Clinical Trials

NCT04447521 | COMPLETED

1404 participants

Surveillance of Non-invasive Streptococcus Pneumoniae Infections in Belgium

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-03

Start Date:

2020-09-01

Completion:

2025-05-01

Conditions

• Pneumonia
• Otitis Media
• Sinusitis Bacterial

No Results Yet

NCT04391452 | COMPLETED | NA

121 participants

Dietary Supplement With Magnesium, Vitamins, Rhodiola and L-theanine Stressed Subjects: Randomized Study Versus Placebo (MAGRITTE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-07-01

Completion:

2021-06-01

Conditions

• Stress, Psychological

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04380311 | COMPLETED | NA

17 participants

Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-05-01

Completion:

2025-04-30

Conditions

• Heart Transplant Failure and Rejection

Interventions

• DEVICE

Results Available

NCT04375228 | ACTIVE_NOT_RECRUITING | PHASE2

7 participants

Study of Rituximab or Tocilizumab for Patients With Steroid-Dependent Immune-Related Adverse Events (irAEs)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-09-25

Completion:

2025-05-14

Conditions

• Immune-related Adverse Events
• Advanced Solid Tumor

Interventions

• DRUG

Results Available

NCT04369625 | COMPLETED | NA

406 participants

Children of Mentally Ill Parents-Network - CHIMPS-NET

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-01-01

Completion:

2023-12-31

Conditions

• Mental Health Issue

Interventions

• BEHAVIORAL

No Results Yet

NCT04368806 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

173 participants

A Phase 2b/3a Study to Evaluate the Efficacy and Safety of JointStem in Patients Diagnosed as Knee Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2021-05-26

Completion:

2027-08-06

Conditions

• Osteoarthritis, Knee

Interventions

• DRUG
• OTHER

No Results Yet

NCT04366128 | COMPLETED | NA

61 participants

Camrelizumab, Pegaspargase and Apatinib With Radiation Therapy for Stage IE/IIE ENKTL

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-04-25

Completion:

2024-12-30

Conditions

• Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type

Interventions

• DRUG

No Results Yet

NCT04360330 | RECRUITING | NA

18 participants

SABER Study for Selected Early Stage Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-08-05

Completion:

2027-05-31

Conditions

• Breast Cancer
• Early-stage Breast Cancer

Interventions

• RADIATION

No Results Yet

NCT04322864 | COMPLETED | NA

184 participants

Telerehabilitation Intervention for Individuals With Shoulder Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2021-10-01

Completion:

2024-10-01

Conditions

• Shoulder Pain
• Musculoskeletal Diseases

Interventions

• OTHER

No Results Yet

NCT04320888 | ACTIVE_NOT_RECRUITING | PHASE2

1 participants

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2021-05-03

Completion:

2024-09-30

Conditions

• Hematopoietic and Lymphatic System Neoplasm
• Recurrent Ependymoma
• Recurrent Ewing Sarcoma
• Recurrent Hepatoblastoma
• Recurrent Histiocytic and Dendritic Cell Neoplasm
• Recurrent Langerhans Cell Histiocytosis
• Recurrent Lymphoma
• Recurrent Malignant Germ Cell Tumor
• Recurrent Malignant Glioma
• Recurrent Malignant Solid Neoplasm
• Recurrent Medulloblastoma
• Recurrent Neuroblastoma
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Osteosarcoma
• Recurrent Peripheral Primitive Neuroectodermal Tumor
• Recurrent Rhabdoid Tumor
• Recurrent Rhabdomyosarcoma
• Recurrent Soft Tissue Sarcoma
• Recurrent WHO Grade 2 Glioma
• Refractory Ependymoma
• Refractory Ewing Sarcoma
• Refractory Hepatoblastoma
• Refractory Histiocytic and Dendritic Cell Neoplasm
• Refractory Langerhans Cell Histiocytosis
• Refractory Lymphoma
• Refractory Malignant Germ Cell Tumor
• Refractory Malignant Glioma
• Refractory Malignant Solid Neoplasm
• Refractory Medulloblastoma
• Refractory Neuroblastoma
• Refractory Non-Hodgkin Lymphoma
• Refractory Osteosarcoma
• Refractory Peripheral Primitive Neuroectodermal Tumor
• Refractory Rhabdoid Tumor
• Refractory Rhabdomyosarcoma
• Refractory Soft Tissue Sarcoma
• Refractory WHO Grade 2 Glioma
• Wilms Tumor

