Clinical Trials

NCT04612751 | ACTIVE_NOT_RECRUITING | PHASE1

155 participants

Phase 1b Study of Dato-DXd in Combination With Immunotherapy With or Without Carboplatin in Advanced or Metastatic Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2021-02-02

Completion:

2026-05-04

Conditions

• Advanced or Metastatic NSCLC

Interventions

• DRUG

No Results Yet

NCT04577326 | ACTIVE_NOT_RECRUITING | PHASE1

14 participants

Mesothelin-targeted CAR T-cell Therapy in Patients With Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2020-09-30

Completion:

2026-09-30

Conditions

• Malignant Pleural Mesothelioma (MPM)

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04532697 | COMPLETED | NA

56 participants

Use of Gou-Teng to Treat Patients With Mild Cognitive Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2020-11-24

Completion:

2023-10-25

Conditions

• Mild Cognitive Impairment
• White Matter Hyperintensity

Interventions

• OTHER

No Results Yet

NCT04523922 | COMPLETED | PHASE2

175 participants

Oxytocin to Enhance Integrated Treatment for AUD and PTSD

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2021-03-29

Completion:

2026-04-13

Conditions

• PTSD
• Alcohol Use Disorder

Interventions

• DRUG
• BEHAVIORAL

No Results Yet

NCT04492670 | COMPLETED | NA

70 participants

Tui-na and Oral Chinese Medicine on KOA

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2020-09-14

Completion:

2021-10-31

Conditions

• Knee Osteoarthritis

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT04477785 | RECRUITING

4500 participants

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-27

Start Date:

2020-07-01

Completion:

2033-12-31

Conditions

• Parkinson Disease

No Results Yet

NCT04364672 | WITHDRAWN | PHASE1

0 participants

Molecular Neuroimaging to Assess the Link Between Neuroinflammation and Cognitive Impairment in Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2025-06-01

Completion:

2026-07-01

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04317794 | ACTIVE_NOT_RECRUITING

74 participants

Observational, Postmarketing Surveillance Study of Spinraza Injection (Nusinersen Sodium)

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-27

Start Date:

2019-07-02

Completion:

2027-02-05

Conditions

• Muscular Atrophy, Spinal

Interventions

• DRUG

No Results Yet

NCT04276805 | COMPLETED | NA

45 participants

Non-invasive Nerve Stimulation and Cognitive Training to Improve Cognitive Performance in Healthy Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2020-11-17

Completion:

2024-09-27

Conditions

• Aging

Interventions

• DEVICE
• BEHAVIORAL

Results Available

NCT04243616 | ACTIVE_NOT_RECRUITING | PHASE2

36 participants

Cemiplimab in High-risk or Locally Advanced Luminal and Triple Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2020-03-05

Completion:

2025-08-11

Conditions

• Invasive Breast Cancer

Interventions

• DRUG

Results Available

NCT04117087 | ACTIVE_NOT_RECRUITING | PHASE1

27 participants

Pooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected Mismatch Repair Protein (MMR-p) Colorectal and Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2020-05-28

Completion:

2027-06-01

Conditions

• Colorectal Cancer
• Pancreatic Cancer

Interventions

• DRUG

No Results Yet

NCT04045470 | RECRUITING | NA

20 participants

A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2019-12-11

Completion:

2027-07-31

Conditions

• Cutaneous T Cell Lymphoma
• Peripheral T Cell Lymphoma

Interventions

• DEVICE
• OTHER

No Results Yet

NCT04041713 | NOT_YET_RECRUITING | PHASE2

35 participants

A Pilot Study of an Antioxidant Cocktail vs. Placebo in the Treatment of Children and Adolescents With Rett Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2026-08-17

Completion:

2027-12-30

Conditions

• Rett Syndrome

Interventions

• DRUG
• OTHER

No Results Yet

NCT04012944 | ACTIVE_NOT_RECRUITING | NA

81 participants

SIRONA 2 Trial Heart Failure NYHA Class III

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2019-06-26

Completion:

2021-10-30

Conditions

• Heart Failure NYHA Class III

Interventions

• DEVICE

No Results Yet

NCT03945045 | COMPLETED | NA

201 participants

A Study of the IJV or the SCV Approach for Ultrasound-guided Implantation of TIVAD

