Clinical Trials

NCT05856136 | RECRUITING | PHASE4

69 participants

A Study to Investigate of the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-06-19

Completion:

2025-12-08

Conditions

• Respiratory Function Loss
• Respiratory Complication

Interventions

• DRUG

No Results Yet

NCT05854160 | RECRUITING | NA

30 participants

Stimulation-Induced Changes in Fronto-Limbic Network

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-03-01

Completion:

2026-02-28

Conditions

• Epilepsy
• Mental Disorders

Interventions

• PROCEDURE

No Results Yet

NCT05853601 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

30 participants

Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-10-17

Completion:

2027-05-31

Conditions

• Acute Kidney Injury
• HIE

Interventions

• DRUG

No Results Yet

NCT05837611 | WITHDRAWN | NA

0 participants

Contingency Management Using Deposit Contract to Reduce Drinking

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-06-10

Completion:

2025-05-31

Conditions

• Alcohol Abuse
• Alcohol Intervention
• Transdermal Alcohol Monitoring
• Contingency Management
• Deposit Contract

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05829655 | RECRUITING | EARLY_PHASE1

75 participants

Measuring Acute Drug Demand in Humans

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-08-08

Completion:

2028-01-01

Conditions

• Opioid Use Disorder
• Opioid Dependence

Interventions

• DRUG

No Results Yet

NCT05829330 | COMPLETED | NA

46 participants

Ambulatory Versus Inpatient Initiation of Home Mechanical Ventilation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-09-20

Completion:

2026-05-01

Conditions

• Amyotrophic Lateral Sclerosis

Interventions

• OTHER

No Results Yet

NCT05826925 | RECRUITING | NA

30 participants

Optimizing Cardiovascular Preventive Care for Women Following Hypertensive Disorders of Pregnancy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2026-07-15

Completion:

2027-08-31

Conditions

• Hypertension, Pregnancy Induced
• Hypertension Complicating Pregnancy
• Preeclampsia
• Cardiovascular Diseases
• Patient Engagement

Interventions

• OTHER

No Results Yet

NCT05825625 | ACTIVE_NOT_RECRUITING | PHASE2

35 participants

NeoTRACK - Dissection of IO Efficacy in NSCLC by Longitudinal tracKing

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-05-26

Completion:

2026-12-01

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05820087 | ACTIVE_NOT_RECRUITING | NA

67 participants

The HistoSonics Edison™ System for Treatment of Primary Solid Renal Tumors Using Histotripsy (#HOPE4KIDNEY)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2024-01-04

Completion:

2025-09-04

Conditions

• Renal Cancer
• Tumor, Solid
• Kidney Cancer
• Tumor
• Tumor, Benign

Interventions

• DEVICE

No Results Yet

NCT05812911 | TERMINATED | NA

1470 participants

Comparing High-flow Nasal Cannula Oxygen and Noninvasive Ventilation to Standard Oxygenation in Non-selected ICU Patients Admitted for Hypoxemic ARF

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-05-23

Completion:

2026-03-14

Conditions

• Acute Respiratory Failure

Interventions

• PROCEDURE

No Results Yet

NCT05795465 | RECRUITING | PHASE2

52 participants

A Study of GEn-1124 in Subjects With Acute Respiratory Distress Syndrome (ARDS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-04-04

Completion:

2026-10-31

Conditions

• Respiratory Distress Syndrome, Acute

Interventions

• DRUG

No Results Yet

NCT05774678 | RECRUITING | PHASE3

126 participants

Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Nanomechanical Biomarker Evaluation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-04-05

Completion:

2026-11-01

Conditions

• Breast Cancer

Interventions

• RADIATION
• OTHER

No Results Yet

NCT05734638 | ACTIVE_NOT_RECRUITING | NA

90 participants

Stress and Blood Pressure Management for Caregivers

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-09-11

Completion:

2026-03-12

Conditions

• Hypertension
• Stress, Psychological

Interventions

• BEHAVIORAL

No Results Yet

NCT05731128 | ACTIVE_NOT_RECRUITING | PHASE2

68 participants

A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-01-12

Completion:

2026-05-13

Conditions

• Colitis Ulcerative

Interventions

• DRUG

No Results Yet

NCT05726370 | RECRUITING | PHASE2

28 participants

Preoperative Pembrolizumab and Chemotherapy in Resectable, Recurrent HNSCC

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-05-20

Completion:

2027-12-31

Conditions

• Head and Neck Squamous Cell Carcinoma
• Head and Neck Cancer
• Resectable Head and Neck Squamous Cell Carcinoma
• Recurrent Head and Neck Squamous Cell Carcinoma
• Second Primary Squamous Cell Carcinoma of the Head and Neck

Interventions

• DRUG

No Results Yet

NCT05684965 | RECRUITING | PHASE1/PHASE2

358 participants

XTX301 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-05-11

Completion:

2028-09-30

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05652153 | RECRUITING | NA

80 participants

Inhibitory Mechanisms of Negative Urgency in Adolescent Suicidal Behavior

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2024-05-25

Completion:

2028-01-31

Conditions

• Suicidal Behavior
• Suicidal Ideation
• Negative Urgency
• Cortical Inhibition
• Depression

Interventions

• OTHER

No Results Yet

NCT05646381 | RECRUITING | PHASE2

502 participants

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2024-03-07

Completion:

2030-03-12

Conditions

• Aortic Stenosis

Interventions

• DRUG

No Results Yet

NCT05615441 | COMPLETED | NA

54 participants

Effect of Nociception Level Monitoring During Remimazolam-based Total Intravenous Anesthesia on Intraoperative Opioid Requirements and Postoperative Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-07-17

Completion:

2025-11-21

Conditions

• Adult Patients Aged 19-64, Scheduled for Elective Arthroscopic Knee Surgery

Interventions

• DEVICE

No Results Yet

NCT05609578 | ACTIVE_NOT_RECRUITING | PHASE2

90 participants

Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-11-22

Completion:

2026-09-30

Conditions

• Advanced NSCLC
• Metastatic Lung Cancer

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT05590689 | RECRUITING | PHASE1/PHASE2

34 participants

Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain Tumor

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-11-09

Completion:

2028-01-31

Conditions

• Glioblastoma

Interventions

• DRUG
• RADIATION

No Results Yet

NCT05588245 | RECRUITING | NA

540 participants

Trial of Community-based Patient Navigation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2024-01-25

Completion:

2027-06-30

Conditions

• Pregnancy Related

Interventions

• BEHAVIORAL

No Results Yet

NCT05585801 | ACTIVE_NOT_RECRUITING | NA

500 participants

Continuous Glucose Monitoring in Intensive Care Unit

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-11-01

Completion:

2026-12-31

Conditions

• Blood Glucose
• Critical Care

Interventions

• DEVICE
• DIAGNOSTIC_TEST

No Results Yet

NCT05584670 | RECRUITING | PHASE1/PHASE2

542 participants

A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-11-29

Completion:

2027-01-19

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05584228 | NOT_YET_RECRUITING | NA

150 participants

Medical Treatment Versus Surgery in Stricturing Small Bowel Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2026-10-01

Completion:

2030-04-01

Conditions

• Crohn Disease

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05562778 | RECRUITING | NA

150 participants

Chatbot to Maximize Hereditary Cancer Genetic Risk Assessment

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-01-15

Completion:

2027-12-31

Conditions

• Gynecologic Cancer
• Hereditary Cancer Syndrome

Interventions

• OTHER

No Results Yet

NCT05555732 | ACTIVE_NOT_RECRUITING | PHASE3

1170 participants

Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-01-11

Completion:

2029-05-11

Conditions

• Metastatic Non Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05551234 | COMPLETED

10 participants

Reciprocal Benefit by Intergenerational Meetings

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-01

Completion:

2026-05-19

Conditions

• Isolation, Social

Interventions

• OTHER

No Results Yet

NCT05534984 | TERMINATED | PHASE3

719 participants

Study of Tecovirimat for Human Mpox Virus

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-08

Completion:

2024-10-23

Conditions

• MPOX

Interventions

• DRUG

Results Available

NCT05529732 | COMPLETED | NA

68 participants

The Effect of Mobile Education on Anxiety and Activities of Daily Living

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-09-01

Completion:

2022-03-01

Conditions

• Thyroidectomy
• Postoperative Anxiety
• Benign Thyroid Disease

Interventions

• OTHER

No Results Yet

NCT05498207 | RECRUITING | NA

500 participants

Identification of Biomarkers for Stress Vulnerability and Resilience

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-08-23

Completion:

2029-12-31

Conditions

• Healthy

Interventions

• BEHAVIORAL

No Results Yet

NCT05490303 | COMPLETED | NA

90 participants

HeartGuide: Preliminary Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-09

Completion:

2023-02-09

Conditions

• Cardiac Disease

Interventions

• OTHER

No Results Yet

NCT05485545 | WITHDRAWN | NA

0 participants

Asynchrony in Operated Tetralogy of Fallot

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-01

Completion:

2024-09-01

Conditions

• Tetralogy of Fallot

Interventions

• OTHER

No Results Yet

NCT05484895 | COMPLETED | NA

1800 participants

Mobile Health Intervention to Increase HIV Testing and Linkage to Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-12-15

Completion:

2024-10-10

Conditions

• HIV

Interventions

• BEHAVIORAL

Results Available

NCT05443451 | COMPLETED | NA

12 participants

BETTY: BEnign Prostatic Hyperplasia Transperineal Targeted Microwave therapY

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-08

Completion:

2023-10-05

Conditions

• Prostate Hyperplasia

Interventions

• DEVICE

No Results Yet

NCT05441267 | ACTIVE_NOT_RECRUITING | PHASE4

21296 participants

A Study of Cardiovascular Events iN Diabetes Plus

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-03-13

Completion:

2028-08-17

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

No Results Yet

NCT05435859 | ENROLLING_BY_INVITATION | NA

60 participants

Functional Organization of the Superior Temporal Gyrus for Speech Perception

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-08-16

Completion:

2027-07-31

Conditions

• Epilepsy
• Brain Tumor
• Speech

Interventions

• BEHAVIORAL

No Results Yet

NCT05433454 | COMPLETED | NA

97854 participants

Impact of Outreach on Medicaid Enrollment

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-05-17

Completion:

2026-05-31

Conditions

• Health Insurance

Interventions

• OTHER

No Results Yet

NCT05401097 | RECRUITING | PHASE2

125 participants

IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-13

Completion:

2027-09-30

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05368207 | COMPLETED | NA

1 participants

Pembrolizumab in Small Cell Carcinoma of Ovary - Hypercalcemic Type Patient

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-12-06

Completion:

2025-10-16

Conditions

• Small Cell Carcinoma, Hypercalcaemic Type
• Ovarian Cancer

Interventions

• DRUG

No Results Yet