Clinical Trials

NCT05524012 | ACTIVE_NOT_RECRUITING

40 participants

Longitudinal Multimodal Response Assessment During Neoadjuvant Treatment of Rectal Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-11-30
Completion:: 2026-01-31

Conditions

Locally Advanced Rectal Carcinoma
Neoadjuvant Treatment
Radiotherapy
Adaptive Treatment

Interventions

DIAGNOSTIC_TEST
DEVICE

No Results Yet

NCT05515874 | WITHDRAWN | PHASE4

0 participants

Predicting Stroke Risk in ICAD With Novel MRI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2020-09-01
Completion:: 2025-06-30

Conditions

Intracranial Atherosclerosis

Interventions

DRUG

No Results Yet

NCT05511324 | ACTIVE_NOT_RECRUITING | NA

124 participants

Simulation-Based Caregiving Skills Training for Family Members of High Grade Glioma Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-10-21
Completion:: 2026-08-31

Conditions

Glioma

Interventions

BEHAVIORAL

No Results Yet

NCT05483868 | ACTIVE_NOT_RECRUITING | PHASE1

55 participants

A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-09-26
Completion:: 2027-03-31

Conditions

Non-muscle-invasive Bladder Cancer
NMIBC
Non-Muscle Invasive Bladder Carcinoma
Non-Muscle Invasive Bladder Neoplasms
Non-Muscle Invasive Bladder Urothelial Carcinoma
Urothelial Carcinoma Bladder

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT05445830 | COMPLETED | NA

62 participants

Exercise Intolerance in Post-COVID Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-09-01
Completion:: 2023-09-15

Conditions

Post-COVID Syndrome

Interventions

PROCEDURE

No Results Yet

NCT05436756 | COMPLETED | NA

198 participants

Chronic Post-leptospirosis Manifestations in Reunion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-07-25
Completion:: 2026-04-28

Conditions

Leptospirosis

Interventions

OTHER

No Results Yet

NCT05401110 | RECRUITING | PHASE1

60 participants

Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-09-15
Completion:: 2028-01-31

Conditions

Non Small Cell Lung Cancer
Lung Cancer

Interventions

DRUG

No Results Yet

NCT05400382 | RECRUITING | NA

75 participants

Maternal Mindfulness: Depression and Postpartum Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-01
Completion:: 2028-03-31

Conditions

Depression, Unipolar
Pain, Postoperative

Interventions

BEHAVIORAL

No Results Yet

NCT05398185 | ACTIVE_NOT_RECRUITING | NA

241 participants

WiseApp for Spanish Speakers Living With HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-03-01
Completion:: 2026-11-01

Conditions

HIV Infections
Acquired Immune Deficiency Syndrome
Sexually Transmitted Diseases, Viral

Interventions

DEVICE

No Results Yet

NCT05397691 | ACTIVE_NOT_RECRUITING | NA

80 participants

Substance Use Prevention for Youth With Parents in Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-08-29
Completion:: 2026-07-31

Conditions

Substance Use Disorders

Interventions

OTHER

No Results Yet

NCT05390567 | RECRUITING

800 participants

Project CONTINUITY: Promoting Evidence-Based Cancer Screening Among Underserved Women

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-06-07
Completion:: 2027-05-01

Conditions

Cervical Cancer Screening Methods

Interventions

BEHAVIORAL

No Results Yet

NCT05386108 | RECRUITING | PHASE1/PHASE2

73 participants

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-08-31
Completion:: 2026-12-31

Conditions

Breast Neoplasms
Brain Neoplasms
Neoplasms by Site
Neoplasms
Breast Diseases
Central Nervous System Neoplasms
Brain Diseases
Central Nervous System Diseases

Interventions

DRUG

No Results Yet

NCT05375812 | RECRUITING

85 participants

NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-04-16
Completion:: 2030-12-31

Conditions

Gulf War Illness

No Results Yet

NCT05374824 | RECRUITING

4680 participants

Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-04-01
Completion:: 2026-12-31

Conditions

Lennox Gastaut Syndrome

No Results Yet

NCT05372614 | RECRUITING | PHASE1

58 participants

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-10-05
Completion:: 2028-07-17

Conditions

Metastatic Malignant Solid Neoplasm
Metastatic Pancreatic Adenocarcinoma
Stage III Pancreatic Cancer AJCC v8
Stage IV Pancreatic Cancer AJCC v8
Unresectable Malignant Solid Neoplasm
Unresectable Pancreatic Adenocarcinoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT05368493 | ENROLLING_BY_INVITATION | NA

182 participants

Air Pollution and Development in the Boricua Youth Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-01-23
Completion:: 2028-06-01

Conditions

Pollution; Exposure
Neurodevelopmental Disorders

Interventions

OTHER

No Results Yet

NCT05353192 | COMPLETED | PHASE4

39 participants

A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone in Children With Achondroplasia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-08-20
Completion:: 2025-08-25

Conditions

Achondroplasia

Interventions

DRUG

No Results Yet

NCT05325931 | COMPLETED | NA

30 participants

1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-02-25
Completion:: 2022-03-28

Conditions

Presbyopia

Interventions

DEVICE

Results Available

NCT05313529 | COMPLETED | NA

396 participants

LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-10-08
Completion:: 2025-12-31

Conditions

Type 2 Diabetes Mellitus
Mild Cognitive Impairment

Interventions

DRUG

No Results Yet

NCT05304416 | ACTIVE_NOT_RECRUITING

347 participants

Clinical Markers of Dysphagia in Cardiac Surgical Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-06-07
Completion:: 2026-07-31