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2019-05-21

Completion:

2024-01-25

Conditions

• Venous Thrombosis
• Catheter-Related Infections
• Catheter Mechanical Failure Rate

Interventions

• PROCEDURE

No Results Yet

NCT03927820 | COMPLETED | NA

914 participants

A Pharmacist-Led Intervention to Increase Inhaler Access and Reduce Hospital Readmissions (PILLAR)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2019-09-09

Completion:

2026-06-01

Conditions

• COPD
• Asthma

Interventions

• OTHER

No Results Yet

NCT03629197 | COMPLETED | NA

95 participants

Improving Communication About Pain and Opioids

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2018-08-15

Completion:

2019-11-05

Conditions

• Pain, Chronic
• Communication Research
• Opioid Use

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT03626285 | AVAILABLE

Bone Marrow Transplantation Using CD34-Selected Stem Cells From Related or Unrelated Donors in Treating Participants With Cancer or Other Disorders

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-07-27

Conditions

• Benign Neoplasm
• Bone Marrow Transplantation Recipient
• Hematopoietic Cell Transplantation Recipient
• Malignant Neoplasm

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT03582176 | COMPLETED | PHASE3

395 participants

PrEvention of Posttraumatic Joint contractuRes With Ketotifen 2

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2019-04-26

Completion:

2024-09-29

Conditions

• Elbow Fracture
• Elbow Injury
• Elbow Dislocation

Interventions

• DRUG

No Results Yet

NCT03539393 | AVAILABLE

Fremanezumab Managed Access Program for Pediatric Patients

Study Type:

EXPANDED_ACCESS

Last Updated:

2026-07-27

Conditions

• Migraine

Interventions

• DRUG

No Results Yet

NCT03471117 | TERMINATED | PHASE4

5 participants

Pioglitazone to Reduce Sympathetic Overactivity in CKD Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2018-04-01

Completion:

2020-01-14

Conditions

• Chronic Kidney Diseases

Interventions

• DRUG
• OTHER

Results Available

NCT03417739 | TERMINATED | PHASE2

13 participants

A Phase II Study of BVD-523 in Metastatic Uveal Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2018-03-26

Completion:

2020-05-05

Conditions

• Uveal Melanoma

Interventions

• DRUG

Results Available

NCT03298451 | ACTIVE_NOT_RECRUITING | PHASE3

1324 participants

Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2017-10-11

Completion:

2021-08-27

Conditions

• Hepatocellular Carcinoma

Interventions

• DRUG

Results Available

NCT03203525 | TERMINATED | PHASE1

38 participants

Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2020-06-23

Completion:

2026-07-22

Conditions

• Advanced Malignant Neoplasm
• Colorectal Carcinoma Metastatic in the Liver
• Metastatic Malignant Neoplasm in the Liver
• Refractory Malignant Neoplasm

Interventions

• BIOLOGICAL
• DRUG
• PROCEDURE

No Results Yet

NCT03178123 | TERMINATED | PHASE2

6 participants

The Study of JS001 Compared to High-Dose Interferon In Patients With Mucosal Melanoma That Has Been Removed by Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2017-05-31

Completion:

2019-06-30

Conditions

• Mucosal Melanoma

Interventions

• BIOLOGICAL

No Results Yet

NCT03075917 | COMPLETED | NA

137 participants

Validation of an Allergic Rhinitis Control Test in Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2017-05-04

Completion:

2026-07-18

Conditions

• Allergic Rhinitis

Interventions

• OTHER

No Results Yet

NCT03025308 | COMPLETED | PHASE3

2731 participants

Long Term Extension Study to Assess the Safety and Efficacy of Filgotinib in Adults With Rheumatoid Arthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2017-02-28

Completion:

2025-05-16

Conditions

• Rheumatoid Arthritis

Interventions

• DRUG

Results Available

NCT02675959 | RECRUITING | PHASE2

40 participants

Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2017-07-01

Completion:

2026-12-31

Conditions

• Sickle Cell Disease

Interventions

• DRUG

No Results Yet

NCT02595424 | ACTIVE_NOT_RECRUITING | PHASE2

67 participants

Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced Poorly Differentiated (G3) Non-Small Cell Gastrointestinal Neuroendocrine Carcinomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2015-11-06

