Clinical Trials

NCT04815694 | RECRUITING | NA

179 participants

THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI Guided Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2021-03-17

Completion:

2027-01-31

Conditions

• Neoadjuvant Chemoradiotherapy
• Locally Advanced Rectal Cancer
• Pathological Complete Response

Interventions

• RADIATION

No Results Yet

NCT04812353 | COMPLETED | NA

208 participants

Foot and Ankle Arthrodesis or Osteotomy With Io-Fix Type Fixation

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2014-04-01

Completion:

2021-09-24

Conditions

• Foot and Ankle Arthrodesis
• Foot and Ankle Osteotomy

Interventions

• OTHER

No Results Yet

NCT04797481 | ACTIVE_NOT_RECRUITING | NA

40 participants

Pilot Testing of an Online Rehabilitation Intervention for People With Heart Failure (PORIAS-HF).

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2023-06-01

Completion:

2026-10-28

Conditions

• Heart Failure

Interventions

• PROCEDURE

No Results Yet

NCT04764188 | ACTIVE_NOT_RECRUITING

800 participants

An Observational Study to Evaluate the Real-World Clinical Management and Outcomes of ALK-Positive Advanced NSCLC Participants Treated With Alectinib

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-10

Start Date:

2021-05-10

Completion:

2027-05-10

Conditions

• NSCLC

Interventions

• DRUG

No Results Yet

NCT04754061 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

20 participants

PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2024-01-08

Completion:

2026-10-01

Conditions

• Depression, Anxiety
• Distress, Emotional

Interventions

• DRUG

No Results Yet

NCT04743310 | COMPLETED | PHASE2

50 participants

Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2021-09-30

Completion:

2025-03-06

Conditions

• Central Nervous System Tumor

Interventions

• DRUG
• DEVICE
• PROCEDURE

Results Available

NCT04736420 | COMPLETED

78605 participants

Replication of the EINSTEIN-DVT Anticoagulant Trial in Healthcare Claims Data

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-10

Start Date:

2020-09-22

Completion:

2026-06-15

Conditions

• Venous Thromboembolism

Interventions

• DRUG

No Results Yet

NCT04717050 | COMPLETED | NA

64 participants

Reducing Metabolic Dysregulation in Obese Latina Breast Cancer Survivors Using Physical Activity

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2021-09-23

Completion:

2025-01-21

Conditions

• Breast Cancer
• Coronary Artery Disease
• Stroke
• Type2 Diabetes

Interventions

• BEHAVIORAL

Results Available

NCT04712097 | ACTIVE_NOT_RECRUITING | PHASE3

478 participants

A Study Evaluating the Efficacy and Safety of Mosunetuzumab in Combination With Lenalidomide in Comparison to Rituximab in Combination With Lenalidomide With a US Extension of Mosunetuzumab in Combination With Lenalidomide in Participants With Follicular Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2021-10-27

Completion:

2026-06-03

Conditions

• Relapsed or Refractory Follicular Lymphoma

Interventions

• DRUG

No Results Yet

NCT04711824 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

41 participants

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2022-03-09

Completion:

2026-07-31

Conditions

• Breast Cancer
• Brain Metastases, Adult

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04699838 | ACTIVE_NOT_RECRUITING | PHASE2

30 participants

Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2021-04-20

Completion:

2026-07-31

Conditions

• Extensive Stage Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT04684940 | COMPLETED | PHASE1/PHASE2

10 participants

Safety, Tolerability, and Efficacy Study of Valoctocogene Roxaparvovec in Hemophilia A With Active or Prior Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-12-10

Completion:

2026-04-20

Conditions

• Hemophilia A With Inhibitor
• Hemophilia A With Anti Factor VIII

Interventions

• BIOLOGICAL

No Results Yet

NCT04638894 | ACTIVE_NOT_RECRUITING

140 participants

Variability in ASD (Adult Spinal Deformity) Value

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-10

Start Date:

2021-06-01

Completion:

2026-11-01

Conditions

• Hospital Costs

Interventions

• PROCEDURE

No Results Yet

NCT04588233 | RECRUITING | NA

80 participants

Melatonin Adolescent Research Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2021-09-15

Completion:

2027-05-31

Conditions

• Sleep Disorders in Children

Interventions

• DIETARY_SUPPLEMENT
• OTHER

No Results Yet

NCT04566900 | ACTIVE_NOT_RECRUITING | NA

112 participants

Neurofeedback to Improve Working Memory in Mild Cognitive Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2021-01-01

