Clinical Trials

NCT04933851 | RECRUITING | PHASE2

250 participants

ACT1VATE: Addressing Emotional Distress to Improve Outcomes Among Diverse Adults With Type 1 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-10-25

Completion:

2027-03-31

Conditions

• Type 1 Diabetes

Interventions

• BEHAVIORAL

No Results Yet

NCT04933539 | ACTIVE_NOT_RECRUITING | PHASE2

14 participants

Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-10-31

Completion:

2026-08-31

Conditions

• Multiple Myeloma

Interventions

• DRUG
• BIOLOGICAL

No Results Yet

NCT04896008 | COMPLETED | PHASE3

173 participants

A Study of Sotatercept in Participants With PAH WHO FC III or FC IV at High Risk of Mortality (MK-7962-006/ZENITH)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-12-01

Completion:

2024-07-26

Conditions

• Pulmonary Arterial Hypertension

Interventions

• DRUG
• OTHER

Results Available

NCT04867681 | COMPLETED | NA

21 participants

Study of the Impact on the Therapeutic Alliance of a Short Initial Psychoeducation Programme in Patients With Early Schizophrenia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-12-08

Completion:

2026-05-19

Conditions

• Schizophrenia

Interventions

• BEHAVIORAL

No Results Yet

NCT04864886 | RECRUITING

300 participants

Metabolic Profiling of Immune Responses in Immune-mediated Diseases

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2021-08-10

Completion:

2027-06-30

Conditions

• Primary Immunodeficiency
• Psoriasis
• Atopic Dermatitis
• Immune-mediated Diseases

No Results Yet

NCT04858334 | RECRUITING | PHASE2

152 participants

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-06-22

Completion:

2027-10-31

Conditions

• Pancreatic Acinar Cell Carcinoma
• Pancreatic Adenosquamous Carcinoma
• Pancreatic Squamous Cell Carcinoma
• Resectable Pancreatic Acinar Cell Carcinoma
• Resectable Pancreatic Adenocarcinoma
• Resectable Pancreatic Adenosquamous Carcinoma
• Resectable Pancreatic Carcinoma

Interventions

• DRUG
• PROCEDURE

No Results Yet

NCT04855357 | COMPLETED | NA

452 participants

Smoke-free Home Intervention in Permanent Supportive Housing

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-01-24

Completion:

2025-03-31

Conditions

• Smoking Cessation
• Second Hand Tobacco Smoke

Interventions

• BEHAVIORAL

Results Available

NCT04854005 | ACTIVE_NOT_RECRUITING

78 participants

Use of Sentinel Lymph Node Biopsy in Patients With Early-Stage, Palpable Node-Positive HR+/HER2- Breast Cancer Having Upfront Surgery and Adjuvant Radiation

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2021-05-20

Completion:

2027-04-30

Conditions

• Breast Cancer

Interventions

• PROCEDURE

No Results Yet

NCT04838457 | COMPLETED | NA

30 participants

Telehealth Treatment of Veterans With Alcohol Misuse at Risk for Cardiovascular Disease

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-12-01

Completion:

2025-05-30

Conditions

• Alcohol Misuse
• Hypertension
• Elevated Cardiovascular Risk

Interventions

• BEHAVIORAL

No Results Yet

NCT04826341 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

35 participants

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-09-20

Completion:

2028-03-01

Conditions

• HRD Cancer
• SCLC
• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04825587 | RECRUITING | NA

240 participants

The Pediatric ALL Evaluation and Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-04-28

Completion:

2030-04-01

Conditions

• ACL Injury
• ACL Tear

Interventions

• PROCEDURE

No Results Yet

NCT04822272 | COMPLETED | NA

70 participants

MagneThermoPro : Magnetic Resonance Thermography of Human Prostate

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-07-08

Completion:

2023-06-08

Conditions

• Prostate Cancer Diagnosis

Interventions

• DEVICE

No Results Yet

NCT04799301 | RECRUITING | PHASE1

60 participants

Developing Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar Intake

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-02-23

Completion:

2028-01-01

Conditions

• Diet Therapy
• Healthy Volunteers

Interventions

• BEHAVIORAL

No Results Yet

NCT04772170 | RECRUITING

1000 participants

Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2023-10-23

Completion:

2026-06-02

Conditions

• Influenza
• Respiratory Virus
• Coronavirus

No Results Yet

NCT04751370 | ACTIVE_NOT_RECRUITING | PHASE2

31 participants

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-02-08

Completion:

2026-12-31

Conditions

• Locally Advanced Rectal Adenocarcinoma
• Stage II Rectal Cancer AJCC v8
• Stage III Rectal Cancer AJCC v8

Interventions

• PROCEDURE
• BIOLOGICAL
• RADIATION

No Results Yet

NCT04743245 | TERMINATED | NA

17 participants

Delivery SSO2 Therapy for 60 Min in Anterior MI Patients With PCI ≤ 6 Hours of Symptoms Onset Compared to Standard.

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-08-02

Completion:

2026-04-10

Conditions

• Acute Myocardial Infarction
• STEMI

Interventions

• DEVICE

No Results Yet

NCT04742894 | RECRUITING | NA

100 participants

Neural Bases of Vocal Sensorimotor Impairment in Aphasia

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-07-11

Completion:

2027-02-28

Conditions

• Aphasia

Interventions

• BEHAVIORAL

No Results Yet

NCT04739800 | ACTIVE_NOT_RECRUITING | PHASE2

120 participants

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-06-10

Completion:

2023-01-26

Conditions

• Fallopian Tube Mucinous Adenocarcinoma
• Ovarian Seromucinous Carcinoma
• Platinum-Refractory Fallopian Tube Carcinoma
• Platinum-Refractory Ovarian Carcinoma
• Platinum-Refractory Primary Peritoneal Carcinoma
• Recurrent Fallopian Tube Clear Cell Adenocarcinoma
• Recurrent Fallopian Tube Endometrioid Adenocarcinoma
• Recurrent Fallopian Tube High Grade Serous Adenocarcinoma
• Recurrent Fallopian Tube Mucinous Adenocarcinoma
• Recurrent Fallopian Tube Transitional Cell Carcinoma
• Recurrent Fallopian Tube Undifferentiated Carcinoma
• Recurrent Low Grade Fallopian Tube Serous Adenocarcinoma
• Recurrent Ovarian Clear Cell Adenocarcinoma
• Recurrent Ovarian Endometrioid Adenocarcinoma
• Recurrent Ovarian High Grade Serous Adenocarcinoma
• Recurrent Ovarian Low Grade Serous Adenocarcinoma
• Recurrent Ovarian Mucinous Adenocarcinoma
• Recurrent Ovarian Seromucinous Carcinoma
• Recurrent Ovarian Transitional Cell Carcinoma
• Recurrent Ovarian Undifferentiated Carcinoma
• Recurrent Platinum-Resistant Fallopian Tube Carcinoma
• Recurrent Platinum-Resistant Ovarian Carcinoma
• Recurrent Platinum-Resistant Primary Peritoneal Carcinoma
• Recurrent Primary Peritoneal Clear Cell Adenocarcinoma
• Recurrent Primary Peritoneal Endometrioid Adenocarcinoma
• Recurrent Primary Peritoneal High Grade Serous Adenocarcinoma
• Recurrent Primary Peritoneal Low Grade Serous Adenocarcinoma
• Recurrent Primary Peritoneal Transitional Cell Carcinoma
• Recurrent Primary Peritoneal Undifferentiated Carcinoma
• Refractory Fallopian Tube Clear Cell Adenocarcinoma
• Refractory Fallopian Tube Endometrioid Adenocarcinoma
• Refractory Fallopian Tube High Grade Serous Adenocarcinoma
• Refractory Fallopian Tube Mucinous Adenocarcinoma
• Refractory Fallopian Tube Transitional Cell Carcinoma
• Refractory Fallopian Tube Undifferentiated Carcinoma
• Refractory Low Grade Fallopian Tube Serous Adenocarcinoma
• Refractory Ovarian Clear Cell Adenocarcinoma
• Refractory Ovarian Endometrioid Adenocarcinoma
• Refractory Ovarian High Grade Serous Adenocarcinoma
• Refractory Ovarian Low Grade Serous Adenocarcinoma
• Refractory Ovarian Mucinous Adenocarcinoma
• Refractory Ovarian Seromucinous Carcinoma
• Refractory Ovarian Transitional Cell Carcinoma
• Refractory Ovarian Undifferentiated Carcinoma
• Refractory Primary Peritoneal Clear Cell Adenocarcinoma
• Refractory Primary Peritoneal Endometrioid Adenocarcinoma
• Refractory Primary Peritoneal High Grade Serous Adenocarcinoma
• Refractory Primary Peritoneal Low Grade Serous Adenocarcinoma
• Refractory Primary Peritoneal Transitional Cell Carcinoma
• Refractory Primary Peritoneal Undifferentiated Carcinoma

