Trial Outcomes & Findings for Journey 2 Multi Center Kinematic Study (NCT NCT05107414)
NCT ID: NCT05107414
Last Updated: 2026-06-23
Results Overview
The condylar rollback of the medial condyle will be observed at a single instance in time. Higher rollback indicates more motion and improved kinematics. Participants will have previously undergone a total knee arthroplasty but data cannot be collected on their preoperative kinematics. Outcome will be measured in \[mm\].
COMPLETED
201 participants
Baseline, at time of observation
2026-06-23
Participant Flow
Subjects recruited from surgeon's previously implanted population
One knee analyzed per participant
Participant milestones
| Measure |
Journey II Bi-Cruciate Stabilized
Participants who have been implanted with a Smith \& Nephew Journey II BCS TKA
|
Journey II Cruciate Retaining
Participants who have been implanted with a Smith \& Nephew Journey II CR TKA
|
Journey II Bi-Cruciate Retaining
Participants who have been implanted with a Smith \& Nephew Journey II BCR TKA
|
|---|---|---|---|
|
Overall Study
STARTED
|
101
|
71
|
29
|
|
Overall Study
COMPLETED
|
101
|
71
|
29
|
|
Overall Study
NOT COMPLETED
|
0
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Race and Ethnicity were not collected from any participant.
Baseline characteristics by cohort
| Measure |
Journey II Bi-Cruciate Stabilized
n=101 Participants
Participants who have been implanted with a Smith \& Nephew Journey II BCS TKA
|
Journey II Cruciate Retaining
n=71 Participants
Participants who have been implanted with a Smith \& Nephew Journey II CR TKA
|
Journey II Bi-Cruciate Retaining
n=29 Participants
Participants who have been implanted with a Smith \& Nephew Journey II BCR TKA
|
Total
n=201 Participants
Total of all reporting groups
|
|---|---|---|---|---|
|
Age, Continuous
|
65.2 years
STANDARD_DEVIATION 9.3 • n=101 Participants
|
67.9 years
STANDARD_DEVIATION 7.2 • n=71 Participants
|
64.9 years
STANDARD_DEVIATION 9.6 • n=29 Participants
|
66.0 years
STANDARD_DEVIATION 8.7 • n=201 Participants
|
|
Sex: Female, Male
Female
|
51 Participants
n=101 Participants
|
36 Participants
n=71 Participants
|
17 Participants
n=29 Participants
|
104 Participants
n=201 Participants
|
|
Sex: Female, Male
Male
|
50 Participants
n=101 Participants
|
35 Participants
n=71 Participants
|
12 Participants
n=29 Participants
|
97 Participants
n=201 Participants
|
|
Race and Ethnicity Not Collected
|
—
|
—
|
—
|
0 Participants
Race and Ethnicity were not collected from any participant.
|
PRIMARY outcome
Timeframe: Baseline, at time of observationThe condylar rollback of the medial condyle will be observed at a single instance in time. Higher rollback indicates more motion and improved kinematics. Participants will have previously undergone a total knee arthroplasty but data cannot be collected on their preoperative kinematics. Outcome will be measured in \[mm\].
Outcome measures
| Measure |
Journey II Bi-Cruciate Retaining
n=29 Participants
Participants who have been implanted with a Smith \& Nephew Journey II BCR TKA
|
Journey II Bi-Cruciate Stabilized
n=101 Participants
Participants who have been implanted with a Smith \& Nephew Journey II BCS TKA
|
Journey II Cruciate Retaining
n=71 Participants
Participants who have been implanted with a Smith \& Nephew Journey II CR TKA
|
|---|---|---|---|
|
Femorotibial Medial Condylar Rollback
|
-0.6 mm
Standard Deviation 4.4
|
-7.3 mm
Standard Deviation 3.9
|
1.1 mm
Standard Deviation 3.1
|
PRIMARY outcome
Timeframe: Baseline, at time of observationThe condylar rollback of the lateral condyle will be observed at a single instance in time. Higher rollback indicates more motion and improved kinematics. Participants will have previously undergone a total knee arthroplasty but data cannot be collected on their preoperative kinematics. Outcome will be measured in \[mm\].
Outcome measures
| Measure |
Journey II Bi-Cruciate Retaining
n=29 Participants
Participants who have been implanted with a Smith \& Nephew Journey II BCR TKA
|
Journey II Bi-Cruciate Stabilized
n=101 Participants
Participants who have been implanted with a Smith \& Nephew Journey II BCS TKA
|
Journey II Cruciate Retaining
n=71 Participants
Participants who have been implanted with a Smith \& Nephew Journey II CR TKA
|
|---|---|---|---|
|
Femorotibial Lateral Condylar Rollback
|
-5.2 mm
Standard Deviation 5.6
|
-13.5 mm
Standard Deviation 5.3
|
-4.5 mm
Standard Deviation 5.9
|
PRIMARY outcome
Timeframe: Baseline, at time of observationThe femorotibial axial rotation will be observed at a single instance in time. Higher rotation indicates more motion and improved kinematics. Participants will have previously undergone a total knee arthroplasty but data cannot be collected on their preoperative kinematics. Outcome will be measured in \[deg\].
Outcome measures
| Measure |
Journey II Bi-Cruciate Retaining
n=29 Participants
Participants who have been implanted with a Smith \& Nephew Journey II BCR TKA
|
Journey II Bi-Cruciate Stabilized
n=101 Participants
Participants who have been implanted with a Smith \& Nephew Journey II BCS TKA
|
Journey II Cruciate Retaining
n=71 Participants
Participants who have been implanted with a Smith \& Nephew Journey II CR TKA
|
|---|---|---|---|
|
Femorotibial Axial Rotation
|
6.1 degrees
Standard Deviation 4.7
|
7.6 degrees
Standard Deviation 5.5
|
6.8 degrees
Standard Deviation 6.2
|
PRIMARY outcome
Timeframe: Baseline, at time of observationThe femorotibial weight bearing flexion will be observed at a single instance in time. Higher flexion indicates greater range of motion and improved kinematics. Participants will have previously undergone a total knee arthroplasty but data cannot be collected on their preoperative kinematics. Outcome will be measured in \[deg\].
Outcome measures
| Measure |
Journey II Bi-Cruciate Retaining
n=29 Participants
Participants who have been implanted with a Smith \& Nephew Journey II BCR TKA
|
Journey II Bi-Cruciate Stabilized
n=101 Participants
Participants who have been implanted with a Smith \& Nephew Journey II BCS TKA
|
Journey II Cruciate Retaining
n=71 Participants
Participants who have been implanted with a Smith \& Nephew Journey II CR TKA
|
|---|---|---|---|
|
Femorotibial Weight Bearing Flexion
|
115.0 degrees
Standard Deviation 14.4
|
116.3 degrees
Standard Deviation 15.1
|
113.9 degrees
Standard Deviation 11.4
|
Adverse Events
Journey II Bi-Cruciate Stabilized
Journey II Cruciate Retaining
Journey II Bi-Cruciate Retaining
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place