Clinical Trials

NCT02213926 | ACTIVE_NOT_RECRUITING | PHASE2

124 participants

An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2015-03-02

Completion:

2020-12-04

Conditions

• Mantle Cell Lymphoma (MCL)

Interventions

• DRUG

Results Available

NCT02211768 | COMPLETED | PHASE1

10 participants

Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-12-08

Completion:

2017-09-05

Conditions

• Neurofibromatosis
• MPNST

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT02196181 | ACTIVE_NOT_RECRUITING | PHASE2

280 participants

Testing Two Different Treatment Schedules of Dabrafenib and Trametinib for Skin Cancer Which Has Spread

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-09-19

Completion:

2027-03-15

Conditions

• Stage III Cutaneous Melanoma AJCC v7
• Stage IV Cutaneous Melanoma AJCC v6 and v7
• Unresectable Melanoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT02143414 | ACTIVE_NOT_RECRUITING | PHASE2

53 participants

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2015-06-30

Completion:

2022-06-01

Conditions

• Acute Lymphoblastic Leukemia
• B Acute Lymphoblastic Leukemia
• B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
• Recurrent Acute Lymphoblastic Leukemia
• Refractory Acute Lymphoblastic Leukemia

Interventions

• PROCEDURE
• BIOLOGICAL
• DRUG

Results Available

NCT02115282 | ACTIVE_NOT_RECRUITING | PHASE3

608 participants

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-03-29

Completion:

2020-05-05

Conditions

• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Breast Adenocarcinoma
• HER2/Neu Negative
• Locally Advanced Breast Carcinoma
• Metastatic Breast Carcinoma
• Recurrent Breast Carcinoma

Interventions

• PROCEDURE
• DRUG
• OTHER

Results Available

NCT02101788 | COMPLETED | PHASE2/PHASE3

260 participants

Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-04-11

Completion:

2019-04-04

Conditions

• Borderline Ovarian Serous Tumor
• Micropapillary Serous Carcinoma
• Ovarian Serous Adenocarcinoma
• Primary Peritoneal Serous Adenocarcinoma
• Recurrent Ovarian Low Grade Serous Adenocarcinoma
• Recurrent Primary Peritoneal Serous Adenocarcinoma

Interventions

• DRUG
• OTHER

Results Available

NCT02075463 | TERMINATED | PHASE2

15 participants

Study to Evaluate the Safety and Efficacy of GSK1278863 in Recombinant Human Erythropoietin (rhEPO) Hyporesponsive Hemodialysis-dependent Chronic Kidney Disease Subjects With Anemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-06-11

Completion:

2016-03-16

Conditions

• Anemia
• Anaemia

Interventions

• DRUG

Results Available

NCT02048813 | ACTIVE_NOT_RECRUITING | PHASE3

529 participants

Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-03-10

Completion:

2018-10-24

Conditions

• Anemia
• Chronic Lymphocytic Leukemia
• Small Lymphocytic Lymphoma

Interventions

• DRUG
• OTHER
• BIOLOGICAL

Results Available

NCT02003222 | ACTIVE_NOT_RECRUITING | PHASE3

488 participants

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2014-05-19

Completion:

2023-06-23

Conditions

• Acute Lymphoblastic Leukemia
• B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

Results Available

NCT01933620 | ENROLLING_BY_INVITATION

250 participants

Studies of the Human Microbiome in Clinical Center Patients

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2014-01-28

Completion:

2028-10-16

Conditions

• Multidrug-resistant Colonization

No Results Yet

NCT01900132 | RECRUITING | NA

275 participants

Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2013-06-20

Completion:

2027-06-01

Conditions

• Neuromuscular Disease
• Motor Neuron Disease
• Inherited Neuromuscular Conditions
• Inherited Neuropathies

Interventions

• DEVICE

No Results Yet

NCT01845883 | WITHDRAWN | NA

0 participants

Perceptual Decision Making Under Conditions of Visual Uncertainty

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2013-04-30

Completion:

2015-12-31

Conditions

• Parkinson's Disease
• Dystonia
• Ataxia

Interventions

• PROCEDURE

No Results Yet

NCT01639508 | RECRUITING | PHASE2

86 participants

Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2012-07-31

Completion:

2027-07-31

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT01524549 | COMPLETED

178 participants

Blood Vessel Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2012-03-01

Conditions

• Cardiovascular Disease

No Results Yet

NCT01445288 | COMPLETED

76 participants

Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2006-12-05

Conditions

• Diffuse Intrinsic Pontine Glioma
• PNET
• Ependymoma
• Germinoma
• Medulloblastoma

