Clinical Trials

NCT04881630 | COMPLETED | NA

532 participants

Mobile Contingency Management for Smoking Cessation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2022-11-08

Completion:

2025-09-21

Conditions

• Smoking Cessation

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04874311 | ACTIVE_NOT_RECRUITING | PHASE2

80 participants

Bintrafusp Alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2022-03-01

Completion:

2027-01-31

Conditions

• Advanced Soft-tissue Sarcoma
• Metastatic Soft-tissue Sarcoma

Interventions

• DRUG

No Results Yet

NCT04867616 | COMPLETED | PHASE2

466 participants

A Study to Test the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Patients With Mild Cognitive Impairment or Mild Alzheimer's Disease (AD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-06-09

Completion:

2024-05-24

Conditions

• Alzheimer's Disease

Interventions

• OTHER
• BIOLOGICAL

No Results Yet

NCT04836936 | ACTIVE_NOT_RECRUITING | NA

60 participants

Auriculotherapy in the Treatment of Pre-Operative Anxiety

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-04-13

Completion:

2026-04-28

Conditions

• Anxiety Preoperative

Interventions

• DEVICE

No Results Yet

NCT04833465 | RECRUITING

90 participants

Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-24

Start Date:

2021-07-16

Completion:

2028-04-30

Conditions

• Juvenile Idiopathic Arthritis
• Systemic Lupus Erythematosus
• Fibromyalgia

Interventions

• OTHER

No Results Yet

NCT04827979 | COMPLETED | PHASE1/PHASE2

19 participants

Daratumumab and Belatacept for Desensitization

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-11-01

Completion:

2026-04-02

Conditions

• Highly Sensitized Prospective Kidney Transplant Recipients

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT04786977 | RECRUITING

40 participants

Physiologic Measure of VIPN

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-24

Start Date:

2021-09-20

Completion:

2027-05-31

Conditions

• Chemotherapy-induced Peripheral Neuropathy

Interventions

• OTHER

No Results Yet

NCT04785937 | COMPLETED | NA

28 participants

Accuracy of Imaging Techniques in Diagnosing Steatohepatitis and Fibrosis in NAFLD Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-01-01

Completion:

2022-06-01

Conditions

• Non-Alcoholic Fatty Liver Disease
• Steatohepatitis, Nonalcoholic
• Liver Fibroses

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04776655 | ACTIVE_NOT_RECRUITING | PHASE3

280 participants

Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-04-30

Completion:

2025-05-04

Conditions

• Colorectal Cancer
• Metastatic Colorectal Cancer
• RAS Mutation

Interventions

• DRUG

No Results Yet

NCT04754321 | RECRUITING | PHASE1

45 participants

Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2022-05-12

Completion:

2026-12-31

Conditions

• Head and Neck Carcinoma of Unknown Primary
• Locally Recurrent Head and Neck Squamous Cell Carcinoma
• Recurrent Laryngeal Squamous Cell Carcinoma
• Recurrent Oral Cavity Squamous Cell Carcinoma
• Recurrent Pharyngeal Squamous Cell Carcinoma
• Resectable Head and Neck Squamous Cell Carcinoma

Interventions

• RADIATION
• BIOLOGICAL
• OTHER
• PROCEDURE

No Results Yet

NCT04704986 | COMPLETED | PHASE4

202 participants

Comparison of PolarX and the Arctic Front Cryoballoons for PVI in Patients With Symptomatic Paroxysmal AF

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-03-29

Completion:

2023-07-31

Conditions

• Paroxysmal Atrial Fibrillation

Interventions

• DEVICE
• DRUG

Results Available

NCT04686097 | RECRUITING | NA

84 participants

Percutaneous Electrocoagulation Versus Sclerosing Foam for Patients With Incompetent Perforating Veins

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-01-01

Completion:

2027-12-31

Conditions

• Incompetent Perforating Veins

Interventions

• PROCEDURE

No Results Yet

NCT04685577 | COMPLETED | PHASE2

50 participants

Safety, Tolerability and Efficacy of Nefopam Cream in Burn Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2022-07-10

