Clinical Trials

NCT04375228 | ACTIVE_NOT_RECRUITING | PHASE2

7 participants

Study of Rituximab or Tocilizumab for Patients With Steroid-Dependent Immune-Related Adverse Events (irAEs)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-09-25
Completion:: 2025-05-14

Conditions

Immune-related Adverse Events
Advanced Solid Tumor

Interventions

DRUG

Results Available

NCT04369625 | COMPLETED | NA

406 participants

Children of Mentally Ill Parents-Network - CHIMPS-NET

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-01-01
Completion:: 2023-12-31

Conditions

Mental Health Issue

Interventions

BEHAVIORAL

No Results Yet

NCT04368806 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

173 participants

A Phase 2b/3a Study to Evaluate the Efficacy and Safety of JointStem in Patients Diagnosed as Knee Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-05-26
Completion:: 2027-08-06

Conditions

Osteoarthritis, Knee

Interventions

DRUG
OTHER

No Results Yet

NCT04366128 | COMPLETED | NA

61 participants

Camrelizumab, Pegaspargase and Apatinib With Radiation Therapy for Stage IE/IIE ENKTL

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-04-25
Completion:: 2024-12-30

Conditions

Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type

Interventions

DRUG

No Results Yet

NCT04360330 | RECRUITING | NA

18 participants

SABER Study for Selected Early Stage Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-08-05
Completion:: 2027-05-31

Conditions

Breast Cancer
Early-stage Breast Cancer

Interventions

RADIATION

No Results Yet

NCT04322864 | COMPLETED | NA

184 participants

Telerehabilitation Intervention for Individuals With Shoulder Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-10-01
Completion:: 2024-10-01

Conditions

Shoulder Pain
Musculoskeletal Diseases

Interventions

OTHER

No Results Yet

NCT04320888 | ACTIVE_NOT_RECRUITING | PHASE2

1 participants

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-05-03
Completion:: 2024-09-30

Conditions

Hematopoietic and Lymphatic System Neoplasm
Recurrent Ependymoma
Recurrent Ewing Sarcoma
Recurrent Hepatoblastoma
Recurrent Histiocytic and Dendritic Cell Neoplasm
Recurrent Langerhans Cell Histiocytosis
Recurrent Lymphoma
Recurrent Malignant Germ Cell Tumor
Recurrent Malignant Glioma
Recurrent Malignant Solid Neoplasm
Recurrent Medulloblastoma
Recurrent Neuroblastoma
Recurrent Non-Hodgkin Lymphoma
Recurrent Osteosarcoma
Recurrent Peripheral Primitive Neuroectodermal Tumor
Recurrent Rhabdoid Tumor
Recurrent Rhabdomyosarcoma
Recurrent Soft Tissue Sarcoma
Recurrent WHO Grade 2 Glioma
Refractory Ependymoma
Refractory Ewing Sarcoma
Refractory Hepatoblastoma
Refractory Histiocytic and Dendritic Cell Neoplasm
Refractory Langerhans Cell Histiocytosis
Refractory Lymphoma
Refractory Malignant Germ Cell Tumor
Refractory Malignant Glioma
Refractory Malignant Solid Neoplasm
Refractory Medulloblastoma
Refractory Neuroblastoma
Refractory Non-Hodgkin Lymphoma
Refractory Osteosarcoma
Refractory Peripheral Primitive Neuroectodermal Tumor
Refractory Rhabdoid Tumor
Refractory Rhabdomyosarcoma
Refractory Soft Tissue Sarcoma
Refractory WHO Grade 2 Glioma
Wilms Tumor

Interventions

PROCEDURE
DRUG

Results Available

NCT04307030 | COMPLETED

9370 participants

Study on AI Recognition System Of Heart Sound In Congenital Heart Disease Screening

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-07-01
Completion:: 2024-05-01

Conditions

Congenital Heart Disease in Children

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04302272 | RECRUITING

150 participants

STRIVE Post-Market Registry Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-10-09
Completion:: 2026-12-31

Conditions

Emphysema

Interventions

DEVICE

No Results Yet

NCT04293224 | COMPLETED | NA

54 participants

Metabolic and Bio-behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2022-08-01
Completion:: 2026-07-30

Conditions

Obesity
Body Weight

Interventions

OTHER

No Results Yet

NCT04284787 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-02-16
Completion:: 2023-06-05

