Clinical Trials

NCT06008093 | ACTIVE_NOT_RECRUITING | PHASE2

103 participants

A Study to Investigate the Efficacy of Durvalumab Plus Tremelimumab in Combination With Chemotherapy Compared With Pembrolizumab in Combination With Chemotherapy in Metastatic NSCLC Patients With Non-squamous Histology Who Have Mutations and/or Co-mutations in STK11, KEAP1, or KRAS

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2024-04-04
Completion:: 2026-10-23

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG

No Results Yet

NCT06001762 | ACTIVE_NOT_RECRUITING | PHASE2

90 participants

TRADE: Dose Escalation Tolerability of Abemaciclib in HR+ HER2- Early Stage Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-10-05
Completion:: 2025-01-22

Conditions

Breast Cancer
Early-stage Breast Cancer
High Risk Breast Carcinoma

Interventions

DRUG

Results Available

NCT06001684 | COMPLETED | PHASE1

19 participants

Phase 1 Study of IBR854 in Locally Advanced Or Metastatic Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-09-01
Completion:: 2024-12-26

Conditions

Solid Tumors

Interventions

BIOLOGICAL

No Results Yet

NCT06001268 | ACTIVE_NOT_RECRUITING | NA

80 participants

Support Through Remote Observation and Nutrition Guidance Program (STRONG-PCS)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-08-14
Completion:: 2027-08-31

Conditions

Pancreatic Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT05990075 | COMPLETED | NA

47 participants

An eHealth Intervention to Increase Depression Treatment Initiation and Adherence Among Veterans Referred for Mental Health Services

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-09-13
Completion:: 2024-09-30

Conditions

Depression

Interventions

BEHAVIORAL

Results Available

NCT05979311 | ACTIVE_NOT_RECRUITING | PHASE3

307 participants

A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2024-02-21
Completion:: 2026-04-15

Conditions

HIV
HIV Infections

Interventions

DRUG

No Results Yet

NCT05975905 | TERMINATED | PHASE2

113 participants

A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study).

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-10-17
Completion:: 2025-03-05

Conditions

Pulmonary Arterial Hypertension

Interventions

BIOLOGICAL

Results Available

NCT05968755 | NOT_YET_RECRUITING | NA

145 participants

Leveraging Chatbot to Improve PrEP in the Southern United States

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2026-07-20
Completion:: 2027-02-28

Conditions

HIV Prevention
PrEP Awareness
PrEP Uptake

Interventions

DEVICE
OTHER

No Results Yet

NCT05962359 | RECRUITING | NA

700 participants

Neural Prediction to Enhance Language

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-01-23
Completion:: 2027-07-23

Conditions

Bilateral Sensorineural Hearing Loss
Speech and Language Development Delay Due to Hearing Loss
Social Communication

Interventions

BEHAVIORAL

No Results Yet

NCT05953038 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

40 participants

LSD Occupancy of the Serotonin 2A Receptor in the Human Brain

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-11-08
Completion:: 2027-12-31

Conditions

Basic Science

Interventions

DRUG

No Results Yet

NCT05947916 | RECRUITING | NA

240 participants

Real Time Continuous Glucose Monitoring System in T2DM With Pregnacy

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2024-01-30
Completion:: 2025-12-31

Conditions

Type2diabetes
Pregnancy Related
Continuous Glucose Monitoring
Time in Range
Pregnancy Outcome

Interventions

DEVICE

No Results Yet

NCT05943119 | RECRUITING | PHASE2

52 participants

Phase II Study of Intensity Modulated Radiotherapy in Dose Painting for Sinus Carcinomas After Endoscopic Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2024-03-11
Completion:: 2028-01-31

Conditions

Tumor, Solid

Interventions

RADIATION

No Results Yet

NCT05941481 | COMPLETED | PHASE2

21 participants

Neoadjuvant Chemo-hypoRT Plus PD-1 Antibody (Tislelizumab) in Resectable LA-G/GEJ

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-06-10
Completion:: 2025-03-15