Completion:

2026-02-17

Conditions

• Burn; Multiple Body Regions, Max. Second Degree
• Third-Degree Burn
• Burn Degree Second

Interventions

• DRUG
• OTHER

No Results Yet

NCT04677413 | ACTIVE_NOT_RECRUITING | PHASE1

27 participants

Ultra-fractionated Radiotherapy for Rectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-06-03

Completion:

2027-06-30

Conditions

• Rectal Cancer

Interventions

• RADIATION

No Results Yet

NCT04653896 | COMPLETED | NA

32 participants

A Powered Exoskeleton for Veterans With Knee OA

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-06-01

Completion:

2025-11-13

Conditions

• Knee Osteoarthritis

Interventions

• DEVICE

No Results Yet

NCT04634877 | ACTIVE_NOT_RECRUITING | PHASE3

990 participants

Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-01-10

Completion:

2026-09-15

Conditions

• Endometrial Neoplasms

Interventions

• BIOLOGICAL
• DRUG
• RADIATION

No Results Yet

NCT04618913 | COMPLETED

1 participants

Anticoagulation in Patients With Venous Thromboembolism and Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-24

Start Date:

2020-12-14

Completion:

2026-06-22

Conditions

• Neoplasms
• Embolism

Interventions

• DRUG

No Results Yet

NCT04615013 | RECRUITING | PHASE1

24 participants

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-11-23

Completion:

2027-10-31

Conditions

• Cervical Esophagus Adenocarcinoma
• Clinical Stage II Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8
• Clinical Stage III Esophageal Adenocarcinoma AJCC v8
• Gastroesophageal Junction Adenocarcinoma
• Pathologic Stage II Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage III Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8
• Thoracic Esophagus Adenocarcinoma

Interventions

• DRUG
• OTHER
• RADIATION

No Results Yet

NCT04570423 | RECRUITING | PHASE2

40 participants

A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-05-20

Completion:

2027-10-31

Conditions

• Solid Tumors
• Lymphoma

Interventions

• DRUG

No Results Yet

NCT04557748 | COMPLETED

1030 participants

LURN: Urinary Urgency Phenotyping Protocol

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-24

Start Date:

2021-02-17

Completion:

2025-08-12

Conditions

• Lower Urinary Tract Symptoms

Interventions

• OTHER

No Results Yet

NCT04548999 | ACTIVE_NOT_RECRUITING | PHASE3

769 participants

A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-12-03

Completion:

2025-06-30

Conditions

• Multiple Sclerosis

Interventions

• DRUG

Results Available

NCT04530110 | COMPLETED | PHASE3

499 participants

A Trial to Test if Fremanezumab is Effective in Preventing Migraine in Children and Adolescents

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-09-16

Completion:

2025-08-15

Conditions

• Migraine

Interventions

• DRUG

Results Available

NCT04528082 | RECRUITING | PHASE3

60 participants

Apremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-09-09

Completion:

2030-02-07

Conditions

• Behçet Disease

Interventions

• DRUG

No Results Yet

NCT04526119 | COMPLETED | PHASE3

55 participants

A Phase III Trial of Z-338 in Paediatric Patients With Functional Dyspepsia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-02-22

Completion:

2026-03-02

Conditions

• Functional Dyspepsia

Interventions

• DRUG

No Results Yet

NCT04498260 | COMPLETED | PHASE4

30 participants

Intralesional Steroid Injection Versus Oral Prednisolone in Prevention of Esophageal Stricture

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-01-21

Completion:

2022-05-31

Conditions

• Esophageal Stenosis

Interventions

• DRUG

No Results Yet

NCT04488523 | COMPLETED | NA

93 participants

Family Telehealth Project for Foster Care Youth

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-07-01

Completion:

2025-11-01

Conditions

• Parent-Child Relations
• Communication

Interventions

• BEHAVIORAL

No Results Yet

NCT04481919 | ACTIVE_NOT_RECRUITING | PHASE2

474 participants

Randomized Controlled Trial of urinE chemiStry Guided aCute heArt faiLure treATmEnt (ESCALATE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2022-05-01

