Clinical Trials

NCT04515875 | COMPLETED | NA

420 participants

PRIMA Intervention for Adults With Mild Cognitive Impairment and Their Caregivers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2021-12-13
Completion:: 2025-07-20

Conditions

Mild Cognitive Impairment

Interventions

BEHAVIORAL

Results Available

NCT04493281 | COMPLETED | PHASE1

42 participants

Bioequivalence Study of Oral Suspension and Intravenous Formulation of Edaravone in Healthy Adult Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2019-03-22
Completion:: 2019-04-21

Conditions

Healthy Adult Subjects

Interventions

DRUG

Results Available

NCT04481789 | COMPLETED | PHASE1

84 participants

Clinical Pharmacology Study of Oral Edaravone in Healthy Adult Males (Drug Interaction Study and Preliminary Regimen-Finding Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2018-10-17
Completion:: 2018-12-20

Conditions

Healthy Adult Subjects

Interventions

DRUG

Results Available

NCT04441554 | RECRUITING

600 participants

7 Tesla MRI Evaluation of the Spine

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-15
Start Date:: 2020-03-04
Completion:: 2027-09-30

Conditions

Magnetic Resonance Imaging
Cervical Spine Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04407247 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

47 participants

Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2020-07-09
Completion:: 2027-12-31

Conditions

Colitis
Lung Non-Small Cell Carcinoma
Malignant Genitourinary System Neoplasm
Malignant Solid Neoplasm
Melanoma

Interventions

BIOLOGICAL

No Results Yet

NCT04404465 | ENROLLING_BY_INVITATION

3000 participants

Health eHeart BEAT-AFib - Health eHeart Biomarkers of Early Atrial Transformation in Atrial Fibrillation

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-15
Start Date:: 2020-09-15
Completion:: 2030-09-15

Conditions

Atrial Fibrillation

No Results Yet

NCT04374877 | COMPLETED | PHASE1

145 participants

Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2020-04-22
Completion:: 2025-05-28

Conditions

Advanced Solid Tumor
Clear Cell Renal Cell Carcinoma
Hepatocellular Carcinoma
Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT04367506 | COMPLETED | NA

59 participants

Pilot Testing a Digital Intervention to Improve Smoking Cessation in Persons With Serious Mental Illness

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2022-09-06
Completion:: 2024-03-25

Conditions

Tobacco Cessation

Interventions

BEHAVIORAL

Results Available

NCT04287049 | COMPLETED | PHASE2

10 participants

A Study of Standard Drugs for Mycobacterium Avium Complex

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2020-02-24
Completion:: 2025-03-21

Conditions

Mycobacterium Avium Complex

Interventions

DRUG

Results Available

NCT04284774 | ACTIVE_NOT_RECRUITING | PHASE2

5 participants

Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2020-10-13
Completion:: 2024-03-31

Conditions

Malignant Solid Neoplasm
Recurrent Adrenal Gland Pheochromocytoma
Recurrent Ectomesenchymoma
Recurrent Ependymoma
Recurrent Ewing Sarcoma
Recurrent Hepatoblastoma
Recurrent Kidney Wilms Tumor
Recurrent Langerhans Cell Histiocytosis
Recurrent Malignant Germ Cell Tumor
Recurrent Malignant Glioma
Recurrent Medulloblastoma
Recurrent Melanoma
Recurrent Neuroblastoma
Recurrent Non-Hodgkin Lymphoma
Recurrent Osteosarcoma
Recurrent Peripheral Primitive Neuroectodermal Tumor
Recurrent Rhabdoid Tumor
Recurrent Rhabdoid Tumor of the Kidney
Recurrent Rhabdomyosarcoma
Recurrent Soft Tissue Sarcoma
Recurrent Thyroid Gland Carcinoma
Recurrent WHO Grade 2 Glioma
Refractory Adrenal Gland Pheochromocytoma
Refractory Ependymoma
Refractory Ewing Sarcoma
Refractory Hepatoblastoma
Refractory Langerhans Cell Histiocytosis
Refractory Malignant Germ Cell Tumor
Refractory Malignant Glioma
Refractory Medulloblastoma
Refractory Melanoma
Refractory Neuroblastoma
Refractory Non-Hodgkin Lymphoma
Refractory Osteosarcoma
Refractory Peripheral Primitive Neuroectodermal Tumor
Refractory Rhabdoid Tumor
Refractory Rhabdoid Tumor of the Kidney
Refractory Rhabdomyosarcoma
Refractory Soft Tissue Sarcoma
Refractory Thyroid Gland Carcinoma
Refractory WHO Grade 2 Glioma

