Observational, Postmarketing Surveillance Study of Spinraza Injection (Nusinersen Sodium)

Study of the Functional Effects of Nusinersen in 5q-spinal Muscular Amyotrophy Adults (SMA Type 2 or 3 Forms)

NCT04576494 ·Status: COMPLETED ·Phase: NA

A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies

NCT02594124 ·Status: COMPLETED ·Phase: PHASE3

Monitoring to the Evolution of Motor Function in SMA Type II Adults Patients Treated With SPINRAZA®

NCT04159987 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA

A Study to Assess the Safety and Tolerability of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA).

NCT02462759 ·Status: TERMINATED ·Phase: PHASE2

Non-Interventional, Postmarketing Surveillance Study of Nusinersen Sodium Injection

NCT04419233 ·Status: COMPLETED

Pulmonary Function Test Changes and Respiratory Muscle Strength Trends in Spinal Muscular Atrophy Patients Receiving Nusinersen Treatments

NCT04050852 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1

Effect of Nusinersen on Adults With Spinal Muscular Atrophy

NCT03878030 ·Status: COMPLETED

A Study to Learn How Nusinersen (Spinraza) Affects Participants With Spinal Muscular Atrophy (SMA) Who Took it Before or During Pregnancy And About The Health of Their Babies

NCT05789758 ·Status: RECRUITING

An Open-label Safety, Tolerability, and Dose-range Finding Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA)

NCT01494701 ·Status: COMPLETED ·Phase: PHASE1

Ultrasound-assisted or Landmark-based Intrathecal Administration of Nusinersen in Adult Patients With Spinal Muscular Atrophy (The EchoSpin Study)

NCT05644899 ·Status: COMPLETED

A Study of Multiple Doses of Nusinersen (ISIS 396443) Delivered to Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy

NCT02386553 ·Status: COMPLETED ·Phase: PHASE2

Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy

NCT04089566 ·Status: COMPLETED ·Phase: PHASE3

Metabolomics of Children With SMA

NCT04587492 ·Status: COMPLETED

An Open-label Safety, Tolerability and Dose-Range Finding Study of Multiple Doses of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy

NCT01703988 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

A Study to Learn About the Effect of Nusinersen (BIIB058) Given as Injections to Children With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Onasemnogene Abeparvovec (RESPOND)

NCT04488133 ·Status: COMPLETED ·Phase: PHASE4

A Study to Learn About the Long-Term Safety of Higher Doses of Nusinersen (BIIB058) Given as Injections to Participants With Spinal Muscular Atrophy (SMA) Who Took Part in an Earlier Nusinersen Trial (ONWARD)

NCT04729907 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3

Responsiveness and Validation Study of MFM-32 in SMA Patients Treated With Nusinersen

NCT04602195 ·Status: COMPLETED

A Clinical Study Evaluating the Safety and Efficacy of SKG0201 Injection in Patients With Spinal Muscular Atrophy Type 1

NCT06191354 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA

Adults With SMA Treated With Nusinersen

NCT04591678 ·Status: COMPLETED

Ultrasound-assisted vs Landmark Based Intrathecal Administration of Nusinersen

NCT04674618 ·Status: COMPLETED ·Phase: NA

Effect of Goserelin (Zoladex®) in Spinal and Bulbar Muscular Atrophy

NCT00851461 ·Status: COMPLETED ·Phase: PHASE4

Characterization of the Clinical-epidemiological Profile of Patients With SMA5q Types II and III: Observational Study

NCT04404764 ·Status: COMPLETED

A Trial of Hydroxyurea in Spinal Muscular Atrophy

NCT00485511 ·Status: COMPLETED ·Phase: PHASE2/PHASE3

A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy

NCT05337553 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3

An Observational Study Comparing Delandistrogene Moxeparvovec (ELEVIDYS) With Standard of Care in Participants With Duchenne Muscular Dystrophy

NCT06270719 ·Status: ENROLLING_BY_INVITATION