Clinical Trials

NCT04149600 | ACTIVE_NOT_RECRUITING

1000 participants

Identification of Genetic Causes of Calcific Aortic Valve Disease

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-11

Start Date:

2018-09-25

Completion:

2027-06-30

Conditions

• Calcific Aortic Stenosis
• Calcific Aortic Stenosis - Bicuspid Valve
• Aortic Valve Disease
• Aortic Valve Calcification
• Aortic Diseases
• Aortic Aneurysm
• Aortic Valve Cusp Abnormality
• Aortic Valve Disease Mixed
• Aortic Valve Insufficiency

Interventions

• PROCEDURE

No Results Yet

NCT04106115 | RECRUITING | PHASE1/PHASE2

52 participants

DURvalumab in Combination With S-488210/S-488211 vAccine in Non-muscle Invasive Bladder CancEr

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2022-03-25

Completion:

2027-03-30

Conditions

• Bladder Cancer

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04104022 | COMPLETED | NA

82 participants

Prolonged Exposure Therapy for PTSD and Opioid Use Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-11-08

Completion:

2023-07-31

Conditions

• Post Traumatic Stress Disorder
• Opioid-use Disorder

Interventions

• BEHAVIORAL

Results Available

NCT04095923 | COMPLETED | NA

300 participants

A Social Media Game to Increase Physical Activity Among Older Adult Women

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-12-01

Completion:

2025-08-13

Conditions

• Aging

Interventions

• BEHAVIORAL

No Results Yet

NCT04023825 | WITHDRAWN | NA

0 participants

Analgesic Contribution of the Suprazygomatic Maxillary Nerve Block for Cleft Palate Surgery in Children

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-07-01

Completion:

2022-07-01

Conditions

• Cleft Palate
• Surgery

Interventions

• DRUG

No Results Yet

NCT04020276 | RECRUITING | NA

32 participants

OAR-Based, Dose Escalated SBRT With Real Time Adaptive MRI Guidance for Liver Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-11-04

Completion:

2026-12-31

Conditions

• Liver Metastases
• Stereotactic Body Radiation Therapy
• MRI-guided Treatment

Interventions

• RADIATION

No Results Yet

NCT04017650 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

38 participants

Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-06-14

Completion:

2027-12-30

Conditions

• BRAF NP_004324.2:p.V600E
• Metastatic Colon Adenocarcinoma
• Metastatic Microsatellite Stable Colorectal Carcinoma
• Metastatic Rectal Adenocarcinoma
• Progressive Disease
• Recurrent Colorectal Carcinoma
• Stage III Colorectal Cancer AJCC v8
• Stage IIIA Colorectal Cancer AJCC v8
• Stage IIIB Colorectal Cancer AJCC v8
• Stage IIIC Colorectal Cancer AJCC v8
• Stage IV Colorectal Cancer AJCC v8
• Stage IVA Colorectal Cancer AJCC v8
• Stage IVB Colorectal Cancer AJCC v8
• Stage IVC Colorectal Cancer AJCC v8
• Unresectable Colon Adenocarcinoma
• Unresectable Rectal Adenocarcinoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04013802 | RECRUITING | PHASE1

47 participants

TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT.

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2021-03-08

Completion:

2027-05-01

Conditions

• Viral Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT03983824 | ACTIVE_NOT_RECRUITING | PHASE1

48 participants

Testing the Addition of an Anti-cancer Drug, M3814, to the Usual Treatment (Mitoxantrone, Etoposide, and Cytarabine) for Relapsed or Refractory Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2020-05-05

Completion:

2027-06-30

Conditions

• Recurrent Acute Myeloid Leukemia
• Refractory Acute Myeloid Leukemia

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT03936478 | RECRUITING | PHASE2

30 participants

Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2022-05-16

Completion:

2027-01-31

Conditions

• Breast Cancer
• DCIS
• LCIS

Interventions

• RADIATION

No Results Yet

NCT03928457 | COMPLETED | NA

40 participants

Impact of Chronic Exposure to Radiofrequency Electromagnetic Fields on Neurophysiological Development in the Preterm Neonate

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-01-24

Completion:

2023-01-17

Conditions

• Preterm Infant
• Exposure to Radiofrequency

Interventions

• OTHER
• DIAGNOSTIC_TEST

No Results Yet

NCT03873610 | COMPLETED | NA

196 participants

Resiliency Training in Adolescents With NF1 and NF2

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-12-15

Completion:

2026-02-20

Conditions

• Neurofibromatoses

Interventions

• BEHAVIORAL

No Results Yet

NCT03866109 | TERMINATED | PHASE1/PHASE2

25 participants

A Study Evaluating Temferon in Patients With Glioblastoma & Unmethylated MGMT

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-03-05

Completion:

2026-05-27

Conditions

• Glioblastoma Multiforme

Interventions

• DRUG

No Results Yet

NCT03836976 | COMPLETED | NA

5 participants

Detection and Amelioration of Gamma Oscillation Abnormalities in Blast-Related Brain Injury

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-12-02

Completion:

2025-08-18

Conditions

• mTBI

Interventions

• OTHER

No Results Yet

NCT03822637 | TERMINATED | PHASE4

4 participants

The Effect of NAC on Lung Function and CT Mucus Score

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-02-20

Completion:

2025-02-21

Conditions

• Asthma

Interventions

• COMBINATION_PRODUCT

Results Available

NCT03763318 | COMPLETED | PHASE1/PHASE2

30 participants

A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-07-15

Completion:

2022-11-21

Conditions

• Acute-graft-versus-host Disease
• aGVHD
• GVHD
• GVHD, Acute

Interventions

• BIOLOGICAL

Results Available

NCT03735537 | COMPLETED | PHASE4

350 participants

Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic Acid

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2016-11-01

Completion:

2025-02-28

Conditions

• Osteogenesis Imperfecta

Interventions

• DRUG

No Results Yet

NCT03718780 | COMPLETED | NA

140 participants

Assessment of Continuous Measurement of Transcutaneous CO2 for Evaluation of Alveolar Dead Space During Exercise

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-02-22

Completion:

2023-12-31

Conditions

• Pulmonary Disease, Chronic Obstructive
• Lung Diseases, Interstitial
• Chronic Heart Failure
• Pulmonary Arterial Hypertension
• Hyperventilation Syndrome
• Healthy

Interventions

• OTHER

No Results Yet

NCT03682419 | COMPLETED

420 participants

Evaluation of Precision and Accuracy of INR Measurements in a Point of Care Device

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-11

Start Date:

2018-09-17

Completion:

2018-11-23

Conditions

• Deep Vein Thrombosis
• Atrial Fibrillation
• Post-Myocardial Infarction Syndrome
• Pulmonary Embolism
• Artificial Heart Device User
• Thrombophilia
• Antiphospholipid Syndrome

Interventions

• PROCEDURE

No Results Yet

NCT03682003 | COMPLETED

114 participants

Hepcidin: a Prognostic Marker of Morbidity and Mortality in Severe Sepsis?

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-11

Start Date:

2014-10-01

Completion:

2017-07-12

Conditions

• Severe Sepsis or Septic Shock

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03655509 | COMPLETED | NA

26 participants

Searching a Dysfunction of Corticotropic & Thyrotropin Axis During the Acute Phase of a Subarachnoid Hemorrhage Secondary to Spontaneous Rupture of Cerebral Aneurysm

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2015-08-22

Completion:

2016-12-31

Conditions

• Subarachnoid Hemorrhage

Interventions

• PROCEDURE

No Results Yet

NCT03652493 | COMPLETED | PHASE2

16 participants

Trial Evaluating the Efficacy of CARBOPLATIN in Metastatic Prostate Cancer With Gene Alterations in the Homologous Recombination Pathway

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2018-09-10

Completion:

2021-04-27

Conditions

• Castration-resistant Prostate Cancer
• Metastasis

Interventions

• DRUG

Results Available

NCT03622788 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

16 participants

Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2019-08-08

Completion:

2027-12-01

Conditions

• Acute Lymphoblastic Leukemia
• Acute Myeloid Leukemia
• Aplastic Anemia
• Bone Marrow Failure
• Chronic Lymphocytic Leukemia
• Chronic Myelogenous Leukemia, BCR-ABL1 Positive
• Follicular Lymphoma
• Hodgkin Lymphoma
• Mantle Cell Lymphoma
• Myelodysplastic Syndrome
• Myeloproliferative Neoplasm
• Non-Hodgkin Lymphoma
• Plasma Cell Myeloma

Interventions

• RADIATION
• BIOLOGICAL
• DRUG
• PROCEDURE

No Results Yet

NCT03609580 | RECRUITING | PHASE1/PHASE2

127 participants

Post-operative Urinary Retention (POUR) Following Thoracic Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2018-05-07

Completion:

2027-03-30

Conditions

• Urinary Retention

Interventions

• DRUG

No Results Yet

NCT03608293 | COMPLETED | NA

20 participants

Smoker Extracellular Vesicles Influence on Human Bronchial Epithelial Cells

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2012-01-01

Completion:

2013-07-31

Conditions

• Smokers
• Human Bronchial Epithelial Cells
• Lung Pathogenesis
• Biomarkers

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03582891 | ACTIVE_NOT_RECRUITING | NA

25 participants

The Motor Network in Parkinson's Disease and Dystonia: Mechanisms of Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2018-10-01

Completion:

2025-12-31

Conditions

• Parkinson Disease
• Dystonia

Interventions

• DEVICE
• DIAGNOSTIC_TEST

No Results Yet

NCT03535623 | COMPLETED | NA

44 participants

RIPC During Free Flap With Preoperative Radiotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2018-05-29

