Clinical Trials

NCT05198674 | ACTIVE_NOT_RECRUITING | NA

1899 participants

SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-10-20
Completion:: 2026-11-30

Conditions

Hypertension
Vascular Diseases
Cardiovascular Diseases
Chronic Kidney Diseases
Diabetes Mellitus

Interventions

DEVICE

No Results Yet

NCT05195398 | RECRUITING | NA

60 participants

TDCS to Improve Post-Stroke Cognitive Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-09-01
Completion:: 2027-08-31

Conditions

Stroke
Stroke Sequelae
Cognitive Impairment

Interventions

DEVICE

No Results Yet

NCT05180773 | RECRUITING | PHASE4

250 participants

Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-07-27
Completion:: 2028-06-30

Conditions

Peripartum Cardiomyopathy, Postpartum

Interventions

DRUG

No Results Yet

NCT05178862 | TERMINATED | PHASE3

68 participants

A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-08-03
Completion:: 2025-11-07

Conditions

Candidiasis, Invasive
Candidemia

Interventions

DRUG

Results Available

NCT05169515 | ACTIVE_NOT_RECRUITING | PHASE1

121 participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-10-26
Completion:: 2029-09-15

Conditions

Non-Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT05153239 | COMPLETED | PHASE3

705 participants

Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-07-22
Completion:: 2026-04-10

Conditions

Relapsed Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05145764 | COMPLETED | PHASE2

76 participants

Suvorexant as an Adjunct to Buprenorphine in Persons Who Use Fentanyl

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-03-30
Completion:: 2026-08-03

Conditions

Suvorexant
Placebo
Opioid Use Disorder

Interventions

DRUG

No Results Yet

NCT05134012 | ACTIVE_NOT_RECRUITING | PHASE3

215 participants

RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-05-08
Completion:: 2026-10-31

Conditions

Coronary Artery Disease

Interventions

DRUG

No Results Yet

NCT05114421 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Pembrolizumab and Lenvatinib for the Treatment of Serous Ovarian Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-11-09
Completion:: 2027-01-31

Conditions

High Grade Fallopian Tube Serous Adenocarcinoma
High Grade Ovarian Serous Adenocarcinoma
Peritoneal High Grade Serous Adenocarcinoma
Recurrent High Grade Fallopian Tube Serous Adenocarcinoma
Recurrent High Grade Ovarian Serous Adenocarcinoma
Recurrent Primary Peritoneal High Grade Serous Adenocarcinoma

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT05111561 | RECRUITING | PHASE1

42 participants

Testing the Combination of the Anticancer Drugs ZEN003694 and Binimetinib in Patients With Advanced/Metastatic or Unresectable Solid Tumors With RAS Alterations and Triple Negative Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-08-02
Completion:: 2027-03-14

Conditions

Advanced Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm
Refractory Malignant Solid Neoplasm
Triple-Negative Breast Carcinoma
Unresectable Malignant Solid Neoplasm

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05108519 | RECRUITING

170 participants

Complications and Clinical Response in Cancer Patients Treated With Anti-VEGF-Related Therapies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-04-08
Completion:: 2027-02-02

Conditions

Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet

NCT05107869 | COMPLETED | NA

23 participants

Effect of Plasma Ceramides on Peripheral Vascular Function

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-05-01
Completion:: 2025-12-01

Conditions

Peripheral Vascular Disease
Lipid Disorder
Endothelial Dysfunction

Interventions

OTHER

No Results Yet

NCT05097586 | RECRUITING | NA

156 participants

RCT of At-Home tDCS for Depression in Pregnancy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-11-08
Completion:: 2027-03-31

Conditions

Major Depression
Pregnancy
Postpartum Depression

Interventions

DEVICE
OTHER

No Results Yet

NCT05075733 | COMPLETED

172 participants

Current Scope of Practice of Today's Hepatopancreatobiliary Surgeons: A Survey of AHPBA Members

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2014-12-01
Completion:: 2015-02-01

