Clinical Pharmacology Study of Oral Edaravone in Patients With Amyotrophic Lateral Sclerosis

A Study to Evaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS)

NCT05039099 ·Status: COMPLETED ·Phase: PHASE2

The Safety and Effectiveness of Cholinergic Receptor Block Therapy in the Treatment of ALS

NCT04391361 ·Status: UNKNOWN ·Phase: PHASE2

Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS)

NCT00072709 ·Status: COMPLETED ·Phase: PHASE2

A Long-term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS)

NCT00230074 ·Status: COMPLETED ·Phase: PHASE2

A 12-week, Multicenter, Safety and Dose-ranging Study of 3 Oral Doses of TCH346 in Patients With Amyotrophic Lateral Sclerosis

NCT00036413 ·Status: COMPLETED ·Phase: PHASE2

Clinical Study to Evaluate the Efficacy and Safety of FB1006 in the Treatment of ALS Patients

NCT05923905 ·Status: RECRUITING ·Phase: PHASE4

Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS

NCT06126315 ·Status: RECRUITING ·Phase: PHASE2/PHASE3

FHND1002 for ALS Treatment: Phase 2

NCT07138014 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2

Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211)

NCT00931944 ·Status: COMPLETED ·Phase: PHASE2

Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS

NCT04057898 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3

Placebo Controlled Study of ONO2506PO in the Presence of Riluzole in Patients With Amyotrophic Lateral Sclerosis (ALS)

NCT00403104 ·Status: COMPLETED ·Phase: PHASE2

A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis

NCT05006352 ·Status: COMPLETED ·Phase: PHASE1

A Study Evaluating the Safety and Tolerability of QRL-201 in ALS

NCT05633459 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1

A Phase II Multi-centre, Extension Study to Investigate the Long Term Safety of ONO-2506PO in Patients Diagnosed With Amyotrophic Lateral Sclerosis (ALS)

NCT00694941 ·Status: COMPLETED ·Phase: PHASE2

A Study Exploring the PK/PD Relationship of QRL-101 in Adults With ALS

NCT06714396 ·Status: COMPLETED ·Phase: PHASE1

Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS)

NCT02238626 ·Status: COMPLETED ·Phase: PHASE2

Clenbuterol on Motor Function in Individuals With Amyotrophic Lateral Sclerosis

NCT04245709 ·Status: COMPLETED ·Phase: PHASE2

A Single Ascending Dose of HRS-2162 in Healthy Subjects

NCT07195604 ·Status: RECRUITING ·Phase: PHASE1

Platform Trial to Assess the Efficacy of Multiple Drugs in Amyotrophic Lateral Sclerosis (ALS)

NCT06008249 ·Status: TERMINATED ·Phase: PHASE3

Safety, Tolerability, and Pharmacokinetics of FHND1002 Granules in Healthy Adults

NCT06782958 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE1

A Study to Evaluate the Safety and Pharmacokinetics of Ataluren in Participants From ≥6 Months to <2 Years of Age With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)

NCT04336826 ·Status: COMPLETED ·Phase: PHASE2

ALCAR Prophylaxis Study

NCT00225160 ·Status: UNKNOWN ·Phase: PHASE2

A Clinical Trial of Safety and Efficacy of Fasudil in Subjects With Amyotrophic Lateral Sclerosis (ALS)

NCT01935518 ·Status: UNKNOWN ·Phase: PHASE2

Open-label Clinical Trial of Lacosamide in ALS

NCT03186040 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

A Study to Evaluate the Efficacy, Safety, and Tolerability of E2086 Compared to Placebo and Active Comparator in Adult Participants With Narcolepsy Type 1

NCT06462404 ·Status: COMPLETED ·Phase: PHASE1