Clinical Trials Updated in 2026

NCT03784326 | ACTIVE_NOT_RECRUITING | PHASE2

43 participants

Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in Localized Esophageal and Gastroesophageal Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2019-02-19
Completion:: 2026-12-31

Conditions

Clinical Stage II Esophageal Adenocarcinoma AJCC v8
Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8
Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8
Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8
Clinical Stage III Esophageal Adenocarcinoma AJCC v8
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage IB Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IB Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage IC Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage II Esophageal Adenocarcinoma AJCC v8
Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage III Esophageal Adenocarcinoma AJCC v8
Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03744715 | TERMINATED | PHASE2

7 participants

A Study to Allow Continued Dosing and/or Follow-up of Patients Who Have Had Previous Exposure to Poziotinib

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2018-10-11
Completion:: 2023-03-03

Conditions

NSCLC
Breast Cancer

Interventions

DRUG

Results Available

NCT03612531 | ACTIVE_NOT_RECRUITING | NA

26 participants

Manual Therapy in Treating Fibrosis-Related Late Effect Dysphagia in Head and Neck Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2018-08-06
Completion:: 2022-07-15

Conditions

Cancer Survivor
Dysphagia
Fibrosis
Head and Neck Carcinoma

Interventions

PROCEDURE

Results Available

NCT03602599 | COMPLETED

190 participants

Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2018-11-15
Completion:: 2026-05-22

Conditions

Graft Versus Host Disease

No Results Yet

NCT03598608 | TERMINATED | PHASE1/PHASE2

137 participants

Study to Evaluate the Safety and Efficacy of a Combination of Favezelimab (MK-4280) and Pembrolizumab (MK-3475) in Participants With Hematologic Malignancies (MK-4280-003)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2018-10-17
Completion:: 2026-01-28

Conditions

Hodgkin Disease
Lymphoma, Non-Hodgkin
Lymphoma, B-Cell

Interventions

BIOLOGICAL

No Results Yet

NCT03581487 | COMPLETED | PHASE1/PHASE2

40 participants

Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2019-04-01
Completion:: 2025-10-30

Conditions

Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8
Stage IVA Lung Cancer AJCC v8
Stage IVB Lung Cancer AJCC v8

Interventions

BIOLOGICAL
DRUG

Results Available

NCT03556384 | COMPLETED | PHASE2

23 participants

Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2018-09-12
Completion:: 2023-06-22

Conditions

Gastrointestinal Stromal Tumors
Sdh
GIST
Cancer

Interventions

DRUG

Results Available

NCT03412045 | COMPLETED | NA

8 participants

Hyperbaric Oxygen Therapy in Sickle Cell Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2022-09-01
Completion:: 2025-06-05

Conditions

Vaso-occlusive Crisis
Sickle Cell Anemia Crisis

Interventions

DEVICE

Results Available

NCT03258658 | RECRUITING | PHASE1

10 participants

Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2027-01-31
Completion:: 2029-06-30

Conditions

Urologic Diseases
Male Urogenital Diseases
Urethral Stricture
Urethral Injury

Interventions

BIOLOGICAL

No Results Yet

NCT03180502 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2018-01-23
Completion:: 2026-07-13

Conditions

Anaplastic Astrocytoma
Anaplastic Oligoastrocytoma
Anaplastic Oligodendroglioma
Diffuse Astrocytoma
Glioma
Oligoastrocytoma
Oligodendroglioma
WHO Grade 3 Glioma

Interventions

PROCEDURE
RADIATION
OTHER
DRUG

No Results Yet

NCT03141359 | ACTIVE_NOT_RECRUITING | PHASE2

61 participants

Use of High Dose Radiation Followed by Chemotherapy and Radiation to Treat Locally Advanced NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2017-05-12
Completion:: 2023-07-12

Conditions

Lung Cancer Stage II
Lung Cancer Stage III
Non Small Cell Lung Cancer

Interventions

RADIATION
DRUG

Results Available

NCT03030066 | COMPLETED | PHASE1

47 participants

Study of DS-1001b in Patients With Gene IDH1-Mutated Gliomas

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2017-01-19
Completion:: 2021-01-31

Conditions

Glioma

Interventions

DRUG

No Results Yet

NCT03012971 | ACTIVE_NOT_RECRUITING | NA

1500 participants

Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2017-01-06
Completion:: 2026-12-11

