Clinical Trials Updated in 2026

NCT06061614 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

15 participants

Safety and Efficacy Study of NGGT002 in PKU Adult Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-03-30
Completion:: 2028-12-30

Conditions

Phenylketonurias

Interventions

GENETIC

No Results Yet

NCT06060743 | COMPLETED | NA

88 participants

Examining the Effect of Mobile Application on Insulin Use Perception and Self-Management

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-01-01
Completion:: 2024-05-01

Conditions

Type 2 Diabetes Treated With Insulin

Interventions

OTHER

No Results Yet

NCT06056895 | ACTIVE_NOT_RECRUITING | PHASE2

12 participants

Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-11-08
Completion:: 2027-01-31

Conditions

Unresectable Clinical Stage III Merkel Cell Carcinoma AJCC v8
Clinical Stage IV Merkel Cell Carcinoma AJCC v8
Merkel Cell Carcinoma

Interventions

PROCEDURE
BIOLOGICAL
DRUG

No Results Yet

NCT06056297 | RECRUITING | PHASE3

176 participants

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-06-06
Completion:: 2027-09-30

Conditions

Neutropenia

Interventions

DRUG

No Results Yet

NCT06041581 | ENROLLING_BY_INVITATION | NA

200 participants

SHADES Mechanistic Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-04-25
Completion:: 2027-07-31

Conditions

Insomnia
Insomnia Chronic
Insomnia, Primary
Sleep Disturbance
Sleep Disorder
Cardiovascular Diseases
Heart Diseases
Coronary Artery Disease
Stroke
Autonomic Dysfunction
Systemic Inflammatory Response
Metabolic Disease

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT06030128 | COMPLETED | NA

150 participants

Core Stabilization Exercise Therapy in Chronic Lower Back Back Management in Community Dwelling Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-09-15
Completion:: 2025-05-01

Conditions

Chronic Low-back Pain
Older Adults
Core Stabilization Exercise Therapy

Interventions

BEHAVIORAL

No Results Yet

NCT05995821 | RECRUITING

1250 participants

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2016-08-25
Completion:: 2028-08-25

Conditions

Head and Neck Cancer
Lung Cancer
Gastrointestinal Cancer

Interventions

OTHER

No Results Yet

NCT05990465 | RECRUITING | PHASE1

12 participants

LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-02-06
Completion:: 2028-07-31

Conditions

Non Hodgkin Lymphoma
Diffuse Large B Cell Lymphoma
Follicular Lymphoma
Marginal Zone Lymphoma
Mantle Cell Lymphoma
Burkitt Lymphoma

Interventions

DRUG

No Results Yet

NCT05988385 | RECRUITING | NA

200 participants

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-08-29
Completion:: 2027-06-30

Conditions

Obstructive Sleep Apnea
Cognitive Decline

Interventions

DEVICE

No Results Yet

NCT05984238 | COMPLETED | NA

33 participants

A Trial to Evaluate Safety, Feasibility and Efficacy of Endoscopic Duodenal PEF Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-08-03
Completion:: 2025-03-21

Conditions

Diabetes Mellitus, Type 2

Interventions

DEVICE
DRUG
OTHER

No Results Yet

NCT05952856 | COMPLETED | PHASE3

2912 participants

A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-08-10
Completion:: 2025-07-28

Conditions

Hypercholesterolemia
Familial Hypercholesterolemia

Interventions

DRUG

Results Available

NCT05944224 | RECRUITING | PHASE1/PHASE2

63 participants

A Study to Efficacy and Safety of SPH4336 Monotherapy or in Combination With Cadonilimab in Patients With Advanced Solid Tumors.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-10-17
Completion:: 2026-12-31

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT05942313 | RECRUITING

100 participants

Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-08-28
Completion:: 2026-12-01

Conditions

Opioid Use Disorder
Pregnancy Related

Interventions

DRUG

No Results Yet

NCT05908240 | ACTIVE_NOT_RECRUITING | NA

520 participants

Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-06-15
Completion:: 2026-09-30

Conditions

Psoriasis
Psoriatic Arthritis
Psoriatic Conditions
Cardiovascular Diseases

Interventions

OTHER

No Results Yet

NCT05900427 | TERMINATED | PHASE4

78 participants

Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-10-23
Completion:: 2025-10-05

Conditions

Total Shoulder Arthroplasty
Reverse Total Shoulder Arthroplasty

Interventions

DRUG

Results Available

NCT05879211 | ENROLLING_BY_INVITATION | NA

5000 participants

Goal Concordant Care Learning Laboratory

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-07-12
Completion:: 2026-12-31

Conditions

Cancer
Heart Failure
Copd
Dementia

Interventions

BEHAVIORAL

No Results Yet

NCT05874297 | RECRUITING | NA

50 participants

Online Nutrition Education to Decrease the Side Effects of Chemotherapy in Patients With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2026-07-15
Completion:: 2027-12-31

Conditions

Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT05870488 | ACTIVE_NOT_RECRUITING | PHASE4

110 participants

iFuse TORQ for the Treatment of Sacroiliac Joint Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-05-23
Completion:: 2025-04-23

Conditions

Sacroiliac Joint Dysfunction
Sacroiliac; Fusion
Sacroiliac Disorder
Sacroiliac Joint Pain

Interventions

DEVICE

No Results Yet

NCT05868265 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-06-02
Completion:: 2027-06-02

Conditions

Urothelial Carcinoma

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05867186 | RECRUITING

100 participants

Fit to Fight Childhood Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-06-20
Completion:: 2027-07-31

