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Clinical Trials

Showing trials with last updates posted in 2026.

NCT05579366 | RECRUITING | PHASE1/PHASE2
884 participants

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-04
Start Date:
2022-12-07
Completion:
2027-07-31
Conditions
  • High Grade Epithelial Ovarian Cancer
  • High Grade Serous Ovarian Cancer
  • Primary Peritoneal Carcinoma
  • Fallopian Tube Cancer
  • Endometrial Cancer
  • Non-small Cell Lung Cancer
  • Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (NSCLC)
  • Mesothelioma
  • Breast Adenocarcinoma
  • Triple Negative Breast Cancer
  • Hormone Receptor-positive/Her2 Negative Breast Cancer
  • Platinum-resistant Ovarian Cancer (PROC)
  • Platinum Sensitive Ovarian Cancer (PSOC)
  • Primary Refractory Ovarian Cancer
  • Uterine Cancer
Interventions
  • DRUG
No Results Yet
NCT05564403 | ACTIVE_NOT_RECRUITING | PHASE2
66 participants

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-04
Start Date:
2024-02-09
Completion:
2026-10-01
Conditions
  • Advanced Biliary Tract Carcinoma
  • Advanced Gallbladder Carcinoma
  • Advanced Intrahepatic Cholangiocarcinoma
  • Recurrent Biliary Tract Carcinoma
  • Recurrent Gallbladder Carcinoma
  • Recurrent Intrahepatic Cholangiocarcinoma
  • Stage III Distal Bile Duct Cancer AJCC v8
  • Stage III Gallbladder Cancer AJCC v8
  • Stage III Hilar Cholangiocarcinoma AJCC v8
  • Stage III Intrahepatic Cholangiocarcinoma AJCC v8
  • Stage IV Distal Bile Duct Cancer AJCC v8
  • Stage IV Gallbladder Cancer AJCC v8
  • Stage IV Hilar Cholangiocarcinoma AJCC v8
  • Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
  • Unresectable Biliary Tract Carcinoma
  • Unresectable Gallbladder Carcinoma
  • Unresectable Intrahepatic Cholangiocarcinoma
Interventions
  • DRUG
  • PROCEDURE
No Results Yet
NCT05554328 | ACTIVE_NOT_RECRUITING | PHASE2
165 participants

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-04
Start Date:
2023-04-25
Completion:
2028-10-01
Conditions
  • Recurrent Endometrial Carcinoma
  • Recurrent Fallopian Tube Carcinoma
  • Recurrent Ovarian Carcinoma
  • Recurrent Primary Peritoneal Carcinoma
Interventions
  • PROCEDURE
  • DRUG
No Results Yet
NCT05199285 | TERMINATED | PHASE2
15 participants

A Phase II Study of Nivolumab + Ipilimumab in Advanced HCC Patients Who Have Progressed on First Line Atezolizumab + Bevacizumab

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-04
Start Date:
2023-01-19
Completion:
2026-02-01
Conditions
  • BCLC Stage B Hepatocellular Carcinoma
  • BCLC Stage C Hepatocellular Carcinoma
  • Locally Advanced Hepatocellular Carcinoma
  • Metastatic Hepatocellular Carcinoma
  • Stage III Hepatocellular Carcinoma AJCC v8
  • Stage IIIA Hepatocellular Carcinoma AJCC v8
  • Stage IIIB Hepatocellular Carcinoma AJCC v8
  • Stage IV Hepatocellular Carcinoma AJCC v8
  • Stage IVA Hepatocellular Carcinoma AJCC v8
  • Stage IVB Hepatocellular Carcinoma AJCC v8
  • Unresectable Hepatocellular Carcinoma
Interventions
  • BIOLOGICAL
No Results Yet
NCT05168163 | RECRUITING | PHASE2
122 participants

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-04
Start Date:
2022-05-27
Completion:
2026-06-30
Conditions
  • Locally Advanced Hepatocellular Carcinoma
  • Metastatic Hepatocellular Carcinoma
  • Stage III Hepatocellular Carcinoma AJCC v8
  • Stage IIIA Hepatocellular Carcinoma AJCC v8
  • Stage IIIB Hepatocellular Carcinoma AJCC v8
  • Stage IV Hepatocellular Carcinoma AJCC v8
  • Stage IVA Hepatocellular Carcinoma AJCC v8
  • Stage IVB Hepatocellular Carcinoma AJCC v8
  • Unresectable Hepatocellular Carcinoma
Interventions
  • BIOLOGICAL
  • DRUG
No Results Yet
NCT05111574 | ACTIVE_NOT_RECRUITING | PHASE2
101 participants

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-04
Start Date:
2022-08-11
Completion:
2027-07-15
Conditions
  • Anal Melanoma
  • Bladder Melanoma
  • Cervical Melanoma
  • Esophageal Melanoma
  • Gallbladder Melanoma
  • Head and Neck Mucosal Melanoma
  • Mucosal Melanoma
  • Nasopharyngeal Mucosal Melanoma
  • Oral Cavity Mucosal Melanoma
  • Penile Mucosal Melanoma
  • Rectal Melanoma
  • Recurrent Mucosal Melanoma
  • Sinonasal Mucosal Melanoma
  • Urethral Melanoma
  • Urinary System Mucosal Melanoma
  • Vaginal Melanoma
  • Vulvar Melanoma
Interventions
  • PROCEDURE
  • BIOLOGICAL
  • DRUG
No Results Yet
NCT05080166 | COMPLETED | NA
74 participants

UPLYFT For Lymphoma Survivors

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-04
Start Date:
2022-02-08
Completion:
2026-07-17
Conditions
  • Lymphoma
  • Survivorship
Interventions
  • OTHER
  • BEHAVIORAL
No Results Yet
NCT04949100 | ACTIVE_NOT_RECRUITING | NA
50 participants

Microcurrent for Fibromyalgia

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-04
Start Date:
2021-10-25
Completion:
2026-12-31
Conditions
  • Fibromyalgia
Interventions
  • DEVICE
No Results Yet
NCT04943861 | RECRUITING | NA
200 participants

Human Immunodeficiency Virus (HIV) Food Insecurities

Study Type:
INTERVENTIONAL
Last Updated:
2026-08-04
Start Date:
2023-12-01
Completion:
2027-02-28
Conditions
  • Food Insecurities
  • Cardiometabolic Comorbidities
  • HIV
  • PreDiabetes
  • Type 2 Diabetes Mellitus (T2DM)
Interventions
  • BEHAVIORAL
  • OTHER
No Results Yet
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