Clinical Trials

NCT06326996 | RECRUITING | EARLY_PHASE1

52 participants

Thiamine Intervention and Coronary Artery Bypass Grafting

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-10-10
Completion:: 2026-09-30

Conditions

Coronary Heart Disease
Coronary Artery Bypass Grafting

Interventions

DRUG

No Results Yet

NCT06315556 | RECRUITING

200 participants

An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK)

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-03-05
Completion:: 2027-03-31

Conditions

Retinopathy of Prematurity
Preterm Infants

Interventions

DRUG

No Results Yet

NCT06312683 | RECRUITING | PHASE4

16 participants

Rifaximin for the Secondary Prevention of Recurrent Pouchitis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-07-01
Completion:: 2027-07-31

Conditions

Pouchitis

Interventions

DRUG

No Results Yet

NCT06305780 | COMPLETED | PHASE2

381 participants

RECOVER-AUTONOMIC Platform Protocol

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-03-11
Completion:: 2025-07-09

Conditions

Long COVID
Long Covid19
Long Covid-19

Interventions

DRUG

Results Available

NCT06305754 | ACTIVE_NOT_RECRUITING | PHASE3

551 participants

Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-06-11
Completion:: 2028-08-17

Conditions

Non-small Cell Lung Cancer (NSCLC)

Interventions

DRUG
BIOLOGICAL

No Results Yet

NCT06291207 | COMPLETED | PHASE3

254 participants

A Study to Evaluate the Efficacy and Safety of AD-224

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-04-15
Completion:: 2025-04-07

Conditions

Hypertension,Essential

Interventions

DRUG

No Results Yet

NCT06281886 | COMPLETED | PHASE2

170 participants

Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-02-15
Completion:: 2026-06-25

Conditions

Esophageal Squamous Cell Carcinoma
Efficacy
Toxicity

Interventions

DRUG
RADIATION

No Results Yet

NCT06270706 | RECRUITING | PHASE1

124 participants

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-08-30
Completion:: 2030-06-30

Conditions

Advanced or Metastatic Solid Tumor

Interventions

DRUG

No Results Yet

NCT06258902 | RECRUITING

20 participants

Odevixibat Pregnancy and Lactation Surveillance Program: A Study to Evaluate the Safety of Odevixibat During Pregnancy and/or Lactation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-09-28
Completion:: 2032-05-31

Conditions

Pregnancy Related

No Results Yet

NCT06246643 | ACTIVE_NOT_RECRUITING | PHASE2

13 participants

A Study of Continued Treatment With Regorafenib in Participants With Solid Tumors Who Have Participated in Other Bayer Studies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-01-24
Completion:: 2028-04-27

Conditions

Solid Malignant Tumors

Interventions

DRUG

No Results Yet

NCT06239272 | RECRUITING | PHASE1/PHASE2

139 participants

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-03-27
Completion:: 2034-06-30

Conditions

Adipocytic Neoplasm
Liposarcoma
Atypical Fibroxanthoma
Angiomatoid Fibrous Histiocytoma
Fibrosarcoma NOS
Myxofibrosarcoma
Angiosarcoma
Osteosarcoma, Extraskeletal
Dedifferentiated Liposarcoma
Myxoid Liposarcoma
Pleomorphic Liposarcoma
Myxoid Pleomorphic Liposarcoma
Low Grade Fibromyxoid Sarcoma
Sclerosing Epithelioid Fibrosarcoma
Malignant Tenosynovial Giant Cell Tumor of Soft Tissue
Epithelioid Hemangioendothelioma
Glomus Tumor
Inflammatory Leiomyosarcoma
Leiomyosarcoma
Ossifying Fibromyxoid Tumor, Malignant
Myoepithelioma
Synovial Sarcoma
Epithelioid Sarcoma
Perineurioma, Malignant
Clear Cell Sarcoma
Extraskeletal Myxoid Chondrosarcoma
Granular Cell Tumor, Malignant
Melanotic Malignant Nerve Sheath Tumor
Malignant Peripheral Nerve Sheath Tumor
Perivascular Epithelioid Tumor, Malignant
Intimal Sarcoma
Myoepithelial Carcinoma
Undifferentiated Sarcoma
Pleomorphic Sarcoma, Undifferentiated
Round Cell Sarcoma, Undifferentiated
NTRK-Rearranged Spindle Cell Neoplasm
Phosphaturic Mesenchymal Tumor, Malignant
Round Cell Sarcoma
Well Differentiated Liposarcoma
Giant Cell Tumor of Soft Parts NOS
Low Grade Myofibroblastic Sarcoma
Dermatofibrosarcoma Protuberans, Fibrosarcomatous