Conditions

Gastric or Gastroesophageal Junction Adenocarcinoma

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05930509 | COMPLETED | NA

40 participants

Home-based Non-invasive Brain Stimulation for Treatment-resistant Depression Feasibility, Efficacy and Biomarker of Treatment Response

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-06-15
Completion:: 2025-09-30

Conditions

Major Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT05909462 | COMPLETED | NA

60 participants

Comparison of the Effects Suprascapular Nerve Block and Intra-articular Shoulder Injection

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-01-21
Completion:: 2023-04-24

Conditions

Adhesive Capsulitis

Interventions

DRUG

No Results Yet

NCT05890222 | COMPLETED | NA

816 participants

IMPlementation of Evidence Based Facility and Community Interventions to Reduce the Treatment Gap for depRESSion

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-11-01
Completion:: 2025-11-18

Conditions

Depression

Interventions

BEHAVIORAL

No Results Yet

NCT05879887 | ACTIVE_NOT_RECRUITING | NA

64 participants

An Optimization Pilot to Optimize An Early Palliative Care Intervention for Advanced Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2024-08-15
Completion:: 2026-08-01

Conditions

Chronic Illness
Heart Failure - NYHA II - IV

Interventions

BEHAVIORAL

No Results Yet

NCT05862467 | COMPLETED | NA

28 participants

A Pilot Participatory Program Evaluation of a Virtual Trauma Support Program for Autistic Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-10-26
Completion:: 2025-02-12

Conditions

Autism
Trauma
Posttraumatic Stress Disorder
Posttraumatic Stress Symptom

Interventions

BEHAVIORAL

Results Available

NCT05852041 | RECRUITING | EARLY_PHASE1

40 participants

rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-06-07
Completion:: 2026-05-13

Conditions

Prostate Adenocarcinoma
Stage I Prostate Cancer AJCC v8
Stage IIA Prostate Cancer AJCC v8
Stage IIB Prostate Cancer AJCC v8

Interventions

PROCEDURE
GENETIC
OTHER

No Results Yet

NCT05851430 | RECRUITING

1000 participants

Galvanize Prospective/Retrospective Pulsed Electric Field Device Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-02
Start Date:: 2025-06-23
Completion:: 2028-06-30

Conditions

Soft Tissue Lesion

Interventions

DEVICE

No Results Yet

NCT05835362 | COMPLETED | NA

252 participants

Improving the Outcomes of Adolescents With ADHD Via a Pre-visit Question Prompt List/Video Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-03-22
Completion:: 2025-11-30

Conditions

ADHD

Interventions

BEHAVIORAL

Results Available

NCT05830708 | COMPLETED | NA

58 participants

The Efficacy of Probiotics for the Treatment of Alcohol Use Disorder Among Adult Males

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2022-06-01
Completion:: 2024-06-30

Conditions

Alcohol Use Disorder

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05827016 | ACTIVE_NOT_RECRUITING | PHASE3

1230 participants

A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-06-22
Completion:: 2029-03-15

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT05824767 | COMPLETED | PHASE4

42 participants

Serum Biomarkers to Predict Response to Angiotensin II in Septic Shock

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-04-17
Completion:: 2025-03-12

Conditions

Septic Shock
Vasodilatory Shock

Interventions

DRUG

Results Available

NCT05824585 | COMPLETED | PHASE1

17 participants

DZD8586 in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-05-15
Completion:: 2025-06-30

Conditions

Lymphoma, Non-Hodgkin

Interventions

DRUG

No Results Yet

NCT05819541 | COMPLETED | PHASE2

90 participants

Treating Exacerbations of Asthma With Oral Montelukast in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-10-20
Completion:: 2026-03-26

Conditions

Status Asthmaticus

Interventions

DRUG

No Results Yet

NCT05817812 | COMPLETED | PHASE3

93 participants

A Study Evaluating Physical Activity and Joint Health in Severe Haemophilia A Patients ≥12 Years Treated Once Weekly With Efanesoctocog Alfa

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-07-31
Completion:: 2026-06-02

