The Protein Disrupted in Schizophrenia 1 (DISC1) as a Novel Biomarker for Cardiac Disease
NCT06304233 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 120
Last updated 2025-06-22
Summary
To study the association between DISC1 RNA expression levels and cardiac function in patients with schizophrenia.
Conditions
- Heart Diseases
- Heart; Functional Disturbance
- Schizophrenia
Interventions
- DIAGNOSTIC_TEST
-
Echocardiography
ultrasound assessment of heart structure, volume and function
- DIAGNOSTIC_TEST
-
Cardiac Magnetic Resonance Imaging
MRI assessment of heart structure, volume, function and tissue characteristics
- DIAGNOSTIC_TEST
-
Electrocardiography
Assessment of cardiac rhythm and electrical activity
- OTHER
-
Blood sampling
To measure DISC1 mRNA expression and other potential biomarkers
Sponsors & Collaborators
-
St. Olavs Hospital
collaborator OTHER -
Norwegian University of Science and Technology
lead OTHER
Principal Investigators
-
Morten A Høydal, PhD · Norwegian University of Science and Technology
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-12-13
- Primary Completion
- 2026-12-31
- Completion
- 2038-06-30
Countries
- Norway
Study Locations
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