Interventions

DRUG

Results Available

NCT04267887 | ACTIVE_NOT_RECRUITING | PHASE2

7 participants

Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2020-05-11
Completion:: 2028-01-01

Conditions

Castration-Sensitive Prostate Carcinoma
Metastatic Prostate Carcinoma
Stage IVB Prostate Cancer AJCC v8

Interventions

DRUG
PROCEDURE
OTHER

No Results Yet

NCT04234841 | RECRUITING

750 participants

Avr Thrombosis OutcoMe Study

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-15
Start Date:: 2020-02-01
Completion:: 2028-01-31

Conditions

Aortic Stenosis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04217551 | COMPLETED | NA

1158 participants

Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2020-05-18
Completion:: 2025-08-25

Conditions

Cardiac Arrest, Out-Of-Hospital
Hypothermia, Induced
Hypoxia-Ischemia, Brain

Interventions

DEVICE

No Results Yet

NCT04176224 | COMPLETED | PHASE1

9 participants

Clinical Pharmacology Study of Oral Edaravone in Patients With Amyotrophic Lateral Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2019-04-17
Completion:: 2019-09-04

Conditions

Japanese Patients With ALS

Interventions

DRUG

Results Available

NCT04122001 | ACTIVE_NOT_RECRUITING | NA

90 participants

Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2020-08-17
Completion:: 2026-11-30

Conditions

Alzheimer Disease, Early Onset
Atypical Alzheimer's Disease
Logopenic Progressive Aphasia

Interventions

DEVICE
OTHER

No Results Yet

NCT04096430 | RECRUITING | NA

96 participants

Evaluation of Effectiveness of Child-oriented Goal-setting in Paediatric Rehabilitation (the ENGAGE Approach)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2022-03-01
Completion:: 2026-08-31

Conditions

Autism Spectrum Disorder
Neurodevelopmental Disorders
Cerebral Palsy

Interventions

BEHAVIORAL

No Results Yet

NCT04038619 | RECRUITING | PHASE1

40 participants

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2021-02-01
Completion:: 2027-12-31

Conditions

Cervical Cancer
Colitis
Diarrhea
Malignant Genitourinary System Neoplasm
Melanoma
Lung Cancer
Ovarian Cancer
Uterine Cancer
Breast Cancer

Interventions

PROCEDURE
DRUG

No Results Yet

NCT04029090 | COMPLETED | PHASE1

27 participants

A Study to Evaluate the Effect of MCI-186 at Therapeutic and Supra-Therapeutic Doses on the QT Interval(QT)/Corrected QT Interval(QTc) Interval in Healthy Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2018-09-18
Completion:: 2018-10-20

Conditions

Healthy Adult Subjects

Interventions

DRUG

Results Available

NCT04018638 | ACTIVE_NOT_RECRUITING | NA

30 participants

Blood-Flow Restriction Exercise Following a Knee Replacement

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2019-06-25
Completion:: 2027-12-25

Conditions

Knee Injuries
Knee Osteoarthritis
Knee Arthritis

Interventions

OTHER

No Results Yet

NCT03960827 | COMPLETED | NA

1836 participants

Molecular Transducers of Physical Activity Consortium

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2019-08-28
Completion:: 2025-05-31

Conditions

Physical Activity

Interventions

OTHER

Results Available

NCT03952962 | RECRUITING | NA

12 participants

Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2022-10-28
Completion:: 2027-07-31