Conditions

Elderly
Surgery
Analgesia
Dexmedetomidine
Long-term Outcome

Interventions

DRUG

No Results Yet

NCT02912572 | ACTIVE_NOT_RECRUITING | PHASE2

106 participants

Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer and of Avelumab/Talazoparib and Avelumab/Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2016-11-14
Completion:: 2023-11-15

Conditions

Metastatic Endometrial Cancer

Interventions

DRUG

Results Available

NCT02877394 | ACTIVE_NOT_RECRUITING | PHASE2

107 participants

Use of a Squatting Assist Device in Patients With Constipation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2016-09-01
Completion:: 2025-06-30

Conditions

Constipation

Interventions

DEVICE

Results Available

NCT02506933 | ACTIVE_NOT_RECRUITING | PHASE2

102 participants

Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2015-12-21
Completion:: 2018-01-25

Conditions

Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Acute Lymphoblastic Leukemia in Remission
Acute Myeloid Leukemia in Remission
Chronic Lymphocytic Leukemia
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Cytomegaloviral Infection
Hodgkin Lymphoma
Lymphadenopathy
Lymphoblastic Lymphoma
Myelodysplastic Syndrome
Myelofibrosis
Myeloproliferative Neoplasm
Non-Hodgkin Lymphoma

Interventions

OTHER
BIOLOGICAL

Results Available

NCT02363335 | COMPLETED | PHASE1

29 participants

The Role of Phosphodiesterase Inhibitors in Incretin Secretion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2015-02-13
Completion:: 2016-09-19

Conditions

Healthy Volunteers

Interventions

OTHER

No Results Yet

NCT02208362 | ACTIVE_NOT_RECRUITING | PHASE1

65 participants

Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2015-05-18
Completion:: 2021-02-08

Conditions

Recurrent Glioblastoma
Recurrent Malignant Glioma
Recurrent WHO Grade II Glioma
Recurrent WHO Grade III Glioma
Refractory Glioblastoma
Refractory Malignant Glioma
Refractory WHO Grade II Glioma
Refractory WHO Grade III Glioma

Interventions

BIOLOGICAL
OTHER
PROCEDURE

Results Available

NCT02193425 | COMPLETED | EARLY_PHASE1

112 participants

Reliability of the Human Brain Connectome

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2015-06-08
Completion:: 2023-05-23

Conditions

Normal Physiology

Interventions

DRUG
DEVICE

No Results Yet

NCT02190266 | RECRUITING

400 participants

Pathogenesis and Genetics of Disseminated or Refractory Coccidioidomycosis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2014-09-02
Completion:: 2029-07-31

Conditions

Coccidioidomycosis

No Results Yet

NCT02108496 | COMPLETED | NA

337 participants

Verifying the Effectiveness of the NUsurface® System

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2014-07-31
Completion:: 2021-06-30

Conditions

Meniscectomy
Osteoarthritis

Interventions

DEVICE
DRUG

Results Available

NCT01833650 | COMPLETED | NA

120 participants

The Use of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2018-02-01
Completion:: 2024-08-01

Conditions

Thyroid Cancer

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT01581554 | COMPLETED

15 participants

Withdrawal of Therapy After Long-Term Antiviral Treatment for Chronic Hepatitis B

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2011-05-18

Conditions

Chronic Hepatitis B e Antigen Positive
Chronic Hepatitis B e Antigen Negative

No Results Yet

NCT01574274 | ACTIVE_NOT_RECRUITING | PHASE2

240 participants

SC-PEG Asparaginase vs. Oncaspar in Pediatric Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2012-06-30
Completion:: 2021-07-31

Conditions

Acute Lymphoblastic Leukemia
Lymphoblastic Lymphoma

Interventions

DRUG

Results Available

NCT01500447 | RECRUITING

850 participants

Inherited Reproductive Disorders

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2012-04-25

Conditions

Genetic Disorder
Infertility
Hypogonadism
Amenorrhea

No Results Yet

NCT01264055 | COMPLETED

275 participants

Cross-sectional Characterization of Idiopathic Bronchiectasis

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2011-04-26

Conditions

Infection
Bronchial Diseases
Respiratory Tract Diseases

No Results Yet

NCT00756769 | RECRUITING

750 participants

Systemic Lupus Erythematosus in Gullah Health

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2003-04-30
Completion:: 2027-06-30

Conditions

Systemic Lupus Erythematosus

No Results Yet

NCT00728962 | COMPLETED

75 participants

A Study of Osseotite Certain Prevail Implants Used to Support Short Fixed Bridges With Immediate Occlusal Loading.

