Clinical Trials

NCT05739435 | ACTIVE_NOT_RECRUITING | PHASE2

165 participants

Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-01-17

Completion:

2027-12-01

Conditions

• Plaque Psoriasis

Interventions

• DRUG

No Results Yet

NCT05696483 | ACTIVE_NOT_RECRUITING | PHASE1

76 participants

Phase 1 Study of OLX-07010 in Healthy Adult and Elderly Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-01-20

Completion:

2026-05-11

Conditions

• Alzheimer Disease

Interventions

• DRUG

No Results Yet

NCT05692115 | NOT_YET_RECRUITING

90 participants

Ischemia and Inflammatory Markers Among Patients With Coronary Artery Ectasia

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-28

Start Date:

2026-08-31

Completion:

2026-08-31

Conditions

• Coronary Artery Ectasia

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05680012 | RECRUITING | NA

220 participants

Tissue Destruction and Healing in Celiac Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-07-14

Completion:

2027-05-01

Conditions

• Celiac Disease

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05666700 | ACTIVE_NOT_RECRUITING | PHASE1

10 participants

CAR-T Cell Therapy in RelApsed/Refractory Myeloma With ExtrameduLlary Disease - an in Vivo Imaging and Molecular Monitoring Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-12-08

Completion:

2027-01-31

Conditions

• Extramedullary Myeloma

Interventions

• BIOLOGICAL

No Results Yet

NCT05645692 | ACTIVE_NOT_RECRUITING | PHASE2

204 participants

A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-04-13

Completion:

2026-12-31

Conditions

• Urothelial Cancer

Interventions

• DRUG

No Results Yet

NCT05599789 | ACTIVE_NOT_RECRUITING | PHASE2

47 participants

Pembrolizumab in Combination With Plinabulin and Docetaxel For Metastatic NSCLC After ICIs (KeyPemls-004)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-02-01

Completion:

2025-05-21

Conditions

• Non Small Cell Lung Cancer Metastatic

Interventions

• DRUG

No Results Yet

NCT05588323 | RECRUITING | PHASE1/PHASE2

24 participants

Safety and Pharmacokinetics Study of Naldemedine in Paediatric Participants Receiving Opioids

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-01-04

Completion:

2028-06-15

Conditions

• Opioid-Induced Constipation (OIC)

Interventions

• DRUG

No Results Yet

NCT05574335 | TERMINATED | PHASE1/PHASE2

8 participants

Siplizumab in T1DM

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-05-18

Completion:

2025-05-14

Conditions

• Type 1 Diabetes Mellitus

Interventions

• DRUG

Results Available

NCT05521321 | COMPLETED | NA

658 participants

Feasibility and Acceptability of the Cannabis Awareness and Prevention Toolkit

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-10-01

Completion:

2025-05-16

Conditions

• Cannabis Use

Interventions

• BEHAVIORAL

Results Available

NCT05513742 | COMPLETED | PHASE2

49 participants

A Study of CTX-009 in Adult Patients With Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-12-08

Completion:

2025-05-15

Conditions

• Metastatic Colorectal Cancer
• Colon Cancer
• Rectal Cancer

Interventions

• DRUG

Results Available

NCT05505942 | ACTIVE_NOT_RECRUITING | NA

222 participants

Physical Activity for PLWH and Unhealthy Drinking

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-02-22

Completion:

2026-09-30

Conditions

• HIV
• Physical Inactivity
• Unhealthy Alcohol Use

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05503173 | ACTIVE_NOT_RECRUITING | NA

253 participants

Telehealth for Pain and Unhealthy Drinking Among PLWH

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-03-03

Completion:

2026-12-31

Conditions

• HIV
• Chronic Pain
• Unhealthy Alcohol Use

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05498662 | ACTIVE_NOT_RECRUITING

60 participants

An Observational Study of the T3 Pro Dental Implant System

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-28

Start Date:

2022-09-08

Completion:

2027-12-30

Conditions

• Tooth Loss

Interventions

• DEVICE

No Results Yet

NCT05463224 | ACTIVE_NOT_RECRUITING | PHASE2

150 participants

Lazertinib for NSCLC Harboring Activating EGFR Mutations in TKI naïve Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-01-04

