Clinical Trials

NCT05308264 | RECRUITING | PHASE1/PHASE2

86 participants

Study of R289 in Patients With Lower-risk Myelodysplastic Syndromes (LR MDS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-09-12

Completion:

2026-08-31

Conditions

• Low Risk Myelodysplastic Syndromes

Interventions

• DRUG

No Results Yet

NCT05285891 | RECRUITING | PHASE4

123 participants

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-02-07

Completion:

2030-05-01

Conditions

• Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT05264974 | RECRUITING | PHASE1

18 participants

Novel RNA-lipid Particle (RNA-LP) Vaccine for Anti-PD-1 Antibody Therapy Sensitization

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2026-03-17

Completion:

2026-12-31

Conditions

• Melanoma
• Soft Tissue Sarcoma

Interventions

• BIOLOGICAL

No Results Yet

NCT05262556 | COMPLETED | PHASE1

15 participants

NP-101 (TQ Formula) With Nivolumab and Ipilimumab in Advanced or Metastatic Extra-pulmonary Neuroendocrine Carcinomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-12-15

Completion:

2025-10-27

Conditions

• Gastroenteropancreatic Neuroendocrine Tumor
• Gastroenteropancreatic Neuroendocrine Neoplasm
• Neuroendocrine Carcinoma
• Mixed Neuroendocrine-Non Neuroendocrine Neoplasm

Interventions

• DRUG

No Results Yet

NCT05246033 | COMPLETED | PHASE2

24 participants

A Dose Escalation Trial Evaluating Safety, Efficacy, and Pharmacokinetics of Multiple Subcutaneous Doses of TransCon CNP Administered Once Weekly in Children With Achondroplasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-01-05

Completion:

2023-03-15

Conditions

• Achondroplasia

Interventions

• DRUG

No Results Yet

NCT05236673 | COMPLETED

676 participants

Jardiance® Post Marketing Surveillance (PMS) in Korean Patients With Chronic Heart Failure

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2022-07-28

Completion:

2025-04-30

Conditions

• Heart Failure

Interventions

• DRUG

Results Available

NCT05201014 | TERMINATED

112 participants

Cancer Survivor Cardiomyopathy Detection

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2022-03-03

Completion:

2026-02-09

Conditions

• Cardiovascular Diseases
• Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05199324 | COMPLETED | PHASE4

720 participants

Early Oral Switch for Uncomplicated Gram-negative Bacteraemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-06-03

Completion:

2026-05-24

Conditions

• Gram-negative Bacteraemia

Interventions

• DRUG

No Results Yet

NCT05198674 | ACTIVE_NOT_RECRUITING | NA

1899 participants

SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-10-20

Completion:

2026-11-30

Conditions

• Hypertension
• Vascular Diseases
• Cardiovascular Diseases
• Chronic Kidney Diseases
• Diabetes Mellitus

Interventions

• DEVICE

No Results Yet

NCT05195398 | RECRUITING | NA

60 participants

TDCS to Improve Post-Stroke Cognitive Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-09-01

Completion:

2027-08-31

Conditions

• Stroke
• Stroke Sequelae
• Cognitive Impairment

Interventions

• DEVICE

No Results Yet

NCT05180773 | RECRUITING | PHASE4

250 participants

Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-07-27

Completion:

2028-06-30

Conditions

• Peripartum Cardiomyopathy, Postpartum

Interventions

• DRUG

No Results Yet

NCT05178862 | TERMINATED | PHASE3

68 participants

A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-08-03

Completion:

2025-11-07

Conditions

• Candidiasis, Invasive
• Candidemia

Interventions

• DRUG

Results Available

NCT05169515 | ACTIVE_NOT_RECRUITING | PHASE1

121 participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-10-26

Completion:

2029-09-15

Conditions

• Non-Hodgkin Lymphoma

Interventions

• DRUG

No Results Yet

NCT05153239 | COMPLETED | PHASE3

705 participants

Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-07-22

Completion:

2026-04-10

Conditions

• Relapsed Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05145764 | COMPLETED | PHASE2

76 participants

Suvorexant as an Adjunct to Buprenorphine in Persons Who Use Fentanyl

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-03-30

Completion:

2026-08-03

Conditions

• Suvorexant
• Placebo
• Opioid Use Disorder

Interventions

• DRUG

No Results Yet

NCT05134012 | ACTIVE_NOT_RECRUITING | PHASE3

215 participants

RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-05-08

Completion:

2026-10-31

Conditions

• Coronary Artery Disease

Interventions

• DRUG

No Results Yet

NCT05114421 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Pembrolizumab and Lenvatinib for the Treatment of Serous Ovarian Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-11-09

Completion:

2027-01-31

Conditions

• High Grade Fallopian Tube Serous Adenocarcinoma
• High Grade Ovarian Serous Adenocarcinoma
• Peritoneal High Grade Serous Adenocarcinoma
• Recurrent High Grade Fallopian Tube Serous Adenocarcinoma
• Recurrent High Grade Ovarian Serous Adenocarcinoma
• Recurrent Primary Peritoneal High Grade Serous Adenocarcinoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT05111561 | RECRUITING | PHASE1

42 participants

Testing the Combination of the Anticancer Drugs ZEN003694 and Binimetinib in Patients With Advanced/Metastatic or Unresectable Solid Tumors With RAS Alterations and Triple Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-08-02

Completion:

2027-03-14

Conditions

• Advanced Malignant Solid Neoplasm
• Metastatic Malignant Solid Neoplasm
• Refractory Malignant Solid Neoplasm
• Triple-Negative Breast Carcinoma
• Unresectable Malignant Solid Neoplasm

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05108519 | RECRUITING

170 participants

Complications and Clinical Response in Cancer Patients Treated With Anti-VEGF-Related Therapies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2019-04-08

Completion:

2027-02-02

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Malignant Solid Neoplasm

Interventions

• OTHER

No Results Yet

NCT05107869 | COMPLETED | NA

23 participants

Effect of Plasma Ceramides on Peripheral Vascular Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2023-05-01

Completion:

2025-12-01

Conditions

• Peripheral Vascular Disease
• Lipid Disorder
• Endothelial Dysfunction

Interventions

• OTHER

No Results Yet

NCT05097586 | RECRUITING | NA

156 participants

RCT of At-Home tDCS for Depression in Pregnancy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-11-08

Completion:

2027-03-31

Conditions

• Major Depression
• Pregnancy
• Postpartum Depression

Interventions

• DEVICE
• OTHER

No Results Yet

NCT05075733 | COMPLETED

172 participants

Current Scope of Practice of Today's Hepatopancreatobiliary Surgeons: A Survey of AHPBA Members

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2014-12-01

Completion:

2015-02-01

Conditions

• Scope of Practice of Today's Hepatopancreatobiliary Surgeons

Interventions

• OTHER

No Results Yet

NCT05075603 | COMPLETED | PHASE1

17 participants

Relapsed/Refractory Large B-cell Lymphoma With NT-I7 Post-CD19 CAR T-cell Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-07-29

Completion:

2024-12-18

Conditions

• Refractory Diffuse Large B-cell Lymphoma
• Recurrent Diffuse Large B-Cell Lymphoma
• High-grade B-cell Lymphoma
• DLBCL Arising From Follicular Lymphoma
• Primary Mediastinal Large B-cell Lymphoma

Interventions

• DRUG

Results Available

NCT05071963 | ACTIVE_NOT_RECRUITING

246 participants

INSPIRE Pipeline™ Shield Post Approval Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2021-12-20

Completion:

2027-01-31

Conditions

• Intracranial Aneurysm

Interventions

• DEVICE

No Results Yet

NCT05057676 | ACTIVE_NOT_RECRUITING | NA

400 participants

Autoimmune Intervention Mastery Course Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-12-01

Completion:

2027-12-01

Conditions

• Multiple Sclerosis
• Clinically Isolated Syndrome
• Fibromyalgia
• Post Acute Sequelae of COVID-19
• Cancer in Remission With Persisting Fatigue

Interventions

• BEHAVIORAL

No Results Yet

NCT05047172 | ACTIVE_NOT_RECRUITING | PHASE3

1683 participants

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-08-02

Completion:

2027-01-31

Conditions

• Intracranial Arteriosclerosis
• Stroke

Interventions

• DRUG
• OTHER

No Results Yet

NCT05046080 | RECRUITING

70 participants

Clinicopathologic and Ancillary Testing of Primary Clear Cell Carcinoma of the Cervix

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2021-08-06

Completion:

2026-09-29

Conditions

• Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type

Interventions

• OTHER

No Results Yet

NCT05042544 | RECRUITING

60000 participants

The Australian HCV Point-of-Care Testing Program

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2022-02-23

Completion:

2029-06-30

Conditions

• Hepatitis C

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05041374 | RECRUITING

4000 participants

Evaluation of Patients With Gastrointestinal Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2022-01-04

Completion:

2035-12-31

Conditions

• Lower GI Disease
• Gastrointestinal Diseases

No Results Yet

NCT05041140 | RECRUITING

25 participants

Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2024-08-14

Completion:

2027-07-20

Conditions

• Pulmonary
• Pneumonia
• Hematopoietic System--Cancer

Interventions

• DEVICE

No Results Yet

NCT05035082 | COMPLETED | PHASE4

1018 participants

A Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-09-01

Completion:

2025-06-18

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

Results Available

NCT05022446 | RECRUITING

250 participants

The Impact of COVID-19 on Pulmonary Procedures

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2020-11-11

Completion:

2027-02-02

Conditions

• COVID-19 Infection
• Hematopoietic and Lymphoid Cell Neoplasm
• Malignant Solid Neoplasm

Interventions

• OTHER

No Results Yet

NCT05007353 | COMPLETED | NA

1212 participants

The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER) Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-08-23

Completion:

2025-12-01

Conditions

• Cognitive Impairment
• Alzheimer Disease
• Vascular Cognitive Impairment
• Dementia
• Brain Diseases
• Central Nervous System Diseases
• Nervous System Diseases
• Neurocognitive Disorders
• Mental Disorders
• Cognition Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05001750 | RECRUITING | PHASE1

84 participants

Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-06-14

Completion:

2028-08-31

Conditions

• Subarachnoid Hemorrhage
• Intracerebral Hemorrhage
• Ventriculitis, Cerebral
• Hydrocephalus

Interventions

• DRUG

No Results Yet

NCT04991454 | RECRUITING | PHASE2

20 participants

Xenon MRI Pulm Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-09-01

Completion:

2027-07-31

Conditions

• Pulmonary Hypertension
• Pulmonary Arterial Hypertension

Interventions

• DRUG

No Results Yet

NCT04981171 | COMPLETED | NA

180 participants

Electro-thumbtack Needle Therapy for Chronic Neck Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-06-06

Completion:

2024-07-13

Conditions

• Neck Pain

Interventions

• PROCEDURE

No Results Yet

NCT04972526 | RECRUITING

1000 participants

Resuscitative TEE Collaborative Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2020-12-01

Completion:

2027-12-15

Conditions

• Cardiac Arrest
• Cardiac Arrest Circulatory
• Cardiac Arrest, Out-Of-Hospital
• Shock
• Hemodynamic Instability

No Results Yet

NCT04971954 | RECRUITING | NA

48 participants

Using Nicotine to Reverse Age-related Auditory Processing Deficits

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2022-02-01

Completion:

2026-12-31

Conditions

• Auditory Perceptual Impairment
• Aging

Interventions

• OTHER

No Results Yet

NCT04939142 | COMPLETED | PHASE3

154 participants

A Study of Evaluating the Safety and Efficacy of ATG-010, Bortezomib, and Dexamethasone (SVd) Versus Bortezomib and Dexamethasone (Vd) in Patients With Relapsed or Refractory Multiple Myeloma (RRMM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-10

Start Date:

2021-07-12

Completion:

2024-08-26

Conditions

• Relapsed or Refractory Multiple Myeloma

Interventions

• COMBINATION_PRODUCT

Results Available

NCT04923178 | RECRUITING

1100 participants

A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-10

Start Date:

2022-10-24

Completion:

2041-12-01

Conditions

• Urothelial Cancer
• Bladder Cancer
• Genitourinary Cancer
• Urogenital Neoplasms
• Urogenital Cancer

No Results Yet