Completion:

2025-11-22

Conditions

• Heart Failure
• Acute Heart Failure

Interventions

• DRUG

No Results Yet

NCT04461808 | ACTIVE_NOT_RECRUITING | NA

10156 participants

Tomosynthesis as Primary Test for Breast Cancer Screening

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-03-01

Completion:

2027-04-30

Conditions

• Breast Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04372381 | WITHDRAWN | NA

0 participants

Supra-Annular vs. Annular ValvEs for Small Annuli

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-05-12

Completion:

2025-04-30

Conditions

• Aortic Valve Stenosis
• Implantation, Heart Valve Prosthesis

Interventions

• DEVICE

No Results Yet

NCT04350138 | COMPLETED | PHASE2

2606 participants

Safety and Efficacy Study of Meningococcal Group B Vaccine rMenB+OMV NZ (Bexsero) to Prevent Gonococcal Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-12-29

Completion:

2026-02-18

Conditions

• Gonococcal Infection

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04349059 | RECRUITING | NA

46 participants

The Impact of Dietary Pattern on Erectile Function

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2023-10-30

Completion:

2026-12-31

Conditions

• Erectile Dysfunction

Interventions

• OTHER

No Results Yet

NCT04333524 | ACTIVE_NOT_RECRUITING

496 participants

FDG PET Evaluation for Marginal Zone Lymphoma and Its Prognostic Role

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-24

Start Date:

2020-12-01

Completion:

2026-10-15

Conditions

• Marginal Zone Lymphoma

No Results Yet

NCT04322383 | RECRUITING | PHASE2

40 participants

Binimetinib for People With Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and Variant

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-01-07

Completion:

2028-04-30

Conditions

• Hairy Cell Leukemia

Interventions

• DRUG

No Results Yet

NCT04304014 | COMPLETED | NA

120 participants

Assessment of the Impact of Type of Probiotic, Delivery Type and Feeding Type on Baby's Microbiota After Dysbiotic Delivery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-03-05

Completion:

2024-03-12

Conditions

• Dysbiosis

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04258137 | ACTIVE_NOT_RECRUITING | NA

332 participants

Circulating DNA to Improve Outcome of Oncology PatiEnt. A Randomized Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-09-04

Completion:

2027-05-24

Conditions

• Colorectal Cancer
• Non Small Cell Lung Cancer

Interventions

• GENETIC

No Results Yet

NCT04235803 | COMPLETED | NA

78 participants

Telemedicine Follow-up for Routine, Low-Risk Oculoplastic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-09-01

Completion:

2021-07-27

Conditions

• Eyelid Diseases
• Ptosis, Eyelid
• Blepharoptosis
• Dermatochalasis
• Ectropion
• Entropion
• Eyelid Tumor
• Skin Cancer, Eyelid
• Floppy Eyelid Syndrome

Interventions

• OTHER

No Results Yet

NCT04208490 | COMPLETED | NA

357 participants

Implementation and Effectiveness Trial of HN-STAR

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-02-23

Completion:

2026-05-12

Conditions

• Head and Neck Cancer

Interventions

• OTHER

No Results Yet

NCT04203277 | COMPLETED | NA

8 participants

Improving Vaccinations for Young Children (IVY)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-04-01

Completion:

2020-02-28

Conditions

• Vaccination Refusal

Interventions

• OTHER

No Results Yet

NCT04203173 | COMPLETED | NA

450 participants

Financial Incentives And Nurse Coaching to Enhance Diabetes Outcomes (FINANCE-DM)-1

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-12-01

Completion:

2025-06-30

Conditions

• Type 2 Diabetes

Interventions

• BEHAVIORAL

Results Available

NCT04123197 | COMPLETED | NA

306 participants

Mental Stress and Myocardial Ischemia After MI: Sex Differences, Mechanisms and Prognosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-02-28

Completion:

2025-05-31

Conditions

• Myocardial Infarction

Interventions

• OTHER

Results Available