completion:: 2027-12-31

Conditions

Contraception

Interventions

DRUG

No Results Yet

NCT05232825 | COMPLETED | PHASE3

236 participants

A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-05-03
Completion:: 2023-03-10

Conditions

Relapsing Multiple Sclerosis
Primary Progressive Multiple Sclerosis

Interventions

DRUG

Results Available

NCT05230732 | RECRUITING | NA

158 participants

Neuromodulation of Inflammation and Endothelial Function

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-09-01
Completion:: 2027-02-27

Conditions

Systolic Heart Failure

Interventions

DEVICE

No Results Yet

NCT05221125 | COMPLETED | NA

86 participants

Multimodal Management of Neck and Back Pain in the Emergency Department (Multi-ED)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-06-06
Completion:: 2023-04-20

Conditions

Musculoskeletal Pain

Interventions

BEHAVIORAL

No Results Yet

NCT05213572 | RECRUITING

200 participants

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-03-24
Completion:: 2035-06-01

Conditions

Mortality in Sickle Cell
Sickle Cell Cardiopulmonary Complications
Sickle Cell Organ Damage
Sickle Cell Life Expectancy and Risk Factors for Early Death
Sickle Cell Lung Disease and Sudden Death

No Results Yet

NCT05201534 | RECRUITING | NA

180 participants

Interventions in Mathematics and Cognitive Skills

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2023-05-05
Completion:: 2027-08-31

Conditions

Math Learning Disability
Child Development
Developmental Disability
Learning Disabilities
Learning Disabled
Learning Curve
Mathematics Disorder
Dyscalculia
Dyscalculia, Primary
Dyscalculia, Acquired
Specific Learning Disorder, With Impairment in Mathematics
Individuality
Behavior, Child
Behavior and Behavior Mechanisms
Behavior
Decision Making
Neuronal Plasticity
Cognition
Cognition Disorder
Cognitive Dysfunction
Cognitive Change
Cognitive Impairment, Mild
Cognitive Developmental Delay
Cognitive Orientation
Cognitive Delay, Mild
Cognitive Deficits, Mild
Cognitive Abnormality
Neuroscience

Interventions

OTHER

No Results Yet

NCT05199688 | RECRUITING | PHASE3

8 participants

A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2026-05-06
Completion:: 2027-03-31

Conditions

Neuromyelitis Optica Spectrum Disorder
NMOSD

Interventions

DRUG

No Results Yet

NCT05197036 | ACTIVE_NOT_RECRUITING

299 participants

A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-12-21
Completion:: 2026-06-11

Conditions

Osteoarthritis
Post-traumatic Arthritis
Rheumatoid Arthritis

Interventions

PROCEDURE

No Results Yet

NCT05191823 | ACTIVE_NOT_RECRUITING | NA

377 participants

Omega Tots Long Term Follow-up

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2021-12-01
Completion:: 2024-06-25

Conditions

Preterm Birth
Child Development

Interventions

DRUG
DIETARY_SUPPLEMENT

Results Available

NCT05172960 | RECRUITING | NA

1234 participants

ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-11
Start Date:: 2022-06-20
Completion:: 2027-07-31

Conditions

Aortic Stenosis, Severe

Interventions

DEVICE

No Results Yet