Clinical Trials

NCT05627674 | ENROLLING_BY_INVITATION | NA

915 participants

Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-01-01
Completion:: 2027-08-31

Conditions

Smoking
Smoking Cessation
Tobacco Use Cessation

Interventions

BEHAVIORAL

No Results Yet

NCT05619913 | COMPLETED | PHASE2

13 participants

EPOCH: Eribulin and Pembrolizumab in Ovarian/Uterine Carcinosarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-05-22
Completion:: 2025-03-31

Conditions

Ovarian Carcinosarcoma
Uterine Carcinosarcoma

Interventions

DRUG

No Results Yet

NCT05610852 | RECRUITING | NA

276 participants

Single-Port Transvesical Partial Prostatectomy Versus High Intensity Focused Ultrasound

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-01-01
Completion:: 2026-12-01

Conditions

Prostate Adenocarcinoma
Prostate Cancer

Interventions

PROCEDURE

No Results Yet

NCT05600933 | ENROLLING_BY_INVITATION

1200 participants

Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-05-15
Completion:: 2033-06-15

Conditions

Solid Tumors
Hematologic Malignancy
Gastrointestinal Cancer
Liver Cancer
Pancreatic Cancer
Melanoma
Pre-Malignancy
Lung Cancer

No Results Yet

NCT05591768 | COMPLETED | NA

90 participants

Monopolar Versus Biopolar Radiofrequency in OA Knee Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-11-14
Completion:: 2024-02-01

Conditions

Osteoarthritis, Knee

Interventions

PROCEDURE

No Results Yet

NCT05581004 | ACTIVE_NOT_RECRUITING | PHASE1

165 participants

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-10-20
Completion:: 2028-07-31

Conditions

Locally Advanced or Metastatic Solid Tumors
NSCLC
HNSCC
Melanoma
TNBC
Esophageal Cancer
Gastric Cancer
Cervical Cancer
Colorectal Cancer
Urothelial Carcinoma
Clear Cell RCC
HCC

Interventions

DRUG

No Results Yet

NCT05565118 | RECRUITING | PHASE1

10 participants

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-04-09
Completion:: 2026-12-31

Conditions

High Grade Glioma
Glioblastoma

Interventions

PROCEDURE

No Results Yet

NCT05553912 | COMPLETED | NA

154 participants

QBSafe: a Randomized Trial of a Novel Intervention to Improve Care for People Living With Type 2 Diabetes.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-11-02
Completion:: 2025-02-24

Conditions

Type2Diabetes
Diabetes

Interventions

BEHAVIORAL

Results Available

NCT05551754 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

10 participants

Acute Effects of Ketone Supplement on Responses to Alcohol Challenge in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-10-20
Completion:: 2026-12-31

Conditions

Alcohol Drinking

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT05546866 | ACTIVE_NOT_RECRUITING | PHASE2

51 participants

Study to Assess the Efficacy and Safety of Adjuvant Osimertinib in NSCLC With Uncommon EGFRm

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-02-09
Completion:: 2029-06-30

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05543616 | COMPLETED | PHASE3

4338 participants

A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-09-23
Completion:: 2026-07-10

Conditions

SARS-CoV-2 Virus
Severe Acute Respiratory Syndrome Coronavirus 2
COVID-19

Interventions

BIOLOGICAL

No Results Yet

NCT05535244 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

90 participants

A Study Evaluating the Efficacy and Safety of Cevostamab in Prior B Cell Maturation Antigen (BCMA)-Exposed Participants With Relapsed/Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-10-17
Completion:: 2027-02-26

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05528172 | COMPLETED | PHASE3

330 participants

A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-08-04
Completion:: 2023-06-22

Conditions

Corneal Edema After Cataract Surgery

Interventions

DRUG

Results Available

NCT05524012 | ACTIVE_NOT_RECRUITING

40 participants

Longitudinal Multimodal Response Assessment During Neoadjuvant Treatment of Rectal Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-11-30
Completion:: 2026-01-31