Conditions

Scope of Practice of Today's Hepatopancreatobiliary Surgeons

Interventions

OTHER

No Results Yet

NCT05075603 | COMPLETED | PHASE1

17 participants

Relapsed/Refractory Large B-cell Lymphoma With NT-I7 Post-CD19 CAR T-cell Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-07-29
Completion:: 2024-12-18

Conditions

Refractory Diffuse Large B-cell Lymphoma
Recurrent Diffuse Large B-Cell Lymphoma
High-grade B-cell Lymphoma
DLBCL Arising From Follicular Lymphoma
Primary Mediastinal Large B-cell Lymphoma

Interventions

DRUG

Results Available

NCT05071963 | ACTIVE_NOT_RECRUITING

246 participants

INSPIRE Pipeline™ Shield Post Approval Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-12-20
Completion:: 2027-01-31

Conditions

Intracranial Aneurysm

Interventions

DEVICE

No Results Yet

NCT05057676 | ACTIVE_NOT_RECRUITING | NA

400 participants

Autoimmune Intervention Mastery Course Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-12-01
Completion:: 2027-12-01

Conditions

Multiple Sclerosis
Clinically Isolated Syndrome
Fibromyalgia
Post Acute Sequelae of COVID-19
Cancer in Remission With Persisting Fatigue

Interventions

BEHAVIORAL

No Results Yet

NCT05047172 | ACTIVE_NOT_RECRUITING | PHASE3

1683 participants

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-08-02
Completion:: 2027-01-31

Conditions

Intracranial Arteriosclerosis
Stroke

Interventions

DRUG
OTHER

No Results Yet

NCT05046080 | RECRUITING

70 participants

Clinicopathologic and Ancillary Testing of Primary Clear Cell Carcinoma of the Cervix

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-08-06
Completion:: 2026-09-29

Conditions

Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type

Interventions

OTHER

No Results Yet

NCT05042544 | RECRUITING

60000 participants

The Australian HCV Point-of-Care Testing Program

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-02-23
Completion:: 2029-06-30

Conditions

Hepatitis C

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05041374 | RECRUITING

4000 participants

Evaluation of Patients With Gastrointestinal Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-01-04
Completion:: 2035-12-31

Conditions

Lower GI Disease
Gastrointestinal Diseases

No Results Yet

NCT05041140 | RECRUITING

25 participants

Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2024-08-14
Completion:: 2027-07-20

Conditions

Pulmonary
Pneumonia
Hematopoietic System--Cancer

Interventions

DEVICE

No Results Yet

NCT05035082 | COMPLETED | PHASE4

1018 participants

A Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-09-01
Completion:: 2025-06-18

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

Results Available

NCT05022446 | RECRUITING

250 participants

The Impact of COVID-19 on Pulmonary Procedures

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-11-11
Completion:: 2027-02-02

Conditions

COVID-19 Infection
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet

NCT05007353 | COMPLETED | NA

1212 participants

The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-08-23
Completion:: 2025-12-01

Conditions

Cognitive Impairment
Alzheimer Disease
Vascular Cognitive Impairment
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders
Cognition Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05001750 | RECRUITING | PHASE1

84 participants

Prophylactic Antibiotics Useful With Antibiotic Impregnated External Ventricular Drains (EVDs)?

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-06-14
Completion:: 2028-08-31

Conditions

Subarachnoid Hemorrhage
Intracerebral Hemorrhage
Ventriculitis, Cerebral
Hydrocephalus

Interventions

DRUG

No Results Yet

NCT04991454 | RECRUITING | PHASE2

20 participants

Xenon MRI Pulm Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-09-01
Completion:: 2027-07-31

Conditions

Pulmonary Hypertension
Pulmonary Arterial Hypertension

Interventions

DRUG

No Results Yet

NCT04981171 | COMPLETED | NA

180 participants

Electro-thumbtack Needle Therapy for Chronic Neck Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-06-06
Completion:: 2024-07-13

Conditions

Neck Pain

Interventions

PROCEDURE

No Results Yet

NCT04972526 | RECRUITING

1000 participants

Resuscitative TEE Collaborative Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2020-12-01
Completion:: 2027-12-15

