Clinical Trials

NCT02561234 | COMPLETED | PHASE1

76 participants

A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2015-10-22

Completion:

2019-05-28

Conditions

• Advanced Cancers

Interventions

• DRUG

No Results Yet

NCT02542293 | ACTIVE_NOT_RECRUITING | PHASE3

953 participants

Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2015-11-03

Completion:

2020-09-21

Conditions

• Non Small Cell Lung Carcinoma NSCLC

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT02531256 | COMPLETED | NA

40 participants

An Investigation of a New Laryngeal Mask Airway LMA Protector

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2014-01-31

Completion:

2015-10-31

Conditions

• Airway Morbidity

Interventions

• DEVICE

No Results Yet

NCT02489084 | COMPLETED

2000 participants

Predictive Models for Radiation-induced Side Effects in Head and Neck Cancer Based on Single Nucleotide Polymorphisms (SNP)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2013-09-30

Completion:

2026-01-31

Conditions

• Head and Neck Cancer

Interventions

• OTHER

No Results Yet

NCT02461459 | ACTIVE_NOT_RECRUITING

205 participants

Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2015-05-31

Completion:

2025-12-31

Conditions

• Tuberous Sclerosis
• Autism Disorder
• Intellectual Disability

No Results Yet

NCT02461446 | ACTIVE_NOT_RECRUITING

180 participants

Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2015-05-31

Completion:

2025-12-31

Conditions

• PTEN
• ASD
• Autism
• Macrocephaly
• PTEN Hamartoma Tumor Syndrome

No Results Yet

NCT02461420 | ACTIVE_NOT_RECRUITING

207 participants

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2015-05-31

Completion:

2025-12-31

Conditions

• Phelan-McDermid Syndrome
• Autism Spectrum Disorder
• Intellectual Disability

No Results Yet

NCT02453282 | ACTIVE_NOT_RECRUITING | PHASE3

1118 participants

Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2015-07-21

Completion:

2018-10-04

Conditions

• Non-Small-Cell Lung Carcinoma NSCLC

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT02373696 | COMPLETED

178 participants

Chronic Pain Dynamic Psychophysical Tests and Genetic Screening

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2010-04-30

Completion:

2015-01-31

Conditions

• Pain

No Results Yet

NCT02314078 | COMPLETED

390 participants

Audit of the Response Time of the Anaesthetic and Surgical Techniques for Crash Caesarean Section

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2010-01-31

Completion:

2013-12-31

Conditions

• Pregnancy
• Anaesthesia

No Results Yet

NCT02313571 | COMPLETED

350 participants

Breakthrough Pain Computer Integrated Patient Controlled Epidural Analgesia

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2010-03-31

Completion:

2015-06-30

Conditions

• Pain

No Results Yet

NCT02311933 | ACTIVE_NOT_RECRUITING | PHASE2

81 participants

Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2015-05-28

Completion:

2020-11-06

Conditions

• Recurrent Breast Carcinoma
• Stage III Breast Cancer AJCC v7
• Stage IIIA Breast Cancer AJCC v7
• Stage IIIB Breast Cancer AJCC v7
• Stage IIIC Breast Cancer AJCC v7
• Stage IV Breast Cancer AJCC v6 and v7

Interventions

• DRUG
• OTHER

Results Available

NCT02277678 | COMPLETED | PHASE3

100 participants

Comparison of Epidural Oxycodone and Epidural Morphine

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2013-08-31

Completion:

2014-12-31

Conditions

• Pruritus

Interventions

• DRUG

No Results Yet

NCT02200744 | COMPLETED

248 participants

Incidence of Recall After Procedural Sedation With Propofol in the Emergency Department

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2014-07-30

Completion:

2018-09-20

Conditions

• Fractures Reduction
• Joint Dislocation Reduction

No Results Yet

NCT02160483 | WITHDRAWN | NA

0 participants

Functional Brain Imaging and Psychological Testing in Women With Chronic Pelvic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2015-06-30

Completion:

2016-06-30

Conditions

• Pelvis Pain Chronic
• Endometriosis of Uterus

Interventions

• OTHER

No Results Yet

NCT02140255 | RECRUITING | PHASE1/PHASE2

1120 participants

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2015-01-23

Completion:

2028-01-31

Conditions

• HIV Infection

Interventions

• DRUG

No Results Yet

NCT02118649 | COMPLETED | NA

100 participants

Enhancing Behavior and Brain Response to Visual Targets Using a Computer Game

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2014-04-01

Completion:

2017-07-18

Conditions

• Neurodevelopmental Disorders

Interventions

• BEHAVIORAL

No Results Yet

NCT02102165 | RECRUITING | NA

1000 participants

AURORA: Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2014-04-30

Completion:

2027-12-31

Conditions

• Metastatic Breast Cancer

Interventions

• PROCEDURE

No Results Yet

NCT02028455 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

167 participants

A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD19 for Relapsed/Refractory CD19+ Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2014-02-11

Completion:

2021-08-10

Conditions

• CD19+ Acute Leukemia

Interventions

• BIOLOGICAL

Results Available

NCT02025153 | COMPLETED | NA

216 participants

Comprehensive Pain Programme to Determine Mechanism of Transition of Acute to Chronic Postsurgical Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2013-09-30

Completion:

2017-06-30

Conditions

• Chronic Pain
• Anaesthesia
• Genetics Predisposition

Interventions

• OTHER

No Results Yet

NCT01979523 | ACTIVE_NOT_RECRUITING | PHASE2

42 participants

Trametinib With or Without GSK2141795 in Treating Patients With Metastatic Uveal Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2013-11-21

Completion:

2017-09-01

Conditions

• Recurrent Uveal Melanoma
• Stage IV Uveal Melanoma AJCC v7

Interventions

• OTHER
• DRUG

Results Available

NCT01940094 | COMPLETED | PHASE3

159 participants

The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2014-02-28

Completion:

2024-12-31

Conditions

• Granulomatosis With Polyangiitis

Interventions

• DRUG

Results Available

NCT01893385 | TERMINATED | PHASE2

37 participants

Vitamin D Supplementation and the Immune Response

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2013-06-30

Completion:

2014-11-30

Conditions

• D Vitamin Deficiency Patients

Interventions

• DRUG

No Results Yet

NCT01891318 | RECRUITING | PHASE1/PHASE2

36 participants

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2013-07-03

Completion:

2026-09-30

Conditions

• Tumors Metastatic to Brain

Interventions

• RADIATION
• PROCEDURE

No Results Yet

NCT01873326 | ACTIVE_NOT_RECRUITING | PHASE2

92 participants

Paclitaxel, Ifosfamide and Cisplatin (TIP) Versus Bleomycin, Etoposide and Cisplatin (BEP) for Patients With Previously Untreated Intermediate- and Poor-risk Germ Cell Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2013-06-30

Completion:

2027-06-30

Conditions

• Germ Cell Tumors

Interventions

• DRUG

No Results Yet

NCT01837862 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

10 participants

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2013-10-22

Completion:

2027-03-31

Conditions

• Pilomyxoid Astrocytoma
• Pilocytic Astrocytoma
• Glioma, Astrocytic
• Optic Nerve Glioma
• Pleomorphic Xanthoastrocytoma
• Glioblastoma Multiforme
• Anaplastic Astrocytoma
• Gliosarcoma
• Diffuse Intrinsic Pontine Glioma
• DIPG
• Low-grade Glioma
• Brainstem Glioma

Interventions

• DRUG

No Results Yet

NCT01828788 | COMPLETED | PHASE2

120 participants

Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications. Effects of a Continuous Bi-laterosternal Infusion of Ropivacaine Through Multihole Catheters

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2013-04-27

Completion:

2015-01-19

Conditions

• Scheduled Cardiac Surgery
• Sternotomy
• Elderly Patients
• Obesity
• Chronic Bronchitis

Interventions

• DRUG

No Results Yet

NCT01730131 | RECRUITING

700 participants

Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2012-11-08

Completion:

2052-01-01

Conditions

• Progressive Multifocal Leukoencephalopathy

No Results Yet

NCT01568697 | RECRUITING

700 participants

Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2012-10-05

Conditions

• Immunosuppression
• Periodontal Disease
• Healthy Subjects
• Healthy Volunteer

No Results Yet

NCT01547741 | COMPLETED | PHASE3

4242 participants

Docetaxel and Cyclophosphamide Compared to Anthracycline-Based Chemotherapy in Treating Women With HER2-Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2012-04-30

Completion:

2022-05-31

Conditions

• Breast Cancer

Interventions

• DRUG

Results Available

NCT01334645 | COMPLETED | NA

134 participants

Copeptin and Acute Coronary Syndrome Without ST-segment Elevation

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2011-03-31

Completion:

2012-03-31

Conditions

• Chest Pain

Interventions

• OTHER

No Results Yet

NCT01152762 | COMPLETED | NA

129 participants

Effectiveness of Standardized Respiratory Physiotherapy in Primary Care (FREAP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2007-09-30

Completion:

2008-07-31

Conditions

• COPD

Interventions

• PROCEDURE

Results Available

NCT01050504 | RECRUITING

1500 participants

Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2009-08-31

Completion:

2029-01-31

Conditions

• Localized Renal Pelvis and Ureter Urothelial Carcinoma
• Malignant Solid Neoplasm
• Metastatic Malignant Neoplasm in the Bone
• Metastatic Malignant Neoplasm in the Soft Tissues
• Metastatic Renal Pelvis and Ureter Urothelial Carcinoma
• Recurrent Bladder Carcinoma
• Recurrent Prostate Carcinoma
• Recurrent Renal Pelvis and Ureter Urothelial Carcinoma
• Stage IV Bladder Cancer AJCC v7
• Stage IV Bladder Urothelial Carcinoma AJCC v7
• Stage IV Prostate Cancer AJCC v7

Interventions

• OTHER

No Results Yet

NCT00923026 | ENROLLING_BY_INVITATION

1150 participants

Follow Up Protocol for Subjects Previously Enrolled on NCI Surgery Branch Studies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-06

Start Date:

2009-06-15

Conditions

• Melanoma
• Adenocarcinoma
• Carcinoma NOS
• Neuroendocrine Tumors

No Results Yet

NCT00777582 | ACTIVE_NOT_RECRUITING | PHASE1

197 participants

Phase I Comparative Bioavailability Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-06

Start Date:

2008-10-27

Completion:

2009-02-06

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT07748598 | RECRUITING | NA

69 participants

HER2+ CNS Surveillance

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2025-10-03

Completion:

2026-12-31

Conditions

• Her 2 Positive Breast Cancer
• Cancer
• CNS

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT07748585 | COMPLETED | NA

60 participants

Effect of Titanium-Prepared Platelet-Rich Fibrin and Low-Level Laser Therapy on Postoperative Morbidity After Mandibular Third Molar Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2025-12-27

Completion:

2026-06-22

Conditions

• Impacted Mandibular Third Molar Extraction

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT07748572 | RECRUITING

200 participants

PMCF Registry to Describe the Safety and Performance of p64, p48 MW and p64 MW in France

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-05

Start Date:

2025-03-07

Completion:

2028-10-31

Conditions

• Intracranial Aneurysms

Interventions

• DEVICE

No Results Yet

NCT07748559 | COMPLETED | NA

52 participants

Impact of High-Oleic Palm Oil Consumption on Cardiovascular Biomarkers in Adults in Bogotá

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2024-10-22

Completion:

2025-09-27

Conditions

• Insulinemic Response
• Type 2 Diabetes (Adult Onset)
• Hyperglycaemia (Diabetic)
• Hyperlipidaemia

Interventions

• OTHER

No Results Yet

NCT07748546 | NOT_YET_RECRUITING | NA

159 participants

The Rebound Effect on Repeated Low-Level Red Light Therapy for Myopia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-05

Start Date:

2026-08-15

Completion:

2027-12-31

Conditions

• Myopia
• Randomized Controlled Trial (RCT)

Interventions

• DEVICE

No Results Yet