No Results Yet

NCT01439659 | ACTIVE_NOT_RECRUITING | PHASE2

75 participants

Juice Plus+ and Juice Plus+ Complete in Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2003-02-18

Completion:

2028-03-01

Conditions

• Ovarian Cancer

Interventions

• BEHAVIORAL
• DIETARY_SUPPLEMENT

No Results Yet

NCT01399385 | RECRUITING | NA

4000 participants

New Heart Imaging Techniques to Evaluate Possible Heart Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2011-07-06

Completion:

2028-11-06

Conditions

• Healthy
• Obesity
• Diabetes
• Healthy Volunteers
• Atherosclerosis

Interventions

• DEVICE

No Results Yet

NCT01386385 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

53 participants

Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2011-06-20

Completion:

2019-05-26

Conditions

• Lung Adenocarcinoma
• Lung Adenocarcinoma, Mixed Subtype
• Lung Large Cell Carcinoma
• Lung Squamous Cell Carcinoma
• Minimally Invasive Lung Adenocarcinoma
• Stage III Lung Non-Small Cell Cancer AJCC v7
• Stage IIIA Lung Non-Small Cell Cancer AJCC v7
• Stage IIIB Lung Non-Small Cell Cancer AJCC v7

Interventions

• RADIATION
• DRUG
• OTHER

Results Available

NCT01352975 | COMPLETED

217 participants

Study of Dark Adaptation in Age-Related Macular Degeneration

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2011-05-16

Conditions

• Age-Related Macular Degeneration

No Results Yet

NCT01274338 | ACTIVE_NOT_RECRUITING | PHASE3

1673 participants

Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2011-06-17

Completion:

2019-02-15

Conditions

• Melanoma of Unknown Primary
• Recurrent Melanoma
• Stage IIIB Cutaneous Melanoma AJCC v7
• Stage IIIC Cutaneous Melanoma AJCC v7
• Stage IV Cutaneous Melanoma AJCC v6 and v7

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT01272037 | ACTIVE_NOT_RECRUITING | PHASE3

5018 participants

Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2011-02-28

Completion:

2023-02-01

Conditions

• Breast Ductal Carcinoma In Situ
• Invasive Breast Carcinoma
• Multicentric Breast Carcinoma
• Multifocal Breast Carcinoma
• Synchronous Bilateral Breast Carcinoma

Interventions

• DRUG
• OTHER

Results Available

NCT01169337 | ACTIVE_NOT_RECRUITING | PHASE3

226 participants

Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2011-01-24

Completion:

2019-01-25

Conditions

• Light Chain Deposition Disease
• Smoldering Multiple Myeloma

Interventions

• OTHER
• DRUG

Results Available

NCT01164241 | COMPLETED

945 participants

Natural History of Severe Allergic Inflammation and Reactions

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2010-07-12

Conditions

• PGM3 Deficiency
• Eosinophilic and/or Atopic Dermatitis
• OSMR Deficiency
• Primary Localized Cutaneous Amyloidosis
• Hereditary Alpha-tryptasemia

No Results Yet

NCT01143558 | COMPLETED | EARLY_PHASE1

45 participants

Searching for Persistence of Infection in Lyme Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2010-11-04

Completion:

2014-12-30

Conditions

• Lyme Disease

Interventions

• DEVICE

No Results Yet

NCT01132885 | RECRUITING

415 participants

Defining the Brain Phenotype of Children With Williams Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2011-01-23

Conditions

• Williams Syndrome
• Duplication

No Results Yet

NCT01109394 | RECRUITING

6035 participants

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2010-04-21

Conditions

• Sarcoma
• Endocrine Tumors
• Neuroblastoma
• Retinoblastoma
• Renal Cancer

No Results Yet

NCT01064648 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

117 participants

Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2010-03-15

Completion:

2018-06-01

Conditions

• Epithelioid Mesothelioma
• Pleural Malignant Mesothelioma
• Recurrent Malignant Mesothelioma
• Sarcomatoid Mesothelioma

Interventions

• DRUG
• OTHER

Results Available

NCT01036581 | RECRUITING | NA

1000 participants

Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2003-10-24

Completion:

2029-12-31

Conditions

• Drug Abuse
• Nicotine Dependence

Interventions

• DEVICE

No Results Yet

NCT00977977 | RECRUITING | PHASE2

30 participants

Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2010-12-22

Completion:

2027-12-31

Conditions

• Nephrotic Syndrome
• Proteinuria
• Autoimmune Disease
• Glomerular Disease
• Membranous Glomerulonephritis