Conditions

Acute Myeloid Leukemia
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
Acute Myeloid Leukemia Post Cytotoxic Therapy
Secondary Acute Myeloid Leukemia

Interventions

DRUG
PROCEDURE
BIOLOGICAL

Results Available

NCT04274244 | COMPLETED | PHASE4

53 participants

Comparison of Clinical and Radiographic Parameters in the Application of Cross-linked Hyaluronic Acid 1.8% and Enamel Matrix Derivative in Periodontal Regeneration.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-03-01
Completion:: 2024-09-30

Conditions

Chronic Periodontitis
Periodontal Bone Loss

Interventions

DRUG

No Results Yet

NCT04270474 | COMPLETED | NA

344 participants

Reducing Risk of Dementia Through Deprescribing

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-07-20
Completion:: 2026-07-29

Conditions

Dementia
Alzheimer Disease, Late Onset

Interventions

OTHER

No Results Yet

NCT04263831 | RECRUITING | PHASE1/PHASE2

30 participants

Low Dose IL-2 for the Treatment of Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-03-11
Completion:: 2027-06-30

Conditions

Crohn Disease

Interventions

DRUG

No Results Yet

NCT04257227 | COMPLETED | NA

13 participants

Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced Illness

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-11-02
Completion:: 2024-03-14

Conditions

Depressive Symptoms
Depression, Anxiety
Psychological Distress
Terminal Illness

Interventions

DEVICE

No Results Yet

NCT04250844 | ACTIVE_NOT_RECRUITING

100 participants

Use of Intrapyloric Botulinum Injections in Children

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-03-10
Completion:: 2027-05-31

Conditions

Vomiting
Feeding Disorders
Gastroparesis

No Results Yet

NCT04197141 | ACTIVE_NOT_RECRUITING | PHASE2

58 participants

Hypofractionated Whole-Pelvis Radiotherapy (WPRT) vs Conventionally-Fractionated WPRT in Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-02-07
Completion:: 2026-09-30

Conditions

Prostate Cancer

Interventions

RADIATION

No Results Yet

NCT04196374 | COMPLETED | NA

7603 participants

Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-06-09
Completion:: 2025-05-30

Conditions

Seemingly Healthy
Genetic Predisposition to Disease

Interventions

GENETIC

Results Available

NCT04176198 | RECRUITING | PHASE1/PHASE2

240 participants

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-12-16
Completion:: 2027-04-30

Conditions

Myelofibrosis

Interventions

DRUG

No Results Yet

NCT04107545 | COMPLETED | NA

48 participants

Metabolic, Functional and Nutritional Responses to Weight Cycling in Athletes: The WAVE Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-05-03
Completion:: 2023-12-12

Conditions

Athletes

Interventions

BEHAVIORAL

No Results Yet

NCT04099797 | RECRUITING | PHASE1

56 participants

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-02-03
Completion:: 2027-02-28

Conditions

Diffuse Intrinsic Pontine Glioma
High Grade Glioma
Embryonal Tumor
Ependymal Tumor

Interventions

GENETIC

No Results Yet

NCT04070534 | COMPLETED | NA

95 participants

PALS for Pap Smear Follow up

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-08-22
Completion:: 2026-01-31

Conditions

Health Knowledge, Attitudes, Practice

Interventions

OTHER

No Results Yet

NCT04016402 | COMPLETED

42 participants

Imaging to Improve Brain Stimulation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-10-24
Completion:: 2024-09-30

Conditions

Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT04004572 | COMPLETED | PHASE2

37 participants

Sintilimab, Pegaspargase and Anlotinib for Stage IV Natural Killer /T-cell Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-07-01
Completion:: 2024-12-30

Conditions

Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type

Interventions

DRUG

No Results Yet

NCT04004169 | RECRUITING | NA

12 participants

Closed-Loop Deep Brain Stimulation for Major Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-07-18
Completion:: 2030-06-28

Conditions

Major Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT03981432 | COMPLETED | NA

34 participants

Energy Intake, Exercise and Constitutional Leanness

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-04-16
Completion:: 2023-11-14

Conditions

Anorexia Nervosa
Constitutional Leanness

Interventions

BEHAVIORAL

No Results Yet

NCT03972072 | COMPLETED | NA

49 participants

MRI - Guided Adaptive RadioTHerapy for Reducing XerostomiA in Head and Neck Cancer (MARTHA-trial)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-10-15
Completion:: 2025-05-21