Interventions

PROCEDURE
RADIATION
DRUG

No Results Yet

NCT06224205 | COMPLETED | NA

1281 participants

Digital Detection of Dementia (D Cubed) Studies: D3

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-11-08
Completion:: 2025-11-08

Conditions

Alzheimer Disease and Related Dementias (ADRD)

Interventions

OTHER

No Results Yet

NCT06221423 | WITHDRAWN

0 participants

Fruquintinib Combined With TAS-102 in Refractory Metastatic Colorectal Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-01-01
Completion:: 2024-05-31

Conditions

Colorectal Cancer
Metastatic Colorectal Cancer
Refractory Colorectal Carcinoma

Interventions

DRUG

No Results Yet

NCT06220201 | ACTIVE_NOT_RECRUITING | PHASE1

120 participants

A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-03-28
Completion:: 2027-07-15

Conditions

Multiple Sclerosis
Myasthenia Gravis

Interventions

DRUG

No Results Yet

NCT06217562 | COMPLETED | PHASE4

3959 participants

Vasopressin for Septic Shock Pragmatic Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-02-01
Completion:: 2026-02-17

Conditions

Septic Shock

Interventions

DRUG
OTHER

No Results Yet

NCT06215326 | RECRUITING | NA

100 participants

Short-term Effects of Preoperative Exercise in Moderate-to-high Perioperative Risk Lung Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-01-23
Completion:: 2026-12-31

Conditions

Lung Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06210971 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Neoadjuvant Chemoradiation With Nal-IRI and Capecitabine Guided by UGT1A1 Status in Patients With Rectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-02-01
Completion:: 2025-09-30

Conditions

Rectal Cancer

Interventions

DRUG
RADIATION

No Results Yet

NCT06189755 | RECRUITING

500 participants

MicroRNAs as Biomarkers for Obstructive Sleep Apnea

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-04-01
Completion:: 2027-11-01

Conditions

Obstructive Sleep Apnea

Interventions

DEVICE

No Results Yet

NCT06177067 | RECRUITING | PHASE1

24 participants

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-04-19
Completion:: 2026-10-31

Conditions

Refractory Acute Myeloid Leukemia
Relapsed Acute Myeloid Leukemia
Acute Leukemia of Ambiguous Lineage

Interventions

DRUG

No Results Yet

NCT06176079 | COMPLETED

44 participants

Hyperpolarized Pyruvate (13C) Magnetic Resonance Imaging In Patients With Fatty Liver Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-07-22
Completion:: 2025-08-28

Conditions

Non-Alcoholic Fatty Liver Disease
Non Alcoholic Fatty Liver
Non Alcoholic Steatohepatitis
NAFLD
NASH

Interventions

DRUG
PROCEDURE

No Results Yet

NCT06174701 | COMPLETED | NA

29 participants

Building Resilience for Surgical Recovery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-06-04
Completion:: 2026-04-30

Conditions

Psychosocial Functioning
Surgery
Older Adults
Physical Function
Postoperative Outcome
Depressive Symptoms

Interventions

BEHAVIORAL

No Results Yet

NCT06164730 | RECRUITING | PHASE1

85 participants

A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-04-30
Completion:: 2026-08-31

Conditions

Heterozygous Familial Hypercholesterolemia
Premature Coronary Heart Disease

Interventions

DRUG

No Results Yet

NCT06158841 | RECRUITING | PHASE3

380 participants

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-05-19
Completion:: 2027-12-31

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06140901 | RECRUITING | NA

450 participants

Bronchial Epithelium of Children With Post-infectious Bronchiolitis Obliterans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-12-04
Completion:: 2026-12-04

Conditions

Bronchiolitis Obliterans

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06139419 | COMPLETED | PHASE2

114 participants

The Impact of Thymosin α-1 on the Efficacy of Concurrent Chemoradiotherapy Followed by Immunotherpay Consolidation for Locally Advanced NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-07-25
Completion:: 2026-06-30

Conditions

Non-small Cell Lung Cancer

Interventions

RADIATION
DRUG

No Results Yet

NCT06128551 | RECRUITING | PHASE1/PHASE2

534 participants

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-11-14
Completion:: 2028-12-31

Conditions

Non-Small Cell Lung Cancer (NSCLC)
Colorectal Cancer
Pancreatic Ductal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT06127160 | COMPLETED | PHASE4

39 participants

Patient-Directed Antimicrobial Duration in Acute Uncomplicated Pyelonephritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-06-04
Completion:: 2025-08-29