Conditions

Treatment Resistant Depression
Undergoing Deep Brain Stimulation (DBS) Surgery

Interventions

DEVICE

No Results Yet

NCT03913169 | COMPLETED | NA

1806 participants

Interprofessional Practice Education for Health Professional Students

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2015-08-19
Completion:: 2020-12-30

Conditions

Interprofessional Relations

Interventions

OTHER

No Results Yet

NCT03896568 | RECRUITING | PHASE1

36 participants

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2019-02-12
Completion:: 2027-09-30

Conditions

IDH1 wt Allele
Recurrent Anaplastic Astrocytoma
Recurrent Glioblastoma
Recurrent Gliosarcoma
Recurrent Malignant Glioma

Interventions

BIOLOGICAL
PROCEDURE

No Results Yet

NCT03891446 | COMPLETED | PHASE3

455 participants

Long-term Safety and Efficacy Extension Trial of Bimatoprost SR

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2019-03-27
Completion:: 2026-06-19

Conditions

Open-Angle Glaucoma
Ocular Hypertension

Interventions

DRUG
OTHER

No Results Yet

NCT03843528 | ACTIVE_NOT_RECRUITING | PHASE1

15 participants

Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2019-05-01
Completion:: 2027-07-30

Conditions

Acute Myeloid Leukemia
Myelodysplastic Syndromes
Mixed Phenotype Acute Leukemia
Juvenile Myelomonocytic Leukemia

Interventions

DRUG

No Results Yet

NCT03824210 | COMPLETED

50 participants

A Study to Co-produce a Young Carers App

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-15
Start Date:: 2019-03-20
Completion:: 2020-12-01

Conditions

Caring

Interventions

OTHER

No Results Yet

NCT03819296 | RECRUITING | PHASE1

800 participants

Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2021-02-21
Completion:: 2026-10-31

Conditions

Clinical Stage 0 Cutaneous Melanoma AJCC v8
Clinical Stage I Cutaneous Melanoma AJCC v8
Clinical Stage IA Cutaneous Melanoma AJCC v8
Clinical Stage IB Cutaneous Melanoma AJCC v8
Clinical Stage II Cutaneous Melanoma AJCC v8
Clinical Stage IIA Cutaneous Melanoma AJCC v8
Clinical Stage IIB Cutaneous Melanoma AJCC v8
Clinical Stage IIC Cutaneous Melanoma AJCC v8
Clinical Stage III Cutaneous Melanoma AJCC v8
Clinical Stage IV Cutaneous Melanoma AJCC v8
Colitis
Lung Non-Small Cell Carcinoma
Malignant Genitourinary System Neoplasm
Malignant Solid Neoplasm
Pathologic Stage 0 Cutaneous Melanoma AJCC v8
Pathologic Stage I Cutaneous Melanoma AJCC v8
Pathologic Stage IA Cutaneous Melanoma AJCC v8
Pathologic Stage IB Cutaneous Melanoma AJCC v8
Pathologic Stage II Cutaneous Melanoma AJCC v8
Pathologic Stage IIA Cutaneous Melanoma AJCC v8
Pathologic Stage IIB Cutaneous Melanoma AJCC v8
Pathologic Stage IIC Cutaneous Melanoma AJCC v8
Pathologic Stage III Cutaneous Melanoma AJCC v8
Pathologic Stage IIIA Cutaneous Melanoma AJCC v8
Pathologic Stage IIIB Cutaneous Melanoma AJCC v8
Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
Pathologic Stage IIID Cutaneous Melanoma AJCC v8
Pathologic Stage IV Cutaneous Melanoma AJCC v8
Stage 0 Lung Cancer AJCC v8
Stage I Lung Cancer AJCC v8
Stage IA1 Lung Cancer AJCC v8
Stage IA2 Lung Cancer AJCC v8
Stage IA3 Lung Cancer AJCC v8
Stage IB Lung Cancer AJCC v8
Stage II Lung Cancer AJCC v8
Stage IIA Lung Cancer AJCC v8
Stage IIB Lung Cancer AJCC v8
Stage III Lung Cancer AJCC v8
Stage IIIA Lung Cancer AJCC v8
Stage IIIB Lung Cancer AJCC v8
Stage IIIC Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
Stage IVA Lung Cancer AJCC v8
Stage IVB Lung Cancer AJCC v8