Interventions

• DRUG

No Results Yet

NCT00702533 | COMPLETED

80 participants

A New Method for Determining Gastric Acid Output Using a Wireless Capsule

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2008-06-18

Conditions

• Gastric Acid Secretory Disorders

Interventions

• DEVICE
• DRUG

No Results Yet

NCT00600665 | COMPLETED | NA

279 participants

Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2007-02-28

Completion:

2013-06-30

Conditions

• Anemia, Sickle Cell
• Hemoglobin SC Disease

Interventions

• BEHAVIORAL

Results Available

NCT00588770 | ACTIVE_NOT_RECRUITING | PHASE3

403 participants

Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2008-08-08

Completion:

2018-06-05

Conditions

• Neck Squamous Cell Carcinoma of Unknown Primary
• Recurrent Hypopharyngeal Squamous Cell Carcinoma
• Recurrent Laryngeal Squamous Cell Carcinoma
• Recurrent Laryngeal Verrucous Carcinoma
• Recurrent Lip and Oral Cavity Squamous Cell Carcinoma
• Recurrent Neck Squamous Cell Carcinoma of Unknown Primary
• Recurrent Oral Cavity Verrucous Carcinoma
• Recurrent Oropharyngeal Squamous Cell Carcinoma
• Recurrent Salivary Gland Carcinoma
• Recurrent Sinonasal Squamous Cell Carcinoma
• Salivary Gland Squamous Cell Carcinoma
• Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7
• Stage IV Major Salivary Gland Cancer AJCC v7
• Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7
• Stage IVA Laryngeal Verrucous Carcinoma AJCC v7
• Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
• Stage IVA Major Salivary Gland Cancer AJCC v7
• Stage IVA Oral Cavity Cancer AJCC v6 and v7
• Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7
• Stage IVA Sinonasal Squamous Cell Carcinoma AJCC v7
• Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7
• Stage IVB Laryngeal Verrucous Carcinoma AJCC v7
• Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
• Stage IVB Major Salivary Gland Cancer AJCC v7
• Stage IVB Oral Cavity Cancer AJCC v6 and v7
• Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7
• Stage IVB Sinonasal Squamous Cell Carcinoma AJCC v7
• Stage IVC Laryngeal Squamous Cell Carcinoma AJCC v7
• Stage IVC Laryngeal Verrucous Carcinoma AJCC v7
• Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
• Stage IVC Major Salivary Gland Cancer AJCC v7
• Stage IVC Oral Cavity Cancer AJCC v6 and v7
• Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7
• Stage IVC Sinonasal Squamous Cell Carcinoma AJCC v7
• Tongue Carcinoma

Interventions

• BIOLOGICAL
• DRUG
• OTHER

Results Available

NCT00365859 | COMPLETED | PHASE3

330 participants

Study of Aripiprazole in the Treatment of Serious Behavioral Problems in Children and Adolescents With Autistic Disorder (AD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2006-09-01

Completion:

2009-06-01

Conditions

• Autistic Disorder
• Behavioral Symptoms

Interventions

• DRUG

Results Available

NCT00098072 | COMPLETED | PHASE1

27 participants

Endothelial Cell Dysfunction in Pulmonary Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2000-05-17

Completion:

2009-07-08

Conditions

• Secondary Pulmonary Arterial Hypertension

Interventions

• PROCEDURE

No Results Yet

NCT00092222 | ACTIVE_NOT_RECRUITING | PHASE2

75 participants

Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-04

Start Date:

2004-10-28

Completion:

2026-10-01

Conditions

• Lymphoproliferative Disorder
• HHV-8
• Malignancy
• HIV

Interventions

• DRUG
• OTHER

No Results Yet

NCT00091871 | RECRUITING

50 participants

A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2005-06-08

Conditions

• Eosinophilia
• Hypereosinophilic Syndrome

No Results Yet

NCT00050752 | RECRUITING

1130 participants

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2003-02-24

Conditions

• Renal Tumor Histology
• Cutaneous Leiomyoma
• Kidney Cancer

No Results Yet

NCT00024479 | RECRUITING

7500 participants

Studies of the Natural History of Rheumatic Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2001-10-03

Conditions

• Rheumatic Diseases
• Arthritis

No Results Yet

NCT00023036 | COMPLETED

324 participants

Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-04

Start Date:

2001-09-04

Conditions

• Sensorineural Hearing Loss
• Cytomegalovirus Infection

No Results Yet

NCT07743424 | NOT_YET_RECRUITING | NA

30 participants

Effect of Trans-spinal Electromagnetic Neuromodulation in Treatment of Patients With Discogenic Lumbosacral Radiculopathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2026-08-01

Completion:

2026-08-01

Conditions

• Lumbar Radiculopathy
• Discogenic Lumbosacral Radiculopathy

Interventions

• OTHER

No Results Yet