Clinical Trials

NCT06618508 | NOT_YET_RECRUITING | NA

25 participants

Manual Debridement vs Phototherapeutic Keratectomy in the Treatment of Corneal Basement Membrane Dystrophy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2026-10-31

Completion:

2027-10-31

Conditions

• Epithelial Basement Membrane Dystrophy

Interventions

• PROCEDURE

No Results Yet

NCT06617598 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:

2026-07-08

No Results Yet

NCT06613672 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:

2026-07-08

No Results Yet

NCT06610396 | ACTIVE_NOT_RECRUITING

30 participants

Ex Onc SLED: A Study Utilizing A Weighted Sled for Horizontal Resistance Training

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-08

Start Date:

2024-06-18

Completion:

2026-12-18

Conditions

• Cancer

No Results Yet

NCT06602232 | ACTIVE_NOT_RECRUITING | PHASE1

81 participants

A Study of DR-01 in Subjects With Alopecia Areata and Vitiligo

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-10-30

Completion:

2027-05-31

Conditions

• Alopecia Areata
• Vitiligo

Interventions

• DRUG

No Results Yet

NCT06594913 | RECRUITING

20000 participants

Eating Disorders Genetics Initiative 2

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-08

Start Date:

2024-10-28

Completion:

2027-09-01

Conditions

• Anorexia Nervosa
• Bulimia Nervosa
• Binge-Eating Disorder
• Avoidant Restrictive Food Intake Disorder

Interventions

• OTHER

No Results Yet

NCT06585488 | TERMINATED | PHASE1

47 participants

A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-12-13

Completion:

2026-04-23

Conditions

• Metastatic Solid Tumors
• Advanced Non-squamous Non-small-cell Lung Cancer
• Advanced Colorectal Cancer
• Advanced Pancreatic Ductal Adenocarcinoma
• Advanced Gastric Cancer
• Advanced Gastroesophageal Junction Cancer
• Advanced Esophageal Adenocarcinoma

Interventions

• DRUG

No Results Yet

NCT06578780 | COMPLETED

110 participants

Design and Delivery Preferences for Exercise Intervention in People With Spinal Cord Injury

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-08

Start Date:

2024-08-27

Completion:

2026-05-31

Conditions

• Spinal Cord Injuries

No Results Yet

NCT06551116 | RECRUITING

200 participants

QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-08

Start Date:

2024-10-10

Completion:

2029-09-01

Conditions

• HER2-positive Metastatic Breast Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06547710 | RECRUITING

66 participants

Primary Tumor Resection for M1a Stage Lung Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-08

Start Date:

2024-04-01

Completion:

2026-12-31

Conditions

• Lung Cancer Metastatic
• Surgical Resection

No Results Yet

NCT06544811 | RECRUITING | NA

416 participants

American Indian Smokefree Native RCT

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2025-04-14

Completion:

2029-01-01

Conditions

• Smoking Cessation

Interventions

• OTHER

No Results Yet

NCT06532773 | RECRUITING | NA

60 participants

Mindfulness Intervention for Sleep Disturbance and Symptom Management in Hematologic Cancer Patients During and After Inpatient Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2026-01-14

Completion:

2029-06-30

Conditions

• Hematologic Malignancy

Interventions

• BEHAVIORAL

No Results Yet

NCT06529120 | COMPLETED | NA

15 participants

Adaptation and Pilot Testing of a Mindfulness-Based Insomnia and Symptom Management Intervention for Women With Breast Cancer Receiving Treatment in Rural Medically Underserved Areas

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2025-09-11

Completion:

2026-06-02

Conditions

• Breast Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT06497504 | ACTIVE_NOT_RECRUITING | PHASE2

153 participants

Study of Bepirovirsen in Participants Living With Human Immunodeficiency Virus and Chronic Hepatitis B Virus Infection (B-Focus)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-09-17

Completion:

2027-04-22

Conditions

• Hepatitis B

Interventions

• DRUG

No Results Yet

NCT06492746 | RECRUITING | NA

120 participants

Personal BP - CAI Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-06-03

Completion:

2027-01-31

Conditions

• Blood Pressure

Interventions

• DEVICE

No Results Yet

NCT06486454 | RECRUITING

5000 participants

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-08

Start Date:

2024-10-14

Completion:

2026-11-30

Conditions

• Liver Neoplasms
• Primary Liver Cancer
• Secondary Liver Cancer
• Tumor Liver
• Benign Liver Tumor

Interventions

• DEVICE

No Results Yet

NCT06478212 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

51 participants

Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2025-01-22

Completion:

2027-11-30

Conditions

• IDH1-mutant Glioma
• IDH2-mutant Glioma

Interventions

• DRUG

No Results Yet

NCT06476613 | COMPLETED | NA

80 participants

Permissive Hypotension After Cardiac Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-04-20

Completion:

2025-07-01

Conditions

• Surgery

Interventions

• OTHER

No Results Yet

NCT06476600 | COMPLETED | NA

42 participants

Opioid-based Versus Opioid-free Anaesthesia for Laparoscopic Cholecystectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-07-01

Completion:

2024-10-15

Conditions

• Surgical Procedure, Unspecified
• Laparoscopic Cholecystectomy

Interventions

• DRUG

No Results Yet

NCT06476288 | ENROLLING_BY_INVITATION | NA

20 participants

RIC (Remote Ischemic Conditioning) in Older Individuals

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-09-30

Completion:

2026-11-30

Conditions

• Old Age
• Mobility Limitation
• Debility

Interventions

• OTHER

No Results Yet

NCT06444269 | RECRUITING | PHASE2

53 participants

Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-10-11

Completion:

2027-07-01

Conditions

• Breast Cancer

Interventions

• RADIATION
• DRUG

No Results Yet

NCT06436235 | RECRUITING

40 participants

Kidney Stone Inflammation

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-08

Start Date:

2024-06-30

Completion:

2028-07-01

Conditions

• Kidney Stone
• Stone, Kidney

No Results Yet

NCT06424769 | ENROLLING_BY_INVITATION | NA

900 participants

Improving Outcomes and Reducing Disparities for Patients With Inflammatory Bowel Disease Through Epidemiology and Enhanced Disease Management

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-07-24

Completion:

2028-09-30

Conditions

• Inflammatory Bowel Diseases
• Crohn Disease
• Ulcerative Colitis
• Colitis

Interventions

• OTHER

No Results Yet

NCT06422299 | NOT_YET_RECRUITING | NA

60 participants

Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Young Adult Couples

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2026-10-01

Completion:

2027-10-01

Conditions

• Alcohol Drinking
• Cannabis Use
• Couples

Interventions

• BEHAVIORAL

No Results Yet

NCT06411756 | COMPLETED | NA

21 participants

Physical Activity Centers Empowerment

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-08-14

Completion:

2026-05-18

Conditions

• Colorectal Neoplasms

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06404112 | COMPLETED | PHASE2

469 participants

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-07-31

Completion:

2026-02-26

Conditions

• Long COVID
• Long COVID-19
• Sleep Disturbance

Interventions

• DEVICE
• DRUG

No Results Yet

NCT06404060 | COMPLETED | NA

360 participants

RECOVER-ENERGIZE Platform Protocol_Appendix A (Exercise Intolerance)

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-07-17

Completion:

2026-03-10

Conditions

• Long COVID
• Long Covid19
• Long Covid-19

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT06386263 | COMPLETED

22 participants

HER-TEMPO - Real World Treatment-related Outcomes on T-DXd in Canada

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-08

Start Date:

2024-04-22

Completion:

2025-07-07

Conditions

• Unresectable Breast Cancer
• Metastatic Breast Cancer
• HER2-low Expressing Breast Cancer
• HER2-positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT06384196 | RECRUITING | NA

138 participants

Identity-Based Transdiagnostic Therapy for Young People With Anxiety and Depression

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2025-05-02

Completion:

2026-06-30

Conditions

• Depression
• Anxiety

Interventions

• BEHAVIORAL

No Results Yet

NCT06370351 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

12 participants

A Phase I/II Clinical Trial With SENS-501 in Children Suffering From Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-06-21

Completion:

2027-07-31

Conditions

• OTOF Gene Mutation
• DFNB9
• Congenital Deafness
• Hearing Disorders
• Ear Diseases
• Otorhinolaryngologic Diseases
• Deafness
• Hearing Loss, Sensorineural

Interventions

• COMBINATION_PRODUCT

No Results Yet

NCT06364709 | COMPLETED | NA

22 participants

Criterion-learning Based Naming Treatment in Aphasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-10-15

Completion:

2026-04-28

Conditions

• Aphasia

Interventions

• BEHAVIORAL

No Results Yet

NCT06361472 | RECRUITING | NA

94 participants

Contextual Factors-Enriched Standard Care on Mechanical Neck Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-05-02

Completion:

2027-04-30

Conditions

• Neck Pain

Interventions

• OTHER
• BEHAVIORAL

No Results Yet

NCT06352632 | RECRUITING | PHASE3

20000 participants

ACT-GLOBAL Adaptive Platform Trial for Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-09-26

Completion:

2034-09-30

Conditions

• Stroke

Interventions

• DRUG
• OTHER

No Results Yet

NCT06352619 | RECRUITING | NA

2000 participants

Third Enhanced Control of Hypertension and Thrombectomy Stroke Domain Within ACT-GLOBAL Adaptive Platform Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-10-11

Completion:

2027-12-31

Conditions

• Ischemic Stroke, Acute

Interventions

• OTHER

No Results Yet

NCT06349772 | RECRUITING | EARLY_PHASE1

130 participants

Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-11-01

Completion:

2027-11-01

Conditions

• Post Operative Pain

Interventions

• DRUG

No Results Yet

NCT06329141 | COMPLETED | PHASE2

99 participants

A Study to Assess the Efficacy and Safety of Vutiglabridin in Early Parkinson's Disease Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-07-22

Completion:

2025-12-16

Conditions

• Parkinson Disease

Interventions

• DRUG

No Results Yet

NCT06320405 | RECRUITING | PHASE1/PHASE2

38 participants

Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-05-21

Completion:

2027-04-01

Conditions

• Advanced Malignant Solid Neoplasm
• Metastatic Malignant Solid Neoplasm
• Recurrent Malignant Solid Neoplasm
• Refractory Malignant Solid Neoplasm

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT06304233 | ACTIVE_NOT_RECRUITING

120 participants

The Protein Disrupted in Schizophrenia 1 (DISC1) as a Novel Biomarker for Cardiac Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-07-08

Start Date:

2023-12-13

Completion:

2026-12-31

Conditions

• Heart Diseases
• Heart; Functional Disturbance
• Schizophrenia

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT06299826 | COMPLETED | PHASE2

375 participants

A Phase IIb Study of AZD5462 in Patients With Chronic Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-06-04

Completion:

2026-02-10

Conditions

• Chronic Heart Failure

Interventions

• DRUG

No Results Yet

NCT06288191 | RECRUITING | PHASE2

20 participants

Neoadjuvant Nivolumab and Relatlimab in Cutaneous Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-07-08

Start Date:

2024-06-21

Completion:

2026-09-30

Conditions

• Cutaneous Squamous Cell Carcinoma

Interventions

• DRUG

No Results Yet