Clinical Trials

NCT04298723 | RECRUITING | NA

530 participants

Comparison of LAA-Closure vs Oral Anticoagulation in Patients With NVAF and Status Post Intracranial Bleeding.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-06-16

Completion:

2029-06-30

Conditions

• Intracranial Hemorrhages
• Atrial Fibrillation (AF)
• Atrial Flutter

Interventions

• DEVICE

No Results Yet

NCT04289324 | COMPLETED | NA

36 participants

Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Preterm Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-02-25

Completion:

2025-08-31

Conditions

• High Frequency Oscillation Ventilation
• Extreme Prematurity
• Lung Injury, Acute

Interventions

• PROCEDURE

No Results Yet

NCT04246788 | COMPLETED | NA

40 participants

Intensive Robotic Rehabilitation in Children With Hemiparesia Using GEOSYSTEM

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-07-17

Completion:

2021-11-24

Conditions

• Infantile Hemiplegia

Interventions

• OTHER

No Results Yet

NCT04224987 | COMPLETED | PHASE4

864493 participants

Azithromycin for Child Survival in Niger: Mortality and Resistance Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-11-24

Completion:

2024-07-31

Conditions

• Mortality
• Resistance Bacterial
• Child, Only

Interventions

• DRUG
• OTHER

Results Available

NCT04221438 | TERMINATED | PHASE2

3 participants

Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2021-09-22

Completion:

2024-06-10

Conditions

• Melanoma of Unknown Primary
• Metastatic Malignant Neoplasm in Lymph Node
• Pathologic Stage IIIB Cutaneous Melanoma AJCC v8
• Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
• Pathologic Stage IIID Cutaneous Melanoma AJCC v8
• Recurrent Cutaneous Melanoma

Interventions

• DRUG
• PROCEDURE
• OTHER

Results Available

NCT04218617 | RECRUITING | PHASE2

130 participants

Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-02-07

Completion:

2026-10-31

Conditions

• Spine Metastases
• Spine Stereotactic Radiosurgery (sSRS)

Interventions

• DEVICE
• OTHER
• RADIATION

No Results Yet

NCT04193878 | TERMINATED | PHASE3

465 participants

ARrest RESpiraTory Failure From PNEUMONIA

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-06-01

Completion:

2025-07-22

Conditions

• Pneumonia
• Hypoxemia
• Acute Respiratory Failure
• COVID-19 Pneumonia

Interventions

• DRUG

Results Available

NCT04179643 | COMPLETED | PHASE1

11 participants

AB-1002 in Patients With Class III Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-11-20

Completion:

2024-08-20

Conditions

• Congestive Heart Failure
• Heart Failure
• Heart Disease, Ischemic
• Cardiovascular Diseases
• Heart Failure, Systolic
• Heart Failure，Congestive
• Heart Arrhythmia
• Heart Failure, Diastolic
• Heart; Complications

Interventions

• BIOLOGICAL

No Results Yet

NCT04165694 | COMPLETED | NA

54 participants

Single Anastomosis Duodenal Ileal Bypass (SADI) for Sleeve Revision

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-10-15

Completion:

2025-05-01

Conditions

• Bariatric Surgery Candidate
• Severe Obesity

Interventions

• PROCEDURE

No Results Yet

NCT04151940 | RECRUITING | NA

80 participants

PET/CT Changes During Chemoimmunotherapy and Radiation Therapy in Patients With Stage IV Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-09-26

Completion:

2027-11-30

Conditions

• Metastatic Lung Non-Small Cell Carcinoma
• Recurrent Lung Non-Small Cell Carcinoma
• Stage IV Lung Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL
• RADIATION

No Results Yet

NCT04150939 | ACTIVE_NOT_RECRUITING | NA

15 participants

Cryoablation for the Treatment of Metastatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-12-23

Completion:

2028-08-31

Conditions

• Metastatic Malignant Neoplasm

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04122976 | ACTIVE_NOT_RECRUITING

805 participants

A Study in Which Non-metastatic Castration-resistant Prostate Cancer (nmCRPC) Patients for Whom a Decision to Treat With Darolutamide Has Been Made Before Enrollment Are Observed and Certain Outcomes Are Described

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2020-01-30

Completion:

2026-07-20

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT04114903 | COMPLETED

233 participants

Exploring the Anti-inflammatory Properties of Cannabis and Their Relevance to Insulin Sensitivity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2019-11-08

Completion:

2024-12-01

Conditions

• Type 2 Diabetes
• Obesity
• Cannabis Use
• Insulin Sensitivity

Interventions

• OTHER

Results Available

NCT04106713 | RECRUITING | NA

250 participants

Understanding the Person, Exploring Change Across Psychotherapies

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-10-04

Completion:

2026-09-30

Conditions

• Depression
• Anxiety Disorders

Interventions

• BEHAVIORAL

No Results Yet

NCT04104139 | COMPLETED | PHASE1

19 participants

TAS-102 With Concurrent Radiation for the Treatment of Untreated Resectable Stage II-III Rectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-12-11

Completion:

2024-09-25

Conditions

• Rectal Adenocarcinoma
• Stage IIA Rectal Cancer AJCC v8
• Stage IIB Rectal Cancer AJCC v8
• Stage III Rectal Cancer AJCC v8
• Stage IIIA Rectal Cancer AJCC v8
• Stage IIIB Rectal Cancer AJCC v8
• Stage IIIC Rectal Cancer AJCC v8

Interventions

• RADIATION
• DRUG

No Results Yet

NCT04098874 | COMPLETED | PHASE4

161 participants

Bupropion for the Prevention of Postpartum Smoking Relapse

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-01-01

Completion:

2026-07-31

Conditions

• Postpartum Smoking Relapse

Interventions

• DRUG

No Results Yet

NCT04092010 | ACTIVE_NOT_RECRUITING | NA

388 participants

Improving Preschool Outcomes by Addressing Maternal Depression in Head Start

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-08-16

Completion:

2028-04-30

Conditions

• Maternal Depression

Interventions

• BEHAVIORAL

No Results Yet

NCT04090619 | ACTIVE_NOT_RECRUITING

192 participants

Frequency of Cachexia in Ambulatory Cancer Patients and Psychological Burden in Patients and Their Primary Caregivers

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2021-06-22

Completion:

2027-12-31

Conditions

• Advanced Malignant Solid Neoplasm
• Caregiver
• Metastatic Malignant Solid Neoplasm
• Recurrent Leukemia
• Recurrent Lymphoma
• Recurrent Malignant Solid Neoplasm
• Recurrent Plasma Cell Myeloma

Interventions

• OTHER

No Results Yet

NCT04089358 | ACTIVE_NOT_RECRUITING | PHASE3

387 participants

Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2020-12-07

Completion:

2025-12-31

Conditions

• Hematopoietic and Lymphoid Cell Neoplasm
• Malignant Solid Neoplasm

Interventions

• OTHER
• DEVICE
• BEHAVIORAL

No Results Yet

NCT04077307 | RECRUITING | PHASE1

50 participants

A Study in Leukemia Patients With Karonudib

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-12-03

Completion:

2027-04-30

Conditions

• Leukemia

Interventions

• DRUG

No Results Yet

NCT04061603 | COMPLETED | NA

215 participants

iCLAS™ for Persistent Atrial Fibrillation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-12-09

Completion:

2023-08-30

Conditions

• Persistent Atrial Fibrillation

Interventions

• DEVICE

Results Available

NCT04025918 | COMPLETED | PHASE2/PHASE3

216 participants

Closed-loop Double-vasopressor Automated System to Treat Hypotension During Spinal Anaesthesia for Caesarean Section

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2011-10-31

Completion:

2012-07-31

Conditions

• Hypotension

Interventions

• DEVICE
• DRUG

No Results Yet

NCT03992417 | ACTIVE_NOT_RECRUITING

955 participants

Observational Study of Patients Receiving Dupixent® for Atopic Dermatitis (AD)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2019-06-11

Completion:

2027-03-31

Conditions

• Dermatitis Atopic

Interventions

• DRUG

No Results Yet

NCT03991130 | TERMINATED | PHASE2

6 participants

High Dose IL-2 in Combination With Anti-PD-1

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-07-17

Completion:

2023-02-07

Conditions

• Melanoma
• Renal Cell Carcinoma, Metastatic

Interventions

• DRUG

Results Available

NCT03924050 | COMPLETED | PHASE3

440 participants

Toripalimab Plus Pemetrexed+Platinus in Advanced Non-small-cell Lungcancer Patients Previsouly Treated EGFR-TKI

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-05-06

Completion:

2024-10-21

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT03915223 | COMPLETED | NA

104 participants

Soft Part Management for Surgical Fractures of the Lower Limb

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-05-10

Completion:

2023-12-25

Conditions

• Leg Injuries
• Fracture
• Edema

Interventions

• PROCEDURE

No Results Yet

NCT03904888 | RECRUITING | NA

200 participants

Conventional Versus Robot Assisted Laparoscopic Inguinal Hernia Repair

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-09-23

Completion:

2028-12-31

Conditions

• Inguinal Hernia

Interventions

• PROCEDURE

No Results Yet

NCT03897361 | COMPLETED | PHASE1/PHASE2

7 participants

Stem Cell Gene Therapy for Cystinosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-07-08

Completion:

2024-09-18

Conditions

• Lysosomal Storage Diseases
• Cystinosis

Interventions

• GENETIC

Results Available

NCT03890614 | ACTIVE_NOT_RECRUITING

70 participants

Novel 3D Hematological Malignancy Organoid to Study Disease Biology and Chemosensitivity

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2019-05-16

Completion:

2027-02-28

Conditions

• Hematologic Malignancy

Interventions

• OTHER

No Results Yet

NCT03862430 | ACTIVE_NOT_RECRUITING | PHASE2

87 participants

A Study of NanO2™ Combined With Radiation and Temozolomide in Patients With Newly Diagnosed GBM

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2023-03-31

Completion:

2027-06-30

Conditions

• Glioblastoma Multiforme

Interventions

• DRUG

No Results Yet

NCT03847467 | COMPLETED | PHASE1/PHASE2

128 participants

Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-09-20

Completion:

2026-03-06

Conditions

• Inflammatory Bowel Diseases
• Crohn Disease
• Ulcerative Colitis

Interventions

• DRUG
• OTHER

No Results Yet

NCT03776253 | COMPLETED | NA

39 participants

Conquer Fear SUPPORT Intervention in Supporting Patients With Stage III-IV Lung or Gynecologic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2018-11-15

Completion:

2024-07-26

Conditions

• Advanced Lung Carcinoma
• Malignant Female Reproductive System Neoplasm
• Stage III Lung Cancer AJCC v8
• Stage IIIA Lung Cancer AJCC v8
• Stage IIIB Lung Cancer AJCC v8
• Stage IIIC Lung Cancer AJCC v8
• Stage IV Lung Cancer AJCC v8

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT03743558 | TERMINATED | NA

56 participants

Screening of Obstructive Sleep Apnea by Smartphone Homemade Video in Childood Snoring Population

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2019-02-13

Completion:

2022-05-11

Conditions

• Obstructive Sleep Apnea Syndrome
• Adeno-amygdala Hypertrophy
• Snoring

Interventions

• BEHAVIORAL

No Results Yet

NCT03706690 | ACTIVE_NOT_RECRUITING | PHASE3

407 participants

A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2018-11-27

Completion:

2024-06-23

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• OTHER
• DRUG

Results Available

NCT03705598 | NOT_YET_RECRUITING | NA

266 participants

Tai Chi Intervention for Geriatric Pain Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2026-09-01

Completion:

2030-04-30

Conditions

• Chronic Pain
• Falls

Interventions

• BEHAVIORAL

No Results Yet

NCT03656835 | ACTIVE_NOT_RECRUITING | NA

73 participants

Nanochip Technology in Monitoring Treatment Response and Detecting Relapse in Participants With Diffuse Large B-Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2018-09-26

Completion:

2024-11-20

Conditions

• Diffuse Large B-Cell Lymphoma
• Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
• Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
• High Grade B-Cell Lymphoma

Interventions

• PROCEDURE

No Results Yet

NCT03600779 | RECRUITING | NA

85 participants

Application of ihMT MRI in Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2018-06-14

Completion:

2027-08-14

Conditions

• Sclerosis, Multiple

Interventions

• DEVICE

No Results Yet

NCT03463460 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2018-06-19

Completion:

2026-07-17

Conditions

• Thymic Carcinoma

Interventions

• OTHER
• BIOLOGICAL
• DRUG

No Results Yet

NCT03419234 | ACTIVE_NOT_RECRUITING | PHASE2

223 participants

Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2018-04-26

Completion:

2024-01-08

Conditions

• Castration Levels of Testosterone
• Castration-Resistant Prostate Carcinoma
• Metastatic Prostate Carcinoma in the Soft Tissue
• Prostate Carcinoma Metastatic in the Bone
• Stage IV Prostate Adenocarcinoma AJCC v7

Interventions

• DRUG

Results Available

NCT03392415 | ACTIVE_NOT_RECRUITING | NA

2000 participants

The NOrdic-Baltic Randomized Registry Study for Evaluation of PCI in Chronic Total Coronary Occlusion

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2018-06-01

Completion:

2025-10-01

Conditions

• Chronic Total Occlusion of Coronary Artery
• Heart Failure
• Angina Pectoris

Interventions

• PROCEDURE

No Results Yet