Interventions

• PROCEDURE
• DRUG

Results Available

NCT04307030 | COMPLETED

9370 participants

Study on AI Recognition System Of Heart Sound In Congenital Heart Disease Screening

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-03

Start Date:

2020-07-01

Completion:

2024-05-01

Conditions

• Congenital Heart Disease in Children

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04302272 | RECRUITING

150 participants

STRIVE Post-Market Registry Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-03

Start Date:

2021-10-09

Completion:

2026-12-31

Conditions

• Emphysema

Interventions

• DEVICE

No Results Yet

NCT04284787 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2021-02-16

Completion:

2023-06-05

Conditions

• Acute Myeloid Leukemia
• Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
• Acute Myeloid Leukemia Post Cytotoxic Therapy
• Secondary Acute Myeloid Leukemia

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL

Results Available

NCT04274244 | COMPLETED | PHASE4

53 participants

Comparison of Clinical and Radiographic Parameters in the Application of Cross-linked Hyaluronic Acid 1.8% and Enamel Matrix Derivative in Periodontal Regeneration.

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-03-01

Completion:

2024-09-30

Conditions

• Chronic Periodontitis
• Periodontal Bone Loss

Interventions

• DRUG

No Results Yet

NCT04270474 | COMPLETED | NA

344 participants

Reducing Risk of Dementia Through Deprescribing

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-07-20

Completion:

2026-07-29

Conditions

• Dementia
• Alzheimer Disease, Late Onset

Interventions

• OTHER

No Results Yet

NCT04263831 | RECRUITING | PHASE1/PHASE2

30 participants

Low Dose IL-2 for the Treatment of Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2021-03-11

Completion:

2027-06-30

Conditions

• Crohn Disease

Interventions

• DRUG

No Results Yet

NCT04257227 | COMPLETED | NA

13 participants

Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced Illness

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-11-02

Completion:

2024-03-14

Conditions

• Depressive Symptoms
• Depression, Anxiety
• Psychological Distress
• Terminal Illness

Interventions

• DEVICE

No Results Yet

NCT04250844 | ACTIVE_NOT_RECRUITING

100 participants

Use of Intrapyloric Botulinum Injections in Children

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-03

Start Date:

2020-03-10

Completion:

2027-05-31

Conditions

• Vomiting
• Feeding Disorders
• Gastroparesis

No Results Yet

NCT04197141 | ACTIVE_NOT_RECRUITING | PHASE2

58 participants

Hypofractionated Whole-Pelvis Radiotherapy (WPRT) vs Conventionally-Fractionated WPRT in Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-02-07

Completion:

2026-09-30

Conditions

• Prostate Cancer

Interventions

• RADIATION

No Results Yet

NCT04196374 | COMPLETED | NA

7603 participants

Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2021-06-09

Completion:

2025-05-30

Conditions

• Seemingly Healthy
• Genetic Predisposition to Disease

Interventions

• GENETIC

Results Available

NCT04176198 | RECRUITING | PHASE1/PHASE2

240 participants

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2019-12-16

Completion:

2027-04-30

Conditions

• Myelofibrosis

Interventions

• DRUG

No Results Yet

NCT04107545 | COMPLETED | NA

48 participants

Metabolic, Functional and Nutritional Responses to Weight Cycling in Athletes: The WAVE Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2021-05-03

Completion:

2023-12-12

Conditions

• Athletes

Interventions

• BEHAVIORAL

No Results Yet

NCT04099797 | RECRUITING | PHASE1

56 participants

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-02-03

Completion:

2027-02-28

Conditions

• Diffuse Intrinsic Pontine Glioma
• High Grade Glioma
• Embryonal Tumor
• Ependymal Tumor

Interventions

• GENETIC

No Results Yet

NCT04070534 | COMPLETED | NA

95 participants

PALS for Pap Smear Follow up

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2019-08-22

Completion:

2026-01-31

Conditions

• Health Knowledge, Attitudes, Practice

Interventions

• OTHER

No Results Yet

NCT04016402 | COMPLETED

42 participants

Imaging to Improve Brain Stimulation

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-03

Start Date:

2019-10-24

Completion:

2024-09-30

Conditions

• Depressive Disorder

Interventions

• DEVICE

No Results Yet

NCT04004572 | COMPLETED | PHASE2

37 participants

Sintilimab, Pegaspargase and Anlotinib for Stage IV Natural Killer /T-cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2019-07-01

Completion:

2024-12-30

Conditions

• Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type

Interventions

• DRUG

No Results Yet

NCT04004169 | RECRUITING | NA

12 participants

Closed-Loop Deep Brain Stimulation for Major Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2019-07-18

Completion:

2030-06-28

Conditions

• Major Depressive Disorder

Interventions

• DEVICE

No Results Yet

NCT03981432 | COMPLETED | NA

34 participants

Energy Intake, Exercise and Constitutional Leanness

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2021-04-16

Completion:

2023-11-14

Conditions

• Anorexia Nervosa
• Constitutional Leanness

Interventions

• BEHAVIORAL

No Results Yet

NCT03972072 | COMPLETED | NA

49 participants

MRI - Guided Adaptive RadioTHerapy for Reducing XerostomiA in Head and Neck Cancer (MARTHA-trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2019-10-15

Completion:

2025-05-21

Conditions

• Head and Neck Cancer
• Xerostomia Due to Radiotherapy

Interventions

• OTHER
• DIAGNOSTIC_TEST

No Results Yet

NCT03967782 | COMPLETED | NA

17 participants

Effect of the Exercise-meal Timing on Energy Intake and Appetite in Adolescents With Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2019-08-31

Completion:

2019-09-29

Conditions

• Pediatric obésity

Interventions

• BEHAVIORAL

No Results Yet

NCT03966027 | RECRUITING | NA

25 participants

Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-08-01

Completion:

2027-06-15

Conditions

• Ankle Fractures

Interventions

• OTHER

No Results Yet

NCT03955952 | COMPLETED

91700 participants

Cardiovascular Outcomes in Bariatric Surgery Patients With Type 2 Diabetes

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-03

Start Date:

2019-06-05

Completion:

2019-07-12

Conditions

• Obesity
• Type2 Diabetes
• Bariatric Surgery Candidate

Interventions

• PROCEDURE

Results Available

NCT03941236 | COMPLETED | PHASE3

42 participants

Extension Trial Evaluating the Long-term Safety and Efficacy of Dasiglucagon in Children With Congenital Hyperinsulinism

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2019-05-02

Completion:

2025-01-28

Conditions

• Congenital Hyperinsulinism

Interventions

• DRUG

No Results Yet

NCT03920007 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

15 participants

Study of Subretinally Injected ATSN-101 Administered in Patients With Leber Congenital Amaurosis Caused by Biallelic Mutations in GUCY2D

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2019-10-22

Completion:

2023-05-19

Conditions

• Leber Congenital Amaurosis
• LCA
• LCA1

Interventions

• DRUG

Results Available

NCT03916146 | ACTIVE_NOT_RECRUITING | NA

295 participants

Behavioral Parent Training for Families With Deaf and Hard of Hearing Preschoolers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2021-06-17

Completion:

2024-10-14

Conditions

• Deafness
• Hearing Loss
• Parenting
• Child Behavior

Interventions

• BEHAVIORAL

Results Available

NCT03909347 | COMPLETED | NA

574 participants

PLAN: Dementia Literacy Education and Navigation for Korean Elders With Probable Dementia and Their Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2021-04-20

Completion:

2024-12-03

Conditions

• Dementia

Interventions

• BEHAVIORAL

Results Available

NCT03900689 | COMPLETED

100 participants

Social Determinants of Health in Glioblastoma Population

Study Type:

OBSERVATIONAL

Last Updated:

2026-08-03

Start Date:

2019-05-22

Completion:

2022-03-27

Conditions

• Glioma
• Astrocytoma
• Oligodendroglioma
• Ependymoma
• Ganglioglioma
• Pleomorphic Xanthoastrocytoma

Interventions

• OTHER

No Results Yet

NCT03878095 | ACTIVE_NOT_RECRUITING | PHASE2

24 participants

Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2020-01-30

Completion:

2025-03-12

Conditions

• Malignant Solid Neoplasm
• Refractory Cholangiocarcinoma
• Refractory Malignant Solid Neoplasm

Interventions

• PROCEDURE
• DRUG

Results Available

NCT03869190 | TERMINATED | PHASE1/PHASE2

272 participants

Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2019-06-01

Completion:

2025-10-08

Conditions

• Urothelial Carcinoma
• Bladder Cancer

Interventions

• DRUG

Results Available

NCT03868943 | TERMINATED | PHASE2

2 participants

Solriamfetol in Improving Sleep in Patients With Grade II-IV Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-08-03

Start Date:

2021-01-27

Completion:

2021-11-22

Conditions

• Glioma
• Glioblastoma

Interventions

• DRUG

Results Available