Clinical Trials

NCT05091424 | RECRUITING | PHASE1

332 participants

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2022-03-07
Completion:: 2031-02-10

Conditions

Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Interventions

DRUG

No Results Yet

NCT05087745 | RECRUITING | EARLY_PHASE1

50 participants

A Clinical Study on TIL for the Treatment of Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-12-10
Completion:: 2027-12-10

Conditions

Advanced Solid Tumor
Tumor Infiltrating Lymphocytes
Treatment Side Effects
Effects of Immunotherapy

Interventions

BIOLOGICAL

No Results Yet

NCT05086900 | COMPLETED

283 participants

Developing a PROM for Recurrent Urinary Tract Infection

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-05-01
Completion:: 2021-09-01

Conditions

Urologic Diseases
Patient Satisfaction
Pain, Chronic
Sexual Dysfunction

Interventions

OTHER

Results Available

NCT05039619 | RECRUITING | PHASE2

40 participants

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2022-05-12
Completion:: 2028-06-15

Conditions

Lupus Nephritis

Interventions

DRUG

No Results Yet

NCT05008848 | RECRUITING | PHASE3

600 participants

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2022-04-01
Completion:: 2027-03-01

Conditions

Cigarette Smoking-Related Carcinoma

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT04999761 | RECRUITING | PHASE1

917 participants

AB122 Platform Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-06-01
Completion:: 2027-06-30

Conditions

Advanced or Metastatic Solid Tumor
Pancreatic Ductal Adenocarcinoma
Colorectal Cancer
Non-small Cell Lung Cancer
Gastric Cancer
Alveolar Soft Part Sarcoma
Esophageal Cancer
Head and Neck Cancer
Biliary Tract Cancer

Interventions

DRUG

No Results Yet

NCT04967833 | RECRUITING | EARLY_PHASE1

20 participants

A Study of GC101 TIL in Advanced Solid Tumors (TR)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-04-22
Completion:: 2027-12-22

Conditions

Advanced Solid Tumors

Interventions

BIOLOGICAL

No Results Yet

NCT04960072 | RECRUITING | EARLY_PHASE1

50 participants

A Study of GC101 TIL in r/r Gastrointestinal Tumors (10hospital)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-06-30
Completion:: 2027-12-30

Conditions

Gastrointestinal Tumor

Interventions

BIOLOGICAL

No Results Yet

NCT04943913 | RECRUITING | EARLY_PHASE1

50 participants

Study of GC101 TIL in Brain Glioma (Soochow2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-05-06
Completion:: 2026-12-30

Conditions

Glioma

Interventions

BIOLOGICAL

No Results Yet

NCT04929236 | RECRUITING | PHASE3

30 participants

Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2023-10-01
Completion:: 2028-12-31

Conditions

Pediatric Chronic Inflammatory Demyelinating Polyneuropathy

Interventions

DRUG

No Results Yet

NCT04923555 | COMPLETED | NA

33 participants

Analysis of the Postprandial Effects of a Vegetable Protein Mixture Rich in Arginine, Cysteine and Leucine on Endothelial Dysfunction and Inflammation at Low Noise in Elderly People With Cardiometabolic Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-11-09
Completion:: 2022-06-07

Conditions

Metabolic Syndrome
Predisposition to Cardiovascular Disease

Interventions

BEHAVIORAL

No Results Yet

NCT04919122 | ACTIVE_NOT_RECRUITING

468 participants

Outcomes Database to prospectivelY aSSEss the Changing TherapY Landscape in Renal Cell Carcinoma

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-05
Start Date:: 2022-04-01
Completion:: 2026-12-31

Conditions

Metastatic Renal Cell Carcinoma

No Results Yet

NCT04906096 | RECRUITING | PHASE2

25 participants

Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-06-01
Completion:: 2026-12-01

Conditions

Primary Central Nervous System Lymphoma
Non-Hodgkin Lymphoma of Extranodal Site

Interventions

DRUG

No Results Yet

NCT04900623 | RECRUITING | PHASE2

145 participants

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-07-02
Completion:: 2030-06-01

Conditions

HPV-Associated Oropharyngeal Squamous Cell Carcinoma
HPV Positive Oropharyngeal Squamous Cell Carcinoma
HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Stage
HPV-Related Squamous Cell Carcinoma
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Clinical Stage
HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Pathologic Stage

Interventions

DEVICE
RADIATION
DRUG

No Results Yet

NCT04892823 | RECRUITING

110 participants

Social Relationships and Accelerated Aging in Hematopoietic Cell Transplant Survivors

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-05-18
Completion:: 2027-07-16

Conditions

Hematopoietic and Lymphoid Cell Neoplasm

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04891640 | COMPLETED | PHASE4

164 participants

Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-11-11
Completion:: 2026-06-01

Conditions

Juvenile Spondyloarthritis

Interventions

OTHER

No Results Yet

NCT04889911 | COMPLETED | NA

17 participants

Pilot RCT of Self-stigma Treatment for First Episode Psychosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2023-08-01
Completion:: 2025-10-27

Conditions

First Episode Psychosis
Youth

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT04855305 | COMPLETED | PHASE2

47 participants

Optimizing and Standardizing 129Xe Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-11-12
Completion:: 2025-06-11

Conditions

Interstitial Lung Diseases

Interventions

DRUG

Results Available

NCT04851288 | COMPLETED | PHASE2

112 participants

Mitochondrial-targeted Antioxidant Supplementation for Improving Age-related Vascular Dysfunction in Humans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-04-02
Completion:: 2025-12-01

Conditions

Aging

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04840563 | COMPLETED | NA

10 participants

Surface Refractive Index Shift of Kalifilcon A Compared With Dailies Total1 and Precision1 Lenses

