Clinical Trials

NCT07512427 | RECRUITING | PHASE1/PHASE2

30 participants

Phase 1/2 Study of OPK-88006 in Healthy and Presumed MASH Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-07-24
Completion:: 2027-12-31

Conditions

MASH

Interventions

DRUG

No Results Yet

NCT07512128 | NOT_YET_RECRUITING | NA

185 participants

Study of the Shockwave Medical SkyRunner Carotid Intravascular Lithotripsy (IVL) System for the Treatment of Calcified Carotid Arteries Prior to Trans-Femoral Stenting (SKYWARD Trans-Femoral IDE [Investigational Device Exemption] Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-07-31
Completion:: 2027-12-31

Conditions

Carotid Artery Calcification
Carotid Artery Diseases

Interventions

DEVICE

No Results Yet

NCT07511166 | NOT_YET_RECRUITING

300 participants

A Study of Varipulse Catheter in Participants With Paroxysmal Atrial Fibrillation Under Optimized Sedation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-09-07
Completion:: 2028-07-28

Conditions

Atrial Fibrillation

No Results Yet

NCT07506980 | RECRUITING | NA

112 participants

Nurse Led Intervention on Self Care Adherence and Quality of Life

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-03-30
Completion:: 2026-09-30

Conditions

Nurse Led Interventions
Patients on Hemodialysis
Self Care
Quality of Life
Interdialytic Weight Gain

Interventions

BEHAVIORAL

No Results Yet

NCT07501520 | COMPLETED | NA

51 participants

Effect of Low Histamine-Based Modified Mediterranean Diet in Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-06-15
Completion:: 2025-03-10

Conditions

Multiple Sclerosis (MS) - Relapsing-remitting
Mediterranean Diet

Interventions

BEHAVIORAL

No Results Yet

NCT07499232 | RECRUITING | PHASE3

530 participants

A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-04-21
Completion:: 2028-11-15

Conditions

Crohn Disease

Interventions

DRUG

No Results Yet

NCT07483827 | RECRUITING | PHASE1

39 participants

A Clinical Trial to Test the Safety, Tolerability, and How the Body Processes CPV-104 in Healthy People and Patients With C3-Glomerulopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-06-26
Completion:: 2026-11-30

Conditions

C3 Glomerulopathy (C3G)
Healthy Adult Participants

Interventions

DRUG

No Results Yet

NCT07478653 | NOT_YET_RECRUITING | NA

50 participants

MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-09-01
Completion:: 2028-07-31

Conditions

Obesity
Dental Care for Children

Interventions

PROCEDURE
BEHAVIORAL

No Results Yet

NCT07477275 | COMPLETED | NA

68 participants

Combination of Oral and Topical Whitening Agents for Reducing Skin Pigmentation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-12-01
Completion:: 2026-04-30

Conditions

Dark Spots

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT07476781 | RECRUITING | NA

60 participants

Exploring the Feasibility of Cerebrospinal Fluid (CSF) and Blood Plasma Liquid Biopsy in Patients With Metastatic Solid Tumours and Primary Central Nervous System (CNS) Tumours: A Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-12-12
Completion:: 2026-12-31

Conditions

Solid Tumor Malignancies
Brain Metastasases
Leptomeningeal Disease (LMD)
Central Nervous System

Interventions

PROCEDURE

No Results Yet

NCT07476222 | RECRUITING

600 participants

Predictors of Androgen Status Decline in Middle-Aged Men

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-06-01
Completion:: 2027-12-31

Conditions

Testosterone Deficiency
Androgen Deficiency
Male Hypogonadism
Late-Onset Hypogonadism

Interventions

OTHER

No Results Yet

NCT07469891 | RECRUITING | PHASE1

100 participants

A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-04-29
Completion:: 2028-04-30

Conditions

Polycythemia Vera (PV)
Myelofibrosis (MF)
Myeloproliferative Neoplasms (MPNs)
Post-Polycythemia Vera Myelofibrosis
Post-Essential Thrombocythemia Myelofibrosis
Primary Myelofibrosis (PMF)

Interventions

DRUG

No Results Yet

NCT07463079 | COMPLETED | NA

15 participants

Clinical Evaluation of a Soothing Moisturizing Lotion in Individuals With Atopic Eczema

