Key Dimensions of PTSD and ED
NCT03778307 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 168
Last updated 2026-05-07
Summary
This study will test whether endothelial dysfunction could be the early subclinical mechanism by which posttraumatic stress disorder (PTSD) increases cardiovascular disease (CVD) risk, and whether posttraumatic fear-a key component of PTSD-or another PTSD dimension could be the target to offset that risk. The results of this study may help trauma-exposed individuals who are at risk of having CVD events.
Conditions
Interventions
- BEHAVIORAL
-
Psychophysiological fear conditioning and extinction task
Behavioral task to assess psychophysiological measures of fear
- BEHAVIORAL
-
Eyetracking task
Behavioral task to assess dysphoria-relevant attention allocation
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH -
University of California, Los Angeles
lead OTHER
Principal Investigators
-
Jennifer A Sumner, PhD · University of California, Los Angeles
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-11-20
- Primary Completion
- 2025-06-30
- Completion
- 2025-06-30
Countries
- United States
Study Locations
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