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The Use of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid Cancer

NCT01833650 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2026-07-28

No results posted yet for this study

Summary

The purpose of this study is to determine whether the use of honey mouthwashes in the prevention of salivary side effects of 131I (radioiodine) therapy.

Conditions

Interventions

DIETARY_SUPPLEMENT

thymus honey mouthwash

Based on the intervention, each patient will be instructed to suck 1 or 2 lemon candies every 2-3 h in the daytime plus 4 thymus honey mouthwashes in between (at least one hour after the candy sucking) starting 12 hours after the ingestion of 131I therapy and for a duration of no more than 4 days.

Sponsors & Collaborators

  • Cyprus University of Technology

    lead OTHER

  • Bank of Cyprus Oncology Centre

    collaborator OTHER

Principal Investigators

  • Andreas Charalambous, PhD · Cyprus University of Technology

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
FACTORIAL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-01
Primary Completion
2024-08-01
Completion
2024-08-01

Countries

  • Cyprus

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01833650 on ClinicalTrials.gov