Clinical Trials

NCT04867590 | RECRUITING | NA

140 participants

A Study Comparing the Effectiveness of EndoRotor Versus Radiofrequency in Treating Barrett's Esophagus

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2022-03-25

Completion:

2031-07-25

Conditions

• Barrett Esophagus
• Dysplasia

Interventions

• DEVICE

No Results Yet

NCT04849884 | COMPLETED | NA

77 participants

To Evaluate the Performance of the CORI™ KNEE TENSIONER as an Accessory to the CORI™ Surgical System.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2022-03-30

Completion:

2025-06-04

Conditions

• Arthroplasty
• Replacement
• Knee

Interventions

• DEVICE

Results Available

NCT04838301 | ACTIVE_NOT_RECRUITING | PHASE2

100 participants

Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2023-08-15

Completion:

2026-11-18

Conditions

• Alzheimer Dementia
• Late Onset Alzheimer Disease
• Neurodegenerative Diseases

Interventions

• DRUG
• OTHER

No Results Yet

NCT04823858 | ACTIVE_NOT_RECRUITING

176 participants

3Spine Lumbar Fusion Real World Evidence Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-30

Start Date:

2021-05-25

Completion:

2025-12-23

Conditions

• Lumbar Spine Degeneration

Interventions

• DEVICE

No Results Yet

NCT04806386 | COMPLETED | NA

31 participants

The Role of Fiber in the Prevention and Treatment of Fecal Incontinence

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2021-07-21

Completion:

2024-12-11

Conditions

• Fecal Incontinence
• Irritable Bowel Syndrome With Diarrhea

Interventions

• DIETARY_SUPPLEMENT

Results Available

NCT04802161 | ACTIVE_NOT_RECRUITING | PHASE2

49 participants

Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2022-08-24

Completion:

2024-11-21

Conditions

• Acute Myeloid Leukemia
• Acute Myeloid Leukemia Post Cytotoxic Therapy
• Acute Myeloid Leukemia With Multilineage Dysplasia
• Chronic Myelomonocytic Leukemia
• Myelodysplastic Syndrome
• Myeloproliferative Neoplasm

Interventions

• PROCEDURE
• DRUG

Results Available

NCT04788277 | ACTIVE_NOT_RECRUITING

810 participants

Investigation Into Detection of Prostate Cancer Using Voided Urine (Prostate VPAC)

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-30

Start Date:

2020-02-26

Completion:

2026-06-01

Conditions

• Prostate Carcinoma

Interventions

• PROCEDURE

No Results Yet

NCT04788043 | TERMINATED | PHASE2

8 participants

Study of Magrolimab and Pembrolizumab in Relapsed or Refractory Classic Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2022-06-21

Completion:

2024-10-11

Conditions

• Hodgkin Lymphoma
• Classic Hodgkin Lymphoma
• Relapsed Classical Hodgkin Lymphoma
• Refractory Classic Hodgkin Lymphoma

Interventions

• PROCEDURE
• DRUG

Results Available

NCT04771416 | SUSPENDED | PHASE1/PHASE2

24 participants

Study of Safety, Tolerability and Efficacy of PBKR03 in Pediatric Subjects With Early Infantile Krabbe Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2022-02-24

Completion:

2027-01-31

Conditions

• Leukodystrophy, Globoid Cell

Interventions

• BIOLOGICAL

No Results Yet

NCT04766515 | RECRUITING

6000 participants

Observational Prospective Study of Immune Checkpoint Inhibitors for Solid Neoplasms

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-30

Start Date:

2020-09-01

Completion:

2023-08-31

Conditions

• Cancer

No Results Yet

NCT04751383 | TERMINATED | PHASE1

12 participants

Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2021-08-31

Completion:

2024-09-30

Conditions

• High Risk Neuroblastoma
• Recurrent Neuroblastoma
• Recurrent Osteosarcoma
• Refractory Neuroblastoma
• Resectable Osteosarcoma

Interventions

• PROCEDURE
• BIOLOGICAL

Results Available

NCT04740307 | COMPLETED | PHASE2

116 participants

Safety and Efficacy of Coformulated Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib (E7080/MK-7902) in Advanced Hepatocellular Carcinoma (MK-1308A-004)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2021-03-16

Completion:

2025-07-29

Conditions

• Advanced Hepatocellular Carcinoma

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT04713475 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

