Clinical Trials

NCT05956886 | COMPLETED | NA

26 participants

Sleep Chatbot Intervention for Emerging Black/African American Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-09-04

Completion:

2025-02-05

Conditions

• Sleep Deprivation
• Insomnia
• Metabolic Syndrome

Interventions

• BEHAVIORAL

Results Available

NCT05956626 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

51 participants

A Phase 2/3 Trial to Assess the Efficacy and Safety of OCU410ST for Stargardt Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-08-25

Completion:

2026-09-28

Conditions

• Stargardt Disease

Interventions

• DRUG

No Results Yet

NCT05947500 | ACTIVE_NOT_RECRUITING | PHASE2

50 participants

Testing the Combination of Two Anticancer Drugs M1774 (Tuvusertib) and Avelumab to Evaluate Their Safety and Effectiveness in Treating Merkel Cell Skin Cancer, MATRiX Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-05-21

Completion:

2028-01-01

Conditions

• Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8
• Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8
• Locally Advanced Merkel Cell Carcinoma
• Metastatic Merkel Cell Carcinoma
• Refractory Merkel Cell Carcinoma
• Unresectable Merkel Cell Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05913687 | ACTIVE_NOT_RECRUITING

315 participants

Automated Imaging Differentiation of Parkinsonism

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2021-07-22

Completion:

2027-03-31

Conditions

• Parkinson Disease
• Multiple System Atrophy, Parkinson Variant
• Progressive Supranuclear Palsy

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05901649 | COMPLETED

505 participants

A Study for the Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With Androgen Deprivation Therapy (ADT) Plus Apalutamide or Enzalutamide

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2023-07-05

Completion:

2026-06-16

Conditions

• Metastatic Hormone-sensitive Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT05898087 | COMPLETED | PHASE4

52 participants

Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-04-01

Completion:

2026-05-08

Conditions

• Macromastia
• Post-operative Pain

Interventions

• DRUG

No Results Yet

NCT05884853 | RECRUITING | NA

120 participants

The Plasticity of Social Brain Network in Adults With Autism Spectrum Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2021-01-01

Completion:

2027-12-31

Conditions

• Autism Spectrum Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05876754 | ACTIVE_NOT_RECRUITING | PHASE3

299 participants

An Early Access Study of Ivosidenib in Patients With a Pretreated Locally Advanced or Metastatic Cholangiocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-05-03

Completion:

2027-12-01

Conditions

• Cholangiocarcinoma

Interventions

• DRUG

No Results Yet

NCT05875376 | RECRUITING | NA

20 participants

Establish the Couple Intervention Program for Adults With Autism Spectrum Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-01-01

Completion:

2027-12-31

Conditions

• Autism Spectrum Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05875363 | RECRUITING

1000 participants

Neurodevelopmental Disorders in Youth With Criminal Behaviors

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2021-04-01

Completion:

2027-12-31

Conditions

• Attention Deficit Disorder With Hyperactivity
• Autistic Spectrum Disorder
• Conduct Disorders in Adolescence

Interventions

• OTHER

No Results Yet

NCT05857813 | RECRUITING | NA

120 participants

Social Skills Training Group Effectiveness in Adolescents With Autism Spectrum Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-01-01

Completion:

2027-07-12

Conditions

• Autism Spectrum Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT05838573 | COMPLETED | PHASE3

120 participants

Metformin Treatment on Cognitive Impairment of Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-05-08

Completion:

2026-06-08

Conditions

• Schizophrenia

Interventions

• DRUG
• OTHER

No Results Yet

NCT05833048 | RECRUITING | NA

75 participants

Rectus Sheath Block in Cardiac Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-07-29

Completion:

2026-10-30

Conditions

• Cardiac Disease
• Postoperative Pain

Interventions

• PROCEDURE

No Results Yet

NCT05828082 | ACTIVE_NOT_RECRUITING | PHASE2

20 participants

Testing the Effect of M1774 on Hard-to-Treat Refractory SPOP-mutant Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-10-16

Completion:

2027-01-01

Conditions

• Castration-Resistant Prostate Carcinoma
• Metastatic Castration-Resistant Prostate Carcinoma
• Refractory Prostate Carcinoma
• Stage IVB Prostate Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05828056 | RECRUITING

100 participants

Prediction on the Recurrence of Manic and Depressive Episodes in Bipolar Disorder

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2020-03-02

Completion:

2027-12-31

Conditions

• Bipolar Disorder
• Depressive Disorder

Interventions

• DEVICE

No Results Yet

NCT05810636 | ENROLLING_BY_INVITATION

200 participants

Hyperactivity Assessment in Children With Attention-deficit Hyperactivity Disorder

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-31

Start Date:

2022-02-16

Completion:

2026-12-31

Conditions

• Attention Deficit Disorder With Hyperactivity

Interventions

• DEVICE

No Results Yet

NCT05806606 | COMPLETED | NA

232 participants

Effect and Cost Effectiveness of a Dyadic Empowerment-based Heart Failure Management Program for Self-care

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-04-17

Completion:

2025-09-01

Conditions

• Heart Failure
• Self Care
• Empowerment
• Transitional Care
• Disease Management

Interventions

• OTHER

No Results Yet

NCT05802329 | RECRUITING | PHASE1

24 participants

Phase I Study to Assess the Safety and Efficacy of OCU200 for Center-Involved Diabetic Macular Edema (DME)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-01-13

Completion:

2026-07-31

Conditions

• Center Involved Diabetic Macular Edema
• Diabetic Macular Edema

Interventions

• DRUG

No Results Yet

NCT05801185 | ENROLLING_BY_INVITATION | NA

20 participants

Single Nuclei Sequencing in Human Skeletal Muscle After Unloading

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-03-05

Completion:

2026-07-31

Conditions

• Unilateral Lower Limb Suspension

Interventions

• OTHER

No Results Yet

NCT05794555 | COMPLETED | PHASE3

233 participants

LiveSMART Trial to Prevent Falls in Patients With Cirrhosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-06-13

Completion:

2025-03-07

Conditions

• Cirrhosis, Liver
• Portal Hypertension

Interventions

• BEHAVIORAL
• DRUG

Results Available

NCT05759923 | RECRUITING | PHASE1

40 participants

First-in-human Phase I Study to Evaluate Safety, Tolerability and Antineoplastic Activity of OATD-02 in Patients With Selected Advanced and/or Metastatic Solid Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-01-26

Completion:

2027-03-31

Conditions

• Advanced Ovarian Carcinoma
• Advanced Renal Cell Carcinoma
• Advanced Pancreatic Carcinoma
• Advanced Colorectal Carcinoma
• Metastatic Pancreatic Carcinoma
• Metastatic Colorectal Carcinoma
• Metastatic Renal Cell Carcinoma
• Metastatic Ovarian Carcinoma

Interventions

• DRUG

No Results Yet

NCT05742165 | COMPLETED | NA

29 participants

Time Restricted Eating for Weight Loss Maintenance

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-07-17

Completion:

2025-01-06

Conditions

• Obesity

Interventions

• BEHAVIORAL

Results Available

NCT05724108 | ACTIVE_NOT_RECRUITING | PHASE2

94 participants

Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-08-30

Completion:

2026-12-09

Conditions

• Metastatic Neuroendocrine Tumor

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05715255 | ACTIVE_NOT_RECRUITING | NA

400 participants

Adaptive Symptom Self-Management Immunotherapy Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-05-08

Completion:

2027-04-30

Conditions

• Breast Cancer
• Colon Cancer
• Lung Cancer
• Skin Cancer
• Rectum Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05703854 | SUSPENDED | PHASE1/PHASE2

50 participants

Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-03-29

Completion:

2027-09-30

Conditions

• Advanced Renal Cell Carcinoma
• Advanced Mesothelioma
• Advanced Osteosarcoma

Interventions

• DRUG

No Results Yet

NCT05695391 | TERMINATED | PHASE3

2 participants

Safety and Efficacy of FVIIa to Prevent Excessive Bleeding in Hemophilia Patients With Inhibitors Undergoing Major Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-06-07

Completion:

2025-05-28

Conditions

• Hemophilia

Interventions

• BIOLOGICAL

Results Available

NCT05693571 | ACTIVE_NOT_RECRUITING | NA

48 participants

Engagement in CHildhood-Onset Systemic Lupus

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2024-12-05

Completion:

2027-02-28

Conditions

• Lupus Erythematosus, Systemic
• Depression

Interventions

• BEHAVIORAL

No Results Yet

NCT05691491 | RECRUITING | PHASE1/PHASE2

42 participants

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-09-28

Completion:

2027-03-01

Conditions

• Advanced Malignant Solid Neoplasm
• Advanced Microsatellite Stable Colorectal Carcinoma
• Hematopoietic and Lymphatic System Neoplasm
• Metastatic Malignant Solid Neoplasm
• Metastatic Microsatellite Stable Colorectal Carcinoma
• Stage III Colorectal Cancer AJCC v8
• Stage IV Colorectal Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05673551 | ENROLLING_BY_INVITATION | NA

220 participants

VR-PAT During Home Burn Dressings - Multisite

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-01-16

Completion:

2027-12-01

Conditions

• Burns
• Acute Pain
• Procedural Pain
• Injuries
• Pediatric ALL

Interventions

• OTHER

No Results Yet

NCT05673200 | SUSPENDED | PHASE1

32 participants

Testing the Addition of an Anti-cancer Drug, ASTX727 (Cedazuridine, Decitabine), to Chemotherapy (Paclitaxel) and Immunotherapy (Pembrolizumab) for Metastatic Triple-Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-09-25

Completion:

2027-02-23

Conditions

• Anatomic Stage III Breast Cancer AJCC v8
• Anatomic Stage IV Breast Cancer AJCC v8
• Metastatic Triple-Negative Breast Carcinoma
• Unresectable Triple-Negative Breast Carcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT05669989 | ENROLLING_BY_INVITATION | PHASE2

70 participants

International Treatment-extension Study in Adult Participants With Multiple Myeloma and Who Have Derived Clinical Benefit From Isatuximab

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-04-05

Completion:

2028-11-30

Conditions

• Plasma Cell Myeloma

Interventions

• DRUG

No Results Yet

NCT05669664 | ACTIVE_NOT_RECRUITING | PHASE2

21 participants

Testing the Anti-cancer Drug Darolutamide in Patients With Testosterone-Driven Salivary Gland Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-07-20

Completion:

2026-11-30

Conditions

• Locally Advanced Salivary Gland Carcinoma
• Metastatic Salivary Gland Carcinoma
• Recurrent Salivary Gland Carcinoma
• Unresectable Salivary Gland Carcinoma

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT05663866 | ACTIVE_NOT_RECRUITING | PHASE2

68 participants

Premedication to Reduce Amivantamab Associated Infusion Related Reactions

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-05-18

Completion:

2024-03-29

Conditions

• Carcinoma, Non-Small-Cell Lung

Interventions

• DRUG

Results Available

NCT05625659 | RECRUITING | NA

2032 participants

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-03-24

Completion:

2027-07-31

Conditions

• Breast Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05610059 | COMPLETED | NA

200 participants

Improving Hypertension Medication Adherence for Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-11-02

Completion:

2025-03-14

Conditions

• Aging
• Medication Adherence
• Hypertension

Interventions

• OTHER

Results Available

NCT05609786 | COMPLETED | NA

440 participants

Dissemination and Implementation of a Web-based Relationship Safety App, myPlanKenya, for Women at Risk for Intimate Partner Violence in Nairobi, Kenya

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-06-22

Completion:

2024-12-31

Conditions

• Violence, Domestic
• Violence, Sexual
• Violence, Gender-Based

Interventions

• BEHAVIORAL

Results Available

NCT05589402 | COMPLETED | PHASE1

52 participants

Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2019-06-04

Completion:

2026-07-15

Conditions

• Spinal Cord Injuries
• Spine Disease
• Stroke

Interventions

• DRUG
• OTHER

No Results Yet

NCT05568264 | ACTIVE_NOT_RECRUITING | NA

222 participants

Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2022-10-01

Completion:

2026-12-31

Conditions

• Motor Delay
• Premature Birth
• Intraventricular Hemorrhage
• Hypoxic-Ischemic Encephalopathy
• Bronchopulmonary Dysplasia

Interventions

• OTHER

No Results Yet

NCT05567640 | RECRUITING | NA

1800 participants

Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-04-12

Completion:

2027-07-31

Conditions

• Anxiety Disorders and Symptoms
• Depressive Symptoms

Interventions

• BEHAVIORAL

No Results Yet

NCT05537857 | ACTIVE_NOT_RECRUITING | NA

66 participants

Racial/Ethnic in Calcium and Sodium Metabolism

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-31

Start Date:

2023-03-01

Completion:

2026-08-31

Conditions

• Healthy

Interventions

• OTHER

No Results Yet