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-04-07
Completion:: 2021-04-15

Conditions

Contact Lens Wear

Interventions

DEVICE

Results Available

NCT04833790 | COMPLETED | NA

2451 participants

What Drives Poor Care for Child Diarrhea: A Standardized Patient Experiment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2022-05-05
Completion:: 2022-12-31

Conditions

Child Diarrhea

Interventions

BEHAVIORAL

Results Available

NCT04827862 | COMPLETED | PHASE2

6 participants

RADVAX™ for Relapsed/Refractory Non-Hodgkin Lymphoma: A Phase II Trial of Pembrolizumab + Low Dose Radiotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2022-07-01
Completion:: 2026-05-01

Conditions

Non Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT04810871 | SUSPENDED | NA

40 participants

Surgical Resection of Latent Brain Tumors Prior to Recurrence

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-05-06
Completion:: 2028-03-01

Conditions

Brain Neoplasm

Interventions

PROCEDURE

No Results Yet

NCT04802759 | RECRUITING | PHASE1/PHASE2

316 participants

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-06-22
Completion:: 2029-05-30

Conditions

Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer

Interventions

DRUG

No Results Yet

NCT04794075 | RECRUITING | NA

300 participants

Therapeutic Education and Nursing Support Program for Supportive Care, in Patients Treated With Hormone Therapy for Non-metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-08-09
Completion:: 2028-08-31

Conditions

Neoplasm of Breast

Interventions

OTHER

No Results Yet

NCT04788836 | COMPLETED

61 participants

How Altered Gut-Brain-Axis Influences Food Choices: Part 2 (BrainFood)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-11-01
Completion:: 2025-12-31

Conditions

Food Preferences
Obesity

Interventions

OTHER

No Results Yet

NCT04743401 | COMPLETED | NA

54 participants

Feasibility of a Tele-game-based Exercise (Tele-exergame) Program to Prevent Deconditioning in Hospitalized COVID-19 Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-07-05
Completion:: 2023-12-31

Conditions

COVID 19
Rehabilitation
Inpatient
Hospitalized

Interventions

OTHER

Results Available

NCT04739189 | COMPLETED | NA

20 participants

Appetite Response to Exercise- Versus Energy Restriction-induced Energy Deficit in Adolescents With Obesity.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-08-28
Completion:: 2021-10-03

Conditions

Pediatric Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT04730479 | COMPLETED

330 participants

Echography to Predict Radial Artery Catheterization Failure (EPRAC)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-04-15
Completion:: 2022-04-06

Conditions

Cardiac and Aortic Surgery

No Results Yet

NCT04729933 | ACTIVE_NOT_RECRUITING | NA

16 participants

Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-03-11
Completion:: 2025-01-03

Conditions

Heart Failure
Mitral Regurgitation

Interventions

DEVICE

Results Available

NCT04713982 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

30 participants

Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-11-19
Completion:: 2027-06-30

Conditions

Huntington Disease

Interventions

DRUG

No Results Yet

NCT04651504 | COMPLETED | NA

185903 participants

Rural Colon Cancer Screening Toolkit Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2020-12-02
Completion:: 2024-12-31

Conditions

Colon Cancer Screening

Interventions

OTHER

Results Available

NCT04649086 | TERMINATED | NA

60 participants

Muscular Rehabilitation by Eccentric Exercise After Severe COVID-19 Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2020-06-05
Completion:: 2022-01-07

Conditions

Covid19
Sarcopenia
Muscle Weakness

Interventions

OTHER

No Results Yet

NCT04624581 | COMPLETED | NA

260 participants

FIbromyalgia anD GenetIcs Subgroups (FIDGIS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2020-11-30
Completion:: 2022-01-17

Conditions

Fibromyalgia

Interventions

DEVICE

No Results Yet

NCT04613596 | RECRUITING | PHASE2/PHASE3

626 participants

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2020-12-02
Completion:: 2028-10-31

Conditions

Advanced Non-Small Cell Lung Cancer
Metastatic Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT04589845 | ACTIVE_NOT_RECRUITING | PHASE2

920 participants

Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-01-18
Completion:: 2032-09-25

Conditions

Solid Tumors

Interventions

DRUG

No Results Yet

NCT04577755 | ACTIVE_NOT_RECRUITING | PHASE2

45 participants

Pomalidomide Treatment in Patients With Kaposi Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2022-03-18
Completion:: 2026-10-01

Conditions

Skin Kaposi Sarcoma

Interventions

PROCEDURE
DRUG

No Results Yet

NCT04539366 | SUSPENDED | PHASE1

73 participants

Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, GD2-CAR PERSIST Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2022-01-25
Completion:: 2040-12-31

Conditions

Recurrent Childhood Neuroblastoma
Recurrent Childhood Osteosarcoma
Recurrent Neuroblastoma
Recurrent Osteosarcoma
Refractory Childhood Neuroblastoma
Refractory Childhood Osteosarcoma
Refractory Neuroblastoma
Refractory Osteosarcoma

Interventions

DRUG
PROCEDURE
BIOLOGICAL
OTHER

No Results Yet

NCT04502758 | COMPLETED | NA

58 participants

Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2022-04-04
Completion:: 2026-06-30

Conditions

Suicidal Ideation
Major Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT04502407 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Trial of De-Intensified Post-operative Chemoradiation Following Robotic Surgery for HPV-positive Oropharyngeal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-05
Start Date:: 2021-02-16
Completion:: 2026-12-15

Conditions

HPV Positive Oropharyngeal Squamous Cell Carcinoma

Interventions

RADIATION
DRUG

No Results Yet