Clinical Trials

NCT04322383 | RECRUITING | PHASE2

40 participants

Binimetinib for People With Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and Variant

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-01-07

Completion:

2028-04-30

Conditions

• Hairy Cell Leukemia

Interventions

• DRUG

No Results Yet

NCT04304014 | COMPLETED | NA

120 participants

Assessment of the Impact of Type of Probiotic, Delivery Type and Feeding Type on Baby's Microbiota After Dysbiotic Delivery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-03-05

Completion:

2024-03-12

Conditions

• Dysbiosis

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04258137 | ACTIVE_NOT_RECRUITING | NA

332 participants

Circulating DNA to Improve Outcome of Oncology PatiEnt. A Randomized Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-09-04

Completion:

2027-05-24

Conditions

• Colorectal Cancer
• Non Small Cell Lung Cancer

Interventions

• GENETIC

No Results Yet

NCT04235803 | COMPLETED | NA

78 participants

Telemedicine Follow-up for Routine, Low-Risk Oculoplastic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-09-01

Completion:

2021-07-27

Conditions

• Eyelid Diseases
• Ptosis, Eyelid
• Blepharoptosis
• Dermatochalasis
• Ectropion
• Entropion
• Eyelid Tumor
• Skin Cancer, Eyelid
• Floppy Eyelid Syndrome

Interventions

• OTHER

No Results Yet

NCT04208490 | COMPLETED | NA

357 participants

Implementation and Effectiveness Trial of HN-STAR

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-02-23

Completion:

2026-05-12

Conditions

• Head and Neck Cancer

Interventions

• OTHER

No Results Yet

NCT04203277 | COMPLETED | NA

8 participants

Improving Vaccinations for Young Children (IVY)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-04-01

Completion:

2020-02-28

Conditions

• Vaccination Refusal

Interventions

• OTHER

No Results Yet

NCT04203173 | COMPLETED | NA

450 participants

Financial Incentives And Nurse Coaching to Enhance Diabetes Outcomes (FINANCE-DM)-1

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-12-01

Completion:

2025-06-30

Conditions

• Type 2 Diabetes

Interventions

• BEHAVIORAL

Results Available

NCT04123197 | COMPLETED | NA

306 participants

Mental Stress and Myocardial Ischemia After MI: Sex Differences, Mechanisms and Prognosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-02-28

Completion:

2025-05-31

Conditions

• Myocardial Infarction

Interventions

• OTHER

Results Available

NCT04112186 | COMPLETED | NA

157 participants

Mindfulness-Oriented Recovery Enhancement (MORE) in Heroin Addiction

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-06-21

Completion:

2024-09-11

Conditions

• Opiate Use Disorder

Interventions

• BEHAVIORAL

No Results Yet

NCT04089059 | ACTIVE_NOT_RECRUITING | NA

738 participants

PROACTIVE-HF IDE Trial Heart Failure NYHA Class III

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-01-10

Completion:

2028-04-30

Conditions

• Heart Failure NYHA Class III

Interventions

• DEVICE

Results Available

NCT04076059 | ACTIVE_NOT_RECRUITING | PHASE3

180 participants

An Efficacy and Safety Study of Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus ADT in Chinese Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-09-11

Completion:

2022-11-18

Conditions

• Metastatic Hormone Sensitive Prostate Cancer

Interventions

• DRUG

Results Available

NCT04053322 | ACTIVE_NOT_RECRUITING | PHASE2

172 participants

Durvalumab, With Olaparib and Fulvestrant in Advanced ER+, HER2- Breast Cancer Patients.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-08-26

Completion:

2023-11-15

Conditions

• ER-positive and HER2-negative Metastatic or Locally Advanced Breast Cancer
• a Germline or Somatic BRCA Mutation, or a Deleterious Alteration of Other Genes Involved in Homologous Recombination Repair (HRR) or in MSI Status

Interventions

• DRUG

No Results Yet

NCT03957252 | ACTIVE_NOT_RECRUITING

2800 participants

Validation of ClarityDX Prostate as a Reflex Test to Refine the Prediction of Clinically-significant Prostate Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-24

Start Date:

2019-06-06

Completion:

2027-03-31

Conditions

• Prostate Cancer
• Prostate Cancer Screening
• Performance Assessment of Novel Test

No Results Yet

NCT03922555 | RECRUITING | PHASE1

18 participants

ASTX727 in Recurrent/Progressive Non-enhancing IDH Mutant Gliomas

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-07-12

Completion:

2027-01-01

Conditions

• Neurological Cancer

Interventions

• DRUG

No Results Yet

NCT03915678 | ACTIVE_NOT_RECRUITING | PHASE2

247 participants

Atezolizumab Combined With BDB001 AnD Immunogenic Radiotherapy in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2021-03-31

Completion:

2026-12-31

Conditions

• Solid Tumor, Adult
• Pancreatic Cancer
• Virus-associated Tumors
• Non Small Cell Lung Cancer
• Melanoma
• Bladder Cancer
• Triple Negative Breast Cancer

