Clinical Trials

NCT04160390 | ACTIVE_NOT_RECRUITING

72 participants

Blood Samples to Identify Biomarkers in Patients Treated With Cyclophosphamide After Donor Stem Cell Transplant

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-28

Start Date:

2018-11-13

Completion:

2027-04-24

Conditions

• Allogeneic Hematopoietic Stem Cell Transplant Recipient
• Donor
• Malignant Neoplasm

Interventions

• OTHER

No Results Yet

NCT04140162 | ACTIVE_NOT_RECRUITING | PHASE2

57 participants

Phase 2 Study With Minimal Residual Disease (MRD) Driven Adaptive Strategy in Treatment for Newly Diagnosed Multiple Myeloma (MM) With Upfront Daratumumab-based Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2020-10-05

Completion:

2024-05-02

Conditions

• Multiple Myeloma

Interventions

• DRUG

Results Available

NCT04098471 | RECRUITING | NA

168 participants

Total Meso-rectal Excision Versus Transanal Local Excision Followed by Radiotherapy for T2N0M0 Distal Rectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2021-10-01

Completion:

2027-06-01

Conditions

• Rectal Cancer

Interventions

• PROCEDURE

No Results Yet

NCT04093570 | ENROLLING_BY_INVITATION | PHASE2

332 participants

A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2019-09-30

Completion:

2027-12-31

Conditions

• Acute Myeloid Leukemia
• Chronic Myelomonocytic Leukemia
• Myelodysplastic Syndromes

Interventions

• DRUG

No Results Yet

NCT04069273 | ACTIVE_NOT_RECRUITING | PHASE2

58 participants

Novel SEQUEnced Immunotherapy With Anti-angiogenesis and Chemotherapy in Advanced gastroesophageaL Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2020-12-01

Completion:

2026-08-11

Conditions

• Gastric Cancer
• GastroEsophageal Cancer
• Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT04058756 | ACTIVE_NOT_RECRUITING | PHASE1

120 participants

Rollover Study for Continued Safety and Tolerability in Subjects Treated With Spartalizumab Alone or in Combination With Other Study Treatments

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2019-10-30

Completion:

2030-04-30

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04055428 | RECRUITING | PHASE2

200 participants

NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2020-08-15

Completion:

2026-12-31

Conditions

• Diabetes Mellitus
• Cardiovascular Diseases
• Insulin Sensitivity/Resistance
• Metabolic Disease
• Natriuretic Peptides
• Metabolism
• Energy Expenditure

Interventions

• DRUG
• OTHER
• DIETARY_SUPPLEMENT

No Results Yet

NCT04040205 | RECRUITING | PHASE2

44 participants

Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2019-10-07

Completion:

2027-06-01

Conditions

• Chondrosarcoma
• Osteosarcoma
• Soft Tissue Sarcoma

Interventions

• DRUG

No Results Yet

NCT03963375 | COMPLETED | PHASE4

47 participants

Cladribine Tablets: Collaborative Study to Evaluate Impact On Central Nervous System Biomarkers in Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2019-10-28

Completion:

2025-05-27

Conditions

• Multiple Sclerosis
• Multiple Sclerosis, Relapsing-Remitting

Interventions

• DRUG

Results Available

NCT03945305 | RECRUITING | NA

500 participants

Safety and Efficacy of Remote Ischemic Conditioning Treatment for Community-based Essential Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2023-11-25

Completion:

2026-07-31

Conditions

• Essential Hypertension

Interventions

• DEVICE
• OTHER

No Results Yet

NCT03899883 | COMPLETED | PHASE2

11 participants

Uric Acid Lowering Trial in Youth Onset T2D

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2020-01-01

Completion:

2023-04-13

Conditions

• Diabetic Kidney Disease
• Hyperuricemia
• Diabetes
• Diabetes Mellitus, Type 2
• Type2 Diabetes
• Type 2 Diabetes Mellitus
• Diabetic Nephropathies
• Diabetes Complications

Interventions

• DRUG

Results Available

NCT03893500 | COMPLETED | NA

63 participants

Utility of At-home Monitoring of Exercise Capacity by App-based 6-minute Walk Test

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2020-07-01

Completion:

2024-06-01

Conditions

• Pulmonary Arterial Hypertension

Interventions

• DEVICE

Results Available

NCT03872778 | COMPLETED | PHASE1/PHASE2

35 participants

[177Lu]-NeoB in Patients With Advanced Solid Tumors and With [68Ga]-neoB Lesion Uptake

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2019-07-24

Completion:

2025-01-07

Conditions

• Neoplasms

Interventions

• DRUG

No Results Yet

NCT03814304 | COMPLETED | NA

99 participants

tDCS in Elderly Fallers Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2019-07-08

Completion:

2025-01-24

Conditions

• Accidental Falls
• Aging

Interventions

• OTHER

Results Available

NCT03784326 | ACTIVE_NOT_RECRUITING | PHASE2

43 participants

Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in Localized Esophageal and Gastroesophageal Adenocarcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2019-02-19

Completion:

2026-12-31

Conditions

• Clinical Stage II Esophageal Adenocarcinoma AJCC v8
• Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Clinical Stage III Esophageal Adenocarcinoma AJCC v8
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IB Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IC Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage II Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage III Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8
• Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT03744715 | TERMINATED | PHASE2

7 participants

A Study to Allow Continued Dosing and/or Follow-up of Patients Who Have Had Previous Exposure to Poziotinib

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2018-10-11

Completion:

2023-03-03

Conditions

• NSCLC
• Breast Cancer

Interventions

• DRUG

Results Available

NCT03612531 | ACTIVE_NOT_RECRUITING | NA

26 participants

Manual Therapy in Treating Fibrosis-Related Late Effect Dysphagia in Head and Neck Cancer Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2018-08-06

Completion:

2022-07-15

Conditions

• Cancer Survivor
• Dysphagia
• Fibrosis
• Head and Neck Carcinoma

Interventions

• PROCEDURE

Results Available

NCT03602599 | COMPLETED

190 participants

Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-28

Start Date:

2018-11-15

Completion:

2026-05-22

Conditions

• Graft Versus Host Disease

No Results Yet

NCT03598608 | TERMINATED | PHASE1/PHASE2

137 participants

Study to Evaluate the Safety and Efficacy of a Combination of Favezelimab (MK-4280) and Pembrolizumab (MK-3475) in Participants With Hematologic Malignancies (MK-4280-003)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2018-10-17

Completion:

2026-01-28

Conditions

• Hodgkin Disease
• Lymphoma, Non-Hodgkin
• Lymphoma, B-Cell

Interventions

• BIOLOGICAL

No Results Yet

NCT03581487 | COMPLETED | PHASE1/PHASE2

40 participants

Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2019-04-01

Completion:

2025-10-30

Conditions

• Recurrent Lung Non-Small Cell Carcinoma
• Stage IV Lung Cancer AJCC v8
• Stage IVA Lung Cancer AJCC v8
• Stage IVB Lung Cancer AJCC v8

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT03556384 | COMPLETED | PHASE2

23 participants

Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2018-09-12

Completion:

2023-06-22

Conditions

• Gastrointestinal Stromal Tumors
• Sdh
• GIST
• Cancer

Interventions

• DRUG

Results Available

NCT03412045 | COMPLETED | NA

8 participants

Hyperbaric Oxygen Therapy in Sickle Cell Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2022-09-01

Completion:

2025-06-05

Conditions

• Vaso-occlusive Crisis
• Sickle Cell Anemia Crisis

Interventions

• DEVICE

Results Available

NCT03258658 | RECRUITING | PHASE1

10 participants

Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2027-01-31

Completion:

2029-06-30

Conditions

• Urologic Diseases
• Male Urogenital Diseases
• Urethral Stricture
• Urethral Injury

Interventions

• BIOLOGICAL

No Results Yet

NCT03180502 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2018-01-23

Completion:

2026-07-13

Conditions

• Anaplastic Astrocytoma
• Anaplastic Oligoastrocytoma
• Anaplastic Oligodendroglioma
• Diffuse Astrocytoma
• Glioma
• Oligoastrocytoma
• Oligodendroglioma
• WHO Grade 3 Glioma

Interventions

• PROCEDURE
• RADIATION
• OTHER
• DRUG

No Results Yet

NCT03141359 | ACTIVE_NOT_RECRUITING | PHASE2

61 participants

Use of High Dose Radiation Followed by Chemotherapy and Radiation to Treat Locally Advanced NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2017-05-12

Completion:

2023-07-12

Conditions

• Lung Cancer Stage II
• Lung Cancer Stage III
• Non Small Cell Lung Cancer

Interventions

• RADIATION
• DRUG

Results Available

NCT03030066 | COMPLETED | PHASE1

47 participants

Study of DS-1001b in Patients With Gene IDH1-Mutated Gliomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2017-01-19

Completion:

2021-01-31

Conditions

• Glioma

Interventions

• DRUG

No Results Yet

NCT03012971 | ACTIVE_NOT_RECRUITING | NA

1500 participants

Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2017-01-06

Completion:

2026-12-11

Conditions

• Elderly
• Surgery
• Analgesia
• Dexmedetomidine
• Long-term Outcome

Interventions

• DRUG

No Results Yet

NCT02912572 | ACTIVE_NOT_RECRUITING | PHASE2

106 participants

Avelumab in Patients With MSS, MSI-H and POLE-mutated Recurrent or Persistent Endometrial Cancer and of Avelumab/Talazoparib and Avelumab/Axitinib in Patients With MSS Recurrent or Persistent Endometrial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2016-11-14

Completion:

2023-11-15

Conditions

• Metastatic Endometrial Cancer

Interventions

• DRUG

Results Available

NCT02877394 | ACTIVE_NOT_RECRUITING | PHASE2

107 participants

Use of a Squatting Assist Device in Patients With Constipation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2016-09-01

Completion:

2025-06-30

Conditions

• Constipation

Interventions

• DEVICE

Results Available

NCT02772003 | ACTIVE_NOT_RECRUITING | PHASE1

33 participants

DNA Vaccine Therapy in Treating Patients With Chronic Hepatitis C Virus Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2016-06-06

Completion:

2020-03-04

Conditions

• Chronic Hepatitis
• Hepatitis C Infection
• Hepatocellular Carcinoma

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT02506933 | ACTIVE_NOT_RECRUITING | PHASE2

102 participants

Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2015-12-21

Completion:

2018-01-25

Conditions

• Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
• Acute Lymphoblastic Leukemia in Remission
• Acute Myeloid Leukemia in Remission
• Chronic Lymphocytic Leukemia
• Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
• Cytomegaloviral Infection
• Hodgkin Lymphoma
• Lymphadenopathy
• Lymphoblastic Lymphoma
• Myelodysplastic Syndrome
• Myelofibrosis
• Myeloproliferative Neoplasm
• Non-Hodgkin Lymphoma

Interventions

• OTHER
• BIOLOGICAL

Results Available

NCT02471365 | COMPLETED

11 participants

Study of Exposure to Chemicals in Consumer Products

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-28

Start Date:

2018-08-07

Completion:

2020-08-12

Conditions

• Product Use

No Results Yet

NCT02450851 | RECRUITING

20000 participants

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-28

Start Date:

2015-09-16

Completion:

2028-12-31

Conditions

• Genetic Disease

No Results Yet

NCT02423057 | COMPLETED | PHASE1

27 participants

Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2015-05-18

Completion:

2019-03-19

Conditions

• Neoplasms
• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT02363335 | COMPLETED | PHASE1

29 participants

The Role of Phosphodiesterase Inhibitors in Incretin Secretion

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2015-02-13

Completion:

2016-09-19

Conditions

• Healthy Volunteers

Interventions

• OTHER

No Results Yet

NCT02327884 | RECRUITING

1150 participants

Characterization of Diseases With Salivary Gland Involvement

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-28

Start Date:

2015-04-03

Completion:

2032-04-01

Conditions

• Healthy Volunteer
• Sjogren's Syndrome
• Salivary Gland Disease

No Results Yet

NCT02311335 | COMPLETED

140 participants

Genes Involved in Lipid Disorders

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-28

Start Date:

2014-11-26

Completion:

2021-09-02

Conditions

• Lipid Disorders

No Results Yet

NCT02257892 | RECRUITING

500 participants

Novel Genetic Disorders of the Immune System

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-28

Start Date:

2014-10-22

Completion:

2026-08-30

Conditions

• PI3KCD
• CTLA4
• STAT3GOF
• MAGT1

No Results Yet

NCT02208362 | ACTIVE_NOT_RECRUITING | PHASE1

65 participants

Genetically Modified T-cells in Treating Patients With Recurrent or Refractory Malignant Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2015-05-18

Completion:

2021-02-08

Conditions

• Recurrent Glioblastoma
• Recurrent Malignant Glioma
• Recurrent WHO Grade II Glioma
• Recurrent WHO Grade III Glioma
• Refractory Glioblastoma
• Refractory Malignant Glioma
• Refractory WHO Grade II Glioma
• Refractory WHO Grade III Glioma

Interventions

• BIOLOGICAL
• OTHER
• PROCEDURE

Results Available

NCT02193425 | COMPLETED | EARLY_PHASE1

112 participants

Reliability of the Human Brain Connectome

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-28

Start Date:

2015-06-08

Completion:

2023-05-23

Conditions

• Normal Physiology

Interventions

• DRUG
• DEVICE

No Results Yet