Clinical Trials

NCT06816498 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

1 participants

Personalized Antisense Oligonucleotide Therapy for A Single Participant With LMNB1 Mutation Associated Autosomal Dominant Leukodystrophy (ADLD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-17

Completion:

2027-03-31

Conditions

• Autosomal Dominant Leukodystrophy

Interventions

• DRUG

No Results Yet

NCT06805513 | COMPLETED | PHASE3

2212 participants

Actual Use Trial of Tadalafil 5 mg

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-01-30

Completion:

2026-03-02

Conditions

• Erectile Dysfunction

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT06796543 | RECRUITING | NA

70 participants

Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-25

Completion:

2028-03-31

Conditions

• Metastatic Sarcoma
• Radiation Therapy Patient
• Ewing Sarcoma
• Rhabdomyosarcoma

Interventions

• RADIATION

No Results Yet

NCT06787729 | RECRUITING | NA

50 participants

At Home Wearable Sensors and Smartphone for Stroke Survivors With Upper Limb Motor Challenges.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2026-04-20

Completion:

2027-01-31

Conditions

• Stroke

Interventions

• DEVICE

No Results Yet

NCT06785129 | RECRUITING

120 participants

Endometriosis and Migraine

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2025-02-12

Completion:

2028-01-01

Conditions

• Migraine
• Endometriosis

Interventions

• DEVICE
• BEHAVIORAL
• BIOLOGICAL

No Results Yet

NCT06784063 | COMPLETED | NA

40 participants

Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-04-10

Completion:

2025-06-13

Conditions

• Astigmatism

Interventions

• DEVICE

Results Available

NCT06762275 | RECRUITING | NA

566 participants

The Impact of a Diagnostic Strategy for Acute Appendicitis in Children With Acute Abdominal Pain in Primary Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-06

Completion:

2028-03-31

Conditions

• Appendicitis Acute
• Acute Abdomen in Children

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06754774 | COMPLETED | NA

40 participants

Shoulder Endurance Test: Normative Values in a Population of Female Handball Players Aged 14 to 18 in Intensive Training Structures.

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-12-18

Completion:

2025-05-19

Conditions

• Healthy Subjects 14 to 18 Years Old

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06750432 | ACTIVE_NOT_RECRUITING | PHASE1

144 participants

PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-12-13

Completion:

2026-12-31

Conditions

• Alzheimer Disease, Early Onset

Interventions

• DRUG

No Results Yet

NCT06740890 | RECRUITING | PHASE4

30 participants

Exercise and Olanzapine-samidorphan

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-06-26

Completion:

2027-04-30

Conditions

• Schizophenia Disorder
• Schizoaffective Disorder
• Bipolar Disorder I or II
• Bipolar Disorder NOS

Interventions

• DRUG

No Results Yet

NCT06725030 | RECRUITING

455 participants

A Post-market, Real-world Experience: Expanding Access to Care by Incorporating the Symani® Surgical System and Enabling Surgeons

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2025-09-22

Completion:

2027-09-01

Conditions

• Open Surgery
• Lymphedema
• Free Tissue Transfer
• Microsurgery
• Anastomosis, Surgical

Interventions

• DEVICE

No Results Yet

NCT06703476 | RECRUITING | PHASE3

530 participants

A Study of Surgical Techniques During Cystectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-11-21

Completion:

2028-11-30

Conditions

• Bladder Cancer

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT06700356 | RECRUITING | NA

5 participants

Thalamus Seizure Detection With a Deep Brain Stimulator System

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2026-07-01

Completion:

2026-11-30

Conditions

• Epilepsy; Seizure

Interventions

• DEVICE

No Results Yet

NCT06698822 | RECRUITING | PHASE2

20 participants

A Phase 2 Trial to Assess Safety and Efficacy of Tofacitinib 2% Cream in the Treatment of Cutaneous T-cell Lymphoma (CTCL), Stages IA, IB, and IIA

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-10

Completion:

2027-06-19

Conditions

• Cutaneous T-Cell Lymphoma

Interventions

• DRUG

No Results Yet

NCT06686901 | NOT_YET_RECRUITING | NA

60 participants

A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2027-01-30

Completion:

2029-07-01

Conditions

• Suicidal Ideation
• Suicide Attempt

Interventions

• BEHAVIORAL

No Results Yet

NCT06685068 | TERMINATED | PHASE1/PHASE2

23 participants

A Phase 1/2 Study of GEN1286 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-11-13

Completion:

2026-03-30

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT06652633 | RECRUITING | PHASE3

546 participants

Long-term Follow-up of Participants Treated With Galapagos Chimeric Antigen Receptor (CAR) T-cell Therapies

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-09-09

Completion:

2039-07-31

Conditions

• Hematological Malignancies

Interventions

• GENETIC

No Results Yet

NCT06651554 | RECRUITING | NA

228 participants

Technology-assisted Methods to Advance Suicide Prevention Among Youth in Colombia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-05-12

Completion:

2026-12-15

Conditions

• Suicidal Ideations
• Suicidal Behaviors
• Depression, Anxiety
• Well-being

Interventions

• BEHAVIORAL

No Results Yet

NCT06644625 | RECRUITING

1665 participants

CHAAMP (CHArlotte Advocate MGUS Project) Internal Pilot Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-01

Completion:

2035-01-31

Conditions

• Multiple Myeloma
• Multiple Myeloma Progression
• Monoclonal Gammopathy of Undetermined Significance (MGUS)
• Smoldering Multiple Myeloma (SMM)
• Plasma Cell Disorders

Interventions

• OTHER

No Results Yet

NCT06639386 | COMPLETED

68 participants

Vaccine Confidence Study Among Historically Marginalized Racial and Ethnic Groups

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2025-01-31

Completion:

2026-07-01

Conditions

• Vaccine Hesitancy
• Vaccine Refusal

No Results Yet

NCT06629961 | COMPLETED | NA

32 participants

Impact of Transepithelial Abutment Connection and Disconnection in Dental Implants

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-11-01

Completion:

2025-11-01

Conditions

• Bone Loss
• Bacterium; Agent
• Satisfaction, Patient

Interventions

• PROCEDURE

No Results Yet

NCT06607406 | RECRUITING | NA

75 participants

Postoperative Radiotherapy for Intermediate- and High-risk Patients With HNSCC Greater Than 6 Weeks After Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-01-21

Completion:

2030-01-31

Conditions

• Head and Neck Cancer
• Head and Neck Squamous Cell Carcinoma HNSCC

Interventions

• RADIATION

No Results Yet

NCT06605196 | NOT_YET_RECRUITING | NA

364 participants

Improving Cancer Prevention and Control Through Academic-local Public Health Department Partnerships

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2026-09-30

Completion:

2028-09-30

Conditions

• Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT06605105 | ENROLLING_BY_INVITATION | PHASE3

468 participants

Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-07-18

Completion:

2028-03-15

Conditions

• Major Depressive Disorder

Interventions

• DRUG

No Results Yet

NCT06604442 | COMPLETED | PHASE4

62 participants

Intrapatient Comparison of Urinary Radioactivity Following Piflufolastat (18F) and Flotufolastat (18F) PET in Men With Low PSA Biochemical Recurrence of Prostate Cancer Following Radical Prostatectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-12-04

Completion:

2025-08-29

Conditions

• Prostate Cancer

Interventions

• DRUG

Results Available

NCT06601777 | ACTIVE_NOT_RECRUITING | NA

196 participants

Evaluation of the Effectiveness, Safety, and Cost of a Smart Hospital System for Patients With Chronic Obstructive Pulmonary Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-09-11

Completion:

2026-08-06

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT06581731 | COMPLETED | NA

64 participants

Comparison of Remifentanil With a Combination of Remimazolam and Dexmedetomidine for Awake Tracheal Intubation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-06-14

Completion:

2026-03-04

Conditions

• Difficult or Failed Intubation
• Sedative Adverse Reaction

Interventions

• DRUG

No Results Yet

NCT06557005 | RECRUITING | NA

1320 participants

Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-05-23

Completion:

2027-05-23

Conditions

• Anxiety
• Depression
• Obesity
• Diabetes
• Postpartum
• Pregnancy
• Hypertension

Interventions

• OTHER

No Results Yet

NCT06537310 | ACTIVE_NOT_RECRUITING | PHASE1

34 participants

A Dose-escalation Study of RO7567132 as Single Agent and in Combination With Atezolizumab in Participants With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-09-16

Completion:

2027-05-12

Conditions

• Cancer-Neoplasms

Interventions

• DRUG

No Results Yet

NCT06527339 | NOT_YET_RECRUITING | NA

36 participants

Effect of Dry Needling Plus Vibration on Myofascial Trigger Points in Individuals With Nonspecific Low Back Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2026-09-30

Completion:

2027-03-31

Conditions

• Low Back Pain
• Dry Needling
• Trigger Points
• Vibration

Interventions

• OTHER

No Results Yet

NCT06526988 | RECRUITING | NA

2200 participants

Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-06

Completion:

2028-09-01

Conditions

• Heart Failure With Reduced Ejection Fraction

Interventions

• BEHAVIORAL

No Results Yet

NCT06523621 | ACTIVE_NOT_RECRUITING | PHASE2

1 participants

Nivolumab in Multiple Myeloma Patients After Idecabtagene Vicleucel

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2025-02-28

Completion:

2026-03-21

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT06522906 | COMPLETED | NA

48 participants

Mobilizing Hispanics With Knee Osteoarthritis

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-11-15

Completion:

2025-11-30

Conditions

• Osteoarthritis, Knee

Interventions

• BEHAVIORAL

No Results Yet

NCT06517719 | RECRUITING

500 participants

Real-world Experience With Lutetium Vipivotide Tetraxetan in Metastatic Castration Resistant Prostate Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2024-09-04

Completion:

2028-02-01

Conditions

• Metastatic Castration Resistant Prostate Cancer

Interventions

• OTHER

No Results Yet

NCT06506487 | COMPLETED | NA

142 participants

Exploratory Evaluation of Staff-Mediated Doll Therapy in Chinese Residential Dementia Care: A Mixed-Methods Cluster Randomized Pilot Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-07-31

Completion:

2025-12-31

Conditions

• Dementia

Interventions

• BEHAVIORAL

No Results Yet

NCT06495424 | ACTIVE_NOT_RECRUITING

144 participants

Observational Study to Evaluate the Efficacy of Sustained QUTENZA® Use in Painful Diabetic Peripheral Neuropathy

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2025-03-14

Completion:

2027-03-01

Conditions

• Peripheral Diabetic Neuropathy
• Painful Diabetic Neuropathy

Interventions

• DRUG

No Results Yet

NCT06493214 | COMPLETED | NA

46 participants

Interrupting Prolonged Sitting With ACTivity (InPACT) at Home Optimization Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-08-20

Completion:

2025-05-12

Conditions

• Adherence, Treatment
• Physical Inactivity

Interventions

• BEHAVIORAL

Results Available

NCT06490003 | RECRUITING

150 participants

Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell Carcinoma

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2004-06-01

Completion:

2028-06-18

Conditions

• Esophageal Squamous Cell Carcinoma
• Chemotherapy Effect
• DNA Methylation

Interventions

• DRUG

No Results Yet

NCT06481501 | SUSPENDED | NA

40 participants

Mindfulness Intervention for Individuals With HIV and Chronic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-13

Start Date:

2024-06-24

Completion:

2027-06-24

Conditions

• Chronic Pain
• HIV Infections

Interventions

• BEHAVIORAL

No Results Yet

NCT06480591 | RECRUITING

35 participants

Evaluation of the Pathobiology of CALR-mutated MPN Cells

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-13

Start Date:

2025-01-21

Completion:

2027-07-31

Conditions

• Myeloproliferative Neoplasm

Interventions

• OTHER

No Results Yet