Conditions

Locally Advanced Rectal Carcinoma
Neoadjuvant Treatment
Radiotherapy
Adaptive Treatment

Interventions

DIAGNOSTIC_TEST
DEVICE

No Results Yet

NCT05515874 | WITHDRAWN | PHASE4

0 participants

Predicting Stroke Risk in ICAD With Novel MRI

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2020-09-01
Completion:: 2025-06-30

Conditions

Intracranial Atherosclerosis

Interventions

DRUG

No Results Yet

NCT05511324 | ACTIVE_NOT_RECRUITING | NA

124 participants

Simulation-Based Caregiving Skills Training for Family Members of High Grade Glioma Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-10-21
Completion:: 2026-08-31

Conditions

Glioma

Interventions

BEHAVIORAL

No Results Yet

NCT05483868 | ACTIVE_NOT_RECRUITING | PHASE1

55 participants

A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-09-26
Completion:: 2027-03-31

Conditions

Non-muscle-invasive Bladder Cancer
NMIBC
Non-Muscle Invasive Bladder Carcinoma
Non-Muscle Invasive Bladder Neoplasms
Non-Muscle Invasive Bladder Urothelial Carcinoma
Urothelial Carcinoma Bladder

Interventions

DRUG
COMBINATION_PRODUCT

No Results Yet

NCT05445830 | COMPLETED | NA

62 participants

Exercise Intolerance in Post-COVID Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-09-01
Completion:: 2023-09-15

Conditions

Post-COVID Syndrome

Interventions

PROCEDURE

No Results Yet

NCT05436756 | COMPLETED | NA

198 participants

Chronic Post-leptospirosis Manifestations in Reunion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-07-25
Completion:: 2026-04-28

Conditions

Leptospirosis

Interventions

OTHER

No Results Yet

NCT05401110 | RECRUITING | PHASE1

60 participants

Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-09-15
Completion:: 2028-01-31

Conditions

Non Small Cell Lung Cancer
Lung Cancer

Interventions

DRUG

No Results Yet

NCT05400382 | RECRUITING | NA

75 participants

Maternal Mindfulness: Depression and Postpartum Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2025-12-01
Completion:: 2028-03-31

Conditions

Depression, Unipolar
Pain, Postoperative

Interventions

BEHAVIORAL

No Results Yet

NCT05398185 | ACTIVE_NOT_RECRUITING | NA

241 participants

WiseApp for Spanish Speakers Living With HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-03-01
Completion:: 2026-11-01

Conditions

HIV Infections
Acquired Immune Deficiency Syndrome
Sexually Transmitted Diseases, Viral

Interventions

DEVICE

No Results Yet

NCT05397691 | ACTIVE_NOT_RECRUITING | NA

80 participants

Substance Use Prevention for Youth With Parents in Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-08-29
Completion:: 2026-07-31

Conditions

Substance Use Disorders

Interventions

OTHER

No Results Yet

NCT05390567 | RECRUITING

800 participants

Project CONTINUITY: Promoting Evidence-Based Cancer Screening Among Underserved Women

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2024-06-07
Completion:: 2027-05-01

Conditions

Cervical Cancer Screening Methods

Interventions

BEHAVIORAL

No Results Yet

NCT05386108 | RECRUITING | PHASE1/PHASE2

73 participants

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-08-31
Completion:: 2026-12-31

Conditions

Breast Neoplasms
Brain Neoplasms
Neoplasms by Site
Neoplasms
Breast Diseases
Central Nervous System Neoplasms
Brain Diseases
Central Nervous System Diseases

Interventions

DRUG

No Results Yet

NCT05375812 | RECRUITING

85 participants

NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-04-16
Completion:: 2030-12-31

Conditions

Gulf War Illness

No Results Yet

NCT05374824 | RECRUITING

4680 participants

Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-04-01
Completion:: 2026-12-31