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2005-03-31
Completion:: 2006-05-31

Conditions

Partial Edentulism
Tooth Disease

Results Available

NCT00728754 | COMPLETED | NA

61 participants

A Study of Certain Prevail Implants Used for the Preservation of Crestal Bone in Short Fixed Bridge Cases.

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2005-03-31
Completion:: 2007-07-31

Conditions

Partial Edentulism
Tooth Disease

Interventions

DEVICE

Results Available

NCT00726063 | COMPLETED | NA

241 participants

A Prospective Study Evaluating the Performance of Nanotite Osseotite Implants When Placed by Graduate Student Programs

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2008-04-30
Completion:: 2012-10-31

Conditions

Tooth Disease
Partial Edentulism

Interventions

DEVICE

Results Available

NCT00725049 | COMPLETED | NA

37 participants

An Evaluation of Integration Success and Maintenance of Short Implants in Maxillas Needing Sinus Augmentation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2009-02-28
Completion:: 2013-07-31

Conditions

Tooth Disease
Partial Edentulism

Interventions

DEVICE

Results Available

NCT00723944 | COMPLETED | NA

102 participants

A Study of the Performance of Certain Prevail Implants Used in Short Fixed Cases

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-28
Start Date:: 2005-02-28
Completion:: 2007-04-30

Conditions

Partial Edentulism
Tooth Disease

Interventions

DEVICE

Results Available

NCT00032513 | RECRUITING

300 participants

Genetic Studies of Chronic Active Epstein-Barr Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-28
Start Date:: 2002-04-16

Conditions

Chronic Active Epstein-Barr Virus

No Results Yet

NCT07729735 | ENROLLING_BY_INVITATION | NA

40 participants

Physiotherapy After Breast Reduction Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-27
Start Date:: 2026-07-23
Completion:: 2026-08-10

Conditions

Breast
Posture
Mammaplasty
Sleep Quality

Interventions

OTHER

No Results Yet

NCT07729722 | ENROLLING_BY_INVITATION | NA

40 participants

Comparison of Chiropractic and Physiotherapy in Chronic Neck Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-27
Start Date:: 2026-07-25
Completion:: 2026-08-25

Conditions

Neck Pain
Disabilities
Chiropractic
Physiotherapy

Interventions

OTHER

No Results Yet

NCT07729709 | COMPLETED | PHASE3

100 participants

Pulsed Electromagnetic Field on Chronic Anal Fissure Healing

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-27
Start Date:: 2026-01-03
Completion:: 2026-05-22

Conditions

Anal Fissure Chronic

Interventions

DEVICE
DRUG

No Results Yet

NCT07729696 | NOT_YET_RECRUITING | NA

38 participants

Digital Psychoeducational Intervention for Young Adults With Fertility Related Distress Following Cancer Diagnosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-27
Start Date:: 2026-08-24
Completion:: 2026-12-07

Conditions

Neoplasm
Cancer
Psychoeducational Intervention
Young Adults
Fertility Outcomes
Psychological Distress
Anxiety

Interventions

BEHAVIORAL

No Results Yet

NCT07729683 | RECRUITING | NA

30 participants

Evaluation of the Effect of a Daily Dose of Wakame Seaweed on Reducing Circulating Concentrations of Advanced Glycation End Products in Patients With Stage III Chronic Kidney Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-27
Start Date:: 2026-01-27
Completion:: 2027-10-31

Conditions

Chronic Kidney Disease

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07729670 | NOT_YET_RECRUITING | PHASE2

42 participants

Multimodal Ablation Combined With Perioperative Tislelizumab and Chemotherapy for Resectable II-IIIB NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-27
Start Date:: 2026-06-30
Completion:: 2029-06-30

Conditions

NSCLC

Interventions

DEVICE
DRUG
PROCEDURE

No Results Yet

NCT07729631 | COMPLETED | NA

16 participants

Establishing the Glycaemic Index of Vegetable Smoothies

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-27
Start Date:: 2025-10-22
Completion:: 2025-12-15

Conditions

Glycaemic Index
Glycaemic Response
Glycaemic Response Measurements

Interventions

OTHER

No Results Yet