Conditions

Pyelonephritis Acute

Interventions

DRUG

Results Available

NCT06124976 | RECRUITING | PHASE2/PHASE3

70 participants

Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-06-19
Completion:: 2028-04-30

Conditions

Urothelial Carcinoma of the Renal Pelvis and Ureter
Transitional Cell Cancer of the Renal Pelvis and Ureter

Interventions

DRUG

No Results Yet

NCT06124118 | WITHDRAWN | PHASE1

0 participants

Tumor Treating Fields for Locally Advanced NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-04-04
Completion:: 2026-11-15

Conditions

Non Small Cell Lung Cancer

Interventions

RADIATION
DEVICE
DRUG

No Results Yet

NCT06118515 | COMPLETED | PHASE1

3 participants

A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2025-02-19
Completion:: 2026-04-07

Conditions

Congenital Cytomegalovirus Infection

Interventions

DRUG

No Results Yet

NCT06102902 | SUSPENDED | PHASE1

30 participants

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-06-05
Completion:: 2027-01-30

Conditions

Metastatic Colorectal Adenocarcinoma
Recurrent Colorectal Adenocarcinoma
Refractory Colorectal Adenocarcinoma
Stage IV Colorectal Cancer AJCC v8

Interventions

PROCEDURE
BIOLOGICAL
DRUG

No Results Yet

NCT06100289 | RECRUITING | PHASE3

70 participants

A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2025-01-22
Completion:: 2028-05-16

Conditions

Ulcerative Colitis
Crohn's Disease

Interventions

DRUG

No Results Yet

NCT06096688 | RECRUITING

1120 participants

Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-05-29
Completion:: 2026-12-31

Conditions

Colorectal Cancer
Endometrial Cancer
Hereditary Cancer Syndromes

No Results Yet

NCT06089109 | RECRUITING | NA

2800 participants

Creating VIP Corps to Reduce Maternal Deaths

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-09-25
Completion:: 2026-09-29

Conditions

Maternal Morbidity and Mortality

Interventions

BEHAVIORAL

No Results Yet

NCT06081244 | RECRUITING | PHASE3

348 participants

NeoAdj. Therapy Comparing Sacituzumab Govitecan (SG) vs. SG+Pembrolizumab in Low-risk, Triple-neg. EBC (ADAPT-TN-III)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-10-10
Completion:: 2029-09-30

Conditions

Triple Negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT06067893 | ENROLLING_BY_INVITATION | PHASE4

160 participants

Low Dose Dexmedetomidine as a Postoperative Pain Adjunct

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-07-01
Completion:: 2027-07-31

Conditions

Spinal Fusion
Adolescent Idiopathic Scoliosis

Interventions

DRUG

No Results Yet

NCT06066138 | RECRUITING | PHASE1

30 participants

A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2025-11-04
Completion:: 2027-01-31

Conditions

Locally Advanced Alveolar Soft Part Sarcoma
Metastatic Alveolar Soft Part Sarcoma
Locally Advanced Non Small Cell Lung Cancer
Metastatic Non Small Cell Lung Cancer
Locally Advanced Small Cell Lung Cancer
Metastatic Small Cell Lung Cancer
Locally Advanced Hepatocellular Carcinoma
Metastatic Hepatocellular Carcinoma
Locally Advanced Melanoma
Metastatic Melanoma

Interventions

DRUG

No Results Yet

NCT06052332 | RECRUITING | NA

230 participants

Efficacy and Safety of Conventional Neoadjuvant Therapy Versus Total Neoadjuvant Therapy in Older Patients With Locally Advanced Rectal Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-02-07
Completion:: 2029-12-31

Conditions

Locally Advanced Rectal Cancer
Older People

Interventions

RADIATION
DRUG
PROCEDURE
COMBINATION_PRODUCT

No Results Yet

NCT06046833 | RECRUITING | NA

50 participants

Continuous Glucose Metrics in Patients With Gastroparesis in Type 1 or Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2024-01-08
Completion:: 2026-12-31

Conditions

Diabetes Mellitus, Type 2
Diabetes Mellitus, Type 1
Gastroparesis With Diabetes Mellitus

Interventions

OTHER
DEVICE

No Results Yet

NCT06039865 | COMPLETED | NA

50 participants

Chronic Care Management With Wearable Devices in Patients Prescribed Positive Airway Pressure Therapy (mPAP) Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2023-10-20
Completion:: 2025-01-21

Conditions

Obstructive Sleep Apnea

Interventions

BEHAVIORAL

Results Available