Comprehensive Pain Programme to Determine Mechanism of Transition of Acute to Chronic Postsurgical Pain
NCT02025153 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 216
Last updated 2020-08-05
Summary
To determine whether central sensitization is a mechanism of CPSP (chronic postsurgical pain) in women who will develop CPSP compared to women with no CPSP after hysterectomy. This mechanism is illustrated by a higher pain score in experimental pain models such as tonic heat stimulation, increased evoked mechanical temporal summation and increased wound hyperalgesia.
Conditions
- Chronic Pain
- Anaesthesia
- Genetics Predisposition
Interventions
- OTHER
-
pain testing
physical testing, psychological testing, genetics testing and functional brain imaging
Sponsors & Collaborators
-
KK Women's and Children's Hospital
lead OTHER_GOV
Principal Investigators
-
Ban Leong Sng, Dr · KK Women's and Children's Hospital
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 21 Years
- Max Age
- 70 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-09-30
- Primary Completion
- 2017-06-30
- Completion
- 2017-06-30
Countries
- Singapore
Study Locations
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