Conditions

Pediatric Oncology

Interventions

BEHAVIORAL

No Results Yet

NCT05850676 | COMPLETED

54 participants

Disentangling the Role of Depression in Hypersomnia

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-08-01
Completion:: 2026-08-03

Conditions

Hypersomnia

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05849064 | COMPLETED | NA

56 participants

Concussion Treatment in Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-09-07
Completion:: 2026-06-15

Conditions

Concussion, Mild

Interventions

BEHAVIORAL

No Results Yet

NCT05828823 | RECRUITING | NA

350 participants

Incremental Hemodialysis: The TwoPlus Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-02-26
Completion:: 2030-07-31

Conditions

End-Stage Kidney Disease

Interventions

DEVICE
OTHER

No Results Yet

NCT05814354 | ACTIVE_NOT_RECRUITING | PHASE3

551 participants

SHR-A1811 Versus Investigator's Chemotherapy in Recurrent/Metastatic Breast Cancer Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-06-30
Completion:: 2026-03-20

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT05812755 | RECRUITING | PHASE4

170 participants

SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-05-19
Completion:: 2028-07-31

Conditions

Endothelial Dysfunction
Vascular Diseases
Kidney Injury
Brain Disease
Vascular Inflammation

Interventions

DRUG

No Results Yet

NCT05812131 | RECRUITING | NA

248 participants

COPEWeb Training for Providers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-05-11
Completion:: 2027-01-01

Conditions

PTSD
Substance Use Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT05789251 | COMPLETED | NA

54 participants

Assess the Possibility of Diagnosing Diabetes and Rediabetes Following Oral Induced Hyperglycemia in Patients With Dunnigan's Partial Familial Lipodystrophy by Replacing 75 g of Glucose With a Standardized Carbohydrate Breakfast and Continuous Interstitial Monitoring Glucose)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-06-19
Completion:: 2026-01-01

Conditions

Lipodystrophy

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05785845 | COMPLETED | NA

17 participants

Computed Tomography-Guided Stereotactic Adaptive Radiotherapy (CT-STAR) for the Treatment of Central and Ultra-Central Early-Stage Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-04-10
Completion:: 2026-06-02

Conditions

Early Stage Non-small Cell Lung Cancer
Non-small Cell Lung Cancer

Interventions

RADIATION
DEVICE

No Results Yet

NCT05775588 | COMPLETED | NA

22 participants

Long-term Effects of Endobronchial Valve Implantation on Cardiac Function and Skeletal Muscle Function

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-03-27
Completion:: 2024-12-31

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

PROCEDURE

No Results Yet

NCT05770479 | ENROLLING_BY_INVITATION | NA

28 participants

Assessing and Improving the Durability of Compensatory Cognitive Training for Older Veterans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-07-01
Completion:: 2028-06-30

Conditions

Mild Cognitive Impairment

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05758896 | COMPLETED | PHASE2

218 participants

Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-12-27
Completion:: 2026-07-22

Conditions

Contrast Induced Acute Kidney Injury

Interventions

DRUG

No Results Yet

NCT05755061 | ACTIVE_NOT_RECRUITING | PHASE1

31 participants

WEBCAMS: Walking Exercise for Brain and Cognition in Adults With Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-02-01
Completion:: 2025-02-28

Conditions

Multiple Sclerosis
Relapsing-remitting Multiple Sclerosis

Interventions

BEHAVIORAL

No Results Yet

NCT05753501 | ACTIVE_NOT_RECRUITING | PHASE1

135 participants

Study to Evaluate Adverse Events, Change in Disease Activity, and How Oral ABBV-101 Moves Through the Body in Adult Participants With B-Cell Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-06-09
Completion:: 2031-03-31

Conditions

Hematologic Cancer

Interventions

DRUG

No Results Yet

NCT05752084 | COMPLETED

250 participants

Bilirubin Increases the Risk of Nosocomial Infection in Cirrhotic Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-01-01
Completion:: 2022-11-01

Conditions

Nosocomial Infection

No Results Yet

NCT05750862 | COMPLETED | NA

30 participants

Accuracy of Topography Guided Automatic Marking of the Intraocular Lens (IOL) -Axis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-03-20
Completion:: 2024-09-30

Conditions

Cataract Senile
Astigmatism

Interventions

PROCEDURE

No Results Yet

NCT05746546 | COMPLETED | PHASE2

25 participants

Depressed Mood Improvement Through Nicotine Dosing-3 (Depressed MIND3) Extension

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-04-15
Completion:: 2026-07-09

Conditions

Depressive Disorder

Interventions

DRUG

No Results Yet

NCT05746273 | COMPLETED | PHASE2

40 participants

Depressed Mood Improvement Through Nicotine Dosing 3

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-04-15
Completion:: 2026-07-09

Conditions

Depressive Disorder

Interventions

DRUG

No Results Yet

NCT05739162 | ACTIVE_NOT_RECRUITING | NA

2 participants

A Study of Endoscopic Sleeve Gastroplasty for Obesity in Ulcerative Colitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-09-20
Completion:: 2025-07-01

Conditions

Obesity
Ulcerative Colitis

Interventions

DEVICE
BEHAVIORAL

Results Available

NCT05732675 | COMPLETED | NA

167 participants

Skills to Empower Affirmative Men

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2021-09-01
Completion:: 2025-03-01

Conditions

Bisexuality
Homosexuality
HIV Infections

Interventions

BEHAVIORAL

Results Available

NCT05731141 | RECRUITING

1200 participants

A Prospective Natural History Study of Lymphatic Anomalies

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-03-20
Completion:: 2026-12-31

Conditions

Lymphatic Diseases
Lymphatic Abnormalities

No Results Yet