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

Results Available

NCT04739072 | RECRUITING

1000 participants

Minimal Residual Disease Assessment in Patients With Colorectal Cancer, the MiRDA-C Study

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2019-11-22

Completion:

2028-12-31

Conditions

• Colorectal Adenocarcinoma
• Stage I Colorectal Cancer AJCC v8
• Stage II Colorectal Cancer AJCC v8
• Stage IIA Colorectal Cancer AJCC v8
• Stage IIB Colorectal Cancer AJCC v8
• Stage IIC Colorectal Cancer AJCC v8
• Stage III Colorectal Cancer AJCC v8
• Stage IIIA Colorectal Cancer AJCC v8
• Stage IIIB Colorectal Cancer AJCC v8
• Stage IIIC Colorectal Cancer AJCC v8
• Stage IV Colorectal Cancer AJCC v6
• Stage IVA Colorectal Cancer AJCC v8
• Stage IVB Colorectal Cancer AJCC v8
• Stage IVC Colorectal Cancer AJCC v8

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT04609046 | RECRUITING | PHASE1

47 participants

Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-05-24

Completion:

2027-04-01

Conditions

• Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT04597710 | COMPLETED

200 participants

Precision Medicine for Liver Tumours With Quantitative Magnetic Resonance Imaging and Whole Genome Sequencing

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2021-02-18

Completion:

2025-12-31

Conditions

• Liver Cancer
• Liver Metastasis Colon Cancer

Interventions

• GENETIC

No Results Yet

NCT04595474 | ACTIVE_NOT_RECRUITING

533 participants

Prevalence of NAFLD and Advanced Fibrosis in Patients With Type 1 Diabetes

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2021-01-14

Completion:

2022-08-19

Conditions

• Nonalcoholic Fatty Liver
• Nonalcoholic Steatohepatitis
• Fibrosis, Liver
• Type 1 Diabetes
• Cirrhosis, Liver

Interventions

• DEVICE

No Results Yet

NCT04586075 | RECRUITING

1000 participants

UW Undiagnosed Genetic Diseases Program

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2021-07-16

Completion:

2030-10-31

Conditions

• Rare Diseases
• Genetic Disease
• Undiagnosed Disease

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04579224 | ACTIVE_NOT_RECRUITING | PHASE3

184 participants

Comparing the New Anti-cancer Drug Eribulin With Chemotherapy Against the Usual Chemotherapy Alone in Metastatic Urothelial Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-06-28

Completion:

2030-08-15

Conditions

• Metastatic Bladder Urothelial Carcinoma
• Metastatic Urothelial Carcinoma
• Refractory Bladder Urothelial Carcinoma
• Refractory Urothelial Carcinoma
• Stage IV Bladder Cancer AJCC v8

Interventions

• PROCEDURE
• DRUG
• BIOLOGICAL

No Results Yet

NCT04561518 | RECRUITING

1500 participants

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2020-11-23

Completion:

2033-12-31

Conditions

• Transthyretin-Mediated Amyloidosis
• ATTR Amyloidosis

No Results Yet

NCT04557969 | RECRUITING

400 participants

Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2020-12-18

Completion:

2040-12-30

Conditions

• Gastric Cancer
• Gastric Neoplasm
• Gastrointestinal Stromal Sarcoma
• Gastrointestinal Stromal Neoplasm
• Gastrointestinal Stromal Tumor (GIST)

No Results Yet

NCT04548752 | ACTIVE_NOT_RECRUITING | PHASE2

88 participants

Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-02-22

Completion:

2026-10-01

Conditions

• Metastatic Pancreatic Adenocarcinoma
• Stage IV Pancreatic Cancer AJCC v8

Interventions

• BIOLOGICAL
• PROCEDURE
• DRUG

No Results Yet

NCT04541030 | ACTIVE_NOT_RECRUITING

241 participants

Integrated Genomic Prostate Score With MRI Targeted Prostate Biopsies

Study Type:

OBSERVATIONAL

Last Updated:

2026-05-29

Start Date:

2020-09-02

Completion:

2027-07-01

Conditions

• Prostate Cancer

No Results Yet

NCT04532970 | COMPLETED | NA

651 participants

BAPS in Botswana: The Thotloetso Trial

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-05-06

Completion:

2025-12-01

Conditions

• HIV Infections
• Smoking Cessation
• Smoking

Interventions

• BEHAVIORAL

No Results Yet

NCT04530552 | ACTIVE_NOT_RECRUITING | PHASE2

34 participants

Testing the Effects of Low Dose Apalutamide on Prostate-Specific Antigen (PSA) Levels in Men Scheduled for Removal of the Prostate Gland

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-07-23

Completion:

2024-11-06

Conditions

• Localized Prostate Carcinoma
• Prostate Adenocarcinoma
• Stage I Prostate Cancer AJCC v8
• Stage II Prostate Cancer AJCC v8

Interventions

• DRUG
• PROCEDURE
• OTHER

Results Available

NCT04526665 | ACTIVE_NOT_RECRUITING | PHASE3

161 participants

Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2020-09-24

Completion:

2023-06-01

Conditions

• Primary Biliary Cirrhosis

Interventions

• DRUG

Results Available

NCT04519801 | COMPLETED | NA

60 participants

BFR Therapy for Post-Op Rehab of ACL Reconstruction With Quadriceps Tendon Autograft

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-09-09

Completion:

2026-02-13

Conditions

• ACL Injury

Interventions

• OTHER

No Results Yet

NCT04517903 | COMPLETED | NA

292 participants

Validation Study on Eye Rubbing Questionnaire in Patients With or Suspected of Having a Keratoconus (KC)

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-03-16

Completion:

2021-10-13

Conditions

• Keratoconus

Interventions

• OTHER

No Results Yet

NCT04508790 | RECRUITING | PHASE2

29 participants

Leflunomide, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2020-11-24

Completion:

2027-02-14

Conditions

• Recurrent Plasma Cell Myeloma
• Refractory Plasma Cell Myeloma

Interventions

• DRUG

No Results Yet

NCT04496895 | RECRUITING | NA

124 participants

The Evaluation of Orange Peel Fermentation on Body Fat Lowering Efficacy in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-11-12

Completion:

2026-09-30

Conditions

• Overweight
• Fatty Liver Disease

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04492605 | ACTIVE_NOT_RECRUITING | NA

96 participants

The Evaluation of TCI378 and TCI507 Probiotics on Weight-lowering Efficacy in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2022-03-09

Completion:

2025-10-16

Conditions

• Weight Loss

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04484337 | COMPLETED | PHASE1

138 participants

Study to Evaluate Pharmacokinetic (PK), Safety and Tolerability of Cabotegravir (CAB) 400 Milligrams Per Milliliter (mg/mL) Formulation in Healthy Adult Participants

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2020-07-31

Completion:

2023-05-05

Conditions

• HIV Infections

Interventions

• DRUG

Results Available

NCT04480853 | RECRUITING | PHASE4

30 participants

Safety and Efficacy Study of Fingolimod in Taiwanese Adults (≥ 20years) With Relapsing Remitting Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2020-10-12

Completion:

2027-09-30

Conditions

• Multiple Sclerosis

Interventions

• DRUG

No Results Yet

NCT04465643 | COMPLETED | PHASE1

13 participants

Neoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath Tumor

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-06-08

Completion:

2025-07-30

Conditions

• Nerve Sheath Tumors

Interventions

• DRUG

No Results Yet

NCT04460235 | RECRUITING | PHASE4

160 participants

Clinical Trial Assessing the Immunogenicity of an Anti-pneumococcal Vaccination Strategy (PCV13+PPV23 Versus PREVENAR20) in Adult Patients Treated for a Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2026-05-29

Start Date:

2021-09-07

Completion:

2028-06-30

Conditions

• Vaccine
• Streptococcus Pneumoniae
• Lymphoma, Non-Hodgkin

Interventions

• BIOLOGICAL

No Results Yet