Completion:

2024-03-20

Conditions

• Ischemic Reperfusion Injury
• Other Reconstructive Surgery
• Radiotherapy

Interventions

• OTHER

Results Available

NCT03514108 | COMPLETED | PHASE4

1100 participants

DANHEART (H-HeFT and Met-HeFT)

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2018-03-01

Completion:

2025-12-31

Conditions

• Heart Failure
• Diabetes

Interventions

• DRUG

No Results Yet

NCT03511807 | RECRUITING | NA

100 participants

Acoustic and Electrical Stimulation for the Treatment of Tinnitus

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2017-01-01

Completion:

2032-11-30

Conditions

• Tinnitus

Interventions

• OTHER

No Results Yet

NCT03494075 | RECRUITING

2000 participants

MyPaTH Story Booth

Study Type:

OBSERVATIONAL

Last Updated:

2026-06-11

Start Date:

2016-03-31

Completion:

2030-06-30

Conditions

• Narrative Medicine

No Results Yet

NCT03488966 | ACTIVE_NOT_RECRUITING | NA

85 participants

Mindfulness Based Eating Awareness Training for Bariatric Surgery Patients

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2017-03-20

Completion:

2018-12-31

Conditions

• Obesity, Morbid
• Eating Disorder Symptom

Interventions

• BEHAVIORAL

No Results Yet

NCT03472755 | WITHDRAWN | NA

0 participants

Comparison of Direct Anterior and Posterior Surgical Approaches in Regards to the Patient' Physical Characteristics

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2018-03-23

Completion:

2019-12-20

Conditions

• Hip Arthropathy

Interventions

• OTHER

No Results Yet

NCT03438526 | RECRUITING | PHASE4

190 participants

The Basel BOMP-AID Randomized Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2022-01-03

Completion:

2027-12-31

Conditions

• Hypoactive Delirium

Interventions

• DRUG

No Results Yet

NCT03407638 | COMPLETED | NA

377373 participants

PRimary Care Opioid Use Disorders Treatment (PROUD) Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2018-02-28

Completion:

2020-02-29

Conditions

• Opioid-use Disorder

Interventions

• OTHER

Results Available

NCT03375307 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Testing Olaparib in Patients With Advanced or Metastatic (Cancer That Has Spread) Bladder Cancer and Other Genitourinary Tumors With DNA-Repair Genetic Changes

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2020-11-03

Completion:

2026-12-16

Conditions

• Advanced Bladder Carcinoma
• Advanced Genitourinary System Carcinoma
• Metastatic Bladder Carcinoma
• Metastatic Genitourinary System Carcinoma
• Stage III Bladder Cancer AJCC v8
• Stage IV Bladder Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG

No Results Yet

NCT03374657 | COMPLETED | PHASE1/PHASE2

12 participants

A First-in-human, Proof of Concept Study of CPK850 in Patients With RLBP1 Retinitis Pigmentosa

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2018-08-22

Completion:

2026-05-12

Conditions

• Retinitis Pigmentosa

Interventions

• BIOLOGICAL

No Results Yet

NCT03367156 | ACTIVE_NOT_RECRUITING | PHASE2

135 participants

Dexamethasone in Controlling Dyspnea in Patients With Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2017-12-04

Completion:

2021-05-05

Conditions

• Dyspnea
• Malignant Neoplasm

Interventions

• DRUG
• OTHER

Results Available

NCT03334006 | RECRUITING | PHASE2

200 participants

Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2017-11-20

Completion:

2027-09-30

Conditions

• Peritonitis
• Sepsis
• Septic Shock

Interventions

• DRUG

No Results Yet

NCT03321643 | ACTIVE_NOT_RECRUITING | PHASE1

24 participants

Testing the Addition of an Immunotherapy Agent, Atezolizumab, When Given With the Usual Chemo-Immunotherapy Drug Combination (Rituximab Plus Gemcitabine and Oxaliplatin) for Relapsed/Refractory (That Has Come Back or Not Responded to Treatment) Transformed Diffuse Large B-Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2018-09-18

Completion:

2027-06-30

Conditions

• Recurrent Diffuse Large B-Cell Lymphoma
• Recurrent Transformed Non-Hodgkin Lymphoma
• Refractory Diffuse Large B-Cell Lymphoma
• Refractory Transformed Non-Hodgkin Lymphoma
• Richter Syndrome
• Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT03224000 | ACTIVE_NOT_RECRUITING | PHASE2

90 participants

Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-06-11

Start Date:

2018-01-17

Completion:

2026-12-31

Conditions

• Malignant Neoplasms of Lip Oral Cavity and Pharynx
• Oropharyngeal Cancer

Interventions

• RADIATION
• PROCEDURE
• BEHAVIORAL

No Results Yet