Completion:

2025-04-23

Conditions

• Gastric Neuroendocrine Carcinoma
• Intestinal Neuroendocrine Carcinoma
• Pancreatic Neuroendocrine Carcinoma

Interventions

• DRUG
• OTHER

Results Available

NCT02505386 | COMPLETED | PHASE4

27 participants

Pharmacokinetics of Ertapenem in Patients Aged Over 75

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2014-08-31

Completion:

2016-08-31

Conditions

• Infections

Interventions

• DRUG

No Results Yet

NCT02476786 | RECRUITING | PHASE2

50 participants

Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence Score

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2017-01-17

Completion:

2027-01-31

Conditions

• Breast Cancer
• Cancer of Breast
• Breast Neoplasms
• Cancer of the Breast

Interventions

• BEHAVIORAL
• DRUG
• OTHER

No Results Yet

NCT02445391 | ACTIVE_NOT_RECRUITING | PHASE3

415 participants

Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2015-10-20

Completion:

2021-04-07

Conditions

• Estrogen Receptor Negative
• HER2/Neu Negative
• Invasive Breast Carcinoma
• Progesterone Receptor Negative
• Stage II Breast Cancer
• Stage IIA Breast Cancer
• Stage IIB Breast Cancer
• Stage III Breast Cancer
• Stage IIIA Breast Cancer
• Stage IIIB Breast Cancer
• Stage IIIC Breast Cancer
• Triple-Negative Breast Carcinoma

Interventions

• DRUG

Results Available

NCT02328963 | COMPLETED | PHASE4

186 participants

Proportion of CMV Seropositive Kidney Transplant Recipients Who Will Develop a CMV Infection When Treated With an Immunosuppressive Regimen Including Everolimus and Reduced Dose of Cyclosporine Versus an Immunosuppressive Regimen With Mycophenolic Acid and Standard Dose of Cyclosporine A

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2014-05-02

Completion:

2018-10-10

Conditions

• Transplantation Infection
• Cytomegalovirus Infection

Interventions

• DRUG

No Results Yet

NCT02286089 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

24 participants

Safety and Efficacy Study of OpRegen for Treatment of Advanced Dry-Form Age-Related Macular Degeneration

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2015-04-01

Completion:

2021-12-31

Conditions

• Age-Related Macular Degeneration

Interventions

• BIOLOGICAL

Results Available

NCT01876771 | SUSPENDED | PHASE2

413 participants

A Trial to Assess the Safety and Effectiveness of Lutetium-177 Octreotate Therapy in Neuroendocrine Tumours

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2014-04-29

Completion:

2042-12-31

Conditions

• Carcinoma, Neuroendocrine

Interventions

• DRUG

No Results Yet

NCT01843374 | ACTIVE_NOT_RECRUITING | PHASE2

571 participants

Randomized, Double-blind Study Comparing Tremelimumab to Placebo in Subjects With Unresectable Malignant Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2013-05-17

Completion:

2016-01-24

Conditions

• Unresectable Pleural or Peritoneal Malignant Mesothelioma

Interventions

• DRUG

Results Available

NCT01816152 | COMPLETED | NA

44 participants

Methodology Issues in a Tailored Light Treatment for Persons With Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2020-01-01

Completion:

2024-05-10

Conditions

• Sleep Disturbances
• Depression

Interventions

• OTHER

Results Available

NCT01764529 | COMPLETED

789 participants

Modifiers of Disease Severity in Cerebral Cavernous Malformations

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-27

Start Date:

2010-04-27

Completion:

2025-03-31

Conditions

• Cavernous Angioma, Familial
• Cerebral Cavernous Malformations
• Cerebral Cavernous Hemangioma

No Results Yet

NCT01760005 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

490 participants

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2012-12-31

Completion:

2028-04-30

Conditions

• Alzheimers Disease
• Dementia
• Alzheimers Disease, Familial

Interventions

• DRUG

No Results Yet

NCT01339052 | COMPLETED | PHASE2

65 participants

Phase II Study of BKM120 for Subjects With Recurrent Glioblastoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-27

Start Date:

2011-09-30

Completion:

2016-10-31

Conditions

• Glioblastoma

Interventions

• DRUG
• PROCEDURE

Results Available