Completion:

2026-12-01

Conditions

• NSCLC

Interventions

• DRUG

No Results Yet

NCT05420233 | ACTIVE_NOT_RECRUITING | NA

533 participants

The CROCO Study: CROhn's Disease COhort Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2021-08-01

Completion:

2030-07-31

Conditions

• Crohn Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05416853 | COMPLETED | NA

1200 participants

Radial Versus Femoral Access For Carotid Artery Stenting

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-07-04

Completion:

2025-03-24

Conditions

• Ischemic Stroke
• Carotid Stenosis
• Cerebral Revascularization
• Carotid Artery Diseases

Interventions

• PROCEDURE

No Results Yet

NCT05415072 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

66 participants

A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-07-04

Completion:

2027-10-01

Conditions

• Metastatic Uveal Melanoma

Interventions

• DRUG

No Results Yet

NCT05397496 | ACTIVE_NOT_RECRUITING | PHASE1

61 participants

Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-10-03

Completion:

2027-01-04

Conditions

• B-cell Non-Hodgkin Lymphoma (B-NHL)
• B-cell Acute Lymphoblastic Leukemia (B-ALL)

Interventions

• BIOLOGICAL

No Results Yet

NCT05373823 | RECRUITING | NA

385 participants

MySmartSkin Online Skin Self-exam Intervention for Melanoma Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-03-06

Completion:

2026-12-31

Conditions

• Melanoma

Interventions

• OTHER

No Results Yet

NCT05368038 | ENROLLING_BY_INVITATION

100000 participants

ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening Program

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-28

Start Date:

2021-05-10

Completion:

2029-08-31

Conditions

• Acid Sphingomyelinase Deficiency
• Ceroid Lipofuscinosis, Neuronal, 2
• Cerebrotendinous Xanthomatosis
• Fabry Disease
• GM1 Gangliosidosis
• Gaucher Disease
• Lysosomal Acid Lipase Deficiency
• Metachromatic Leukodystrophy
• Mucopolysaccharidosis II
• Mucopolysaccharidosis III-B
• Mucopolysaccharidosis IV A
• Mucopolysaccharidosis VI
• Mucopolysaccharidosis VII
• Niemann-Pick Disease, Type C

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT05362773 | ACTIVE_NOT_RECRUITING | PHASE1

130 participants

A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-07-13

Completion:

2026-11-30

Conditions

• Leukemia, Acute Myeloid
• Myelodysplastic Syndromes
• Classical Hodgkin Lymphoma
• Leukemia, B-cell
• Leukemia, Hairy Cell
• Mastocytosis, Aggressive Systemic
• Blastic Plasmacytoid Dendritic Cell Neoplasm
• Chronic Myeloid Leukemia

Interventions

• DRUG

No Results Yet

NCT05353452 | COMPLETED | NA

40 participants

Collaborative Care in Posttraumatic Epilepsy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-04-30

Completion:

2026-05-19

Conditions

• Epilepsy, Post-Traumatic

Interventions

• BEHAVIORAL

No Results Yet

NCT05351359 | COMPLETED | NA

343 participants

mHealth Intervention to Increase Physical Activity in Prediabetes and Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-04-25

Completion:

2025-05-08

Conditions

• Type 2 Diabetes
• PreDiabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT05343793 | COMPLETED | NA

70 participants

Stagewise Implementation-To-Target- Medications for Addiction Treatment (SITT-MAT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-03-14

Completion:

2026-06-30

Conditions

• Addiction, Opioid

Interventions

• OTHER

No Results Yet

NCT05341453 | COMPLETED | NA

21 participants

Equine-Assisted Physiotherapy for Spinal Muscular Atrophy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-04-22

Completion:

2024-09-25

Conditions

• Spinal Muscular Atrophy

Interventions

• PROCEDURE

No Results Yet

NCT05307432 | ENROLLING_BY_INVITATION | NA

2814 participants

Safety Planning Intervention Telehealth Service Model in Emergency Departments

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-05-01

Completion:

2027-01-31

Conditions

• Suicide
• Suicidal Ideation

Interventions

• BEHAVIORAL

No Results Yet

NCT05283356 | RECRUITING | PHASE4

1206 participants

Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-01-21

Completion:

2027-06-30

Conditions

• Severe Aortic Valve Stenosis
• Aortic Valve Stenosis
• Transcatheter Aortic Valve Replacement (TAVR)
• Transcatheter Aortic Valve Implantation (TAVI)

Interventions

• DRUG

No Results Yet

NCT05282901 | COMPLETED | PHASE2

51 participants

Efficacy and Safety of Pembrolizumab in Combination With Lenvatinib in Metastatic Uveal MElanoma Patients (PLUME)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-07-07

Completion:

2025-04-28

Conditions

• Metastatic Uveal Melanoma

Interventions

• DRUG

No Results Yet

NCT05263050 | RECRUITING | PHASE2

111 participants

Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-01-21

Completion:

2026-12-31

Conditions

• Metastatic Renal Cell Carcinoma
• Clear-cell Metastatic Renal Cell Carcinoma
• Neuroendocrine Tumors
• Carcinoid Tumor

Interventions

• DRUG

No Results Yet

NCT05238675 | COMPLETED | PHASE2

322 participants

A Study to Test Whether Different Doses of BI 1291583 Help People With Bronchiectasis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-04-28

Completion:

2024-05-01

Conditions

• Bronchiectasis

Interventions

• DRUG

No Results Yet

NCT05227326 | RECRUITING | PHASE1

92 participants

AOH1996 for the Treatment of Refractory Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-08-12

Completion:

2029-09-13

Conditions

• Refractory Malignant Solid Neoplasm
• Osteosarcoma
• Leiomyosarcomas
• Synovial Sarcomas
• Ovarian Cancer
• Non-Small Cell Lung Cancer
• Pancreatic Cancer

Interventions

• DRUG

No Results Yet

NCT05219799 | RECRUITING | EARLY_PHASE1

72 participants

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-03-14

Completion:

2027-07-30

Conditions

• Obesity
• Vasodilation
• Healthy

Interventions

• DRUG

No Results Yet

NCT05198765 | ACTIVE_NOT_RECRUITING | NA

10120 participants

Weight Loss Clinical Decision Support

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-04-19

Completion:

2025-10-31

Conditions

• Diabetes Mellitus, Type 2
• Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT05186740 | ACTIVE_NOT_RECRUITING | NA

221 participants

ProVee Urethral Expander System IDE Study (ProVIDE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-06-09

Completion:

2024-03-15

Conditions

• BPH With Symptomatic Lower Urinary Tract Symptoms

Interventions

• DEVICE
• PROCEDURE

Results Available

NCT05141682 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

11 participants

Oral Azacitidine for the Treatment of Relapsed or Refractory T-cell Large Granular Lymphocytic Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-06-29

Completion:

2026-02-19

Conditions

• T-Cell Large Granular Lymphocyte Leukemia

Interventions

• DRUG

No Results Yet

NCT05062863 | COMPLETED

139 participants

An Observational Clinical Study of the T3 Dental Implant System

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-28

Start Date:

2021-10-20

Completion:

2026-03-03

Conditions

• Edentulous Jaw

Interventions

• DEVICE

No Results Yet

NCT05050942 | ACTIVE_NOT_RECRUITING | PHASE3

332 participants

A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With GEP-NET

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2021-10-22

Completion:

2026-11-30

Conditions

• Gastro-enteropancreatic Neuroendocrine Tumor

Interventions

• DRUG

No Results Yet

NCT05044546 | ACTIVE_NOT_RECRUITING | NA

26 participants

A Behavioral Activation Prenatal and Postpartum Intervention for Depressed Pregnant Smokers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2021-10-19

Completion:

2024-11-22

Conditions

• Depression
• Tobacco Use Disorder

Interventions

• OTHER
• BEHAVIORAL
• PROCEDURE

Results Available

NCT05021835 | COMPLETED | PHASE3

6385 participants

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2021-08-30

Completion:

2026-06-09

Conditions

• Cardiovascular Risk
• Chronic Kidney Disease
• Inflammation

Interventions

• DRUG

No Results Yet