Interventions

• DRUG

No Results Yet

NCT03907475 | RECRUITING | PHASE2

115 participants

Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-07-16

Completion:

2027-06-01

Conditions

• Locally Advanced Malignant Solid Neoplasm
• Metastatic Malignant Solid Neoplasm

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT03853616 | ACTIVE_NOT_RECRUITING | PHASE1

48 participants

MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2018-11-26

Completion:

2026-09-30

Conditions

• Acute Lymphoblastic Leukemia Recurrent
• B-cell Lymphoma Recurrent
• B-cell Lymphoma Refractory
• Chronic Lymphocytic Leukemia Recurrent
• Chronic Lymphocytic Leukemia Refractory

Interventions

• BIOLOGICAL

No Results Yet

NCT03778307 | COMPLETED

168 participants

Key Dimensions of PTSD and ED

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-24

Start Date:

2019-11-20

Completion:

2025-06-30

Conditions

• Trauma
• PTSD
• Endothelial Dysfunction

Interventions

• BEHAVIORAL

Results Available

NCT03768063 | ACTIVE_NOT_RECRUITING | PHASE3

1000 participants

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-02-28

Completion:

2028-07-05

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT03730181 | COMPLETED | PHASE1/PHASE2

69 participants

Tuberculosis Clinical Trials Consortium Study 35

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-11-12

Completion:

2024-12-15

Conditions

• Latent Tuberculosis

Interventions

• DRUG

Results Available

NCT03729453 | ACTIVE_NOT_RECRUITING

100 participants

Intra-operative Pancreatoscopy in Patients With IPMN

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-24

Start Date:

2019-03-20

Completion:

2022-08-11

Conditions

• Intraductal Papillary Mucinous Neoplasm

Interventions

• DEVICE

No Results Yet

NCT03693014 | ACTIVE_NOT_RECRUITING | PHASE2

69 participants

A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2018-10-01

Completion:

2027-10-31

Conditions

• Metastatic Cancer
• Melanoma Cancer
• Lung Cancer
• Bladder Cancer
• Renal Cancer
• Head/Neck Cancers

Interventions

• RADIATION
• BIOLOGICAL

No Results Yet

NCT03672539 | COMPLETED | PHASE2

50 participants

Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2018-11-07

Completion:

2026-07-17

Conditions

• Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
• Chronic Myelomonocytic Leukemia
• High Risk Myelodysplastic Syndrome
• Myelodysplastic Syndrome
• Recurrent Acute Myeloid Leukemia
• Refractory Acute Myeloid Leukemia

Interventions

• DRUG
• OTHER

No Results Yet

NCT03665337 | COMPLETED | NA

59 participants

The Reducing Risk Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2020-09-01

Completion:

2024-10-24

Conditions

• Insomnia
• Delayed Sleep Phase

Interventions

• BEHAVIORAL

No Results Yet

NCT03531736 | ACTIVE_NOT_RECRUITING | PHASE1

17 participants

T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intensity Regimen in Patients With Hematologic Malignancies and Aplastic Anemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2018-05-09

Completion:

2027-05-31

Conditions

• Myeloid Diseases

Interventions

• DRUG
• RADIATION
• PROCEDURE

No Results Yet

NCT03529799 | TERMINATED | NA

40 participants

Disparity Driven Vergence in Mild Traumatic Brain Injury (mTBI)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2018-04-20

Completion:

2019-09-25

Conditions

• Mild Traumatic Brain Injury

Interventions

• DEVICE

Results Available

NCT03478514 | ACTIVE_NOT_RECRUITING | PHASE2

39 participants

Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2018-09-11

Completion:

2025-12-19

Conditions

• Mantle Cell Lymphoma
• B Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT03456843 | ACTIVE_NOT_RECRUITING | PHASE2

190 participants

Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2018-03-20

Completion:

2027-03-31

Conditions

• Stage IV Prostate Adenocarcinoma AJCC v7

Interventions

• DRUG
• OTHER
• PROCEDURE

No Results Yet

NCT03384134 | COMPLETED | NA

407 participants

Treating Pain in Children With Cancer: Pain Buddy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2019-08-01

Completion:

2024-10-14

Conditions

• Cancer

Interventions

• OTHER

Results Available

NCT03284710 | COMPLETED | PHASE1/PHASE2

132 participants

Safety and Immunogenicity of Clade C ALVAC and gp120 HIV Vaccine

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2017-06-19

Completion:

2019-12-12

Conditions

• HIV Infections

Interventions

• BIOLOGICAL

Results Available

NCT03235414 | COMPLETED | NA

101 participants

Normal Liver Stiffness by MR Elastography

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2018-02-19

Completion:

2020-06-25

Conditions

• Liver Diseases

Interventions

• DEVICE
• DIAGNOSTIC_TEST

Results Available

NCT03223753 | COMPLETED | PHASE3

299 participants

Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2017-11-29

Completion:

2025-03-31

Conditions

• Carcinoma In Situ
• Hematopoietic and Lymphatic System Neoplasm
• Malignant Solid Neoplasm

Interventions

• OTHER
• DEVICE

Results Available

NCT03219359 | RECRUITING | PHASE2

50 participants

Autologous Stem Cell Transplant for Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2018-02-22

Completion:

2028-10-31

Conditions

• Crohn Disease

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT03181100 | ACTIVE_NOT_RECRUITING | PHASE2

50 participants

Atezolizumab With Chemotherapy in Treating Patients With Anaplastic or Poorly Differentiated Thyroid Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2017-07-27

Completion:

2027-07-31

Conditions

• Metastatic Thyroid Gland Carcinoma
• Poorly Differentiated Thyroid Gland Carcinoma
• Stage IVA Thyroid Gland Anaplastic Carcinoma AJCC v8
• Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v8
• Stage IVC Thyroid Gland Anaplastic Carcinoma AJCC v8
• Thyroid Gland Anaplastic Carcinoma
• Unresectable Thyroid Gland Carcinoma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT03161678 | COMPLETED | PHASE4

111 participants

CES1 Crossover Trial of Clopidogrel and Ticagrelor

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2017-08-22

Completion:

2022-12-12

Conditions

• Myocardial Infarction
• Thrombosis
• Platelet Dysfunction

Interventions

• DRUG

Results Available

NCT03155620 | ACTIVE_NOT_RECRUITING | PHASE2

1377 participants

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2017-07-31

Completion:

2025-03-31

Conditions

• Advanced Malignant Solid Neoplasm
• Ann Arbor Stage III Non-Hodgkin Lymphoma
• Ann Arbor Stage IV Non-Hodgkin Lymphoma
• Histiocytic Sarcoma
• Juvenile Xanthogranuloma
• Langerhans Cell Histiocytosis
• Malignant Glioma
• Recurrent Childhood Rhabdomyosarcoma
• Recurrent Ependymoma
• Recurrent Ewing Sarcoma
• Recurrent Glioma
• Recurrent Hepatoblastoma
• Recurrent Langerhans Cell Histiocytosis
• Recurrent Malignant Germ Cell Tumor
• Recurrent Malignant Solid Neoplasm
• Recurrent Medulloblastoma
• Recurrent Neuroblastoma
• Recurrent Non-Hodgkin Lymphoma
• Recurrent Osteosarcoma
• Recurrent Peripheral Primitive Neuroectodermal Tumor
• Recurrent Primary Central Nervous System Neoplasm
• Recurrent Rhabdoid Tumor
• Recurrent Soft Tissue Sarcoma
• Refractory Ewing Sarcoma
• Refractory Glioma
• Refractory Hepatoblastoma
• Refractory Langerhans Cell Histiocytosis
• Refractory Malignant Germ Cell Tumor
• Refractory Malignant Solid Neoplasm
• Refractory Medulloblastoma
• Refractory Neuroblastoma
• Refractory Non-Hodgkin Lymphoma
• Refractory Osteosarcoma
• Refractory Peripheral Primitive Neuroectodermal Tumor
• Refractory Primary Central Nervous System Neoplasm
• Refractory Rhabdoid Tumor
• Refractory Rhabdomyosarcoma
• Rhabdoid Tumor
• Stage III Osteosarcoma AJCC v7
• Stage III Soft Tissue Sarcoma AJCC v7
• Stage IV Osteosarcoma AJCC v7
• Stage IV Soft Tissue Sarcoma AJCC v7
• Stage IVA Osteosarcoma AJCC v7
• Stage IVB Osteosarcoma AJCC v7
• Wilms Tumor

Interventions

• PROCEDURE
• DRUG
• OTHER

Results Available

NCT03109444 | COMPLETED

75 participants

Normative Radiographic Parameters and Growth Curve of Hips Less Than Six Weeks of Gestational Age Using Ultrasound

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-24

Start Date:

2017-10-25

Completion:

2024-10-01

Conditions

• Newborn
• Hip Dysplasia

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03106363 | COMPLETED | NA

49 participants

Combined Alcohol and Cannabis Effects on Skills of Young Drivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2017-07-04

Completion:

2020-01-17

Conditions

• Psychomotor Impairment

Interventions

• DRUG

Results Available

NCT03090646 | TERMINATED | NA

140 participants

Use of Financial Incentives to Increase Live Kidney Donor Follow-up Compliance

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2017-03-22

Completion:

2024-12-03

Conditions

• Living Donors
• Nephrectomy
• Kidney

Interventions

• OTHER

No Results Yet

NCT03045159 | COMPLETED | NA

115 participants

Strong Families Strong Forces: Supporting Active Duty Families With Very Young Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-24

Start Date:

2016-03-31

Completion:

2019-03-31

Conditions

• Deployment

Interventions

• BEHAVIORAL

No Results Yet