Conditions

Cardiac Arrest
Cardiac Arrest Circulatory
Cardiac Arrest, Out-Of-Hospital
Shock
Hemodynamic Instability

No Results Yet

NCT04971954 | RECRUITING | NA

48 participants

Using Nicotine to Reverse Age-related Auditory Processing Deficits

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-02-01
Completion:: 2026-12-31

Conditions

Auditory Perceptual Impairment
Aging

Interventions

OTHER

No Results Yet

NCT04939142 | COMPLETED | PHASE3

154 participants

A Study of Evaluating the Safety and Efficacy of ATG-010, Bortezomib, and Dexamethasone (SVd) Versus Bortezomib and Dexamethasone (Vd) in Patients With Relapsed or Refractory Multiple Myeloma (RRMM)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-07-12
Completion:: 2024-08-26

Conditions

Relapsed or Refractory Multiple Myeloma

Interventions

COMBINATION_PRODUCT

Results Available

NCT04923178 | RECRUITING

1100 participants

A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-10-24
Completion:: 2041-12-01

Conditions

Urothelial Cancer
Bladder Cancer
Genitourinary Cancer
Urogenital Neoplasms
Urogenital Cancer

No Results Yet

NCT04907825 | COMPLETED | PHASE4

14 participants

A Trial of Pharmacist Management of Oral Anticoagulation THerapy in the communitY for AF

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2023-03-13
Completion:: 2025-08-31

Conditions

Atrial Fibrillation
Stroke

Interventions

DRUG

No Results Yet

NCT04893226 | RECRUITING | NA

164 participants

Circadian Rhythms in Postmenopausal Women

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-10-19
Completion:: 2027-01-31

Conditions

Metabolic Syndrome
Postmenopausal Symptoms

Interventions

BEHAVIORAL

No Results Yet

NCT04892953 | RECRUITING | PHASE2

51 participants

Local Consolidative Therapy and Durvalumab for Oligoprogressive and Polyprogressive Stage III NSCLC After Chemoradiation and Anti-PD-L1 Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-07-07
Completion:: 2026-09-30

Conditions

Stage III Lung Cancer AJCC v8
Stage III Lung Non-Small Cell Cancer AJCC v7
Stage IIIA Lung Cancer AJCC v8
Stage IIIA Lung Non-Small Cell Cancer AJCC v7
Stage IIIB Lung Cancer AJCC v8
Stage IIIB Lung Non-Small Cell Cancer AJCC v7
Stage IIIC Lung Cancer AJCC v8

Interventions

DRUG
BIOLOGICAL
PROCEDURE
OTHER

No Results Yet

NCT04887688 | RECRUITING | NA

16 participants

Exciflex Electroceutical Banadage for Chronic Wound Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2022-10-05
Completion:: 2029-07-30

Conditions

Chronic Wound
Diabetes
Spinal Cord Injury
Ischemic Wound

Interventions

DEVICE

No Results Yet

NCT04858438 | WITHDRAWN | NA

0 participants

Pain After Insufflation for Robotic Sacrocolpopexy (PAIRS) Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-04-02
Completion:: 2025-02-01

Conditions

Pelvic Organ Prolapse

Interventions

PROCEDURE

No Results Yet

NCT04855435 | RECRUITING | PHASE1

106 participants

Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-04-12
Completion:: 2027-03-31

Conditions

Advanced Solid Tumor
Uveal Melanoma, Metastatic
Cutaneous Melanoma

Interventions

DRUG

No Results Yet

NCT04853251 | RECRUITING | PHASE4

188 participants

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2021-12-14
Completion:: 2027-07-30

Conditions

Neovascular Age-related Macular Degeneration

Interventions

DEVICE
DRUG

No Results Yet

NCT04744532 | COMPLETED | PHASE1/PHASE2

46 participants

iPSC-based Drug Repurposing for ALS Medicine (iDReAM) Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-10
Start Date:: 2019-03-19
Completion:: 2024-01-16

Conditions

Amyotrophic Lateral Sclerosis

Interventions

DRUG

No Results Yet