Clinical Trials

NCT06842355 | RECRUITING | PHASE2

92 participants

A Study of TYRA-300 in Children With Achondroplasia: BEACH301

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-03-04

Completion:

2030-01-31

Conditions

• Achondroplasia

Interventions

• DRUG

No Results Yet

NCT06828848 | RECRUITING | PHASE2

44 participants

A Study to Assess How Vaborem® is Taking up in the Body and Tolerated in Paediatric Patients With Gram Negative Infections, Including But Not Restricted to Complicated Urinary Tract Infections

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-02-18

Completion:

2026-07-31

Conditions

• Gram Negative Infections

Interventions

• DRUG

No Results Yet

NCT06827704 | ACTIVE_NOT_RECRUITING | NA

96 participants

Physical Activity Targeting Metabolic Syndrome for Prevention of Breast Cancer in SAI Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-05-01

Completion:

2026-06-30

Conditions

• Metabolic Syndrome
• Breast Cancer Prevention
• Physical Activity

Interventions

• BEHAVIORAL

No Results Yet

NCT06820060 | ACTIVE_NOT_RECRUITING

1500 participants

Clinical Performance of QIAstat-Dx® Meningitis/Encephalitis (ME) Panel Plus

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2025-04-03

Completion:

2026-05-15

Conditions

• Meningitis
• Encephalitis Infection

No Results Yet

NCT06816511 | ENROLLING_BY_INVITATION | NA

10 participants

Preliminary Explorative Study of Magnetic Resonance-Guided Focused Ultrasound Surgery in Refractory Obsessive-Compulsive Disorder Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-01-01

Completion:

2027-07-12

Conditions

• Obsessive-Compulsive Disorder (OCD)

Interventions

• PROCEDURE

No Results Yet

NCT06811116 | RECRUITING | PHASE1/PHASE2

92 participants

Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-11-17

Completion:

2027-08-31

Conditions

• Advanced Hepatocellular Carcinoma
• Metastatic Hepatocellular Carcinoma
• Stage III Hepatocellular Carcinoma AJCC v8
• Stage IV Hepatocellular Carcinoma AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT06807424 | RECRUITING | PHASE3

750 participants

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-01-09

Completion:

2027-02-10

Conditions

• Arthritis, Psoriatic

Interventions

• DRUG

No Results Yet

NCT06806358 | COMPLETED | NA

200 participants

Clinical and Ultrasonographic Predictors of IUD Related Complications

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-02-01

Completion:

2026-05-12

Conditions

• IUCD Complication

Interventions

• DEVICE

No Results Yet

NCT06795048 | ACTIVE_NOT_RECRUITING | PHASE4

274 participants

A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-03-14

Completion:

2026-10-20

Conditions

• Neovascular Age-related Macular Degeneration (nAMD)

Interventions

• DRUG

No Results Yet

NCT06791044 | RECRUITING | NA

120 participants

25(OH)-Vitamin D and Its Association With Structural and Functional Parameters in Hospitalized Patients With Neurological Diseases

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-09-01

Completion:

2027-06-30

Conditions

• Vitamin D Insufficiency

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT06788509 | ENROLLING_BY_INVITATION | PHASE1

120 participants

A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-12-30

Completion:

2028-01-19

Conditions

• Leukemia, Myeloid, Acute
• Leukemia, Lymphocytic, Chronic, B-Cell
• Lymphoma, Non-Hodgkin
• Myelodysplastic Syndromes
• Neoplasms
• Solid Tumor, Adult
• Prostatic Neoplasms, Castration-Resistant

Interventions

• DRUG

No Results Yet

NCT06785012 | ACTIVE_NOT_RECRUITING | PHASE2

107 participants

A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-12-26

Completion:

2026-06-25

Conditions

• Depressive Disorder, Major

Interventions

• DRUG

No Results Yet

NCT06770023 | RECRUITING | PHASE1

4 participants

Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2026-12-11

Completion:

2027-12-31

Conditions

• Lung Transplant
• Pulmonary Hypertension

Interventions

• DEVICE

No Results Yet

NCT06768489 | RECRUITING | PHASE1

240 participants

A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide or in Combination With Pomalidomide for Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-12-04

Completion:

2029-01-02

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06750094 | RECRUITING | PHASE3

700 participants

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-12-12

Completion:

2027-12-15

Conditions

• Colorectal Neoplasms

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06741969 | ACTIVE_NOT_RECRUITING | PHASE3

655 participants

Nipocalimab in Moderate to Severe Sjogren's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-12-04

Completion:

2028-01-01

Conditions

• Sjogrens Syndrome

Interventions

• DRUG

No Results Yet

NCT06735014 | RECRUITING

90 participants

Multicenter ALS Imaging Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2024-09-15

Completion:

2027-08-31

Conditions

• Amyotrophic Lateral Sclerosis
• ALS

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06729333 | COMPLETED

4841 participants

A Multicenter and Prospective Study of Screening Retinopathy of Prematurity in China

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2024-12-03

Completion:

2026-05-17

Conditions

• Premature Birth of Newborn
• Retinopathy of Prematurity (ROP)
• Low Birthweight Infant

No Results Yet

NCT06725277 | RECRUITING

450 participants

The OBSERVE Protocol

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2024-01-21

Completion:

2029-12-31

Conditions

• Major Depression Disorder

Interventions

• DRUG

No Results Yet

NCT06713616 | RECRUITING | PHASE3

400 participants

PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-01-27

Completion:

2030-12-31

Conditions

• Depression

Interventions

• DRUG

No Results Yet

NCT06709521 | COMPLETED | PHASE4

161 participants

Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-02-12

Completion:

2026-07-02

Conditions

• Bacterial Infection

Interventions

• DRUG

No Results Yet

NCT06708897 | RECRUITING | PHASE1

84 participants

A Study of Lonitoclax (ZE50-0134) in Relapsed or Refractory B-cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-04-08

Completion:

2028-01-31

Conditions

• CLL / SLL
• CLL (Chronic Lymphocytic Leukemia)
• SLL (Small Lymphocytic Lymphoma)
• Marginal Zone Lymphoma(MZL)
• Lymphoplasmacytic Lymphoma/Waldenström Macroglobulinemia

Interventions

• DRUG

No Results Yet

NCT06706674 | RECRUITING | PHASE3

160 participants

Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-12-06

Completion:

2027-06-21

Conditions

• Irritability Associated With Autism Spectrum Disorder

Interventions

• DRUG

No Results Yet

NCT06703073 | RECRUITING | PHASE2

600 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-06-10

Completion:

2028-07-31

Conditions

• Acute Respiratory Distress Syndrome (ARDS)
• ARDS
• ARDS (Acute Respiratory Distress Syndrome)
• Acute Respiratory Distress Syndrome

Interventions

• DRUG

No Results Yet

NCT06701682 | RECRUITING | PHASE2

200 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-06-21

Completion:

2028-07-31

Conditions

• Acute Respiratory Distress Syndrome (ARDS)
• ARDS
• ARDS (Acute Respiratory Distress Syndrome)
• Acute Respiratory Distress Syndrome

Interventions

• DRUG

No Results Yet

NCT06701669 | RECRUITING | PHASE2

200 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-06-10

Completion:

2028-07-31

Conditions

• Acute Respiratory Distress Syndrome (ARDS)
• ARDS
• ARDS (Acute Respiratory Distress Syndrome)
• Acute Respiratory Distress Syndrome

Interventions

• DRUG

No Results Yet

NCT06701656 | RECRUITING | PHASE2

200 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-10-28

Completion:

2028-07-31

Conditions

• Acute Respiratory Distress Syndrome (ARDS)
• ARDS
• ARDS (Acute Respiratory Distress Syndrome)
• Acute Respiratory Distress Syndrome

Interventions

• DRUG

No Results Yet

NCT06693609 | COMPLETED | PHASE2

70 participants

Exploratory Safety and Efficacy of EMP-01 in Social Anxiety Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-05-08

Completion:

2025-12-10

Conditions

• Social Anxiety Disorder

Interventions

• DRUG

No Results Yet

NCT06690411 | COMPLETED | NA

40 participants

Comparison of Myofascial Release and Mulligan Concept Techniques in Patients With Cervicogenic Headache

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-11-13

Completion:

2026-02-01

Conditions

• Cervicogenic Headache
• Cervicogenic Headaches

Interventions

• OTHER

No Results Yet

NCT06690398 | RECRUITING | PHASE3

160 participants

Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-11-22

Completion:

2027-06-21

Conditions

• Irritability Associated With Autism Spectrum Disorder

Interventions

• DRUG

No Results Yet

NCT06687720 | COMPLETED | NA

18 participants

A Clinical Study to Determine the Safety and Efficacy of An Oral Probiotic Supplementation in the Management of Irritable Bowel Syndrome With Protein Digestion.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-11-30

Completion:

2024-11-30

Conditions

• Irritable Bowel Syndrome

Interventions

• OTHER

No Results Yet

NCT06677060 | RECRUITING | PHASE3

11300 participants

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-03-14

Completion:

2029-12-17

Conditions

• Heart Failure

Interventions

• DRUG
• OTHER

No Results Yet

NCT06667076 | RECRUITING | PHASE2

480 participants

A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-12-16

Completion:

2029-05-23

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

No Results Yet

NCT06664788 | RECRUITING | NA

108 participants

A Study of ETHIZIA Versus SURGICEL Original in Controlling Soft Tissue Bleeding During Open Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-04-16

Completion:

2026-09-28

Conditions

• Hemostasis
• Hemostatic Techniques

Interventions

• DEVICE

No Results Yet

NCT06663332 | RECRUITING | PHASE3

196 participants

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-10-29

Completion:

2031-12-12

Conditions

• Crohns Disease
• Colitis, Ulcerative
• Arthritis, Psoriatic
• Arthritis, Juvenile

Interventions

• DRUG

No Results Yet

NCT06662786 | RECRUITING | PHASE3

1000 participants

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-10-18

Completion:

2028-12-15

Conditions

• Colorectal Neoplasms

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT06662305 | RECRUITING | PHASE2

306 participants

Kick-Nic! Youth Quit Vaping App

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-01-07

Completion:

2029-08-31

Conditions

• Nicotine Vaping

Interventions

• BEHAVIORAL

No Results Yet

NCT06660563 | ACTIVE_NOT_RECRUITING | PHASE1

19 participants

A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-10-22

Completion:

2026-01-19

Conditions

• Lymphoma, Non-Hodgkin

Interventions

• DRUG

No Results Yet

NCT06654037 | RECRUITING | PHASE1

39 participants

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2025-04-18

Completion:

2027-04-01

Conditions

• Metastatic Microsatellite Stable Colorectal Carcinoma
• Refractory Microsatellite Stable Colorectal Carcinoma
• Stage IV Colorectal Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT06651567 | RECRUITING | PHASE2

320 participants

A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-10-22

Completion:

2027-12-28

Conditions

• Agitation Associated With Alzheimer's Dementia

Interventions

• DRUG

No Results Yet