Conditions

Head and Neck Cancer
Xerostomia Due to Radiotherapy

Interventions

OTHER
DIAGNOSTIC_TEST

No Results Yet

NCT03967782 | COMPLETED | NA

17 participants

Effect of the Exercise-meal Timing on Energy Intake and Appetite in Adolescents With Obesity

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-08-31
Completion:: 2019-09-29

Conditions

Pediatric obésity

Interventions

BEHAVIORAL

No Results Yet

NCT03966027 | RECRUITING | NA

25 participants

Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-08-01
Completion:: 2027-06-15

Conditions

Ankle Fractures

Interventions

OTHER

No Results Yet

NCT03955952 | COMPLETED

91700 participants

Cardiovascular Outcomes in Bariatric Surgery Patients With Type 2 Diabetes

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-06-05
Completion:: 2019-07-12

Conditions

Obesity
Type2 Diabetes
Bariatric Surgery Candidate

Interventions

PROCEDURE

Results Available

NCT03941236 | COMPLETED | PHASE3

42 participants

Extension Trial Evaluating the Long-term Safety and Efficacy of Dasiglucagon in Children With Congenital Hyperinsulinism

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-05-02
Completion:: 2025-01-28

Conditions

Congenital Hyperinsulinism

Interventions

DRUG

No Results Yet

NCT03920007 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

15 participants

Study of Subretinally Injected ATSN-101 Administered in Patients With Leber Congenital Amaurosis Caused by Biallelic Mutations in GUCY2D

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-10-22
Completion:: 2023-05-19

Conditions

Leber Congenital Amaurosis
LCA
LCA1

Interventions

DRUG

Results Available

NCT03916146 | ACTIVE_NOT_RECRUITING | NA

295 participants

Behavioral Parent Training for Families With Deaf and Hard of Hearing Preschoolers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-06-17
Completion:: 2024-10-14

Conditions

Deafness
Hearing Loss
Parenting
Child Behavior

Interventions

BEHAVIORAL

Results Available

NCT03909347 | COMPLETED | NA

574 participants

PLAN: Dementia Literacy Education and Navigation for Korean Elders With Probable Dementia and Their Caregivers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-04-20
Completion:: 2024-12-03

Conditions

Dementia

Interventions

BEHAVIORAL

Results Available

NCT03900689 | COMPLETED

100 participants

Social Determinants of Health in Glioblastoma Population

Study Type:: OBSERVATIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-05-22
Completion:: 2022-03-27

Conditions

Glioma
Astrocytoma
Oligodendroglioma
Ependymoma
Ganglioglioma
Pleomorphic Xanthoastrocytoma

Interventions

OTHER

No Results Yet

NCT03886246 | ACTIVE_NOT_RECRUITING | PHASE2

131 participants

Effisayil™ ON: A Study to Test Long-term Treatment With Spesolimab in People With Generalized Pustular Psoriasis Who Took Part in a Previous Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-05-29
Completion:: 2027-09-30

Conditions

Generalized Pustular Psoriasis

Interventions

DRUG

No Results Yet

NCT03878095 | ACTIVE_NOT_RECRUITING | PHASE2

24 participants

Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2020-01-30
Completion:: 2025-03-12

Conditions

Malignant Solid Neoplasm
Refractory Cholangiocarcinoma
Refractory Malignant Solid Neoplasm

Interventions

PROCEDURE
DRUG

Results Available

NCT03869190 | TERMINATED | PHASE1/PHASE2

272 participants

Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-06-01
Completion:: 2025-10-08

Conditions

Urothelial Carcinoma
Bladder Cancer

Interventions

DRUG

Results Available

NCT03868943 | TERMINATED | PHASE2

2 participants

Solriamfetol in Improving Sleep in Patients With Grade II-IV Glioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2021-01-27
Completion:: 2021-11-22

Conditions

Glioma
Glioblastoma

Interventions

DRUG

Results Available

NCT03861091 | COMPLETED | PHASE2

84 participants

Prophylactic Risedronate for Patients With Peripheral Lung Tumors Treated With SBRT

Study Type:: INTERVENTIONAL
Last Updated:: 2026-08-03
Start Date:: 2019-07-12
Completion:: 2022-03-02

Conditions

Lung Neoplasm

Interventions

DRUG

Results Available