Preliminary Explorative Study of Magnetic Resonance-Guided Focused Ultrasound Surgery in Refractory Obsessive-Compulsive Disorder Patients
NCT06816511 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2026-03-17
Summary
The goal of this clinical trial is to evaluate If magnetic resonance-guided focused ultrasound works to treat refractory obsessive-compulsive disorder in adults. The main questions it aims to answer are:
* What effectiveness does the magnetic resonance-guided focused ultrasound bring to the participants during study period?
* What side effects do the participant have when treated with magnetic resonance-guide focused ultrasound?
Participants will:
* Finish scales to evaluate participants' level of cognitive function, depression and Compulsiveness.
* Receive the treatment of magnetic resonance-guided focused ultrasound
* Take the fMRI brain scanning before and after the treatment
* Recovering
Conditions
- Obsessive-Compulsive Disorder (OCD)
Interventions
- PROCEDURE
-
magnetic resonance-guided focused ultrasound surgery, MRgFUS
Magnetic Resonance-Guided Focused Ultrasound Surgery The clinical symptoms, brain imaging, and cognitive function status were followed up for 2 years before and after surgery.
Sponsors & Collaborators
-
National Taiwan University Hospital
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-01-01
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- Taiwan
Study Locations
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