Interventions

OTHER
PROCEDURE
BIOLOGICAL
DRUG

No Results Yet

NCT03778957 | ACTIVE_NOT_RECRUITING | PHASE3

724 participants

A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2018-11-30
Completion:: 2023-09-11

Conditions

Hepatocellular Carcinoma

Interventions

DRUG
OTHER
PROCEDURE

No Results Yet

NCT03682081 | COMPLETED | NA

76 participants

Interventions for Patients With Alzheimer's Disease and Dysphagia

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2020-09-25
Completion:: 2025-08-30

Conditions

Dementia
Dysphagia
Alzheimer Disease

Interventions

DEVICE

No Results Yet

NCT03664544 | COMPLETED | PHASE1

12 participants

PK Study in Subjects With Severe Hepatic Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2018-11-06
Completion:: 2019-03-25

Conditions

Severe Hepatic Impairment
Healthy

Interventions

DRUG

Results Available

NCT03655782 | ACTIVE_NOT_RECRUITING | NA

90 participants

Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2023-07-01
Completion:: 2029-07-30

Conditions

MTBI - Mild Traumatic Brain Injury

Interventions

BEHAVIORAL

No Results Yet

NCT03456076 | ACTIVE_NOT_RECRUITING | PHASE3

257 participants

A Study Comparing Adjuvant Alectinib Versus Adjuvant Platinum-Based Chemotherapy in Patients With ALK Positive Non-Small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2018-08-16
Completion:: 2023-06-26

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG

Results Available

NCT03418181 | COMPLETED | NA

44 participants

Does Incremental Initiation of Haemodialysis Preserve Native Kidney Function?

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2018-01-08
Completion:: 2020-05-02

Conditions

Kidney Failure
Dialysis

Interventions

PROCEDURE

No Results Yet

NCT03384836 | SUSPENDED | PHASE1/PHASE2

47 participants

Propranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2018-01-31
Completion:: 2027-05-31

Conditions

Stage IIIC Cutaneous Melanoma AJCC v7
Stage IV Cutaneous Melanoma AJCC v6 and v7

Interventions

OTHER
BIOLOGICAL
DRUG

No Results Yet

NCT03317158 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

186 participants

Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2017-11-21
Completion:: 2028-12-31

Conditions

Urothelial Carcinoma
Bladder Cancer

Interventions

DRUG
RADIATION
BIOLOGICAL
OTHER

No Results Yet

NCT03289234 | COMPLETED | PHASE1

22 participants

Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Hepatic Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2016-11-16
Completion:: 2018-07-20

Conditions

Hepatic Impairment
Healthy

Interventions

DRUG

Results Available

NCT03289208 | COMPLETED | PHASE1

30 participants

Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Renal Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2016-10-27
Completion:: 2018-04-16

Conditions

Renal Impairment
Healthy

Interventions

DRUG

Results Available

NCT03261544 | RECRUITING

50 participants

Abductor Reattachment Methods in Proximal Femur Replacements: What is the Best Method?

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-15
Start Date:: 2017-11-10
Completion:: 2027-06-30

Conditions

Sarcoma
Bone Metastases
Proximal Femur Replacement

Interventions

PROCEDURE

No Results Yet

NCT03172689 | COMPLETED | NA

11 participants

Validation of CardioQ Versus PiCCO in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2017-08-29
Completion:: 2025-07-01

Conditions

Cardiac Output

Interventions

DEVICE

No Results Yet

NCT03152773 | TERMINATED | NA

22 participants

Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive Guidewires

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-15
Start Date:: 2017-08-02
Completion:: 2021-12-14

Conditions

Pulmonary Artery Hypertension
Congenital Heart Disease
Structural Heart Disease

Interventions

DIAGNOSTIC_TEST

Results Available