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-02-01
Completion:: 2026-06-30

Conditions

Eczema

Interventions

OTHER

No Results Yet

NCT07456059 | COMPLETED | PHASE1

24 participants

A Study to Evaluate EDG-7500 in Caucasian and Japanese Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-03-10
Completion:: 2026-06-01

Conditions

Healthy Adult Participants

Interventions

DRUG

No Results Yet

NCT07448077 | RECRUITING | PHASE2

128 participants

Short-course Radiotherapy in TNT Combined With Enlonstobart for pMMR LARC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-03-01
Completion:: 2026-03-01

Conditions

Efficacy and Safety of Short-course Radiotherapy in Total Neoadjuvant Therapy Combined With Enlonstobart for pMMR Locally Advanced Rectal Cancer

Interventions

DRUG

No Results Yet

NCT07448038 | RECRUITING | PHASE2

162 participants

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-06-05
Completion:: 2028-01-31

Conditions

Atherosclerosis

Interventions

DRUG

No Results Yet

NCT07442045 | RECRUITING

150 participants

Real-World Effectiveness and Safety of Upadacitinib Plus Vedolizumab vs Upadacitinib Monotherapy During Induction in Moderate-to-Severe Ulcerative Colitis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2023-01-01
Completion:: 2025-11-30

Conditions

Ulcerative Colitis (UC)

Interventions

DRUG

No Results Yet

NCT07438496 | RECRUITING | PHASE3

600 participants

A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-03-05
Completion:: 2028-12-06

Conditions

Lupus Erythematosus, Systemic

Interventions

DRUG

No Results Yet

NCT07434635 | RECRUITING | PHASE4

62 participants

APPRAISE: Assessment of Pain and Posterior Synechiae Reduction With Atropine, an Investigation of Post-Surgical Eyes

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-03-10
Completion:: 2028-02-29

Conditions

Eye Disorders

Interventions

DRUG

No Results Yet

NCT07419841 | RECRUITING | PHASE1

70 participants

A Phase 1 Study of the Safety and Tolerability of CTX-10726

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-05-28
Completion:: 2028-04-01

Conditions

Gastroesophageal Cancer (GC)
Hepatocellular Carcinoma (HCC)
Endometrial Cancer
Renal Cell Carcinoma (RCC)

Interventions

DRUG

No Results Yet

NCT07404982 | RECRUITING | PHASE2

24 participants

Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-03-19
Completion:: 2026-12-31

Conditions

Joint Replacement Surgery

Interventions

DRUG

No Results Yet

NCT07404943 | COMPLETED | NA

70 participants

The Effect of Telenursing on Functionality and Treatment Adherence in Bipolar Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-12-01
Completion:: 2025-09-01

Conditions

Bi-Polar Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT07403929 | RECRUITING | NA

45 participants

The Effect of Fermented Grape Juice Consumption on Fibromyalgia Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-03-15
Completion:: 2026-12-15

Conditions

Fibromyalgia
Fibromyalgia (FM)
Fibromyalgia Syndrome, Primary

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07402343 | RECRUITING | PHASE2

35 participants

Tarlatamab for SCLC Brain Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-08-31
Completion:: 2029-02-28

Conditions

Small Cell Lung Cancer
Brain Metastases, Adult

Interventions

DRUG

No Results Yet

NCT07396298 | NOT_YET_RECRUITING | NA

304 participants

The Existential Cognitive Intervention to Enhance Positive Aspect of Caregiving (EXCITE-PAC) in a Dementia Context

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-09-15
Completion:: 2027-06-30

Conditions

Dementia Caregiver

Interventions

OTHER

No Results Yet

NCT07396129 | NOT_YET_RECRUITING | PHASE1/PHASE2

30 participants

Assessing the Efficacy of a High-Dose Lidocaine-Tetracaine Cream for the Treatment of Peripheral Neuropathic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-08-20
Completion:: 2026-12-01

Conditions

Neuropathic Chronic Pain

Interventions

DRUG

No Results Yet

NCT07394049 | NOT_YET_RECRUITING

3408 participants

A Prospective Multicenter Cohort Study of Contemporary Menopausal Hormone Therapy and Cardiovascular Outcomes

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-08-01
Completion:: 2041-03-31