Completion:

2026-06-30

Conditions

• Mild Cognitive Impairment

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04559139 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

186 participants

Comparison of Chemotherapy Before and After Surgery Versus After Surgery Alone for the Treatment of Gallbladder Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2021-02-24

Completion:

2028-07-01

Conditions

• Stage II Gallbladder Cancer AJCC v8
• Stage IIA Gallbladder Cancer AJCC v8
• Stage IIB Gallbladder Cancer AJCC v8
• Stage III Gallbladder Cancer AJCC v8
• Stage IIIA Gallbladder Cancer AJCC v8
• Stage IIIB Gallbladder Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04548609 | TERMINATED | NA

6 participants

Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2021-01-25

Completion:

2025-03-05

Conditions

• Obsessive-Compulsive Disorder
• Pediatric Psychiatric Disorder

Interventions

• DEVICE

Results Available

NCT04533763 | COMPLETED | NA

341 participants

Living WELL: A Web-Based Program for Ovarian Cancer Survivors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-09-30

Completion:

2026-01-07

Conditions

• Ovarian Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT04482309 | ACTIVE_NOT_RECRUITING | PHASE2

477 participants

A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-08-18

Completion:

2027-03-23

Conditions

• Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer
• Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer

Interventions

• DRUG

No Results Yet

NCT04465643 | COMPLETED | PHASE1

13 participants

Neoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath Tumor

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2021-06-08

Completion:

2025-07-30

Conditions

• Nerve Sheath Tumors

Interventions

• DRUG

No Results Yet

NCT04452591 | ACTIVE_NOT_RECRUITING | PHASE3

190 participants

Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-Guerin

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-10-27

Completion:

2030-06-16

Conditions

• Non Muscle Invasive Bladder Cancer
• High-grade Ta/ T1 Papillary Disease Bladder Cancer

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04450316 | TERMINATED | PHASE2

29 participants

Low-dose Naltrexone for Bladder Pain Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-10-08

Completion:

2022-06-04

Conditions

• Bladder Pain Syndrome
• Interstitial Cystitis

Interventions

• DRUG

Results Available

NCT04431479 | ACTIVE_NOT_RECRUITING

211 participants

Predicting the Quality of Response to Specific Treatments in Patients With cGVHD, PQRST Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-10

Start Date:

2020-06-29

Completion:

2027-07-01

Conditions

• Chronic Graft Versus Host Disease

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04419519 | ACTIVE_NOT_RECRUITING | PHASE2

81 participants

Assessing Minimal Residual Disease by Next- Generation Sequencing to Minimize Exposure in People With CLL or SLL Who Have Been Treated With Venetoclax

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-05-13

Completion:

2027-05-31

Conditions

• Chronic Lymphocytic Leukemia (CLL)
• Small Lymphocytic Lymphoma (SLL)

Interventions

• DRUG

No Results Yet

NCT04403295 | COMPLETED | NA

281 participants

Collaborative Specialty Care for Gulf War Illness

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-08-24

Completion:

2026-06-11

Conditions

• Gulf War Illness

Interventions

• BEHAVIORAL

No Results Yet

NCT04392206 | RECRUITING | PHASE1

15 participants

AMSC for Reducing Anastomotic Stenosis in Primary Arteriovenous Anastomoses

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-05-15

Completion:

2026-12-31

Conditions

• End Stage Renal Disease

Interventions

• DRUG

No Results Yet

NCT04373551 | COMPLETED | NA

67 participants

WeExPAnd: PrEP Demonstration Project Among Women at Risk for HIV Infection - Preexposure Prophylaxis (PrEP)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2022-03-07

Completion:

2024-06-30

Conditions

• HIV-infection/AIDS

Interventions

• BEHAVIORAL

Results Available

NCT04348643 | WITHDRAWN | PHASE1/PHASE2

0 participants

Safety and Efficacy of CEA-Targeted CAR-T Therapy for Relapsed/Refractory CEA+ Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-02-20

Completion:

2023-12-31

Conditions

• Solid Tumor
• Lung Cancer
• Colorectal Cancer
• Liver Cancer
• Pancreatic Cancer
• Gastric Cancer
• Breast Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT04316117 | ACTIVE_NOT_RECRUITING | PHASE2

138 participants

Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-09-15

Completion:

2027-08-31

Conditions

• Anatomic Stage IV Breast Cancer AJCC v8
• Hormone Receptor Positive Breast Carcinoma
• Metastatic Breast Carcinoma
• Prognostic Stage IV Breast Cancer AJCC v8

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04302051 | WITHDRAWN

0 participants

Assessment of Fatty Liver With Thermo-acoustic Device

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-10

Start Date:

2023-11-02

Completion:

2026-07-09

Conditions

• NASH
• NAFLD
• Non-alcoholic Fatty Liver
• Non-Alcoholic Fatty Liver Disease
• Non-alcoholic Steatohepatitis
• Fatty Liver
• Fatty Liver Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04284436 | ACTIVE_NOT_RECRUITING | NA

370 participants

Study in Parkinson Disease of Exercise

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2021-08-30

Completion:

2027-07-31

Conditions

• Parkinson Disease

Interventions

• BEHAVIORAL

No Results Yet

NCT04266249 | ACTIVE_NOT_RECRUITING | PHASE2

2175 participants

CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-03-13

Completion:

2027-10-31

Conditions

• Anatomic Stage II Breast Cancer AJCC v8
• Anatomic Stage IIA Breast Cancer AJCC v8
• Anatomic Stage IIB Breast Cancer AJCC v8
• Anatomic Stage IIIA Breast Cancer AJCC v8
• Invasive Breast Carcinoma
• Prognostic Stage II Breast Cancer AJCC v8
• Prognostic Stage IIA Breast Cancer AJCC v8
• Prognostic Stage IIB Breast Cancer AJCC v8
• Prognostic Stage IIIA Breast Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL
• RADIATION

No Results Yet

NCT04258319 | ENROLLING_BY_INVITATION | NA

90 participants

Sub-Hertz Analysis of Viscoelasticity of Limbs in Patients With Lymphedema

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-07-06

Completion:

2028-06-30

Conditions

• Lymphedema

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04248452 | ACTIVE_NOT_RECRUITING | PHASE3

314 participants

Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-05-26

Completion:

2028-03-31

Conditions

• Clinical Stage IV Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IV Gastric Cancer AJCC v8
• Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IVA Gastric Cancer AJCC v8
• Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8
• Clinical Stage IVB Gastric Cancer AJCC v8
• Metastatic Esophageal Adenocarcinoma
• Metastatic Gastric Adenocarcinoma
• Oligometastatic Esophageal Adenocarcinoma
• Oligometastatic Gastric Adenocarcinoma
• Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IV Gastric Cancer AJCC v8
• Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8
• Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8

Interventions

• DRUG
• RADIATION

No Results Yet

NCT04233866 | ACTIVE_NOT_RECRUITING | PHASE2

176 participants

Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-08-26

Completion:

2026-03-02

Conditions

• Metastatic Pancreatic Adenocarcinoma
• Stage IV Pancreatic Cancer AJCC v8

Interventions

• DRUG
• OTHER

No Results Yet

NCT04201223 | COMPLETED | NA

752 participants

Family Lifestyles, Actions, and Risk Education Intervention: Version 2

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-04-07

Completion:

2025-01-28

Conditions

• Melanoma
• Child

Interventions

• BEHAVIORAL

Results Available

NCT04191304 | ACTIVE_NOT_RECRUITING | PHASE3

134 participants

A Phase III Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-07-20

Completion:

2025-05-07

Conditions

• Hypereosinophilic Syndrome

Interventions

• BIOLOGICAL

Results Available

NCT04168372 | ACTIVE_NOT_RECRUITING | NA

35 participants

Fructose: Substrate, Stimulus, or Both?

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2019-09-15

Completion:

2026-12-31

Conditions

• Insulin Resistance
• Insulin Sensitivity
• Pre Diabetes

Interventions

• OTHER

No Results Yet

NCT04166318 | ACTIVE_NOT_RECRUITING | PHASE2

252 participants

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2020-01-02

Completion:

2029-12-31

Conditions

• Anal Basaloid Carcinoma
• Anal Canal Cloacogenic Carcinoma
• Anal Canal Squamous Cell Carcinoma
• Anal Margin Squamous Cell Carcinoma
• Stage I Anal Cancer AJCC v8
• Stage IIA Anal Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• OTHER
• RADIATION

No Results Yet

NCT04143724 | RECRUITING | PHASE2

99 participants

Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-10

Start Date:

2019-11-07

Completion:

2028-01-31

Conditions

• Beta-Thalassemia

Interventions

• DRUG

No Results Yet