Clinical Trials

NCT05684965 | RECRUITING | PHASE1/PHASE2

358 participants

XTX301 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-05-11

Completion:

2028-09-30

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05652153 | RECRUITING | NA

80 participants

Inhibitory Mechanisms of Negative Urgency in Adolescent Suicidal Behavior

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2024-05-25

Completion:

2028-01-31

Conditions

• Suicidal Behavior
• Suicidal Ideation
• Negative Urgency
• Cortical Inhibition
• Depression

Interventions

• OTHER

No Results Yet

NCT05646381 | RECRUITING | PHASE2

502 participants

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2024-03-07

Completion:

2030-03-12

Conditions

• Aortic Stenosis

Interventions

• DRUG

No Results Yet

NCT05615441 | COMPLETED | NA

54 participants

Effect of Nociception Level Monitoring During Remimazolam-based Total Intravenous Anesthesia on Intraoperative Opioid Requirements and Postoperative Pain

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-07-17

Completion:

2025-11-21

Conditions

• Adult Patients Aged 19-64, Scheduled for Elective Arthroscopic Knee Surgery

Interventions

• DEVICE

No Results Yet

NCT05609578 | ACTIVE_NOT_RECRUITING | PHASE2

90 participants

Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-11-22

Completion:

2026-09-30

Conditions

• Advanced NSCLC
• Metastatic Lung Cancer

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT05592990 | COMPLETED | PHASE2

45 participants

A Study to Investigate the Safety, Tolerability and Preliminary Efficacy of NGI226 Microparticles in Patients With Achilles Tendinopathy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-06-14

Completion:

2026-02-03

Conditions

• Achilles Tendinopathy

Interventions

• DRUG

No Results Yet

NCT05590689 | RECRUITING | PHASE1/PHASE2

34 participants

Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain Tumor

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-11-09

Completion:

2028-01-31

Conditions

• Glioblastoma

Interventions

• DRUG
• RADIATION

No Results Yet

NCT05588245 | RECRUITING | NA

540 participants

Trial of Community-based Patient Navigation

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2024-01-25

Completion:

2027-06-30

Conditions

• Pregnancy Related

Interventions

• BEHAVIORAL

No Results Yet

NCT05585801 | ACTIVE_NOT_RECRUITING | NA

500 participants

Continuous Glucose Monitoring in Intensive Care Unit

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-11-01

Completion:

2026-12-31

Conditions

• Blood Glucose
• Critical Care

Interventions

• DEVICE
• DIAGNOSTIC_TEST

No Results Yet

NCT05584670 | RECRUITING | PHASE1/PHASE2

542 participants

A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-11-29

Completion:

2027-01-19

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05584228 | NOT_YET_RECRUITING | NA

150 participants

Medical Treatment Versus Surgery in Stricturing Small Bowel Crohn's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2026-10-01

Completion:

2030-04-01

Conditions

• Crohn Disease

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05562778 | RECRUITING | NA

150 participants

Chatbot to Maximize Hereditary Cancer Genetic Risk Assessment

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-01-15

Completion:

2027-12-31

Conditions

• Gynecologic Cancer
• Hereditary Cancer Syndrome

Interventions

• OTHER

No Results Yet

NCT05555732 | ACTIVE_NOT_RECRUITING | PHASE3

1170 participants

Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-01-11

Completion:

2029-05-11

Conditions

• Metastatic Non Small Cell Lung Cancer

Interventions

• DRUG

No Results Yet

NCT05551234 | COMPLETED

10 participants

Reciprocal Benefit by Intergenerational Meetings

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-01

Completion:

2026-05-19

Conditions

• Isolation, Social

Interventions

• OTHER

No Results Yet

NCT05534984 | TERMINATED | PHASE3

719 participants

Study of Tecovirimat for Human Mpox Virus

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-08

Completion:

2024-10-23

Conditions

• MPOX

Interventions

• DRUG

Results Available

NCT05529732 | COMPLETED | NA

68 participants

The Effect of Mobile Education on Anxiety and Activities of Daily Living

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-09-01

Completion:

2022-03-01

Conditions

• Thyroidectomy
• Postoperative Anxiety
• Benign Thyroid Disease

Interventions

• OTHER

No Results Yet

NCT05498207 | RECRUITING | NA

500 participants

Identification of Biomarkers for Stress Vulnerability and Resilience

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-08-23

Completion:

2029-12-31

Conditions

• Healthy

Interventions

• BEHAVIORAL

No Results Yet

NCT05490303 | COMPLETED | NA

90 participants

HeartGuide: Preliminary Study

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-09

Completion:

2023-02-09

Conditions

• Cardiac Disease

Interventions

• OTHER

No Results Yet

NCT05485545 | WITHDRAWN | NA

0 participants

Asynchrony in Operated Tetralogy of Fallot

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-01

Completion:

2024-09-01

Conditions

• Tetralogy of Fallot

Interventions

• OTHER

No Results Yet

NCT05484895 | COMPLETED | NA

1800 participants

Mobile Health Intervention to Increase HIV Testing and Linkage to Care

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-12-15

Completion:

2024-10-10

Conditions

• HIV

Interventions

• BEHAVIORAL

Results Available

NCT05443451 | COMPLETED | NA

12 participants

BETTY: BEnign Prostatic Hyperplasia Transperineal Targeted Microwave therapY

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-08

Completion:

2023-10-05

Conditions

• Prostate Hyperplasia

Interventions

• DEVICE

No Results Yet

NCT05441267 | ACTIVE_NOT_RECRUITING | PHASE4

21296 participants

A Study of Cardiovascular Events iN Diabetes Plus

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-03-13

Completion:

2028-08-17

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

No Results Yet

NCT05435859 | ENROLLING_BY_INVITATION | NA

60 participants

Functional Organization of the Superior Temporal Gyrus for Speech Perception

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-08-16

Completion:

2027-07-31

Conditions

• Epilepsy
• Brain Tumor
• Speech

Interventions

• BEHAVIORAL

No Results Yet

NCT05433454 | COMPLETED | NA

97854 participants

Impact of Outreach on Medicaid Enrollment

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-05-17

Completion:

2026-05-31

Conditions

• Health Insurance

Interventions

• OTHER

No Results Yet

NCT05401097 | RECRUITING | PHASE2

125 participants

IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-09-13

Completion:

2027-09-30

Conditions

• Acute Myeloid Leukemia

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT05368207 | COMPLETED | NA

1 participants

Pembrolizumab in Small Cell Carcinoma of Ovary - Hypercalcemic Type Patient

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-12-06

Completion:

2025-10-16

Conditions

• Small Cell Carcinoma, Hypercalcaemic Type
• Ovarian Cancer

Interventions

• DRUG

No Results Yet

NCT05367505 | ACTIVE_NOT_RECRUITING | NA

50 participants

Titanium Fusion Implant in Combination With Trans-iliac Screws for Insufficiency Fractures of the Pelvis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-01-09

Completion:

2027-06-07

Conditions

• Pelvic Fracture
• Insufficiency Fractures
• Mobility Limitation

Interventions

• DEVICE

No Results Yet

NCT05323955 | ACTIVE_NOT_RECRUITING | PHASE2

48 participants

Secondary BRain Metastases Prevention After Isolated Intracranial Progression on Trastuzumab/Pertuzumab or T-DM1 in Patients With aDvanced Human Epidermal Growth Factor Receptor 2+ brEast Cancer With the Addition of Tucatinib

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-03-23

Completion:

2026-11-30

Conditions

• Brain Metastases
• Human Epidermal Growth Factor 2 Positive Carcinoma of Breast
• Advanced Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05297773 | COMPLETED | NA

132 participants

Resistance vs. Aerobic Training on Breast Cancer Patients Undergoing Neoadjuvant Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-12-16

Completion:

2025-12-30

Conditions

• Breast Cancer

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT05200065 | COMPLETED | NA

60 participants

Thulium Laser Versus Bipolar Enucleation of the Prostate

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-01-01

Completion:

2022-11-01

Conditions

• Benign Prostatic Hyperplasia

Interventions

• PROCEDURE

No Results Yet

NCT05189223 | RECRUITING | NA

50 participants

A Brief Values Intervention to Support Veterans in Early Buprenorphine Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2023-09-01

Completion:

2027-03-31

Conditions

• Dependence, Opioid

Interventions

• BEHAVIORAL

No Results Yet

NCT05182372 | COMPLETED | NA

700 participants

Enhancing Digital CBT-I to Improve Adherence and Reduce Disparities

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-05-18

Completion:

2026-05-06

Conditions

• Insomnia

Interventions

• BEHAVIORAL

No Results Yet

NCT05174312 | COMPLETED | NA

100 participants

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve Decongestion Management System (DMS)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-07-11

Completion:

2025-01-10

Conditions

• Acute Decompensated Heart Failure

Interventions

• DEVICE
• DRUG

Results Available

NCT05166161 | ACTIVE_NOT_RECRUITING | PHASE3

200 participants

A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-02-14

Completion:

2026-06-30

Conditions

• Phenylketonuria

Interventions

• DRUG

No Results Yet

NCT05161195 | ACTIVE_NOT_RECRUITING | PHASE4

134 participants

Roll-over Study to Allow Continued Access to Ribociclib

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-07-07

Completion:

2030-06-28

Conditions

• Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT05152992 | ENROLLING_BY_INVITATION | NA

100 participants

Spatiotemporal Dynamics of the Human Emotion Network

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2015-04-20

Completion:

2026-06-30

Conditions

• Epilepsy
• Depression
• Anxiety
• Emotions

Interventions

• BEHAVIORAL

No Results Yet

NCT05117619 | ACTIVE_NOT_RECRUITING | NA

281 participants

The HOME Program for Individuals With Traumatic Brain Injury and Family Members

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-12-22

Completion:

2026-09-30

Conditions

• Brain Injuries, Traumatic

Interventions

• BEHAVIORAL

No Results Yet

NCT05109975 | TERMINATED | PHASE1

93 participants

A Study to Evaluate Safety and Preliminary Anti-tumor Activity of Debio 0123 as Monotherapy in Adult Participants With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2021-11-05

Completion:

2026-04-24

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT05107414 | COMPLETED

201 participants

Journey 2 Multi Center Kinematic Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-23

Start Date:

2021-05-15

Completion:

2024-12-31

Conditions

• Total Knee Arthroplasty

Interventions

• DEVICE

Results Available

NCT05085561 | COMPLETED | PHASE2

62 participants

The Symptomatic Cerebral Cavernous Malformation Trial of REC-994

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-23

Start Date:

2022-03-17

Completion:

2025-06-30

Conditions

• Cerebral Cavernous Malformation

Interventions

• DRUG

No Results Yet