Conditions

Hormone Replacement Therapy
Cardiovascular Diseases
Hormone Replacement Therapy, Post-Menopausal
Menopause

No Results Yet

NCT07387471 | ACTIVE_NOT_RECRUITING | PHASE2

16 participants

Study to Assess Change in Disease Activity of Oral Venetoclax in Adult Participants With Recurring Relapsed or Refractory (R/R) Waldenström Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-03-17
Completion:: 2028-07-31

Conditions

Waldenstrom Macroglobulinemia
Lymphoplasmacytic Lymphoma

Interventions

DRUG

No Results Yet

NCT07383272 | NOT_YET_RECRUITING | NA

20 participants

We Need to FEED: Facilitating Enteral Education for Discharge

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-08-30
Completion:: 2027-03-31

Conditions

Enteral Nutrition Feeding

Interventions

OTHER

No Results Yet

NCT07377526 | SUSPENDED | PHASE1/PHASE2

37 participants

TROP2 CAREngineered Cord Blood-Derived NK Cells + Belzutifan In Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-05-26
Completion:: 2028-03-01

Conditions

Pancreatic Cancer

Interventions

DRUG

No Results Yet

NCT07367100 | RECRUITING | NA

74 participants

A Pivotal Study Evaluating Safety and Effectiveness of Adaptative Tip Catheter in Patients With Acute Ischemic Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-02-02
Completion:: 2027-04-30

Conditions

Ischemic Stroke

Interventions

PROCEDURE

No Results Yet

NCT07363590 | RECRUITING | PHASE1

21 participants

A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-02-19
Completion:: 2029-07-16

Conditions

Systemic Lupus Erythematosus
Rheumatoid Arthritis

Interventions

BIOLOGICAL

No Results Yet

NCT07355166 | NOT_YET_RECRUITING | PHASE4

140 participants

Suzetrigine Versus Usual-care Opioids for Postop Pain in Sports

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-09-30
Completion:: 2027-01-31

Conditions

Postoperative Pain Management

Interventions

DRUG

No Results Yet

NCT07350993 | COMPLETED | NA

78 participants

Effect of Music on Dental Anxiety in Children: Turkish Validation of the CEDAM

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2024-04-22
Completion:: 2024-12-01

Conditions

Dental Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT07345832 | RECRUITING | NA

200 participants

The Effect of Volunteer-Engaged Lifestyle Optimisation Via ICOPE on Sarcopenia in Older Adults (VELO-S)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-02-01
Completion:: 2027-03-30

Conditions

Sarcopenia
Sarcopenia in Elderly
Fall Prevention in Healthy Aging
Frailty Syndrome
Malnutrition Elderly
Frailty

Interventions

BEHAVIORAL

No Results Yet

NCT07340541 | RECRUITING | PHASE2

700 participants

Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-02-16
Completion:: 2031-06-02

Conditions

Breast Cancer
Metastatic Breast Cancer
Triple Negative Breast Cancer
Estrogen-receptor-positive Breast Cancer
Hormone Receptor Negative Breast Carcinoma

Interventions

DRUG

No Results Yet

NCT07336238 | ACTIVE_NOT_RECRUITING | PHASE2

18 participants

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-05-19
Completion:: 2026-12-01

Conditions

Anxiety
Depression
Hematopoietic and Lymphatic System Neoplasm
Metastatic Malignant Solid Neoplasm

Interventions

BEHAVIORAL
DRUG
OTHER

No Results Yet

NCT07335601 | RECRUITING | PHASE2

120 participants

Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-12-29
Completion:: 2028-08-31

Conditions

MASH - Metabolic Dysfunction-Associated Steatohepatitis

Interventions

DRUG

No Results Yet

NCT07334964 | COMPLETED | NA

21 participants

Ultrasound-Guided Carpal Tunnel Infiltration: Comparison Between the Manual Method and a Robot-Assisted Method

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2025-11-25
Completion:: 2026-07-15

Conditions

Carpal Tunnel Syndrome

Interventions

PROCEDURE

No Results Yet

NCT07324616 | COMPLETED | PHASE1

25 participants

A Study to Evaluate EDG-7500 in Adults With Hepatic Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-31
Start Date:: 2026-01-26
Completion:: 2026-04-07

Conditions

Hepatic Impairment (HI)

Interventions

DRUG

No Results Yet