Conditions

Hemophilia A, Severe

Interventions

DRUG

No Results Yet

NCT05797870 | TERMINATED | PHASE2

16 participants

Selective Internal Radiation Therapy and 188Re-SSS Lipiodol Treatment for Liver Cancer (Lip-Re2)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2024-02-14
Completion:: 2025-01-13

Conditions

Hepatocellular Carcinoma Non-resectable

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05787470 | RECRUITING

120 participants

State of Hormones Impact Nociceptive Expression

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-03-01
Completion:: 2027-07-31

Conditions

Pain
Gender Identity

Interventions

BEHAVIORAL
DIAGNOSTIC_TEST

No Results Yet

NCT05785767 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

149 participants

A Study to Learn if a Combination of Fianlimab and Cemiplimab Versus Cemiplimab Alone is More Effective for Adult Participants With Advanced Non-Small Cell Lung Cancer (NSCLC)

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-06-30
Completion:: 2027-09-28

Conditions

Advanced Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05766579 | ACTIVE_NOT_RECRUITING | NA

64 participants

Comparison Trial Between Elastic-compressive Stockings at 21 Versus 32 mmHg

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2019-04-02
Completion:: 2026-12-30

Conditions

Vascular Surgical Procedures

Interventions

DEVICE

No Results Yet

NCT05756387 | RECRUITING

100 participants

Improving Chronic Nocturnal Noninvasive Ventilation: a Multimodality Approach

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-02
Start Date:: 2024-12-01
Completion:: 2028-12-01

Conditions

Chronic Respiratory Failure
Non-invasive Ventilation

Interventions

DEVICE

No Results Yet

NCT05756335 | COMPLETED | NA

24 participants

The Brain Metabolism of Unpredictable Signals

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2024-04-05
Completion:: 2026-02-12

Conditions

Healthy

Interventions

BEHAVIORAL

No Results Yet

NCT05748483 | COMPLETED | PHASE3

545 participants

Comparative Study of Oral Atogepant Versus Oral Topiramate to Assess Adverse Events in Adult Participants With Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-10-07
Completion:: 2025-04-28

Conditions

Migraine

Interventions

DRUG

Results Available

NCT05748314 | ACTIVE_NOT_RECRUITING

80 participants

Marfan Syndrome and Quality of Life of Pediatric Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-01-09
Completion:: 2026-12-31

Conditions

Rare Diseases
Pediatric Disorder

Interventions

OTHER

No Results Yet

NCT05726058 | RECRUITING | NA

150 participants

Ocular Blood Flow Imaging for Glaucoma Assessment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-03-30
Completion:: 2027-12-31

Conditions

Glaucoma

Interventions

DEVICE

No Results Yet

NCT05724563 | ACTIVE_NOT_RECRUITING | PHASE2

58 participants

Domvanalimab and Zimberelimab in Advanced Liver Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-06-12
Completion:: 2027-12-31

Conditions

Hepatobiliary Cancer
Liver Cancer
Cholangiocarcinoma
Hepatocellular Carcinoma

Interventions

DRUG

No Results Yet

NCT05710406 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

1 participants

Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-08-16
Completion:: 2034-06-01

Conditions

Colon Adenocarcinoma
Microsatellite Stable Colon Carcinoma
Stage IIB Colon Cancer AJCC v8
Stage IIC Colon Cancer AJCC v8
Stage III Colon Cancer AJCC v8

Interventions

DRUG
BIOLOGICAL
PROCEDURE
OTHER

No Results Yet

NCT05709574 | ACTIVE_NOT_RECRUITING | PHASE2

11 participants

Tadalafil Effect + Chemotherapy in Resectable Gastric/GEJ Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2023-04-20
Completion:: 2026-06-03

Conditions

Gastric Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT05709457 | COMPLETED | NA

18131 participants

Long Term Effects Of a Maternal Cash Transfer Experiment

Study Type:: INTERVENTIONAL
Last Updated:: 2026-07-02
Start Date:: 2021-05-15
Completion:: 2023-07-31

Conditions

Maternal Health Services
Outcome Assessment

Interventions

BEHAVIORAL

No Results Yet