Clinical Trials

NCT06069141 | RECRUITING | NA

688 participants

Comparisons of Treatment Responses of Early Syphilis to Benzathine Penicillin G With or Without Doxycycline

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-01

Completion:

2027-12-31

Conditions

• Early Syphilis, Latent, Serological Relapse After Treatment

Interventions

• DRUG

No Results Yet

NCT06066528 | COMPLETED | PHASE3

755 participants

A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-11-27

Completion:

2025-12-12

Conditions

• Obesity
• Diabetes Mellitus, Type 2

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT06061614 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

15 participants

Safety and Efficacy Study of NGGT002 in PKU Adult Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-03-30

Completion:

2028-12-30

Conditions

• Phenylketonurias

Interventions

• GENETIC

No Results Yet

NCT06060743 | COMPLETED | NA

88 participants

Examining the Effect of Mobile Application on Insulin Use Perception and Self-Management

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-01-01

Completion:

2024-05-01

Conditions

• Type 2 Diabetes Treated With Insulin

Interventions

• OTHER

No Results Yet

NCT06056895 | ACTIVE_NOT_RECRUITING | PHASE2

12 participants

Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-11-08

Completion:

2027-01-31

Conditions

• Unresectable Clinical Stage III Merkel Cell Carcinoma AJCC v8
• Clinical Stage IV Merkel Cell Carcinoma AJCC v8
• Merkel Cell Carcinoma

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

No Results Yet

NCT06056297 | RECRUITING | PHASE3

176 participants

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-06-06

Completion:

2027-09-30

Conditions

• Neutropenia

Interventions

• DRUG

No Results Yet

NCT06041581 | ENROLLING_BY_INVITATION | NA

200 participants

SHADES Mechanistic Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-04-25

Completion:

2027-07-31

Conditions

• Insomnia
• Insomnia Chronic
• Insomnia, Primary
• Sleep Disturbance
• Sleep Disorder
• Cardiovascular Diseases
• Heart Diseases
• Coronary Artery Disease
• Stroke
• Autonomic Dysfunction
• Systemic Inflammatory Response
• Metabolic Disease

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06030128 | COMPLETED | NA

150 participants

Core Stabilization Exercise Therapy in Chronic Lower Back Back Management in Community Dwelling Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-09-15

Completion:

2025-05-01

Conditions

• Chronic Low-back Pain
• Older Adults
• Core Stabilization Exercise Therapy

Interventions

• BEHAVIORAL

No Results Yet

NCT05995821 | RECRUITING

1250 participants

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2016-08-25

Completion:

2028-08-25

Conditions

• Head and Neck Cancer
• Lung Cancer
• Gastrointestinal Cancer

Interventions

• OTHER

No Results Yet

NCT05990465 | RECRUITING | PHASE1

12 participants

LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-02-06

Completion:

2028-07-31

Conditions

• Non Hodgkin Lymphoma
• Diffuse Large B Cell Lymphoma
• Follicular Lymphoma
• Marginal Zone Lymphoma
• Mantle Cell Lymphoma
• Burkitt Lymphoma

Interventions

• DRUG

No Results Yet

NCT05988385 | RECRUITING | NA

200 participants

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-08-29

Completion:

2027-06-30

Conditions

• Obstructive Sleep Apnea
• Cognitive Decline

Interventions

• DEVICE

No Results Yet

NCT05984238 | COMPLETED | NA

33 participants

A Trial to Evaluate Safety, Feasibility and Efficacy of Endoscopic Duodenal PEF Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-03

Completion:

2025-03-21

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DEVICE
• DRUG
• OTHER

No Results Yet

NCT05952856 | COMPLETED | PHASE3

2912 participants

A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-10

Completion:

2025-07-28

Conditions

• Hypercholesterolemia
• Familial Hypercholesterolemia

Interventions

• DRUG

Results Available

NCT05944224 | RECRUITING | PHASE1/PHASE2

63 participants

A Study to Efficacy and Safety of SPH4336 Monotherapy or in Combination With Cadonilimab in Patients With Advanced Solid Tumors.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-10-17

Completion:

2026-12-31

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT05942313 | RECRUITING

100 participants

Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-28

Completion:

2026-12-01

Conditions

• Opioid Use Disorder
• Pregnancy Related

Interventions

• DRUG

No Results Yet

NCT05908240 | ACTIVE_NOT_RECRUITING | NA

520 participants

Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-15

Completion:

2026-09-30

Conditions

• Psoriasis
• Psoriatic Arthritis
• Psoriatic Conditions
• Cardiovascular Diseases

Interventions

• OTHER

No Results Yet

NCT05900427 | TERMINATED | PHASE4

78 participants

Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-10-23

Completion:

2025-10-05

Conditions

• Total Shoulder Arthroplasty
• Reverse Total Shoulder Arthroplasty

Interventions

• DRUG

Results Available

NCT05879211 | ENROLLING_BY_INVITATION | NA

5000 participants

Goal Concordant Care Learning Laboratory

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-07-12

Completion:

2026-12-31

Conditions

• Cancer
• Heart Failure
• Copd
• Dementia

Interventions

• BEHAVIORAL

No Results Yet

NCT05874297 | RECRUITING | NA

50 participants

Online Nutrition Education to Decrease the Side Effects of Chemotherapy in Patients With Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-07-15

Completion:

2027-12-31

Conditions

• Anatomic Stage I Breast Cancer AJCC v8
• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage III Breast Cancer AJCC v8

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT05870488 | ACTIVE_NOT_RECRUITING | PHASE4

110 participants

iFuse TORQ for the Treatment of Sacroiliac Joint Dysfunction

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-05-23

Completion:

2025-04-23

Conditions

• Sacroiliac Joint Dysfunction
• Sacroiliac; Fusion
• Sacroiliac Disorder
• Sacroiliac Joint Pain

Interventions

• DEVICE

No Results Yet

NCT05868265 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-02

Completion:

2027-06-02

Conditions

• Urothelial Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05867186 | RECRUITING

100 participants

Fit to Fight Childhood Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-20

Completion:

2027-07-31

Conditions

• Pediatric Oncology

Interventions

• BEHAVIORAL

No Results Yet

NCT05850676 | COMPLETED

54 participants

Disentangling the Role of Depression in Hypersomnia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-01

Completion:

2026-08-03

Conditions

• Hypersomnia

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05849064 | COMPLETED | NA

56 participants

Concussion Treatment in Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-09-07

Completion:

2026-06-15

Conditions

• Concussion, Mild

Interventions

• BEHAVIORAL

No Results Yet

NCT05828823 | RECRUITING | NA

350 participants

Incremental Hemodialysis: The TwoPlus Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2024-02-26

Completion:

2030-07-31

Conditions

• End-Stage Kidney Disease

Interventions

• DEVICE
• OTHER

No Results Yet

NCT05814354 | ACTIVE_NOT_RECRUITING | PHASE3

551 participants

SHR-A1811 Versus Investigator's Chemotherapy in Recurrent/Metastatic Breast Cancer Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-30

Completion:

2026-03-20

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05812755 | RECRUITING | PHASE4

170 participants

SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-05-19

Completion:

2028-07-31

Conditions

• Endothelial Dysfunction
• Vascular Diseases
• Kidney Injury
• Brain Disease
• Vascular Inflammation

Interventions

• DRUG

No Results Yet

NCT05812131 | RECRUITING | NA

248 participants

COPEWeb Training for Providers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2025-05-11

Completion:

2027-01-01

Conditions

• PTSD
• Substance Use Disorders

Interventions

• BEHAVIORAL

No Results Yet

NCT05789251 | COMPLETED | NA

54 participants

Assess the Possibility of Diagnosing Diabetes and Rediabetes Following Oral Induced Hyperglycemia in Patients With Dunnigan's Partial Familial Lipodystrophy by Replacing 75 g of Glucose With a Standardized Carbohydrate Breakfast and Continuous Interstitial Monitoring Glucose)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-19

Completion:

2026-01-01

Conditions

• Lipodystrophy

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05785845 | COMPLETED | NA

17 participants

Computed Tomography-Guided Stereotactic Adaptive Radiotherapy (CT-STAR) for the Treatment of Central and Ultra-Central Early-Stage Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-04-10

Completion:

2026-06-02

Conditions

• Early Stage Non-small Cell Lung Cancer
• Non-small Cell Lung Cancer

Interventions

• RADIATION
• DEVICE

No Results Yet

NCT05775588 | COMPLETED | NA

22 participants

Long-term Effects of Endobronchial Valve Implantation on Cardiac Function and Skeletal Muscle Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-03-27

Completion:

2024-12-31

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

• PROCEDURE

No Results Yet

NCT05770479 | ENROLLING_BY_INVITATION | NA

28 participants

Assessing and Improving the Durability of Compensatory Cognitive Training for Older Veterans

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-07-01

Completion:

2028-06-30

Conditions

• Mild Cognitive Impairment

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05758896 | COMPLETED | PHASE2

218 participants

Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-12-27

Completion:

2026-07-22

Conditions

• Contrast Induced Acute Kidney Injury

Interventions

• DRUG

No Results Yet

NCT05755061 | ACTIVE_NOT_RECRUITING | PHASE1

31 participants

WEBCAMS: Walking Exercise for Brain and Cognition in Adults With Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-02-01

Completion:

2025-02-28

Conditions

• Multiple Sclerosis
• Relapsing-remitting Multiple Sclerosis

Interventions

• BEHAVIORAL

No Results Yet

NCT05753501 | ACTIVE_NOT_RECRUITING | PHASE1

135 participants

Study to Evaluate Adverse Events, Change in Disease Activity, and How Oral ABBV-101 Moves Through the Body in Adult Participants With B-Cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-06-09

Completion:

2031-03-31

Conditions

• Hematologic Cancer

Interventions

• DRUG

No Results Yet

NCT05752084 | COMPLETED

250 participants

Bilirubin Increases the Risk of Nosocomial Infection in Cirrhotic Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2022-01-01

Completion:

2022-11-01

Conditions

• Nosocomial Infection

No Results Yet

NCT05750862 | COMPLETED | NA

30 participants

Accuracy of Topography Guided Automatic Marking of the Intraocular Lens (IOL) -Axis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-03-20

Completion:

2024-09-30

Conditions

• Cataract Senile
• Astigmatism

Interventions

• PROCEDURE

No Results Yet

NCT05746546 | COMPLETED | PHASE2

25 participants

Depressed Mood Improvement Through Nicotine Dosing-3 (Depressed MIND3) Extension

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-04-15

Completion:

2026-07-09

Conditions

• Depressive Disorder

Interventions

• DRUG

No Results Yet

NCT05746273 | COMPLETED | PHASE2

40 participants

Depressed Mood Improvement Through Nicotine Dosing 3

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-04-15

Completion:

2026-07-09

Conditions

• Depressive Disorder

Interventions

• DRUG

No Results Yet

NCT05739162 | ACTIVE_NOT_RECRUITING | NA

2 participants

A Study of Endoscopic Sleeve Gastroplasty for Obesity in Ulcerative Colitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-09-20

Completion:

2025-07-01

Conditions

• Obesity
• Ulcerative Colitis

Interventions

• DEVICE
• BEHAVIORAL

Results Available