Key Dimensions of PTSD and ED

NCT03778307 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 168

Last updated 2026-05-07

No results posted yet for this study

Summary

This study will test whether endothelial dysfunction could be the early subclinical mechanism by which posttraumatic stress disorder (PTSD) increases cardiovascular disease (CVD) risk, and whether posttraumatic fear-a key component of PTSD-or another PTSD dimension could be the target to offset that risk. The results of this study may help trauma-exposed individuals who are at risk of having CVD events.

Conditions

Interventions

BEHAVIORAL

Psychophysiological fear conditioning and extinction task

Behavioral task to assess psychophysiological measures of fear

BEHAVIORAL

Eyetracking task

Behavioral task to assess dysphoria-relevant attention allocation

Sponsors & Collaborators

Principal Investigators

  • Jennifer A Sumner, PhD · University of California, Los Angeles

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-20
Primary Completion
2025-06-30
Completion
2025-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03778307 on ClinicalTrials.gov