26 participants

Study of Safety, Tolerability and Efficacy of PBGM01 in Pediatric Participants With GM1 Gangliosidosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2021-03-17

Completion:

2028-02-29

Conditions

• GM1 Gangliosidosis
• GM1 Gangliosidosis, Type I
• GM1 Gangliosidosis, Type 2
• Beta-Galactosidase-1 (GLB1) Deficiency

Interventions

• BIOLOGICAL

No Results Yet

NCT04708288 | RECRUITING

198 participants

To Evaluate the Safety and Clinical Performance of the ARCHIMEDES Biodegradable Biliary and Pancreatic Stent

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-30

Start Date:

2020-10-03

Completion:

2027-06-30

Conditions

• Obstructed Biliary and Pancreatic Duct

Interventions

• DEVICE

No Results Yet

NCT04691570 | COMPLETED | PHASE2

7 participants

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ANX005 in Participants With Warm Autoimmune Hemolytic Anemia (wAIHA)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2021-11-10

Completion:

2023-01-17

Conditions

• Warm Autoimmune Hemolytic Anemia (wAIHA)

Interventions

• DRUG

Results Available

NCT04680000 | ACTIVE_NOT_RECRUITING | NA

716 participants

Chronic Pain Management In Primary Care Using Behavioral Health Consultants

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2021-08-17

Completion:

2026-06-30

Conditions

• Chronic Pain

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT04655963 | ACTIVE_NOT_RECRUITING | NA

20 participants

Brain Stimulation for Improving Cognition in Chronic Stroke (NEPTUNE)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2021-01-14

Completion:

2026-07-30

Conditions

• Chronic Stroke

Interventions

• DEVICE

No Results Yet

NCT04645589 | COMPLETED

69 participants

Evaluating the Safety of Myfortic (Mycophenolate Sodium) in Patients With Lupus Nephritis

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-30

Start Date:

2021-03-16

Completion:

2025-08-13

Conditions

• Lupus Nephritis

Interventions

• DRUG

No Results Yet

NCT04613440 | ACTIVE_NOT_RECRUITING | NA

524 participants

FaCT Trial (Facilitated Cascade Testing Trial)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2021-07-21

Completion:

2025-09-18

Conditions

• BRCA1 Mutation
• BRCA2 Mutation

Interventions

• OTHER

No Results Yet

NCT04609878 | COMPLETED | PHASE3

2274 participants

Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (KALOS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-12-15

Completion:

2025-03-21

Conditions

• Asthma

Interventions

• DRUG

Results Available

NCT04519619 | RECRUITING

480 participants

Study to Learn More About Safety of Aflibercept Injection in Japanese Patients With Neovascular Glaucoma (NVG)

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-30

Start Date:

2020-11-27

Completion:

2027-06-30

Conditions

• Neovascular Glaucoma

Interventions

• DRUG

No Results Yet

NCT04506437 | COMPLETED | NA

76 participants

Foster Care Mental Health Family Navigator

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-08-20

Completion:

2025-04-01

Conditions

• Mental Health

Interventions

• BEHAVIORAL

Results Available

NCT04482647 | ACTIVE_NOT_RECRUITING | NA

100 participants

Breathing Techniques and Meditation for Health Care Workers During COVID-19 Pandemic

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-06-17

Completion:

2020-11-05

Conditions

• COVID-19 Infection

Interventions

• OTHER
• PROCEDURE

Results Available

NCT04476862 | ACTIVE_NOT_RECRUITING

35 participants

Cerliponase Alfa Observational Study in the US

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-30

Start Date:

2020-08-19

Completion:

2030-08-31

Conditions

• Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04441619 | COMPLETED | NA

128 participants

Mechanisms and Modulation of Pain Modulatory Capacity

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-11-30

Completion:

2026-03-10

Conditions

• Musculoskeletal Pain

Interventions

• BEHAVIORAL

No Results Yet

NCT04432571 | COMPLETED | NA

880 participants

ADAPT for Adolescents Adolescents

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2021-04-06

Completion:

2025-09-13

Conditions

• HIV/AIDS

Interventions

• BEHAVIORAL

No Results Yet

NCT04430517 | COMPLETED | EARLY_PHASE1

21 participants

Effects of Nicotinamide Riboside on Bioenergetics and Oxidative Stress in Mild Cognitive Impairment/Alzheimer's Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2022-03-02