Conditions

Cardiovascular Diseases
Dysphagia

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT05276739 | COMPLETED | NA

47 participants

Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-07-29
Completion:: 2026-07-31

Conditions

Light Exposure
Meal Timing

Interventions

BEHAVIORAL

No Results Yet

NCT05261399 | ACTIVE_NOT_RECRUITING | PHASE3

341 participants

Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-08-03
Completion:: 2026-07-06

Conditions

Carcinoma
Non-Small-Cell Lung

Interventions

DRUG

No Results Yet

NCT05232916 | RECRUITING | PHASE3

2250 participants

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-12-16
Completion:: 2031-12-31

Conditions

Breast Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT05226507 | TERMINATED | PHASE1

45 participants

A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2021-12-31
Completion:: 2025-01-01

Conditions

Advanced Solid Tumor
Ovarian Cancer
Ovarian Clear Cell Carcinoma
Ovarian Clear Cell Tumor
Ovarian Clear Cell Adenocarcinoma
Ovarian Endometrioid Adenocarcinoma
Ovarian Endometrioid Tumor
ARID1A Gene Mutation

Interventions

DRUG

No Results Yet

NCT05210374 | RECRUITING | PHASE1

24 participants

Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-03-09
Completion:: 2026-09-01

Conditions

Relapsed Sarcomas

Interventions

DRUG

No Results Yet

NCT05207059 | ACTIVE_NOT_RECRUITING | NA

500 participants

Healthy Early Life Moments in Singapore

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-03-18
Completion:: 2027-12-31

Conditions

Metabolic Disease
Mental Health Wellness 1
Lifestyle Risk Reduction
Maternal Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT05176808 | COMPLETED | NA

117 participants

Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-02-07
Completion:: 2026-04-10

Conditions

Autism Spectrum Disorder
Autistic Disorder
Active Autistic Disorder
Autism
Asperger Syndrome
PDD-NOS
Social Communication Delay
Mixed Expressive Receptive Language Disorder
Other Symbolic Dysfunctions

Interventions

BEHAVIORAL

No Results Yet

NCT05172934 | COMPLETED | PHASE2

20 participants

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy Pilot Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-04-11
Completion:: 2023-09-12

Conditions

Ischemic Stroke

Interventions

DRUG

Results Available

NCT05107115 | COMPLETED | PHASE2

160 participants

Rilzabrutinib for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2021-11-24
Completion:: 2023-07-19

Conditions

Chronic Spontaneous Urticaria

Interventions

DRUG

Results Available

NCT05093634 | COMPLETED | PHASE3

296 participants

EMANATE: A Study of Setmelanotide in Patients With Specific Gene Variants in the MC4R Pathway

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2021-12-10
Completion:: 2025-12-22

Conditions

Obesity
Genetic Obesity

Interventions

DRUG

No Results Yet

NCT05090267 | RECRUITING | NA

80 participants

The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-06-01
Completion:: 2026-12-30

Conditions

Cognition
Gut Microbiome

Interventions

DIETARY_SUPPLEMENT
DEVICE

No Results Yet

NCT05086497 | RECRUITING | NA

155 participants

WBSI Guided Personalized Delivery of TTFields

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-01-15
Completion:: 2027-06-30

Conditions

GBM
Glioma Glioblastoma Multiforme
Tumor, Brain

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05081037 | ACTIVE_NOT_RECRUITING | NA

208 participants

Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2021-09-06
Completion:: 2028-07-15

Conditions

Gestational Diabetes
Glucose Metabolism Disorders
Metabolic Disease

Interventions

DEVICE

No Results Yet

NCT05066542 | ACTIVE_NOT_RECRUITING | NA

60 participants

Recreational Basketball to Increase Participation in Diabetes Prevention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2021-06-11
Completion:: 2023-11-30

Conditions

Type 2 Diabetes
PreDiabetes

Interventions

BEHAVIORAL

No Results Yet

NCT05064709 | RECRUITING | NA

1500 participants

Assessment of CCM in HF With Higher Ejection Fraction

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-02-03
Completion:: 2029-02-01

Conditions

Heart Failure
Heart Failure With Preserved Ejection Fraction
Heart Failure With Mid Range Ejection Fraction
Heart Failure With Moderately Reduced Ejection Fraction
Diastolic Heart Failure

Interventions

DEVICE

No Results Yet

NCT05055050 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

A Window of Opportunity Phase I Study of UGN-201 in Patients With Bladder Cancer Undergoing Radical Cystectomy Protocol #: 2021-0630

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-01-24
Completion:: 2026-08-31

Conditions

Bladder Cancer
Bladder

Interventions

DRUG

No Results Yet

NCT05039840 | ACTIVE_NOT_RECRUITING | PHASE2

109 participants

Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2021-11-10
Completion:: 2026-09-03

Conditions

Systemic Lupus Erythematosus

Interventions

DRUG

No Results Yet

NCT05028621 | SUSPENDED | NA

135 participants

Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms and Castleman Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2021-06-18
Completion:: 2026-09-30

Conditions

Castleman's Disease (CD)
Langerhans Cell Histiocytosis (LCH)
Non-Langerhans-Cell Histiocytosis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05017740 | ACTIVE_NOT_RECRUITING | NA

47 participants

PICSI RCT in Couples With a Previous Poor Fertilisation Cycle in IVF

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-03-15
Completion:: 2026-12-31

Conditions

Infertility
IVF

Interventions

PROCEDURE

No Results Yet

NCT05002478 | RECRUITING | NA

14 participants

Infants With Severe Acute Respiratory Distress Syndrome: The Prone Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-07-30
Completion:: 2027-07-31

Conditions

Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Surfactant Dysfunction
Infant

Interventions

OTHER

No Results Yet