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Identification of Genetic Causes of Calcific Aortic Valve Disease

NCT04149600 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2025-05-30

No results posted yet for this study

Summary

This study aims to identify the molecular genetic causes of the variability in development of calcific aortic valve disease in bicuspid and tricuspid aortic valves and their associated aortic dilation.

Conditions

  • Calcific Aortic Stenosis
  • Calcific Aortic Stenosis - Bicuspid Valve
  • Aortic Valve Disease
  • Aortic Valve Calcification
  • Aortic Diseases
  • Aortic Aneurysm
  • Aortic Valve Cusp Abnormality
  • Aortic Valve Disease Mixed
  • Aortic Valve Insufficiency

Interventions

PROCEDURE

Patients scheduled to undergo aortic valve replacement or aortic surgery at BIDMC will be approached for participation in this study.

Adult patients undergoing aortic valve replacement (AVR) and/or aortic resection will be enrolled.

Sponsors & Collaborators

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-09-25
Primary Completion
2027-06-30
Completion
2027-06-30

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04149600 on ClinicalTrials.gov