Completion:

2026-04-29

Conditions

• Mild Cognitive Impairment
• Mild Alzheimer Disease

Interventions

• DRUG

No Results Yet

NCT04419857 | COMPLETED | NA

39 participants

A Trial to Determine Weight Gain Benefits of Caloric Supplementation for NAS Infants

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-12-04

Completion:

2025-05-01

Conditions

• Neonatal Abstinence Syndrome

Interventions

• DIETARY_SUPPLEMENT

Results Available

NCT04409782 | COMPLETED | NA

260 participants

Education About Health and Cancer Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-10-31

Completion:

2023-11-03

Conditions

• Cancer

Interventions

• OTHER

Results Available

NCT04402931 | COMPLETED | NA

150 participants

Redo Surgery or Transcatheter Valve-in-Valve for Mitral Bioprosthetic Dysfunction (SURViV)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-02-17

Completion:

2024-02-01

Conditions

• Mitral Prosthetic Valve Stenosis and Regurgitation

Interventions

• PROCEDURE

No Results Yet

NCT04376229 | RECRUITING

5000 participants

Proton Radiation Therapy Registry

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-30

Start Date:

2020-04-07

Completion:

2030-12-31

Conditions

• Cancer, Therapy-Related

Interventions

• OTHER

No Results Yet

NCT04369599 | ENROLLING_BY_INVITATION | NA

15 participants

Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q System

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-08-11

Completion:

2026-11-30

Conditions

• Acute Respiratory Distress Syndrome
• COVID-19

Interventions

• DEVICE

No Results Yet

NCT04365868 | TERMINATED | PHASE2/PHASE3

357 participants

Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-06-25

Completion:

2025-03-11

Conditions

• Prevention of Esophageal Varices
• NASH - Nonalcoholic Steatohepatitis
• Cirrhosis

Interventions

• DRUG

Results Available

NCT04294498 | COMPLETED | PHASE2

30 participants

Durvalumab for Advanced Hepatocellular Carcinoma in Patients With Active Chronic Hepatitis B Virus Infection

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-11-02

Completion:

2024-09-01

Conditions

• Advanced Hepatocellular Carcinoma

Interventions

• DRUG

No Results Yet

NCT04287868 | COMPLETED | PHASE1/PHASE2

51 participants

Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-06-09

Completion:

2022-07-26

Conditions

• Cervical Cancer
• HPV Cancers
• Anal Cancer
• Oropharyngeal Cancer
• Vulvar, Vaginal, Penile, Rectal Cancer

Interventions

• BIOLOGICAL

Results Available

NCT04272073 | COMPLETED | NA

28 participants

A High-PRotein Mediterranean Diet and Resistance Exercise for Cardiac Rehabilitation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2022-05-09

Completion:

2024-02-28

Conditions

• Cardiovascular Diseases
• Sarcopenic Obesity

Interventions

• OTHER

No Results Yet

NCT04259255 | COMPLETED

74 participants

Radicava® (Edaravone) Findings in Biomarkers From ALS (REFINE-ALS)

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-30

Start Date:

2019-10-21

Completion:

2023-11-24

Conditions

• Amyotrophic Lateral Sclerosis
• ALS

Interventions

• DRUG

No Results Yet

NCT04253626 | COMPLETED | PHASE3

83 participants

Comparison of Oral Ferrous Sulfate to Intravenous Ferumoxytol in Antepartum Iron Deficiency Anemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2021-01-21

Completion:

2024-07-01

Conditions

• Pregnancy Related
• Anemia, Iron Deficiency

Interventions

• DRUG

Results Available

NCT04216719 | ACTIVE_NOT_RECRUITING | NA

3440 participants

Facilitating Opioid Care Connections

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-03-18

Completion:

2026-12-30

Conditions

• Opioid Court Model
• Medication to Treat Opioid Use Disorder
• Opioid Use

Interventions

• BEHAVIORAL

No Results Yet

NCT04214834 | ACTIVE_NOT_RECRUITING | PHASE3

189 participants

Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-30

Start Date:

2020-09-28

Completion:

2024-01-31

Conditions

• Neonatal Opioid Withdrawal Syndrome

Interventions

• DRUG

Results Available