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MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease

NCT07478653 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2026-03-27

No results posted yet for this study

Summary

The goal of this clinical trial is to assess whether adjunctive dental cleaning can enhance the effects of semaglutide in children with obesity. The main question\[s\] it aims to answer \[is/are\]:

if dental cleaning will improve both oral health and metabolic outcomes beyond the effects of semaglutide alone.

Participants will receive either dental cleaning and oral hygiene instruction or oral hygiene instruction alone.

Conditions

Interventions

PROCEDURE

Dental Cleaning and Oral Hygiene Instruction (OHI)

Participants receive dental cleaning and oral hygiene instruction (OHI) and oral health assessments at baseline (prior to initiating weight-loss medication), 6 months (±2 weeks), and 12 months (±1 month) post-enrollment.

BEHAVIORAL

Oral Hygiene Instruction (OHI)

Participants will receive standard oral health care, including instructions on how to care for their teeth (OHI). Dental cleaning provided at 12 months.

Sponsors & Collaborators

  • Oelisoa Andriankaja

    lead OTHER

Principal Investigators

  • Oelisoa Andriankaja, DDS, PhD · University of Kentucky

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
12 Years
Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-01
Primary Completion
2028-07-31
Completion
2028-07-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07478653 on ClinicalTrials.gov