Conditions

Lennox Gastaut Syndrome

No Results Yet

NCT05372614 | RECRUITING | PHASE1

58 participants

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-10-05
Completion:: 2028-07-17

Conditions

Metastatic Malignant Solid Neoplasm
Metastatic Pancreatic Adenocarcinoma
Stage III Pancreatic Cancer AJCC v8
Stage IV Pancreatic Cancer AJCC v8
Unresectable Malignant Solid Neoplasm
Unresectable Pancreatic Adenocarcinoma

Interventions

PROCEDURE
DRUG
BIOLOGICAL

No Results Yet

NCT05368493 | ENROLLING_BY_INVITATION | NA

182 participants

Air Pollution and Development in the Boricua Youth Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-01-23
Completion:: 2028-06-01

Conditions

Pollution; Exposure
Neurodevelopmental Disorders

Interventions

OTHER

No Results Yet

NCT05353192 | COMPLETED | PHASE4

39 participants

A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone in Children With Achondroplasia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-08-20
Completion:: 2025-08-25

Conditions

Achondroplasia

Interventions

DRUG

No Results Yet

NCT05325931 | COMPLETED | NA

30 participants

1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-02-25
Completion:: 2022-03-28

Conditions

Presbyopia

Interventions

DEVICE

Results Available

NCT05313529 | COMPLETED | NA

396 participants

LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-10-08
Completion:: 2025-12-31

Conditions

Type 2 Diabetes Mellitus
Mild Cognitive Impairment

Interventions

DRUG

No Results Yet

NCT05304416 | ACTIVE_NOT_RECRUITING

347 participants

Clinical Markers of Dysphagia in Cardiac Surgical Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-06-07
Completion:: 2026-07-31

Conditions

Cardiovascular Diseases
Dysphagia

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT05276739 | COMPLETED | NA

47 participants

Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-07-29
Completion:: 2026-07-31

Conditions

Light Exposure
Meal Timing

Interventions

BEHAVIORAL

No Results Yet

NCT05261399 | ACTIVE_NOT_RECRUITING | PHASE3

341 participants

Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-08-03
Completion:: 2026-07-06

Conditions

Carcinoma
Non-Small-Cell Lung

Interventions

DRUG

No Results Yet

NCT05232916 | RECRUITING | PHASE3

2250 participants

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-12-16
Completion:: 2031-12-31

Conditions

Breast Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT05226507 | TERMINATED | PHASE1

45 participants

A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2021-12-31
Completion:: 2025-01-01

Conditions

Advanced Solid Tumor
Ovarian Cancer
Ovarian Clear Cell Carcinoma
Ovarian Clear Cell Tumor
Ovarian Clear Cell Adenocarcinoma
Ovarian Endometrioid Adenocarcinoma
Ovarian Endometrioid Tumor
ARID1A Gene Mutation

Interventions

DRUG

No Results Yet

NCT05210374 | RECRUITING | PHASE1

24 participants

Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2023-03-09
Completion:: 2026-09-01

Conditions

Relapsed Sarcomas

Interventions

DRUG

No Results Yet

NCT05207059 | ACTIVE_NOT_RECRUITING | NA

500 participants

Healthy Early Life Moments in Singapore

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-03-18
Completion:: 2027-12-31

Conditions

Metabolic Disease
Mental Health Wellness 1
Lifestyle Risk Reduction
Maternal Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT05176808 | COMPLETED | NA

117 participants

Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-06
Start Date:: 2022-02-07
Completion:: 2026-04-10

Conditions

Autism Spectrum Disorder
Autistic Disorder
Active Autistic Disorder
Autism
Asperger Syndrome
PDD-NOS
Social Communication Delay
Mixed Expressive Receptive Language Disorder
Other Symbolic Dysfunctions

Interventions

BEHAVIORAL

No Results Yet